Mus caroli (Ryukyu mouse): 110302481
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Entry
110302481 CDS
T05910
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal04217
Necroptosis
mcal04380
Osteoclast differentiation
mcal04620
Toll-like receptor signaling pathway
mcal04621
NOD-like receptor signaling pathway
mcal04630
JAK-STAT signaling pathway
mcal04658
Th1 and Th2 cell differentiation
mcal04659
Th17 cell differentiation
mcal05145
Toxoplasmosis
mcal05160
Hepatitis C
mcal05161
Hepatitis B
mcal05162
Measles
mcal05164
Influenza A
mcal05165
Human papillomavirus infection
mcal05167
Kaposi sarcoma-associated herpesvirus infection
mcal05168
Herpes simplex virus 1 infection
mcal05169
Epstein-Barr virus infection
mcal05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
110302481 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
110302481 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
110302481 (Tyk2)
04621 NOD-like receptor signaling pathway
110302481 (Tyk2)
04658 Th1 and Th2 cell differentiation
110302481 (Tyk2)
04659 Th17 cell differentiation
110302481 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
110302481 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
110302481 (Tyk2)
05160 Hepatitis C
110302481 (Tyk2)
05171 Coronavirus disease - COVID-19
110302481 (Tyk2)
05164 Influenza A
110302481 (Tyk2)
05162 Measles
110302481 (Tyk2)
05168 Herpes simplex virus 1 infection
110302481 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
110302481 (Tyk2)
05169 Epstein-Barr virus infection
110302481 (Tyk2)
05165 Human papillomavirus infection
110302481 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110302481 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcal01001
]
110302481 (Tyk2)
Enzymes [BR:
mcal01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
110302481 (Tyk2)
Protein kinases [BR:
mcal01001
]
Non-receptor tyrosine kinases
JAK family [OT]
110302481 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
110302481
NCBI-ProteinID:
XP_021028934
Ensembl:
MGP_CAROLIEiJ_G0031861
UniProt:
A0A6P5QLA0
LinkDB
All DBs
Position
9:complement(17114409..17141455)
Genome browser
AA seq
1184 aa
AA seq
DB search
MVGTMPLCGRRAILEDSKADGTEAQPLVPTGCLMVLLHWPGPEGGEPWVTFSQTSLTAEE
VCIHIAHKVGITPPCLNLFALYNAQAKVWLPPNHILDTSQDMSLYFRMRFYFRNWHGMNP
QEPAVYRCGFPGAETSSDRAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIH
HFKNESLGMAFLHLCHLALSRGIPLEEMAREISFKNCIPRSFRQHIRQHNVLTRLRLRRV
FRRFLRAFRPGHLSQQVVMVKYLATLERLAPRFGSERIPVCHLEVLAQPERDPCYIQNSG
QTVGDPGPELPSGPPTHEVLVTGTGGIQWHPLQTQESERGNSRGNPHGSRSEKKPKAPEA
GEHLTESPQEPPWTYFCDFQDISHVVLKERRVHIHLQDNKCLLLCLCSQAEALSFVALVD
GYFRLTADSSHYLCHEVAPPRLVTSIQNGIHGPLMDPFVQAKLWPEDGLYLIQWSTSHLH
RLILTVAHRNPALSNGPRGLRLRKFPITQQPGAFVLDGWGRSFDSLGDLRLALQGCSLRA
GDDCFPLHHCCLPRPREISNLVIMRGSRAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTR
TNVYEGLLRVGGPDEGKVDNGCPPEPGGTSGQQLRVVLKVLDPSHHDIALAFYETASLMS
QVSHMHLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGQVPMTWKMAVAQQLASALS
YLEDKNLVHGNVCGRNILLARLGLEEGTNPFIKLSDPGVGQGALSREERVERIPWTAPEC
LSGGTSSLGTATDMWGFGATLLEICFDGEAPLQGRGPSEKERFYTKKHQLPEPSCPELAT
LTRQCLTYEPAQRPSFRTILRDLTRLQPQNLVGTSAVNSDSPASDPTVFHKRYLKKIRDL
GEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCSPQLRSGWQREIEILRTLYHEHIVKYK
GCCEDQGEKSVQLVMEYVPLGSLRDYLPRHCVGLAQLLLFAQQICEGMAYLHAQHYIHRD
LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASD
VWSFGVTLYELLTYCDSNQSPHTKFTELIGHTQGQMTVLRLTELLERGERLPRPDRCPCE
IYHLMKNCWETEASFRPTFQNLVPILQTAQEKYQGQVPSVFSVC
NT seq
3555 nt
NT seq
+upstream
nt +downstream
nt
atggtggggaccatgcctttgtgtgggcggagagccatcttggaagacagcaaggcagat
ggcacagaagctcagcccctggtgcccacaggatgcttgatggtgctactgcactggcct
gggcctgagggcggggagccctgggtcaccttcagccagacatctctgactgcagaggag
gtctgcatccacatcgcacacaaagtcggcatcactccaccctgcttgaatctcttcgca
ctctacaatgcacaggccaaggtctggctgcccccaaaccatattctggatacatcccaa
gacatgagcctctattttcgaatgaggttttacttccggaactggcatggcatgaatccc
caggagccagctgtataccgatgtggtttcccaggggcagagacttcctcagaccgggca
gagcaaggtgtacagctcttggactctgcctcgtttgaatacctttttgagcagggaaaa
catgagttcatgaatgatgtggtgtctctgcgggacctgtctagcgaggaggagatccac
cactttaagaatgagagcttaggcatggccttcctgcacctgtgtcaccttgctctcagc
cgcggcatccccctggaggagatggccagagaaatcagcttcaagaactgcatccctcgt
tccttccgacagcacattcggcagcacaatgtgctcacacgcctgcgtctccgcagggtc
ttccgccgcttcctgcgggccttccggcctggccacctctcccagcaggttgtgatggtt
aagtacttggccaccctggagcggctggctcctcgctttggctcagagcgcatacctgtg
tgtcatctggaggtcctggcacagcctgagagggacccctgctacatccagaacagtggg
cagaccgttggggacccaggcccagagctgccttccggtcctcccacccacgaggtactg
gtgacaggcaccggaggtatccagtggcatccactacagacccaggaatctgagagaggt
aacagcagagggaatccccatggcagccggtcggagaagaaacccaaagcccccgaggct
ggagagcaccttacagagagccctcaggaaccaccttggacctacttctgtgacttccag
gacatttcccacgtggtgctaaaggagcgccgcgtgcacatccacctccaagacaacaag
tgcttgttgctgtgcctctgttcccaggctgaggccctgtcctttgtggcccttgtcgat
ggctatttccgcttgactgctgactccagccactacctgtgccatgaggtggcacccccg
aggctggtgactagcatccagaacggcatccatggccccctgatggatccgtttgtacag
gccaagctgtggccagaggacggcctctacctgattcagtggagcaccagccacctgcac
cgcctgatccttaccgtggcccatcgaaacccggctctcagtaatggccctaggggcctg
cgcctgcgaaagttccccatcacacagcagcctggagcctttgtgctggatggctggggc
cgctcctttgacagcttgggggaccttcgactcgccttgcagggctgctcattgcgggcg
ggtgatgactgtttccccctgcaccactgctgcctgccccggccaagagaaatctccaac
ctcgtcatcatgcgggggtctagggcccacacccggcctctcaacctcagtcagctcagc
ttccacagggttcaccaggatgaaatcacccagctgtcccacttgggccaaggcacaagg
accaatgtgtatgagggccttctaagagtgggaggccccgatgagggcaaagtggacaat
ggatgtccccctgagcctggtgggaccagtgggcagcagcttcgagtggtgctcaaagtt
ctcgaccccagtcaccatgatattgccttggccttctatgagactgctagcctcatgagc
caggtgtcacacatgcacctggctttcctgcatggtgtttgcgtgcgtggctcagagaat
atcattgtgacagaattcgtagaacatggtcccttggatgtgtggttacggcgacagagg
ggccaagtgcccatgacctggaagatggccgtggctcagcagctggccagcgccctcagc
tacctggaggacaagaatctggttcacgggaatgtatgtggccggaacatcctgctggct
cgcctggggctggaggagggtaccaacccgttcatcaagctgagtgatcctggtgtgggc
caaggtgccctctccagggaagagagggtggagcgcatcccctggacagctcccgagtgc
ctgtctggagggaccagtagcttgggtactgccacggacatgtggggctttggtgccacc
cttcttgagatctgctttgatggggaggcacccctgcagggtcgtggtccctctgagaaa
gaacggttctacacaaagaaacatcagctgccagaaccctcatgcccagagctggccaca
ctcacccgccagtgcctgacctatgaaccagcacagcggccatccttccgcaccattttg
cgggacctcacaagactgcagccacagaatctagtcggcacttcggctgtgaactcagac
tcaccagcatcagaccccactgttttccacaagcgctatttgaaaaagatccgggatttg
ggcgagggtcactttggcaaggtcagcctgtactgctacgatccaaccaatgacggcact
ggtgagatggtggcggtcaaggccctgaaagaggggtgcagtccccagctccgctcaggc
tggcagcgggagatcgagatcctgcggacactgtaccacgaacatatcgtcaagtataaa
ggctgctgtgaggaccaaggagagaagtctgtacagctggtcatggagtacgtccctctg
ggcagcctccgagactacctgccaaggcactgcgtagggctggcacagctcctgctgttt
gcccagcagatctgcgagggcatggcctacctgcacgctcagcactacatacaccgagac
cttgcggcgcgcaacgtgctgctggacaacgacaggctggtcaagattggagactttggc
ctagccaaggctgtacctgaaggccacgagtactaccgagtgcgcgaggacggggacagc
ccagtgttctggtatgccccagaatgcctgaaggagtgcaaattttactatgcatctgat
gtctggtccttcggagtaaccctttatgagttgttgacatactgtgactctaaccagagt
ccccatacgaaattcaccgagctcatcggccatacccagggccagatgactgtgctgagg
ctcacagagctgctagaacgaggagagaggctgcctcggcctgacaggtgtccctgtgag
atctatcacctcatgaagaactgctgggagacagaggcctctttccggcccaccttccag
aatcttgtgcctatcctccagacagcgcaggagaagtaccaaggtcaggtgccttccgtg
ttcagcgtgtgctga
DBGET
integrated database retrieval system
