Mus caroli (Ryukyu mouse): 110290409
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Entry
110290409 CDS
T05910
Symbol
Setx
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
110290409 (Setx)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
mcal03021
]
110290409 (Setx)
Enzymes [BR:
mcal01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
110290409 (Setx)
5.6.2.5 RNA 5'-3' helicase
110290409 (Setx)
Transcription machinery [BR:
mcal03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
110290409 (Setx)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
Helicase_RecD
AAA_16
SLFN-g3_helicase
nSTAND3
Motif
Other DBs
NCBI-GeneID:
110290409
NCBI-ProteinID:
XP_021012595
Ensembl:
MGP_CAROLIEiJ_G0023364
UniProt:
A0A6P5PHL1
LinkDB
All DBs
Position
2:25001165..25058985
Genome browser
AA seq
2697 aa
AA seq
DB search
MSTCCWCTPGGSSTIDVLKRYASSTGSSEFQTADEDLCYCLECVAEYHRARDEVPFLHEV
LWELETLRLVSHFEKSMKAEAEADDDLYIVDNNGEEQLFDCSGQDFENKLRVPLFEILKY
PYLLLHKRVNELCVEALCRMEQNNCSFQVFDKYPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPAHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEKQSDDDSMDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNESYNREIQNIRNSCIRTKLEPEPHFDDMVTCSQIVYNFN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFILILISVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFVRSCEKSPGNTSRGTAIMSSLALHSVQSNSVQLACVQLIR
GLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTGQETHELQMCLKQIIRNIKFKMP
QYSTFGDSTSTFKTPPSFKEESDIIDRKHKKTTYCLENCSPVSSKEPMKADTHRVLMKVN
TTEEENLKQHYIDLNEEEPLPAELCLKQKSEALFSESAQEQVKISTEKSGKESSSYAPPN
STSKNGPEWGCDRGVIMPAHSLTDSSSDFMEQVSTSNGDVSLKDGSVGKTSKPSFKLQKD
EICAKLSHVIKKQIRKSTLVNNINLEENAAISDLENCSGTDRGALKEDSIGHNVPSDPVL
DDKHEEEKSQNSSLFKKEIKSEGLDNSSSDNEDKLEVQEGHADDDLVSFTEVTDTLVKTP
CEGPVKMVVESRDKEMRASTVLTSNLVEGQVPHDSSKPLVAGRQIDLCNITLISQTTVIQ
FPSDLSKQNSFQLQKDDKRCLTANQNSAATCHGQVIVISDSDEEEDEDEDDEDERSCSEE
NIKQSKACIGKDCSEQHGLAVNPNVEKKLVKEEETTCPVEFEDSESQVFEFESSSEVFSV
WQDHKIDSKNSLQGEQKSCVTHVADSTNNNLGCGDSVSEEVVRNKAEGVKEHAGPHSSVS
AEEFCKTGVKKPKRKRRDKVTAEDPQRPSSSVGTEQLPDRRDLTESDLKSADMGMATPSS
SVERDSTVLQKSIKSRTHSKPVRKVPASKATKKTHSDTRRGQSKSSRYISCRTSPAIVPP
KKFRQCPEPTSTVEKLGLKKAPRKAFELSQRSLECIVQLRDHGKTVGVVNAPKKAKLISP
QTLSIKNNKKLLTSQDLQFQRLMRSRSHQKRDFDYKNTVRSVSRIVQGSDVLEADSDEPD
DHRVSEPLAISNEKQLAKCMLSKAEVAEASSDPWVTGITCLVNQCESRVLSGGVPTDVVM
SSASEDPVDGGALTVQVGEVAPVKAAEPESSSDTDDDNLFLTQHDPQDMDLCSQLENKTI
IVAHKKDTVQREDSLSRPQLESLSIPKCKYKDCVETTKNKAEYCPRHSEAKAADDGLFRK
PGLPLSVARPLRPTTTKIFSSSSASRTANLSKSLESTTLQSALKNKSSGEQPNLKVTPPS
SMGSQKPVAEVKSLCNIFHFQTPSSSSKQSYKLTFSENRPTSAASPVNILLPSQSIFDTF
IKEVLKWKYQMFLNFDKCGAPTSLCQSISRPVPVRFQDCAEYFNVFLPLIILNAFETVAQ
EWLSSPNKENFYQLQLRKFPADYKKYWEFLIYLDESELAKQLHPKENDLVFLAPEKSYMD
RHGMQDCSHYYCGYVHKFRRTSVMCSGKAECSLCIQTQDTLPASVNKLTRCIVISSLVTT
QRKLKAMSLLSSRNQLARAVLNPNPMDFCTKDLLTTTSERIVAYLKDFNEDQKKAIETAY
AMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENFNAKIKQNRVLVC
APSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINTEVLKFSLDSQVN
HRMKKDLPSHIQEMLRRKEILDAQLDELSRQRALCRGGREMQRQELDEHIVIVSKERQEL
ASKIKEVQGRPQRAQNAIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQS
CEVETLSPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCKLLEENVEQNMI
GRLPVLQLTIQYRMHPDICLFPSNYIYNKNLKTNRLTESIRCSSEWPFQPYLVFDVGDGS
EQRDNDSYINVQEIKLVMEIIKLIKEKRKDISFRNIGIITHYKAQKTMIQKDLEKEFDKK
GLLQPTMMGESRQQDSEASKQQQQKISECMHASDELGSSTVTQSGISSLENGATHTGPAE
VDTVDAFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITRAKYSLFILGHLKTLVE
NQHWYELIQDAQKRGAIIKTCDPNYRHDAMKILKLKPVLQRSLTHPPATAPEAPRPQGGL
PSNRLDSGLATTSFAASLYHTPSDTVTSKGPERPLLQDRLRDPRLLRRLDAEAKGTFLKD
PQPVSPQLPRVVHLLGEPVVFQNLGFVVPPSTAIVAPLGSHRSPIQAEPPPAHPAAAAST
SKRKYSDPDAGLSHRREPRAFSGEQGRHGSMTHHVLRSTDWDRRRLDDSSAKRRQFL
NT seq
8094 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgctgttggtgtactccaggtgggtcttccaccattgatgtcctaaagcgc
tatgcatctagcactgggtcaagtgaatttcagacagctgatgaagatctctgctactgc
ttagagtgtgtggctgagtaccaccgagccagagatgaggtgccgttcttgcacgaggtt
ttgtgggagctagaaaccttacgcctcgtgagtcactttgagaagtccatgaaggcagaa
gctgaagctgatgatgatttatatatagtagacaacaatggagaagaacagctgttcgac
tgtagtggccaagattttgaaaataagcttcgagttcctctttttgaaatactgaagtac
ccttacttacttctgcataagcgtgttaatgaactgtgtgtggaagcgctttgccgaatg
gaacaaaacaattgctcctttcaggtttttgacaaatatccaggcatctatttgtttttg
gttcatcccaatgaaatggttcggcgatgggctattctgactgcaagaaacctggggaag
gtggacagagatgactattacgacttacaggaagttctaacttgcctttttaaagtcatt
gagctggggcttttggaaagtccagacatttacacatcttctgtgcttgaaaaaggcaaa
ctgatccttttgcctgcacacatgtatgatactaccaactacaaaaactattggctaggt
atttgcatgttgttgactattcttgaggagcaagccatggattcactgttgctgggctca
gacaagcaaaatgattttatgcaatcaattcttcacaccatggagaagcaatcggatgat
gatagcatggatcctttctggccagcattacactgtttcatggtgattcttgatcgcctt
ggatctaaggtgtggggtcagcttattgaccctattgaagcttttcaaaccatcattaac
aacgagagctacaacagagagatccagaatatacggaacagctgcataaggaccaagtta
gaaccggagccacattttgatgatatggtgacgtgcagccagattgtttataactttaat
cctgaaaagaccaaaaaggattctgggtggagatcagccatttgtccagattattgtcca
aacatgtatgaagaaatggaaacattagccaatgtacttcagtcagatattggtcaagat
atgcgtgttcataacagcacctttctgtggttcataccttttgttcagtcactcatggat
cttaaggatttgggtgtggcttacatagtagaagttattcatcatctatactcagaagtc
aaagatgtcctcaaccagacagatgctgtgtgtgacaaagtcactgagttttttattctg
attttaatatcagtgattgagctgcatagaaataaaaaatgcttgcatctgctgtgggtg
agttctcagcagtgggtagaagctgttgtgaagtgtgccaagcttcctactaccgcattt
gtacggagttgtgagaagtcacctggaaatacctccagaggaacagcaataatgtcgtcc
ttggcgttgcattcggtgcagtctaactctgtccagcttgcttgtgtacagttgattaga
ggtctcctcaaagaaggttatcagcttggtcagcaaacactttgtaagcggttctgggat
aaacttaacttattccttcgaggaaatttgtctctgggttggcaattgactggtcaagaa
acccatgagttacaaatgtgtttgaaacaaataattagaaacataaaattcaaaatgccc
caatatagcacttttggggattcaacttctacatttaaaacccctccatctttcaaagaa
gaaagtgatataatagacaggaagcataaaaaaaccacttattgcttggaaaattgcagt
ccagtatcttctaaagagccaatgaaagctgacacccatcgagtattgatgaaagtaaat
actacagaagaggagaacttgaagcagcattacattgatttgaatgaagaagagcctctt
ccagctgagttgtgcttgaagcagaaaagtgaggctcttttttctgaaagtgctcaagag
caagttaaaataagcacagagaagtctggaaaagaaagctcttcatatgcaccaccaaat
agtacttcaaaaaatggtccagaatggggatgtgacagaggagtgataatgccagcacat
tcattgactgattctagcagtgattttatggaacaggtatctacatcaaatggagatgtc
tcattaaaggatggctctgttggtaaaacttcaaaaccaagtttcaaattacagaaagat
gaaatttgtgcaaagttatcacatgtcataaagaagcaaatcaggaaaagtactttggta
aataatatcaatctagaggaaaatgcagctatatctgaccttgagaactgttcaggaaca
gatagaggagctctaaaggaagatagcattggacacaatgtgccttcagaccctgttctg
gatgacaagcatgaagaggaaaaatctcaaaacagttcattattcaagaaagagataaag
agtgaggggttggataatagtagttctgacaatgaagacaagcttgaagtccaagaaggc
catgctgacgatgatttggtatcatttacagaagttactgatacactggtgaaaactcca
tgtgagggtcctgtaaagatggtagttgaatcaagagataaggaaatgagagcaagtaca
gtgttgacttctaacttggtagaagggcaggtgcctcatgacagtagcaaacctttggtc
gcaggtcgtcaaatagacctctgtaacataactttaatatctcaaaccactgttattcaa
tttccatcagatttaagtaaacagaattcatttcagctacaaaaagatgataaaagatgt
ttgacagctaaccaaaacagtgctgccacctgccatgggcaagttattgttatttcagat
tctgacgaagaagaggatgaggatgaagatgatgaagatgaaagaagttgtagtgaggaa
aacatcaaacagagtaaagcatgcatagggaaagactgttcagagcagcatggtttggca
gttaatcccaatgtggagaagaagcttgtgaaagaggaagaaacaacgtgccctgtagaa
tttgaagactctgaatctcaggtttttgagtttgaaagctcatctgaagtcttttcagtt
tggcaagatcataaaatagacagcaaaaactcccttcaaggggaacaaaagagctgtgta
actcatgtagctgatagtacaaacaataacttgggttgtggtgactctgtgtctgaagag
gttgttagaaacaaagcagagggagttaaggagcatgcaggaccacatagtagtgtttct
gctgaggaattttgtaaaactggagtaaaaaaacctaagaggaaacgccgtgacaaagtt
acagctgaagatcctcagaggccttcctcttctgttggaactgaacaattgcctgatcgc
agagatcttactgaaagtgatttaaagagtgcagacatggggatggcaactcccagttca
agtgttgagagagattctacagttttacagaagtctataaaatctagaactcactcaaaa
cctgttaggaaagttccagcctctaaggcaactaagaaaacacactcagacaccagaaga
ggacagtctaagagttcacgttacataagttgtagaacttctcctgctattgtgccacca
aagaagtttcgtcagtgtccagagccaacttcaacagttgaaaaacttggtctgaaaaaa
gcccctcggaaggcatttgagttgtcccagaggtctctggagtgtatagtccaattacgt
gaccatgggaagactgttggagtagttaacgcccccaagaaagctaaattaatttctcct
cagactctttctatcaaaaataataagaagcttctgacaagccaggatcttcaatttcaa
aggcttatgagatccagatcacatcaaaaacgagactttgattacaaaaatactgtaaga
tcagtgtcacgcatagtacagggatcagatgtacttgaagcagactctgatgagccagat
gatcatcgagtaagtgagccacttgccatcagtaatgaaaaacagttagcaaaatgcatg
ctttccaaagcagaagtggcagaagcctcttctgatccttgggtgacaggtataacttgt
cttgtgaaccagtgtgaatctagagtgttaagtggaggagtgccaacagatgtggtgatg
tcctctgcttcagaggaccctgtggacggaggtgctctcacagttcaagttggggaggtg
gcacctgtgaaagctgcagagccagagtctagtagtgatacagatgatgacaatttattc
ctaacacaacatgatcctcaagatatggatctgtgctcacagttggaaaataaaaccatt
atcgtggctcataaaaaagacacagtacagagagaagattctttaagtcggcctcagttg
gagtctttgagtatcccaaagtgtaaatacaaagactgtgtcgaaactacaaaaaacaag
gcggaatactgcccaagacactctgaagctaaagcagcagatgacggcctgttccgtaaa
cctggcttgcctctttctgtagccaggcccttgagacctactactaccaagatatttagt
tcaagcagcgcttcacgaactgccaatctttccaagtctttggaaagtactacacttcag
tcagcactaaaaaataagtcaagtggagaacagcctaatttgaaggtgacaccaccctct
tccatgggttctcagaagccagtggctgaggtgaaaagtctatgcaatatttttcatttt
cagactccaagcagttccagcaaacagagttacaagcttacatttagtgagaacaggcct
acatcagctgcttctccagtgaatattctgttgccatcacagtctatctttgacaccttc
attaaagaggtcttaaaatggaaataccaaatgtttttgaactttgataagtgtggtgct
ccaacaagtctctgtcagtctatctcaagacctgtgcctgtccgatttcaagattgtgca
gaatattttaatgtttttctacctttgattatattgaatgcttttgaaacagtggcacag
gaatggctgagctctccaaataaagagaatttctatcagttgcaattacgaaaatttcca
gctgactataaaaaatactgggagtttctgatttacttggacgaatctgaacttgctaaa
cagcttcacccaaaggaaaatgacctggtgtttctggctcctgagaagagttacatggac
aggcatggcatgcaagattgcagccactattactgtggctatgttcataagtttcgtcgc
acttcagtcatgtgcagtgggaaagcggagtgttcattatgcatccagacacaagatacc
ttgccagccagtgtaaataaacttacaagatgcattgtaatcagttctctggtcactaca
cagaggaaattgaaagccatgtctctgttgagtagtcggaaccagttggccagagctgtt
ctaaatccaaaccccatggacttctgtaccaaagatctactaacgacaacttctgaaaga
attgttgcctacttaaaagactttaatgaagaccagaagaaagccatagaaactgcatat
gccatggtgaaacactcaccatccgttgccaaaatctgtctgattcatggaccacctgga
acaggaaaatccaaaactattgttggtctcttgtaccgcttactgacagagaaccagagg
aagggccattcagatgaaaatttcaatgccaaaatcaaacaaaatcgagtcctcgtgtgt
gcaccttccaatgcagcggttgatgaacttatgaaaaaaattatcctcgaatttaaagaa
aaatgtaaagacaagaagaatcctttgggaaactgtggagatataaatttagtacgacta
ggtccagaaaagtctattaatacagaggtcttaaaattcagtttggacagtcaagtcaac
catagaatgaaaaaagacttgccttctcatattcaagaaatgcttagaagaaaagaaatt
ctagatgctcaacttgatgagctttctcgtcagagagctctgtgccgaggtgggcgggag
atgcagaggcaagaattagatgaacacattgtcatagtttcaaaagaaaggcaagaactt
gcttcgaaaattaaagaggttcagggacgcccacagagagcacagaatgcgatcatcttg
gagtcccatgtcatctgctgcacattgagcactagtggtggtttattgcttgagtctgct
tttcgagggcaagggggtgtccccttcagttgtgtcatcgtagatgaggctgggcagtct
tgtgaagttgagacactttctccactcatccaccgctgcaataaacttatcctagtagga
gaccccaaacagctccctcccacagtcatctctatgaaagcacaggagtatggctatgac
cagtcaatgatggcacgattctgcaagctgctggaagagaatgtcgagcagaacatgatt
ggcaggctgccggtgttacagcttaccattcagtacaggatgcatccagacatatgtctc
ttcccttctaattacatttataacaaaaacctgaagacaaatagattgactgaatccatt
cgatgctcatcagagtggccatttcagccctacctcgtgtttgatgttggagatggttca
gaacaacgggataatgactcatatataaatgttcaagaaataaagttggtgatggaaata
attaaacttattaaagagaaaagaaaagatatttccttccgaaatattggcataataacc
cattacaaggctcagaagacgatgatccagaaggatttggagaaagaatttgataagaaa
ggtttattacagcccaccatgatgggggaatcaaggcagcaagactctgaagcatccaag
cagcagcagcagaagatcagtgaatgtatgcatgctagtgatgagctcggttcctccact
gttacacagtccgggatctccagcctagagaatggtgccacccacactggacctgcagaa
gtggacacggtagatgccttccagggccggcagaaagactgtatcattgttacctgtgtc
agggcaagtgctgtgcaaggctcaataggattcctggcaagtttgcagagattgaatgtc
accattacacgagccaagtatagcctctttatccttggacatttgaagactctggtggaa
aaccagcattggtatgaactgattcaggatgctcagaagcgtggggccattattaagacc
tgtgacccaaactatagacatgacgcaatgaagattctgaaactgaagcctgtgctacag
aggagtctgacccatcccccagccactgccccggaggcacccagaccccagggtggcttg
cccagcaacaggctggacagtggacttgccacaacatcttttgctgcttctttgtatcac
acaccctctgatactgtcacttcaaagggacctgaaaggccacttcttcaagaccgactt
cgagatccacgactactcaggagattggatgctgaagccaagggaacattcctgaaggat
ccacagcccgttagcccccagctccccagggtagttcatctcttgggagagcctgtggtt
ttccagaacctaggttttgttgtgccgccatccactgccatcgttgctcctctgggcagc
cacaggtcacctatacaggctgagccaccacctgctcaccctgctgctgccgcctccaca
agtaagaggaagtacagtgacccagatgctgggctcagccacagaagagagcccagggcc
ttcagtggagagcaggggaggcatggctctatgactcatcatgtgctgagaagcactgac
tgggacaggaggaggctggatgacagcagtgccaagaggagacaatttctatag
DBGET
integrated database retrieval system
