Mycolicibacterium brumae: L2Z93_000925
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Entry
L2Z93_000925 CDS
T08531
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mbrm
Mycolicibacterium brumae
Pathway
mbrm00020
Citrate cycle (TCA cycle)
mbrm00630
Glyoxylate and dicarboxylate metabolism
mbrm00785
Lipoic acid metabolism
mbrm01100
Metabolic pathways
mbrm01110
Biosynthesis of secondary metabolites
mbrm01120
Microbial metabolism in diverse environments
mbrm01200
Carbon metabolism
mbrm01210
2-Oxocarboxylic acid metabolism
Module
mbrm_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mbrm_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mbrm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
L2Z93_000925
00630 Glyoxylate and dicarboxylate metabolism
L2Z93_000925
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
L2Z93_000925
Enzymes [BR:
mbrm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
L2Z93_000925
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
L2Z93_000925
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
L2Z93_000925
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
L2Z93_000925
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UWW07890
LinkDB
All DBs
Position
complement(895298..899038)
Genome browser
AA seq
1246 aa
AA seq
DB search
MSSTSSPFGQNEWLVEEMYRKFREDPKSVDPSWHEFLVDYNPGKLSEGIVDNGQQAEKPA
AQKPAPESKPAPAETKPSPEAALPAKTPPTSTGASAPDMAPPATKPAPAPKAASDSPAGE
EQTQVLRGVAAAVVKNMNTSLEVPTATSVRAIPAKLMIDNRTVINNHLKRTRGGKISFTH
LLGYAIVQGVKAFPNMNRHFAEIDGKPNAVTPAHTNLGLAIDLPGKNGNRSLVVAAIKGC
ETMKFGEFIAAYEDIVRRARDGKLTAEDFAGVTISLTNPGTLGTVHSVPRLMAGQGAIIG
AGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTVHRHLLDDGFW
DEIFFELGIPYEPVRWRIDNPDSIEQKNARVIELIAAYRNRGHLMADIDPLRLDATRFRS
HPDLDVNTHGLTLWDLDRVFRVDGFAGQQHKKLRDVLSVLRDAYCRHVGVEYTHILEPEQ
QKWLQERIEVRHDKPTVAQQKYILSRLNAAEAFETFLQTKYVGQKRFSLEGAETIIPMMD
AAIDQAAEHGLDEVVIAMPHRGRLNVLANIVGKPYAQIFTEFEGNLNPSQAHGSGDVKYH
LGASGNYLQMFGDNEIEVSLTANPSHLEAVDPVLEGIVRAKQDLLNKGDGPDGFTVMPLM
LHGDAAFAGQGVVAETLNLAMLRGYRVGGTIHMVVNNQIGFTTSPENSRSSEYCTDVAKM
IGAPIFHVNGDDPEACDWVSRLAVDFRQKFKKDVVIDMLCYRRRGHNEGDDPSMTQPAMY
DVIDHKRGVRKTYTEALIGRGDISIQEAEAALRDFQGQLEQVFNEVRELEKFVPEPSESV
ETEQTITHGLNTAVDKAMLARIGDAHLAVPEGFSVHPRVKPVLDKRREMAYEGKVDWAFG
ELLALGSLIADGKLIRFSGQDTRRGTFTQRHAVIIDRKTGEEFTPLQLLAANEDGTSTGG
KFLIYNSALSEFAAVGFEYGYAVGNREAVVLWEAQFGDFVNGAQSVIDEFVSSGEAKWGQ
TSDVVLLLPHGHEGQGPDHTSGRIERFLQLCAEGSMTVAQPSTPANYFHLLRRHALGGIH
RPLIVFTPKSMLRNKAAVSDVKDFTEVKFRSVLEEPTYEDGIGDRSKVTRVLMCSGKIYY
DLAARKAKEKREDVAIVRIEQLYPLPPRRLGRTLDQYPNAREFFWVQDEPANQGPWPTFG
LELPELLPDKLSGIKRISRRAMSAPSSGSSKVHAVEQQEILDAAFG
NT seq
3741 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagtacgagttcaccattcggccagaacgagtggctggtcgaggagatgtaccgc
aagttccgcgaggaccccaagtcggtcgacccgagctggcatgagttcctggtcgattac
aaccccgggaagctgagcgaaggcatcgtcgacaacggccagcaggccgagaagccggcg
gcccagaagccggcccccgaatcgaagccggcgcccgcggaaaccaagccgtcgccggag
gccgcgttgcccgccaagaccccgccgaccagcaccggcgcctcggcgcccgatatggcg
ccgccggcgaccaagcccgcgccggcgccgaaggccgcgtcggactcccccgccggcgaa
gagcagacccaggtgctgcgcggtgtcgccgccgccgtcgtcaagaacatgaacacctcg
ctggaggtgccgacggcgaccagtgtccgggccatcccggccaagctgatgatcgacaac
cggacggtcatcaacaatcacctcaagcgcacccgcggcggcaagatcagcttcacccac
ctgctggggtacgcgatcgtgcagggcgtcaaggcgttcccgaacatgaaccggcacttc
gccgagatcgacggcaagccgaatgcggtcaccccggcgcacaccaacctgggcctggcc
atcgacctgccgggcaagaacggcaatcgttccctggtcgtcgcggcgatcaagggctgc
gagacgatgaagttcggcgagttcatcgccgcctacgaagacatcgtgcggcgcgcccgc
gacggcaagctgaccgctgaggacttcgccggtgtgaccatctcgctgaccaacccgggc
acgctgggcaccgtgcactcggtgccccggctgatggccggccagggcgcgatcatcggc
gccggggccatggagtacccggcggagttccagggcgccagtgaggagcggatcgccgag
ctgggtatcggcaagctgatcaccctgacctcgacgtatgaccaccgcatcatccagggc
gcggagtccggggacttcctgcgcaccgtccaccggcacctgctcgacgacggcttctgg
gacgagatcttcttcgaactcggcatcccctatgagccggtgcgctggcggatcgacaac
cccgattcgatcgagcagaagaacgcccgcgtcatcgagctgatcgcggcctaccgcaac
cgcggccacctgatggccgacatcgacccgctgcgcctggacgccacccggttccgcagc
cacccggacctggacgtcaacacccacggcctgacgctgtgggatctggaccgggtcttc
cgggtcgacgggttcgccggccagcagcacaagaagttgcgcgacgtgctctcggtgctg
cgcgacgcctactgccggcacgtcggcgtggagtacacccacatcctggagcccgagcag
cagaagtggctgcaggagcgcatcgaggtgcgtcacgacaagccgacggtcgcgcagcag
aagtacatcctgagccggctcaacgccgccgaggcgttcgagacgttcctgcagaccaag
tacgtcggacagaagcggttctccctggagggcgcggagaccatcatcccgatgatggac
gcggccatcgaccaggccgccgagcacggcctggacgaggtcgtcatcgccatgccgcac
cgcggccggctcaacgtgctggccaatatcgtcggcaagccgtacgcgcagatcttcacc
gaattcgagggcaacctgaacccgtcgcaggcgcacggctccggtgacgtgaagtaccac
ctgggcgcctccggcaactacctgcagatgttcggcgacaacgagatcgaggtgtcgctg
acggccaacccgagccacctggaggccgtcgacccggtgctggagggcatcgtccgcgcc
aagcaggacctgctgaacaagggcgacgggcccgacgggttcaccgtgatgccgctgatg
ctgcacggcgacgcggcgttcgccggccagggcgtggtggccgagacgctgaacctggcg
atgctgcgcggctaccgcgtcggcggcaccatccacatggtggtgaacaaccagatcggc
ttcaccacctcgccggagaactcgcggtccagcgagtactgcaccgacgtggcgaagatg
atcggcgcgccgatcttccacgtcaacggcgacgacccggaggcctgcgactgggtgtcc
cggctcgcggtggacttcaggcagaagttcaagaaggacgtcgtcatcgacatgctgtgc
taccgccgccgcgggcacaacgagggcgatgacccgtcgatgacccagccggcgatgtac
gacgtgatcgatcacaagcgcggcgtccgcaagacctacaccgaggcgctgatcggccgc
ggcgacatctcgatccaggaggccgaggccgcgctgcgcgacttccagggccagctggag
caggtgttcaacgaggtccgcgagctggagaagttcgttccggagcccagcgagtcggtg
gagaccgagcagaccatcacccacgggctgaacaccgccgtggacaaggccatgctggcc
cggatcggcgacgcgcacctggcggtgccggagggcttctccgtgcacccgcgggtcaag
ccggtgctggacaagcgtcgcgagatggcctacgagggcaaggtcgactgggctttcggc
gagctgctggcgctggggtcgctgatcgccgacggcaagctgatccggttctccggccag
gacacccgccgcggcacgttcacccagcggcacgcggtgatcatcgaccgcaagaccggc
gaggagttcaccccgctgcagctgctggcggccaatgaggacggcacctccaccggtggg
aagttcctgatctacaactcggcgctgagcgagttcgccgcggttgggttcgagtacggc
tacgccgtcggcaaccgcgaggccgtggtgctgtgggaggcgcagttcggcgacttcgtc
aacggcgcgcagtcggtgatcgacgagttcgtcagctctggcgaggccaagtggggccaa
acctccgatgtggtgctgctgctgccgcacggccacgagggccagggtcccgaccacacc
tccgggcgcatcgagcgattcctgcagctgtgcgcggaagggtcgatgaccgtcgcccag
ccgtcgaccccggcgaactacttccacctgctgcggcggcacgcgctcggtggcatccac
cggccgctgatcgtcttcaccccgaagtcgatgctgcggaacaaggcggcggtcagcgac
gtgaaggacttcaccgaggtgaagttccgctcggtgctggaggagccgacctacgaggac
ggcatcggcgaccgcagcaaggtcacccgggtgctgatgtgctccggcaagatctactac
gacctggcggcgcgcaaggccaaggagaagcgcgaggacgtcgcgatcgtgcggatcgag
cagctctacccgctgccgccgcgccgcctcggccgcaccctggaccagtacccgaacgcc
cgggagttcttctgggtgcaggacgagccggccaaccaggggccgtggccgacgttcggc
ctggagcttcccgaactgctgccggacaagctgtccggtatcaagcggatctcgcgccgc
gcgatgagcgcgccgtcctcgggttcgtcgaaggtgcatgccgtcgaacagcaggagatt
ctcgacgccgcgttcggctga
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