KEGG   Mus caroli (Ryukyu mouse): 110285541
Entry
110285541         CDS       T05910                                 
Symbol
Ppp1ca
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal03015  mRNA surveillance pathway
mcal04022  cGMP-PKG signaling pathway
mcal04024  cAMP signaling pathway
mcal04114  Oocyte meiosis
mcal04218  Cellular senescence
mcal04261  Adrenergic signaling in cardiomyocytes
mcal04270  Vascular smooth muscle contraction
mcal04390  Hippo signaling pathway
mcal04510  Focal adhesion
mcal04519  Cadherin signaling
mcal04611  Platelet activation
mcal04720  Long-term potentiation
mcal04728  Dopaminergic synapse
mcal04750  Inflammatory mediator regulation of TRP channels
mcal04810  Regulation of actin cytoskeleton
mcal04910  Insulin signaling pathway
mcal04921  Oxytocin signaling pathway
mcal04931  Insulin resistance
mcal05031  Amphetamine addiction
mcal05034  Alcoholism
mcal05168  Herpes simplex virus 1 infection
mcal05205  Proteoglycans in cancer
mcal05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    110285541 (Ppp1ca)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    110285541 (Ppp1ca)
   04024 cAMP signaling pathway
    110285541 (Ppp1ca)
   04022 cGMP-PKG signaling pathway
    110285541 (Ppp1ca)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    110285541 (Ppp1ca)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    110285541 (Ppp1ca)
   04218 Cellular senescence
    110285541 (Ppp1ca)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    110285541 (Ppp1ca)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    110285541 (Ppp1ca)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110285541 (Ppp1ca)
  09152 Endocrine system
   04910 Insulin signaling pathway
    110285541 (Ppp1ca)
   04921 Oxytocin signaling pathway
    110285541 (Ppp1ca)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110285541 (Ppp1ca)
   04270 Vascular smooth muscle contraction
    110285541 (Ppp1ca)
  09156 Nervous system
   04728 Dopaminergic synapse
    110285541 (Ppp1ca)
   04720 Long-term potentiation
    110285541 (Ppp1ca)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110285541 (Ppp1ca)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    110285541 (Ppp1ca)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    110285541 (Ppp1ca)
  09165 Substance dependence
   05031 Amphetamine addiction
    110285541 (Ppp1ca)
   05034 Alcoholism
    110285541 (Ppp1ca)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    110285541 (Ppp1ca)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    110285541 (Ppp1ca)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mcal01009]
    110285541 (Ppp1ca)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mcal03021]
    110285541 (Ppp1ca)
   03019 Messenger RNA biogenesis [BR:mcal03019]
    110285541 (Ppp1ca)
   03041 Spliceosome [BR:mcal03041]
    110285541 (Ppp1ca)
Enzymes [BR:mcal01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     110285541 (Ppp1ca)
Protein phosphatases and associated proteins [BR:mcal01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     110285541 (Ppp1ca)
Transcription machinery [BR:mcal03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     110285541 (Ppp1ca)
Messenger RNA biogenesis [BR:mcal03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     110285541 (Ppp1ca)
Spliceosome [BR:mcal03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    110285541 (Ppp1ca)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 110285541
NCBI-ProteinID: XP_021007433
Ensembl: MGP_CAROLIEiJ_G0022498
UniProt: A0A6P5P4U6
LinkDB
Position
19:937387..940665
AA seq 330 aa
MSDSEKLNLDSIIERLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactccatcatcgagcgcctgctggaagtgcag
ggctcacggcctgggaagaacgtgcagctgacagagaacgagatccgtggtctgtgcctc
aaatcccgggagattttcctgagccagcccattcttctggagcttgaggcgcctctcaag
atctgtggtgacatccatggccagtactatgaccttctacggctgtttgagtatggtggc
ttccctccagagagcaactacctcttcttgggggattatgtagatcggggcaagcagtct
ttggagaccatctgcctgttgctggcctataagatcagatacccggagaatttctttcta
cttcgtgggaaccatgagtgtgccagcatcaaccgcatttatggcttctatgatgaatgc
aagagaagatacaacatcaagctgtggaagacgttcacagactgcttcaactgcctgccc
attgcagccattgtggatgagaagatcttctgctgccacgggggcctgtctccagacttg
caatccatggagcagattaggcgtattatgcggcccacagatgtgcctgaccagggccta
ctgtgtgatctcctgtggtctgaccctgacaaggatgttcaaggctggggcgagaatgac
cgtggtgtctcctttacctttggggctgaggtggtagccaagttcctgcacaagcatgac
ttggacctcatctgcagagcacatcaggttgtagaagatggctatgagttctttgccaag
agacagttggtgacactcttctcagctcccaactactgtggagagtttgacaatgctggt
gccatgatgagtgtggatgagaccctcatgtgttccttccagatcctcaagcccgctgat
aagaataagggcaagtatgggcagttcagcggcctgaaccccggaggccggcccatcact
ccaccgcgcaattctgccaaagccaagaaatag

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