Mus caroli (Ryukyu mouse): 110296314
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Entry
110296314 CDS
T05910
Symbol
Cftr
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal02010
ABC transporters
mcal04024
cAMP signaling pathway
mcal04152
AMPK signaling pathway
mcal04530
Tight junction
mcal04971
Gastric acid secretion
mcal04972
Pancreatic secretion
mcal04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
110296314 (Cftr)
09132 Signal transduction
04024 cAMP signaling pathway
110296314 (Cftr)
04152 AMPK signaling pathway
110296314 (Cftr)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
110296314 (Cftr)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
110296314 (Cftr)
04972 Pancreatic secretion
110296314 (Cftr)
04976 Bile secretion
110296314 (Cftr)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
mcal02000
]
110296314 (Cftr)
Enzymes [BR:
mcal01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
110296314 (Cftr)
Transporters [BR:
mcal02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
110296314 (Cftr)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ABC_membrane
CFTR_R
ABC_tran
AAA_21
SMC_N
AAA_29
T2SSE
DUF87
AAA_16
NTPase_1
nSTAND3
NB-ARC
MMR_HSR1
MeaB
AAA_30
AAA_23
Motif
Other DBs
NCBI-GeneID:
110296314
NCBI-ProteinID:
XP_021020617
Ensembl:
MGP_CAROLIEiJ_G0028123
UniProt:
A0A6P5PVZ0
LinkDB
All DBs
Position
6:13760200..13905758
Genome browser
AA seq
1477 aa
AA seq
DB search
MQKSPLEKAGFISKLFFSWTTPILRKGYRHHLELSDIYQAPSADSADHLSEKLEREWDRE
QASKKNPQLIHALRRCFFWRFIFYGILLYLGEVTKAVQPVLLGRIIASYDPENKVERSIA
IYLGIGLCLLFIVRTLLLHPAIFGLHRIGMQMRTAMFSLIYKKTLKLSSRVLDKISIGQL
VSLLSNNLNKFDEGLALAHFIWIAPLQVTLLMGLLWDLLQFSAFCGLGLLIILVIFQAIL
GKMMVKYRDQRAAKINERLVITSEIIDNIYSVKAYCWESAMEKMIENLREVELKMTRKAA
YMRFFTSSAFFFSGFFVVFLSVLPYTVINGIVLRKIFTTISFCIVLRMSVTRQFPTAVQI
WYDSFGMIRKIQDFLQKQEYKVLEYNLMTTGIVMENVTAYWEEGFGELLEKVQQSNGDRK
HSNDENNVSFSHLCLVGNPVLKNISLNIEKGEMLAITGSTGSGKTSLLMLILGELEASEG
IIKHSGRVSFCSQFSWIMPGTIKENIIFGVSYDEYRYKSVVKACQLQQDITKFAEQDNTV
LGEGGVTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEEQVFESCVCKLMANKTR
ILVTSKMEHLRKADKILILHQGSSYFYGTFSELQSLRPDFSSKLMGYDTFDQFTEERRSS
ILTETLRRFSVDDSSAPWNKPKQSFRQTGELGEKRKNSILNSFSSVRKISIVQKTPLCID
GESDDLQEKRLSLVPDSEQGEAALPRSNMIATGPTFPGRRRQSVLDLMTFTPNSGSSNLQ
RTRTSIRKISLVPQISLNEVDVYSRRLSQDSTLNITEEINEEDLKECFLDDVIKIPPVTT
WNTYLRYFTLHKGLLVVLIWCVLVFLVEVAASLFVLWLLKNNPVNSGNNGTKISNSSYVV
IITSTSFYYIFYIYVGVADTLLALSLFRGLPLVHTLITASKILHRKMLHSILHAPMSTIS
KLKAGGILNRFSKDIAILDDFLPLTIFDFIQLVFIVIGAIIVVSALQPYIFLATVPGLVV
FILLRAYFLHTAQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFRRQTYFETLFHKALNLH
TANWFMYLATLRWFQMRIDMIFVLFFIVVTFISILTTGEGEGTAGIILTLAMNIMSTLQW
AVNSSIDTDSLMRSVSRVFKFIDIQTEESMYTQIMKELPREGSADVLVIKNEHVKKSDIW
PSGGEMVVKDLTVKYMDDGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRMLNIK
GDIEIDGVSWNSVTLQEWRKAFGVITQKVFIFSGTFRQNLDPNGKWKDEEIWKVADEVGL
KSVIEQFPGQLNFTLVDGGYVLSHGHKQLMCLARSVLSKAKIILLDEPSAHLDPITYQVI
RRVLKQAFAGCTVILCEHRIEAMLDCQRFLVIEESNVWQYDSLQALLSEKSIFQQAISSS
EKMRFFQGRHSSKHKPQTTQITALKEETEEEAQETRL
NT seq
4434 nt
NT seq
+upstream
nt +downstream
nt
atgcagaagtcgcctttggagaaagccggctttatctccaaactcttcttcagctggacc
acaccaattttgaggaaagggtacagacaccacttggagttgtcagacatataccaagcc
ccttctgctgattcagctgaccacttatctgaaaaactagaaagagaatgggacagagaa
caagcttcaaaaaagaatccccagcttatccatgcccttcggcgatgctttttctggaga
ttcatcttctatggaattttgctatacctaggggaagtcaccaaggctgtccagcctgtc
ttgctaggaagaatcatagcatcctatgatccagaaaacaaggtggagcgttccattgcc
atttacctaggcataggcttatgccttctcttcattgtcaggacactgcttcttcaccca
gctatttttggccttcatcgcattggaatgcagatgagaacagctatgtttagcttgatc
tataagaagactttaaagttgtcaagccgcgttcttgataaaataagtattggacaactt
gttagtcttctttccaacaacctgaacaaatttgatgaaggacttgccttggcacatttt
atatggattgctcctttacaagtgactcttctgatggggcttctctgggacttgttacag
ttctcagccttctgtggccttggtttactgataatcctggttatttttcaagctatctta
gggaagatgatggtgaagtacagagatcagagagctgcaaagatcaatgaaagactcgtg
atcacatcagaaattattgataatatctattctgttaaggcatattgttgggaatcagcc
atggagaaaatgattgaaaacttgagagaggtggaactgaaaatgacccggaaggcagcc
tacatgaggttcttcactagctctgccttcttcttttcagggttctttgtagtcttttta
tctgtgcttccctacacagtcatcaacggaatcgtcctacgaaaaatattcacaaccatt
tcattctgcattgtcctccgtatgtcggtcacgcggcagttccccactgctgtacagata
tggtatgattcttttggaatgataagaaaaatacaggatttcctgcagaaacaagagtat
aaagtactggagtataacttaatgaccacaggcatagtcatggagaatgtaacagcatat
tgggaggagggatttggggagttactggagaaagtacaacaaagcaatggtgatagaaaa
cattccaatgacgagaacaatgtcagtttcagtcatctctgccttgtgggaaatcctgtg
ctaaaaaacatcagtttgaatatagagaaaggggagatgttggctattactggatctact
ggatcaggaaagacatcactcctgatgttgattttgggagaactggaagcttcagaggga
attattaagcacagtggaagagtttcattctgctctcaattttcttggattatgccgggt
actatcaaagaaaatatcatctttggtgtttcctatgatgagtacagatataagagcgtt
gtcaaagcttgccaactacagcaggacatcaccaagtttgcagaacaagacaacacagtt
cttggagaaggtggagtcacactgagtggaggtcagcgtgcaaggatttctttagcaaga
gcagtatataaagatgctgatttgtacctattagattccccttttggatatctagatgtt
tttactgaagaacaagtatttgaaagctgtgtttgtaaattgatggccaacaaaactagg
attttggttacatctaaaatggaacacttaaggaaagctgacaaaatactaattttgcat
cagggcagcagctatttttatgggacattttctgagctacaaagtctacgtccagacttc
agttcaaaactcatggggtatgatacttttgaccagtttactgaggaaagaagaagttca
attctaactgagaccttacgcaggttctcagtagacgattcctctgccccttggaacaaa
cccaaacagtcatttagacagactggagagttgggagaaaaaaggaagaactctatttta
aattcattcagctctgtaaggaaaatttccattgtgcagaagactccattatgtatcgat
ggagaatctgatgatctccaagaaaagagactgtccctagttccagattctgaacaggga
gaggctgctctgccgcgcagcaacatgattgccactggccccacatttccaggcagaaga
agacagtctgttttggatctgatgacattcacacccaactcaggctccagtaatcttcag
aggaccagaacttctattcgaaaaatctccttagtccctcagataagcttaaatgaagtg
gatgtatattcaaggagattatcgcaagatagcacattgaacatcactgaagaaattaat
gaagaagatttaaaggagtgttttcttgatgatgtgataaagatacccccggtgacaaca
tggaacacatacctacggtatttcactctccataaaggcttactggtagtgctgatctgg
tgcgtgctggtttttctggttgaggtggctgcttctttatttgtgttgtggttgcttaaa
aacaaccctgttaacagtggaaacaatggtactaaaatttccaatagctcctatgttgtg
atcattaccagtaccagtttctattatattttttacatttacgtgggagtggctgacact
ttgcttgccctgagcctcttcagaggtttgccgctggtgcatacgttaatcacagcatca
aaaattttgcacaggaaaatgttacactctattcttcatgcccctatgtcgaccatcagc
aagctgaaagcaggtgggattcttaacagattctccaaagatatagcaattttggatgac
tttctgcctcttaccatatttgacttcattcagttggtgttcattgtgattggagctata
atagtcgtctcggcattacaaccctacatcttcctagcgacggtgccagggctagtagtc
tttatattactgagggcgtacttccttcataccgcacagcagctcaaacaactggaatct
gaaggcaggagtccaattttcacccaccttgtgacaagcttaaaaggactctggacgctt
cgagccttccgacgccagacttactttgaaactctgttccacaaagctctgaatttgcac
actgccaactggtttatgtacctggcaaccttgcgctggttccaaatgagaatagacatg
atttttgtcctcttcttcattgttgttaccttcatctccattttaacaacaggtgaagga
gaaggaacagctggtattattctaactttagctatgaatatcatgagtactttgcagtgg
gctgtgaactcaagcattgatacagatagcttgatgcgttctgtgagcagagtctttaag
tttattgatattcaaacagaagaaagtatgtatacacagataatgaaagaactacctaga
gaaggatcagctgatgttttagtcattaagaatgagcatgtgaagaaaagcgatatctgg
ccctcgggaggcgaaatggttgtcaaagaccttactgtgaaatacatggatgatggaaat
gccgtattagagaacatttctttttcaataagtcctggacagagggtggggctcttagga
agaactggatcaggaaaaagtactttgctttcagcatttttacgaatgttgaacattaaa
ggtgatatagagatcgatggtgtctcatggaattcagtgaccttacaagaatggagaaaa
gctttcggagtgataacacagaaagtatttatcttttctggaacattcagacaaaacctg
gatcccaatggaaaatggaaagatgaagaaatatggaaagttgcagatgaggttggactc
aagtctgtaatagagcagtttcctggacagctcaactttacccttgtggatgggggttat
gtgctaagccacggccataagcaattaatgtgcttggcccgatctgttctcagtaaggcc
aagatcatactgcttgatgagcccagtgcccatctagaccccataacataccaagtaatt
cgacgggttctaaaacaagccttcgctggttgcacagtcatcctctgtgaacacaggata
gaagcaatgttggattgtcagcgatttttggtcatagaagagagcaatgtctggcagtac
gactcccttcaggctcttctgagtgagaagagtatcttccagcaggccattagctcctca
gaaaagatgaggttcttccagggccgccactccagcaagcacaagcctcagactacgcaa
attactgctctgaaagaggagacagaagaagaagctcaagaaacccgtctctag
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integrated database retrieval system
