Mus caroli (Ryukyu mouse): 110293897
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Entry
110293897 CDS
T05910
Symbol
Nos3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal00220
Arginine biosynthesis
mcal00330
Arginine and proline metabolism
mcal01100
Metabolic pathways
mcal04020
Calcium signaling pathway
mcal04022
cGMP-PKG signaling pathway
mcal04066
HIF-1 signaling pathway
mcal04071
Sphingolipid signaling pathway
mcal04151
PI3K-Akt signaling pathway
mcal04370
VEGF signaling pathway
mcal04371
Apelin signaling pathway
mcal04611
Platelet activation
mcal04915
Estrogen signaling pathway
mcal04921
Oxytocin signaling pathway
mcal04926
Relaxin signaling pathway
mcal04931
Insulin resistance
mcal04933
AGE-RAGE signaling pathway in diabetic complications
mcal05415
Diabetic cardiomyopathy
mcal05417
Lipid and atherosclerosis
mcal05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
110293897 (Nos3)
00330 Arginine and proline metabolism
110293897 (Nos3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
110293897 (Nos3)
04371 Apelin signaling pathway
110293897 (Nos3)
04066 HIF-1 signaling pathway
110293897 (Nos3)
04020 Calcium signaling pathway
110293897 (Nos3)
04071 Sphingolipid signaling pathway
110293897 (Nos3)
04022 cGMP-PKG signaling pathway
110293897 (Nos3)
04151 PI3K-Akt signaling pathway
110293897 (Nos3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110293897 (Nos3)
09152 Endocrine system
04915 Estrogen signaling pathway
110293897 (Nos3)
04921 Oxytocin signaling pathway
110293897 (Nos3)
04926 Relaxin signaling pathway
110293897 (Nos3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110293897 (Nos3)
05418 Fluid shear stress and atherosclerosis
110293897 (Nos3)
05415 Diabetic cardiomyopathy
110293897 (Nos3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
110293897 (Nos3)
04933 AGE-RAGE signaling pathway in diabetic complications
110293897 (Nos3)
Enzymes [BR:
mcal01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
110293897 (Nos3)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
110293897
NCBI-ProteinID:
XP_021017424
Ensembl:
MGP_CAROLIEiJ_G0027006
UniProt:
A0A6P5PQI2
LinkDB
All DBs
Position
5:19279790..19299654
Genome browser
AA seq
1202 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSQAPAPPSPTRPAPDHSPPLTR
PPDGPRFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRPTQGPSPTE
QLLGQARDFINQYYNSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA
PRCVGRIQWGKLQVFDARDCRTAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDF
RIWNSQLIRYAGYRQQDGSVRGDPANVEITELSIQHGWTPGNGRFDVLPLLLQAPDEPPE
LFTLPPEMVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSSE
IGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH
AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK
GSAAKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRL
FRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP
RPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFC
AFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAAR
DIFSPKRSWKRQRYRLSTQAESLQLLPGLTHVHRRKMFQATILSVENLQSSKSTRATILV
RLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPSTEPVAVEQLEKGSPGGPP
PGWVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYE
EWKWFSCPTLLEVLEQFPSVALPAPLILTQLPLLQPRYYSVSSAPSAHPGEIHLTIAVLA
YRTQDGLGPLHYGVCSTWMSQLKAGDPVPCFIRGAPSFRLPPDPNLPCILVGPGTGIAPF
RGFWQDRLHDIEIKGLQPAPMTLVFGCRCSQLDHLYRDEVLDAQQRGVFGQVLTAFSRDP
GSPKTYVQDLLRTELAAEVHRVLCLEQGHMFVCGDVTMATSVLQTVQRILATEGGMELDE
AGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWSFDPPGPEIP
GS
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagccggggccaccctgtggcctagggctcggg
ctgggtttagggctgtgcggcaagcagggcccagcctctccagcaccggagcctagccag
gcgccagcacccccgtctccaacccgaccagcaccagaccacagccccccgctaacccgg
cccccagacggacccaggtttcctcgagtaaagaactgggaagtgggcagcatcacctat
gacaccctcagtgcccaggctcagcaggatgggccctgtaccccaagacgctgcttggga
tccctggtgtttccaaggaagttacagagccggcccacccagggcccttcacccactgag
cagctattgggtcaagcccgggacttcatcaatcagtactataactccatcaaaaggagt
ggctcccaggctcatgagcagcggcttcaggaagtggaggctgaggtggcagccacaggc
acctaccagctccgggagagcgagctggtgtttggggccaagcaggcctggcgcaatgct
ccccgctgtgtgggccggatccagtggggaaagctgcaggtatttgatgctcgggactgc
aggactgcacaggaaatgtttacctacatctgtaaccacattaagtacgcaacaaataga
ggcaatcttcgttcagccatcacagtgttcccccagcgctgccctggccggggggacttc
cggatctggaacagccaactgatacgctatgcgggctatcggcagcaggatggctccgtg
cgaggggaccctgccaatgtggagatcactgagctctctatccaacatggctggacccca
ggaaatggccgctttgatgtgctgcccctgctactccaggctcctgatgagcccccagaa
ctcttcactctgcccccagagatggtcctcgaggtgcctctggagcaccccacgctcgag
tggtttgctgcccttggcctgcgctggtatgccctcccagctgtgtccaacatgctgcta
gaaatcgggggcctggagtttcctgctgcccctttcagcggctggtacatgagttcagag
attggcatgagggacctctgtgaccctcaccgctacaacatacttgaggatgtggctgtc
tgcatggatctagacaccaggacaacctcatccctgtggaaagacaaggcagcggtggaa
attaatgtggccgtgctgcacagttaccagctggccaaagtgaccatagtagaccaccac
gccgccacagcctccttcatgaagcacctggaaaatgagcagaaggccagagggggctgc
cctgccgattgggcctggattgtgccccccatctcaggcagcctaactcctgtcttccat
caagagatggtcaactatttcctgtcccctgccttccgctaccagccagacccctggaag
ggaagtgcagcaaagggggcaggcatcaccaggaagaagacctttaaggaagtagccaat
gcagtgaagatctctgcctcactcatgggcacggtgatggcgaagcgtgtgaaggcaacc
attctgtatggctctgagactggccgggcccagagctacgcacagcagctgggaagactc
tttcggaaggcgtttgatccccgggtcctgtgcatggatgagtatgatgtggtatcccta
gagcacgaggcactggtgttggtggtgaccagcacatttggcaatggggatcccccggag
aatggagagagctttgcagcagcactcatggaaatgtcaggcccgtacaacagctcccct
aggcctgagcagcacaagagctacaaaatccgattcaacagtgtctcctgctcagaccca
ctggtatcctcttggcggcgcaagaggaaggagtctagcaacacagacagtgcaggagcc
ctgggcaccctcaggttctgtgtgtttgggctgggctcccgagcatacccccacttctgt
gcctttgctcgagcggtggacacaaggctggaggagctgggcggggagcgactactgcag
ctgggccaaggtgatgagctctgtggccaggaggaggctttccgaggctgggcccaggcc
gccttccaggctgcctgtgaaaccttctgtgtgggagaagatgccaaagctgctgcccga
gatatcttcagccccaaacgcagctggaagcgccagaggtaccggctgagtacccaggct
gagagcctgcaattactaccagggctgactcacgtgcacaggcggaagatgttccaggct
acaatcctctctgtggaaaacctacagagcagcaaatccacccgagccacgatcctggtg
cgtctggacaccggaggccaggagggactgcagtaccagccaggggaccacataggtgtg
tgcccacccaaccgtcctggcctagtggaggcactgctgagccgagtggaggaccctccg
ccatccacagaacctgtggctgtggaacaactggagaaaggcagccctggtggccctccc
cccggctgggtacgggaccctcggctacccccatgtacgctgcggcaggctctcacctac
ttcctggacatcacttccccgcctagtcctcgcctccttcgactgctcagcaccctggca
gaagagtccagcgaacagcaggagctagaggctctcagccaggacccccggcgctacgaa
gagtggaagtggttcagctgccccacactgctagaggtgctggagcaatttccttcagtg
gcactgcctgccccgctgatcctcacccagctgcccttgctccagccccggtactactct
gtcagttcagcacccagcgcccacccaggagagatccacctcaccatagctgtgctggct
tacagaacccaggatgggctgggccctctgcactacggcgtctgctccacgtggatgagc
cagctcaaggcgggagatccagtgccctgcttcatcaggggggctccctccttccggctg
ccacctgatcctaacttgccctgcatcctggtgggtccagggactggcattgcacccttc
cggggattctggcaagacagactacacgacattgagatcaaagggctacagcctgccccc
atgactttggtgtttggctgccgatgctcccaactggaccatctctaccgggacgaagta
ctggacgcccagcaacgtggggtgtttggacaagtcctcaccgccttttccagggatcct
ggcagccccaagacctacgtgcaagacctcctgaggacagagctagccgcggaggttcac
cgtgtgctgtgccttgagcaaggacatatgtttgtctgcggcgatgtcactatggcaact
agcgtcctgcaaaccgtgcagcgaattctggcaacagagggcggcatggagctggatgaa
gccggtgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaggacattttcgga
ctcacattgcgcacccaggaggtgacaagccgcatacgcacccagagcttttctttgcag
gagcgacagctgaggggcgcagtgccctggtcctttgacccgcctggcccagaaatacct
ggttcctga
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integrated database retrieval system
