KEGG   Mus caroli (Ryukyu mouse): 110293847
Entry
110293847         CDS       T05910                                 
Symbol
Plcd4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1
  KO
K05857  phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal00562  Inositol phosphate metabolism
mcal01100  Metabolic pathways
mcal04020  Calcium signaling pathway
mcal04070  Phosphatidylinositol signaling system
mcal04919  Thyroid hormone signaling pathway
mcal04933  AGE-RAGE signaling pathway in diabetic complications
Module
mcal_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    110293847 (Plcd4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    110293847 (Plcd4)
   04070 Phosphatidylinositol signaling system
    110293847 (Plcd4)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    110293847 (Plcd4)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    110293847 (Plcd4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mcal04131]
    110293847 (Plcd4)
Enzymes [BR:mcal01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     110293847 (Plcd4)
Membrane trafficking [BR:mcal04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    110293847 (Plcd4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    110293847 (Plcd4)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y EF-hand_like C2 EF-hand_10 PH PH_12 EF-hand_7 EF-hand_6 EF-hand_1 EF-hand_5 GDPD EF-hand_PLCG2 Wap1 EF-hand_15 DUF3939 DUF2057
Other DBs
NCBI-GeneID: 110293847
NCBI-ProteinID: XP_021017354
Ensembl: MGP_CAROLIEiJ_G0014266
UniProt: A0A6P5PMH7
LinkDB
Position
1:68099517..68124063
AA seq 803 aa
MTSQIQDLLATDQDLLLMQEGTMMRKVRTKSWKKLRYFRLQNDGMTVWHGSQPESMPKPT
FSISDVERIRKGQDSELLRYLVEEFPLEQGFTVVFHGRRPNLDLVANSVEEAQIWMRGLQ
LLVDLVASMDHQEQLDQMLHEWFQQADRNQDGRMSFSEAQRLLLLMNVEMDEEYAFSLFQ
EADVTQSDDLGSKEFVQFYKALTKRTEIEEIFEDFSSDKQKLTLLEFVDFLRKEQKEKDH
APDLALELIDRYEPSENGRLLHVLSKDGFLKYLCSKDGNIFNSDCLPIYQDMTQPLSHYY
INSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYHGHTLTSRILF
KDVLATLAQYAFQSSDYPLILSLENHCTWEQQRTMAHHLTEILGEQLLRNTLEGLLIDSM
PSPEQLRGKILVKGKKLRTIEVDKEEEEEEELEKDEGPDLDPASPELETQPQPETQGQAA
GNKKQKKKVMKCPMSCLLICGHVMAQAPSSIPESILLSKQFLLLSSTTIMCPDLSALVVY
LRTVPFCSFTHSKENYHIYDISSFSESKAKNLIKEAGNEFVQHNARQLCRVYPSGLRTDS
SNFNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGGSGYVLKPEFLRDPQSSFNPER
PISLYKAQMLVVQVISGQQLPKVDKTKETTVVDPLVKVELYGVPEDTMEQETSHVENNGI
NPYWGETFYFRLQVPELAMLRFVVKDYSRKSRNNFIGQYTLPWTCMKQGYRHVSLLSRDG
TSLHPASIFVYTCMQEDLDMDEP
NT seq 2412 nt   +upstreamnt  +downstreamnt
atgacatctcagattcaagacctactagccactgatcaggacctgctgctgatgcaagaa
ggcacgatgatgcgcaaggtgaggaccaaaagctggaagaagctaagatacttcagactt
cagaatgacggcatgacagtctggcatggaagtcaaccagaaagcatgcccaagcccact
ttttcgatctctgatgtggagaggatacgtaagggacaggattctgagttgttgcgctat
ctggtggaggagtttcccctggagcaagggttcaccgttgtctttcatgggcgccgcccc
aacctggacctagtggccaacagtgttgaagaggcccagatttggatgcgaggactccag
ctgttggtggatcttgttgccagcatggaccaccaggagcaactggatcaaatgttgcat
gagtggttccagcaagcagacagaaaccaggatggccggatgagtttcagtgaagctcaa
cggctgctgcttctgatgaacgtggaaatggatgaagagtatgccttcagtcttttccag
gaagcagatgttacccaatctgatgatctgggatcaaaagaatttgtccagttctataag
gccctgactaagcgcactgagattgaagaaatatttgaggacttttcatctgacaaacag
aagctgaccttgctggaatttgtggatttcctcagaaaggaacagaaagaaaaagaccat
gctcctgaccttgctctggaactcattgaccgctatgagccctctgagaatggccgattg
ctgcatgtgctgagcaaggatggcttcctcaagtacctctgctcgaaggatggaaacatc
ttcaacagtgactgcctccctatctaccaggatatgactcagcctctgagccactactac
attaactcctctcacaacacctacctagtgggggaccagctttgcgggcagagcagcgtc
gaaggatacatacgggccttgaaacgggggtgccgctgtgtggaggtggacacgtgggat
ggacctgatggagagcccgttgtttatcatgggcataccctgacctctcgcatcctattc
aaagatgtgttggcaacactcgcgcaatatgccttccagtcatcagactaccctctcatc
ttgtctctggaaaaccactgcacctgggaacagcagaggaccatggcacaccatctgacc
gagatcctgggagagcagctgctgaggaacaccctagagggattgctgattgacagcatg
ccctcgccagagcagcttcgggggaagatcttggtgaaaggaaagaagttaagaacaatt
gaagttgacaaggaagaagaagaagaagaagagctggagaaagatgagggaccagatctg
gaccccgcctcccctgagttggaaactcaacctcagcctgagacccaggggcaggccgct
gggaacaagaagcagaagaagaaggttatgaagtgtccgatgtcttgtctgcttatctgt
ggtcatgttatggcccaggctcctagttccattcctgagtccattctcttgtcaaagcag
tttcttctcctgagttccacaaccatcatgtgtccagacctatctgccctggttgtctac
ttgaggactgtccccttctgcagcttcactcattccaaagaaaactaccacatctatgac
atttcatccttttctgagtccaaggccaagaacctcatcaaggaggcaggcaacgagttt
gtacagcacaatgccagacagttatgccgcgtgtatcccagtggtctgaggacagattca
tccaactttaacccccaggaacactggaatgtaggctgccagatggtggctatgaatatg
cagactgcaggaagtgcaatggatatctgtgatgggctcttccgccagaatggtggctct
ggctatgtgctgaagccagaattcctgagagatccccagagttcattcaatcctgagagg
cctattagtctttataaggcccagatgcttgtagtccaggtgattagtggtcaacaactc
cccaaagtggacaaaaccaaagagacaaccgttgtggatccactggtgaaagtagagctc
tatggtgttcctgaagacacaatggagcaagagaccagccatgtggagaataatggtatt
aatccatactggggggagacattctatttccggctccaggtacctgaacttgctatgttg
cgttttgtggtaaaggattatagcaggaaatcccgaaataactttattggccaatacacc
ctgccttggacctgtatgaaacaaggttaccgacatgtatccttgctctccagagatggc
actagcctccatccagcttccatctttgtgtacacctgcatgcaggaagacctggatatg
gatgagccctga

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