KEGG   Mus caroli (Ryukyu mouse): 110290686
Entry
110290686         CDS       T05910                                 
Symbol
Ppp3ca
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X2
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal04010  MAPK signaling pathway
mcal04020  Calcium signaling pathway
mcal04022  cGMP-PKG signaling pathway
mcal04114  Oocyte meiosis
mcal04218  Cellular senescence
mcal04310  Wnt signaling pathway
mcal04360  Axon guidance
mcal04370  VEGF signaling pathway
mcal04380  Osteoclast differentiation
mcal04625  C-type lectin receptor signaling pathway
mcal04650  Natural killer cell mediated cytotoxicity
mcal04658  Th1 and Th2 cell differentiation
mcal04659  Th17 cell differentiation
mcal04660  T cell receptor signaling pathway
mcal04662  B cell receptor signaling pathway
mcal04720  Long-term potentiation
mcal04724  Glutamatergic synapse
mcal04728  Dopaminergic synapse
mcal04921  Oxytocin signaling pathway
mcal04922  Glucagon signaling pathway
mcal04924  Renin secretion
mcal05010  Alzheimer disease
mcal05014  Amyotrophic lateral sclerosis
mcal05020  Prion disease
mcal05022  Pathways of neurodegeneration - multiple diseases
mcal05031  Amphetamine addiction
mcal05152  Tuberculosis
mcal05163  Human cytomegalovirus infection
mcal05166  Human T-cell leukemia virus 1 infection
mcal05167  Kaposi sarcoma-associated herpesvirus infection
mcal05170  Human immunodeficiency virus 1 infection
mcal05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mcal05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110290686 (Ppp3ca)
   04310 Wnt signaling pathway
    110290686 (Ppp3ca)
   04370 VEGF signaling pathway
    110290686 (Ppp3ca)
   04020 Calcium signaling pathway
    110290686 (Ppp3ca)
   04022 cGMP-PKG signaling pathway
    110290686 (Ppp3ca)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    110290686 (Ppp3ca)
   04218 Cellular senescence
    110290686 (Ppp3ca)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    110290686 (Ppp3ca)
   04650 Natural killer cell mediated cytotoxicity
    110290686 (Ppp3ca)
   04660 T cell receptor signaling pathway
    110290686 (Ppp3ca)
   04658 Th1 and Th2 cell differentiation
    110290686 (Ppp3ca)
   04659 Th17 cell differentiation
    110290686 (Ppp3ca)
   04662 B cell receptor signaling pathway
    110290686 (Ppp3ca)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    110290686 (Ppp3ca)
   04921 Oxytocin signaling pathway
    110290686 (Ppp3ca)
   04924 Renin secretion
    110290686 (Ppp3ca)
  09156 Nervous system
   04724 Glutamatergic synapse
    110290686 (Ppp3ca)
   04728 Dopaminergic synapse
    110290686 (Ppp3ca)
   04720 Long-term potentiation
    110290686 (Ppp3ca)
  09158 Development and regeneration
   04360 Axon guidance
    110290686 (Ppp3ca)
   04380 Osteoclast differentiation
    110290686 (Ppp3ca)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110290686 (Ppp3ca)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    110290686 (Ppp3ca)
   05170 Human immunodeficiency virus 1 infection
    110290686 (Ppp3ca)
   05163 Human cytomegalovirus infection
    110290686 (Ppp3ca)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110290686 (Ppp3ca)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    110290686 (Ppp3ca)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110290686 (Ppp3ca)
   05014 Amyotrophic lateral sclerosis
    110290686 (Ppp3ca)
   05020 Prion disease
    110290686 (Ppp3ca)
   05022 Pathways of neurodegeneration - multiple diseases
    110290686 (Ppp3ca)
  09165 Substance dependence
   05031 Amphetamine addiction
    110290686 (Ppp3ca)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110290686 (Ppp3ca)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mcal01009]
    110290686 (Ppp3ca)
Enzymes [BR:mcal01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     110290686 (Ppp3ca)
Protein phosphatases and associated proteins [BR:mcal01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     110290686 (Ppp3ca)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 110290686
NCBI-ProteinID: XP_021012970
Ensembl: MGP_CAROLIEiJ_G0025664
UniProt: A0A6P5P8A7
LinkDB
Position
3:129884124..130150901
AA seq 511 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM
PSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1536 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcgattgatcccaagttgtcgacgaccgacagggtggtgaaagcc
gttccatttccgccaagtcaccggctgacagcaaaggaagtgtttgataatgatgggaaa
cctcgtgtggatatcttaaaagcacatctcatgaaggagggcaggctggaagaaagtgtt
gcattgagaataataacagagggtgcttcgattctccgacaggaaaaaaacttgctggat
atcgacgcaccagtcacagtttgtggggacatccatggacaattctttgacttgatgaag
ctctttgaagtgggaggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgcggaaaccatgaatgtaggcacctcacagagtatttc
acgtttaaacaagaatgtaaaataaagtattcagaacgcgtttatgacgcctgtatggat
gccttcgactgccttcccctggctgcgctgatgaaccagcagttcctgtgtgtacacggt
ggtttgtctccagagattaacactctagacgacatcagaaaattagaccgattcaaagaa
ccacctgcttatgggcccatgtgtgacatcctgtggtcagaccccctggaggactttgga
aatgagaagactcaggaacatttcactcacaacacagtcaggggctgttcgtacttctac
agttatccggctgtgtgtgacttcctgcagcacaataatttgttgtccatactccgcgcc
cacgaagcccaggatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttcccg
tctctaattacaatcttctcagcaccaaattacttagatgtgtacaataacaaagctgca
gtgttgaagtacgagaacaatgtgatgaacatcaggcagttcaactgctccccgcatccg
tactggctcccaaatttcatggatgttttcacctggtcgctgccatttgttggggagaaa
gtgactgagatgctggtcaatgttctcaacatctgctccgacgatgaactggggtcagaa
gaagatggatttgacggagccacggccgcagcccggaaggaagtcatcaggaacaagatc
cgagcaataggcaaaatggccagagtgttctcagttctcagagaagagagtgagagtgtt
ctgacgctgaagggcctgaccccaactggcatgctccccagcggagtgctctctggtggc
aaacagactctgcaaagcgccatcaaaggattttcaccacaacataagatcactagcttc
gaggaggccaagggcttagaccgaattaacgagaggatgccacctcgcagagacgccatg
ccctctgacgccaaccttaactccatcaacaaggctctcgcctcagagactaacggcacg
gacagcaatggcagtaatagcagcaatatccagtga

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