Mycobacterium avium subsp. avium: MAA44156_02218
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Entry
MAA44156_02218 CDS
T10718
Symbol
aceE
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mavm Mycobacterium avium subsp. avium
Pathway
mavm00010
Glycolysis / Gluconeogenesis
mavm00020
Citrate cycle (TCA cycle)
mavm00620
Pyruvate metabolism
mavm00785
Lipoic acid metabolism
mavm01100
Metabolic pathways
mavm01110
Biosynthesis of secondary metabolites
mavm01120
Microbial metabolism in diverse environments
mavm01200
Carbon metabolism
mavm01210
2-Oxocarboxylic acid metabolism
Module
mavm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mavm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MAA44156_02218 (aceE)
00020 Citrate cycle (TCA cycle)
MAA44156_02218 (aceE)
00620 Pyruvate metabolism
MAA44156_02218 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MAA44156_02218 (aceE)
Enzymes [BR:
mavm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MAA44156_02218 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QGW32437
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Position
2363798..2366587
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AA seq
929 aa
AA seq
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MTTEFVRHDLATNPTGPAEPDRVRVIREGVASYLPDIDPEETSEWLESFDELLERSGPSR
ARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQIFIQGHASPGIYARAF
LEGRLTADQLDGFRQEHSHAGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVENMTDAEIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLALEDLKHFRDAMRIPISDAQLDENPYLPPYYHPGSDAP
EIRYMLDRRRTLGGFLPERRTKAKALRLPGRDIYAALKKGSGTQEVATTMATVRTFKEVL
RDKEIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAADQMTRGFLLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLARMFGENPEDVY
FYITVYNEPYVQPPEPENFDPEGLLRGLYRYHVATEQRANKAQILASGVAMPSALSAAKM
LADEWDVAADVWSVTSWGELNRDGVAIDRARLRHPDRPAGVPYVTQALSDASGPVVAVSD
WMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARDGEID
PSVPVAAARQYRIDDVLAAPEQTSDPGVA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgacaaccgaattcgtgcgccacgatctggccacaaaccccaccggcccggccgaaccc
gaccgcgtccgggtgatccgcgagggggtcgcgtcctacctccccgacatcgatccggaa
gagacgtcggagtggctggagtccttcgacgaactgctggagcgctccgggccgtcgcgg
gcccgctatctgatgctgcggctgctcgaacgcgccggcgagcagcgggtcgccatcccg
tcgctgacctccaccgactacgtcaacaccattcccaccgaactcgagccgtggttcccc
ggcgacgaggacgtcgaacggcgctaccgggcgtggatccggtggaacgccgccatcatg
gtgcaccgcgcgcagcggccgggagtcggtgtgggcggccacatttcgacctacgcgtcg
tcggcggcgctgtacgaagtcggcttcaaccacttcttccgcggcaagtcgcatcccggc
ggcggcgaccagatcttcatccaggggcacgcctccccggggatctacgcgcgcgccttc
ctggagggccggttgaccgccgaccaactcgacggcttccgccaggagcacagccacgcc
ggcggcggcctgccgtcctacccgcacccacggctgatgcccgacttctgggaattcccc
acggtgtcgatgggcctgggcccactgaacgccatttatcaggcgcggttcaaccactac
ctacatgaccgcggcatcaaggacacctccgatcagcacgtgtggtgcttcttgggcgac
ggcgagatggacgagccggaaagccgcgggctgatccaggtggccgccaacgaggcgctg
gacaacctgacgttcgtgatcaactgcaacctgcagcgcctcgacggcccggtgcgcggc
aacggcaagatcattcaggaactggagtcgttcttccgcggcgccggctggaacgtcatc
aaggtggtctggggccgcgagtgggacgccctgctgcacgccgaccgggacggcgcgctg
gtgaacctgatgaacaccacgcccgacggggattaccagacctacaaggccaacgacggc
gcctacgtgcgcgaccatttcttcggccgcgacccgcgcaccaaggcgctggtggagaac
atgaccgacgccgagatctggaacctcaagcgcggcggccacgactaccgcaaggtgtat
gccgcctaccgggccgccgtcgaccacaagggccagcccacggtgatcttggccaagacc
atcaagggctactcgctgggcgcgcacttccagggccgcaacgccacgcatcagatgaaa
aagcttgcgctggaagacctcaagcacttccgggacgcgatgcgcattccgatcagcgac
gcccagctggacgagaacccctacctgccgccctactaccaccccggctccgacgccccg
gagatccgctacatgctcgaccggcgccgcaccctgggcggctttctgcccgaacgccgc
accaaggcaaaggcattgcggcttcccggccgcgacatctacgccgcgctgaagaagggg
tcgggcacccaggaggtcgccaccaccatggcgacggtgcgcaccttcaaagaagtgttg
cgggacaaggagatcggcccgcggatcgtgccgatcattcccgacgaggcgcgcaccttc
ggcatggactcctggttcccgtcgctgaagatctacaaccgcaacggccagctgtacacc
gccgtggacgccgaattgatgttggcgtacaaggaaagcgaagtcgggcagatcctgcac
gagggcatcaacgaggccgggtcggtgggatcgttcatcgcggccgggacgtcgtatgcg
acgcacaacgagccgatgatcccgatctacatcttctattcgatgttcggcttccagcgc
accggtgacgggctgtgggccgccgccgaccagatgacgcgcggcttcctgctcggcgcg
acggccgggcgcaccaccctgaccggcgagggcctgcaacacgccgacggccactcgctg
ctgctggccgccaccaacccggccgtggtcgcctacgacccggcgttcgcctacgagatc
gcctacatcgtggagagcgggctggcgcggatgttcggcgagaaccccgaggacgtgtac
ttctacatcacggtctacaacgagccgtacgtgcagccgccggagccggagaacttcgat
cccgaaggtctgctgcgcggcctctaccgctaccacgtggccaccgaacagcgcgccaac
aaggcgcagatcctggcctccggagtggccatgccgtcggcgctgagcgcggcgaagatg
ctggccgacgagtgggacgtggccgccgacgtgtggtcggtgaccagctggggcgagttg
aaccgcgacggcgtggcgatcgaccgggccaggctgcggcacccggaccggcccgccggc
gtcccctacgtcacgcaggcgctgtcggatgccagcgggccggtggtcgccgtgtcggac
tggatgcgggcggtccccgagcagatccggccgtgggtgccgggcacctacgtgacgctg
ggcaccgacgggttcggcttctccgacacccggcccgcggcgcggcggtacttcaacacc
gacgccgagtcgcaggtggtcgcggtgctcgaggcgctggcgcgcgacggcgagatcgac
ccgtcggtgccggtcgccgccgcacgccagtaccgcatcgacgacgtgctggccgccccc
gagcagacgtccgaccccggcgtggcctaa
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