Micromonospora carbonacea: HXZ27_26240
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Entry
HXZ27_26240 CDS
T06722
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mcab
Micromonospora carbonacea
Pathway
mcab00020
Citrate cycle (TCA cycle)
mcab00630
Glyoxylate and dicarboxylate metabolism
mcab00785
Lipoic acid metabolism
mcab01100
Metabolic pathways
mcab01110
Biosynthesis of secondary metabolites
mcab01120
Microbial metabolism in diverse environments
mcab01200
Carbon metabolism
mcab01210
2-Oxocarboxylic acid metabolism
Module
mcab_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mcab_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mcab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
HXZ27_26240
00630 Glyoxylate and dicarboxylate metabolism
HXZ27_26240
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HXZ27_26240
Enzymes [BR:
mcab01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
HXZ27_26240
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
HXZ27_26240
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
HXZ27_26240
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
HXZ27_26240
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QLD27276
UniProt:
A0A7H8XQG8
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All DBs
Position
6298410..6302165
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AA seq
1251 aa
AA seq
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MSTQQTSQENPLAGFGPNEWLVEEMYQRYLADPSSVDSAWHDFFADYRPAPGAATARPDG
QSAKAAPEPAGQQEAAATVAQPAAQAAPAPAKAPAPKASASGAQPTVKPATKPTPARATK
AEPAAKAAAKPTVTGPQTTPLRGVAAKIVQNMDASLSVPTATSVRAVPAKLLVDNRIVIN
NHLARGRGGKVSFTHLIGYAMVRALVEHPEMNNSFAEVDGKPAMVRPEHVNLGIAIDLAK
PDGSRNLVVPSIKGCETMDFRQFWQAYEDVVRRARRNELTMEDYSGTTISLTNPGGIGTV
HSIPRLMTGQSAIIGVGAMEYPAPYQGMSEATLAELAVSKIITLTSTYDHRIIQGAQSGE
FLKVMHELLLGGHGFYDQIFTSLRIPYEPVRWMQDVAVNSEGQINKTARVHELIHAYRVR
GHLMADTDPLEFKIRKHPDLDVLQHGLTLWDLDRVFPVNGFAGKQRMKLRDILGVLRDSY
CRRVGVEYMHIQDPEERRWIQERIERKYEKPTSDEQKHVLNRLNAAEAFETFLQTKYVGQ
KRFSLEGGESLIPLLGEVLESSAEAGLDEVVIGMAHRGRLNVLANIVGKPYEKIFSEFEG
HLDPRSTQGSGDVKYHLGQNGKFTTPDGEHSVKVSVVANPSHLEAVDPVLEGIVRAKQDR
IDLKLEGYTVLPLAVHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVGFTTAPE
HSRSSLYSTDVARMIEAPILHVNGDDPEAVVRVARLAFEYRQAFNKDVVIDMVCYRRRGH
NEGDDPSMSNPQMYKIIDSKRSVRKLYTEELIGRGDITVEDAEELLRDYQAQLERVFKAT
RDAASAPKQAARPRREDEPEPQVATATTAEVVKAVGEAHTTLPEGFTPHKRIQQLLDRRA
KMSVEGNIDWGYGEIIAFGALLHDGVTVRLAGQDSRRGTFVQRHASVVDARTGDDYLPLK
SLTADGERSRFFVHDSLLSEYAAMGFEYGYSVENVNALVCWEAQFGDFVNGAQSVIDEFI
SSGEVKWGQRSAVTLLLPHGHEGQGPDHTSGRPERFLQLCAEDNMRVAMPTTPANHFHLL
RRQALSPKRKPLVVFTPKSLLRHKLCVSPVEDFTTGTFAPVLADTAAPPAGQVKRVLLCS
GKVYYDLFQARAERGVTDTAIVRMEQLYPLPVEEIRAALAQYPNAEDFAWVQEEPANQGA
WSFVALNLLEHLSEVRLRRISRPAAAAPAVGSAKMHEVEQNALIEAALPRP
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacccagcagacttcgcaggagaacccactggcgggtttcggccctaacgagtgg
ctcgtcgaggagatgtaccagcgttacctcgccgacccgagcagcgtcgattcggcctgg
cacgacttcttcgccgactaccgccccgcgccgggcgccgccacggcacgcccggacggc
cagtccgccaaggccgcgccggagccggccgggcaacaggaggccgccgccaccgtcgcc
cagccggcggcgcaggccgcgccggcccccgcgaaggcccccgcgccgaaggcgtccgcg
tccggggcgcagccgacggtgaagcccgccacgaagccgacgcccgccagagccacgaag
gccgagccggccgcgaaggcggcggcgaagccgacggtgaccggcccgcagaccaccccg
ctgcgcggcgtcgccgcgaagatcgtccagaacatggacgcctcgctgagcgtgccgacc
gcgacgagcgtgcgtgccgtcccggcgaagctgctggtggacaaccgcatcgtgatcaac
aaccacctcgcccgggggcgcggcggcaaggtcagcttcacccacctgatcggttacgcg
atggtccgggcgctcgtcgagcacccggagatgaacaactccttcgccgaggtcgacggc
aagccggcgatggtccgccccgagcacgtcaacctgggcatcgcgatcgacctggccaag
cccgacggcagccgcaacctggtggtgccgtccatcaagggctgcgagacgatggacttc
cggcagttctggcaggcgtacgaggacgtggtccggcgcgcccgccgcaacgagctgacc
atggaggactactcgggcaccacgatctcgctgaccaacccaggcggcatcggcacggtg
cactcgatcccgcgtctgatgacggggcagagcgccatcatcggcgtcggcgcgatggag
tacccggcgccctaccaggggatgagcgaggccaccctcgccgagctggccgtcagtaag
atcatcacgctgaccagcacgtacgaccaccggatcatccagggcgcgcagtccggcgag
ttcctcaaggtcatgcacgagctgctgctcggcgggcacggcttctacgaccagatcttc
acctcgctgcgcatcccgtacgagccggtgcgctggatgcaggacgtggccgtcaactcc
gagggccagatcaacaagaccgcgcgggtgcacgagctgatccacgcgtaccgggtgcgc
ggtcacctgatggccgacaccgacccgctggaattcaagatccgcaagcaccccgacctg
gacgtcctccagcacgggctgaccctgtgggacctggaccgggtcttcccggtcaacggc
ttcgccggcaagcagcggatgaagctgcgcgacatcctcggcgtgctgcgcgactcctac
tgccgccgggtcggcgtggagtacatgcacatccaggacccggaggagcggcgctggatc
caggagcggatcgagcgcaagtacgagaagcccacctccgacgagcagaagcacgtgctc
aaccggctcaacgccgccgaggcgttcgagaccttcctccagacgaagtacgtgggccag
aagcgcttctcgctggagggcggcgagtcgctgatcccgctgctcggcgaggtgctggag
tcctccgccgaggcggggctcgacgaggtcgtcatcggcatggcccaccggggccggctc
aacgtgctggccaacatcgtcggcaagccgtacgagaagatcttctcggagttcgagggg
cacctcgacccgcgctcgacgcagggctcgggcgacgtgaaataccacctcggccagaac
ggcaagttcaccacccccgacggcgagcactccgtcaaggtgtcggtggtggccaacccg
tcgcacctggaggccgtcgacccggtgctggagggcatcgtccgggccaagcaggaccgg
atcgacctcaagctggagggctacaccgtgctgccgctggcggtgcacggtgacgccgcc
ttcgccgggcagggcgtggtcgccgagacgctcaacctgtcgcagctgcgcggctaccgc
accggcggcacggtgcacgtggtggtcaacaaccaggtgggcttcaccaccgcccccgag
cactcccggtccagcctctacagcaccgacgtggcccggatgatcgaggccccgatcctg
cacgtcaacggcgacgaccccgaggccgtggtccgggtcgcccggctggcgttcgaatac
cggcaggcgttcaacaaggatgtcgtgatcgacatggtctgctaccgccggcgcggccac
aacgagggcgacgacccctcgatgtccaacccgcagatgtacaagatcattgactcgaag
cggtcggtccgcaagctctacaccgaggagctgatcggccggggcgacatcaccgtggag
gacgcggaggagctgctgcgcgactaccaggcgcagctggagcgggtcttcaaggccacc
cgggacgccgcctccgcgccgaagcaggcggcccggccgcgccgcgaggacgagccggag
ccgcaggtggcgaccgccacgacggccgaggtcgtcaaggccgtcggcgaggcgcacacc
accctgccggagggcttcaccccgcacaagcggatccagcagctgctcgaccggcgggcc
aagatgtccgtcgagggcaacatcgactgggggtacggcgagatcatcgcgttcggcgcg
ctgctgcacgacggggtcaccgtccggctcgccgggcaggactcccgccggggcacgttc
gtgcagcggcacgcctcggtggtggacgcccgcaccggcgacgactacctgccgctgaag
tcgctcaccgccgacggcgagcggtcccggttcttcgtgcacgactccctgctgtcggag
tacgcggcgatgggcttcgagtacggctactcggtggagaacgtcaacgcgctggtctgc
tgggaggcccagttcggcgacttcgtcaacggcgcgcagtcggtgatcgacgagttcatc
tcctccggcgaggtgaagtggggccagcgctccgccgtcaccctgctgctgccgcacggc
cacgagggccagggcccggaccacacgtccggccgcccggagcggttcctccagctctgc
gccgaggacaacatgcgggtggccatgccgaccaccccggcgaaccacttccacctgctg
cgccgccaggccctgtcgccgaagcgcaagccgctcgtggtgttcacgccgaagtcgctg
ctgcggcacaagctctgcgtgtcgccggtggaggacttcaccacgggcaccttcgccccg
gtgctggccgacaccgccgccccgcccgccgggcaggtgaagcgggtgctgctctgctcg
ggcaaggtctactacgacctgttccaggcccgggccgagcgcggcgtcaccgacaccgcg
atcgtccggatggagcagctctacccgctgcccgtcgaggagatccgggccgccctcgcg
cagtacccgaacgccgaggacttcgcctgggtgcaggaggagccggccaaccagggcgcg
tggagcttcgtcgcgctcaacctgctggagcacctcagcgaggtccggctgcgccgcatc
tcccgccccgccgccgccgcgccggcggtcggctcggcgaagatgcacgaggtcgagcag
aacgcgctgattgaggcggccctgccccgcccgtga
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