KEGG   Mus caroli (Ryukyu mouse): 110300173
Entry
110300173         CDS       T05910                                 
Symbol
Prkaca
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal01522  Endocrine resistance
mcal04010  MAPK signaling pathway
mcal04014  Ras signaling pathway
mcal04020  Calcium signaling pathway
mcal04024  cAMP signaling pathway
mcal04062  Chemokine signaling pathway
mcal04081  Hormone signaling
mcal04082  Neuroactive ligand signaling
mcal04114  Oocyte meiosis
mcal04140  Autophagy - animal
mcal04211  Longevity regulating pathway
mcal04213  Longevity regulating pathway - multiple species
mcal04261  Adrenergic signaling in cardiomyocytes
mcal04270  Vascular smooth muscle contraction
mcal04310  Wnt signaling pathway
mcal04340  Hedgehog signaling pathway
mcal04371  Apelin signaling pathway
mcal04530  Tight junction
mcal04540  Gap junction
mcal04611  Platelet activation
mcal04713  Circadian entrainment
mcal04714  Thermogenesis
mcal04720  Long-term potentiation
mcal04723  Retrograde endocannabinoid signaling
mcal04724  Glutamatergic synapse
mcal04725  Cholinergic synapse
mcal04726  Serotonergic synapse
mcal04727  GABAergic synapse
mcal04728  Dopaminergic synapse
mcal04740  Olfactory transduction
mcal04742  Taste transduction
mcal04750  Inflammatory mediator regulation of TRP channels
mcal04910  Insulin signaling pathway
mcal04911  Insulin secretion
mcal04912  GnRH signaling pathway
mcal04913  Ovarian steroidogenesis
mcal04914  Progesterone-mediated oocyte maturation
mcal04915  Estrogen signaling pathway
mcal04916  Melanogenesis
mcal04918  Thyroid hormone synthesis
mcal04919  Thyroid hormone signaling pathway
mcal04921  Oxytocin signaling pathway
mcal04922  Glucagon signaling pathway
mcal04923  Regulation of lipolysis in adipocytes
mcal04924  Renin secretion
mcal04925  Aldosterone synthesis and secretion
mcal04926  Relaxin signaling pathway
mcal04927  Cortisol synthesis and secretion
mcal04928  Parathyroid hormone synthesis, secretion and action
mcal04934  Cushing syndrome
mcal04935  Growth hormone synthesis, secretion and action
mcal04961  Endocrine and other factor-regulated calcium reabsorption
mcal04962  Vasopressin-regulated water reabsorption
mcal04970  Salivary secretion
mcal04971  Gastric acid secretion
mcal04976  Bile secretion
mcal05012  Parkinson disease
mcal05020  Prion disease
mcal05030  Cocaine addiction
mcal05031  Amphetamine addiction
mcal05032  Morphine addiction
mcal05034  Alcoholism
mcal05146  Amoebiasis
mcal05163  Human cytomegalovirus infection
mcal05165  Human papillomavirus infection
mcal05166  Human T-cell leukemia virus 1 infection
mcal05200  Pathways in cancer
mcal05203  Viral carcinogenesis
mcal05205  Proteoglycans in cancer
mcal05207  Chemical carcinogenesis - receptor activation
mcal05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110300173 (Prkaca)
   04014 Ras signaling pathway
    110300173 (Prkaca)
   04310 Wnt signaling pathway
    110300173 (Prkaca)
   04340 Hedgehog signaling pathway
    110300173 (Prkaca)
   04371 Apelin signaling pathway
    110300173 (Prkaca)
   04020 Calcium signaling pathway
    110300173 (Prkaca)
   04024 cAMP signaling pathway
    110300173 (Prkaca)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    110300173 (Prkaca)
   04081 Hormone signaling
    110300173 (Prkaca)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    110300173 (Prkaca)
  09143 Cell growth and death
   04114 Oocyte meiosis
    110300173 (Prkaca)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    110300173 (Prkaca)
   04540 Gap junction
    110300173 (Prkaca)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110300173 (Prkaca)
   04062 Chemokine signaling pathway
    110300173 (Prkaca)
  09152 Endocrine system
   04911 Insulin secretion
    110300173 (Prkaca)
   04910 Insulin signaling pathway
    110300173 (Prkaca)
   04922 Glucagon signaling pathway
    110300173 (Prkaca)
   04923 Regulation of lipolysis in adipocytes
    110300173 (Prkaca)
   04912 GnRH signaling pathway
    110300173 (Prkaca)
   04913 Ovarian steroidogenesis
    110300173 (Prkaca)
   04915 Estrogen signaling pathway
    110300173 (Prkaca)
   04914 Progesterone-mediated oocyte maturation
    110300173 (Prkaca)
   04921 Oxytocin signaling pathway
    110300173 (Prkaca)
   04926 Relaxin signaling pathway
    110300173 (Prkaca)
   04935 Growth hormone synthesis, secretion and action
    110300173 (Prkaca)
   04918 Thyroid hormone synthesis
    110300173 (Prkaca)
   04919 Thyroid hormone signaling pathway
    110300173 (Prkaca)
   04928 Parathyroid hormone synthesis, secretion and action
    110300173 (Prkaca)
   04916 Melanogenesis
    110300173 (Prkaca)
   04924 Renin secretion
    110300173 (Prkaca)
   04925 Aldosterone synthesis and secretion
    110300173 (Prkaca)
   04927 Cortisol synthesis and secretion
    110300173 (Prkaca)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110300173 (Prkaca)
   04270 Vascular smooth muscle contraction
    110300173 (Prkaca)
  09154 Digestive system
   04970 Salivary secretion
    110300173 (Prkaca)
   04971 Gastric acid secretion
    110300173 (Prkaca)
   04976 Bile secretion
    110300173 (Prkaca)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    110300173 (Prkaca)
   04961 Endocrine and other factor-regulated calcium reabsorption
    110300173 (Prkaca)
  09156 Nervous system
   04724 Glutamatergic synapse
    110300173 (Prkaca)
   04727 GABAergic synapse
    110300173 (Prkaca)
   04725 Cholinergic synapse
    110300173 (Prkaca)
   04728 Dopaminergic synapse
    110300173 (Prkaca)
   04726 Serotonergic synapse
    110300173 (Prkaca)
   04720 Long-term potentiation
    110300173 (Prkaca)
   04723 Retrograde endocannabinoid signaling
    110300173 (Prkaca)
  09157 Sensory system
   04740 Olfactory transduction
    110300173 (Prkaca)
   04742 Taste transduction
    110300173 (Prkaca)
   04750 Inflammatory mediator regulation of TRP channels
    110300173 (Prkaca)
  09149 Aging
   04211 Longevity regulating pathway
    110300173 (Prkaca)
   04213 Longevity regulating pathway - multiple species
    110300173 (Prkaca)
  09159 Environmental adaptation
   04713 Circadian entrainment
    110300173 (Prkaca)
   04714 Thermogenesis
    110300173 (Prkaca)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110300173 (Prkaca)
   05205 Proteoglycans in cancer
    110300173 (Prkaca)
   05207 Chemical carcinogenesis - receptor activation
    110300173 (Prkaca)
   05203 Viral carcinogenesis
    110300173 (Prkaca)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    110300173 (Prkaca)
   05163 Human cytomegalovirus infection
    110300173 (Prkaca)
   05165 Human papillomavirus infection
    110300173 (Prkaca)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    110300173 (Prkaca)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    110300173 (Prkaca)
   05020 Prion disease
    110300173 (Prkaca)
  09165 Substance dependence
   05030 Cocaine addiction
    110300173 (Prkaca)
   05031 Amphetamine addiction
    110300173 (Prkaca)
   05032 Morphine addiction
    110300173 (Prkaca)
   05034 Alcoholism
    110300173 (Prkaca)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    110300173 (Prkaca)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    110300173 (Prkaca)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    110300173 (Prkaca)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcal01001]
    110300173 (Prkaca)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mcal03019]
    110300173 (Prkaca)
   03036 Chromosome and associated proteins [BR:mcal03036]
    110300173 (Prkaca)
Enzymes [BR:mcal01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     110300173 (Prkaca)
Protein kinases [BR:mcal01001]
 Serine/threonine kinases: AGC group
  PKA family
   110300173 (Prkaca)
Messenger RNA biogenesis [BR:mcal03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     110300173 (Prkaca)
Chromosome and associated proteins [BR:mcal03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    110300173 (Prkaca)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C Haspin_kinase
Other DBs
NCBI-GeneID: 110300173
NCBI-ProteinID: XP_021025902
Ensembl: MGP_CAROLIEiJ_G0031282
UniProt: A0A6P5Q230
LinkDB
Position
8:75313730..75336866
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVML
VKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgccgccgccaagaagggcagcgagcaggagagcgtgaaagagttccta
gccaaagccaaggaagatttcctgaaaaaatgggagaccccttctcagaacacagcccag
ttggatcagtttgatagaatcaagacccttggcaccggctcctttgggcgagtgatgctg
gtgaagcacaaggagagtgggaaccactacgccatgaagatcttagacaagcagaaggtg
gtgaagctaaagcagatcgagcacactctgaatgagaagcgcatcctgcaggccgtcaac
ttcccgttcctggtcaaacttgaattctccttcaaggacaactcaaacctgtacatggtc
atggagtatgtagctggtggcgagatgttctcccacctacggcggattggaaggttcagc
gagccccatgcccgtttctacgcggcgcagatcgtcctgacctttgagtatctgcactcc
ctggacctcatctaccgggacctgaagcccgagaaccttctcatcgaccagcagggctat
attcaggtgacagacttcggttttgccaagcgtgtgaaaggccgtacttggaccttgtgt
gggacccctgagtacttggcccccgagattatcctgagcaaaggctacaacaaggctgtg
gactggtgggctctcggagtcctcatctacgagatggctgctggttacccgcccttcttc
gctgaccagcctatccagatctatgagaaaatcgtctctgggaaggtgcggttcccatcc
cacttcagctctgacttgaaggacctgctgcggaaccttctgcaggtggatctcaccaag
cgctttgggaacctcaagaacggggtcaatgacatcaagaaccacaagtggtttgccacg
actgactggattgccatctatcagagaaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacgagtaactttgacgactatgaggaggaagagatccgggtctccatc
aatgagaagtgtggcaaggagtttactgagttttag

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