Mus caroli (Ryukyu mouse): 110302935
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Entry
110302935 CDS
T05910
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal00310
Lysine degradation
mcal01100
Metabolic pathways
mcal05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
110302935 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
110302935 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mcal03036
]
110302935 (Dot1l)
Enzymes [BR:
mcal01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
110302935 (Dot1l)
Chromosome and associated proteins [BR:
mcal03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
110302935 (Dot1l)
HMT complexes
Dot1-containing complex
110302935 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
110302935
NCBI-ProteinID:
XP_021029412
Ensembl:
MGP_CAROLIEiJ_G0015600
UniProt:
A0A6P5Q9I7
LinkDB
All DBs
Position
10:74755551..74796233
Genome browser
AA seq
1736 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVP
ESKAAATEAPADSGAEEEKSGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAAS
AERKSKKSQSTLDLLHSPPPAPPSASPQDAYRAPHSPFYQLPPSTQLHSPNPLLVAPTPP
ALQKLLESFRIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFGHCQAQKEE
IRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRA
RCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSC
VPPDDALSLHLRGKSALGRELEADAGRLRLELDCAKISLPHLSSMSPELSMNGHAASYEL
CNAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLR
RHLSQDHTGASKAATSEPHPRPEHAKESSLPYQSPGLSNSMKLSPQDPPLASPATSPLTS
EKGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS
PVPQPRDSSATLEKQIGASAHGAGGAGAGSRSLAVAPTGFYAGSVAISGALASSPAPLAS
GMESAVFDESSGPSSLFATMGSRSTPPQHPPLLSQSRNSGPASPAHQLTASPRLSVTTQG
SLPDTSKGELPSDPAFSDPESEAKRRIVFSISVGASSKQSPSTRHSPLTSGTRGDCVQSH
GQDSRKRSRRKRASAGTPSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLE
ITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSAR
IERKIATISLESKSPPKTLENGGGLVGRKSAPSSEPINSSKWKSTFSPISDLGLAKAVDS
PLQAGSALSHSPLFSFRPSLEEPAAEAKLPTHPRKSFAGSLGAAEGPSPGTNPPNGLAFS
GGLAADLGLHSFNDGASLSHKGPDVTGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGG
LKGEGNANKESGENLPLCGPSDKASLPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGL
LGGPGLVTVASSAGSATPTAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLF
STVPAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFTHAVPSASAHPFGAGVGSG
AVCSSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPP
PPNVALPPPPALLASNPEPVLLQSLASLPANNAFLPPSSAASLQPANASLSVKLASLPHK
VSRPSFTVHHQPLPRLALAQAAPAAPQASTSGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5211 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgcctgtgggcgccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccatgatgctgctcatgagattattgagact
atccggtgggtctgcgaggaaatcccagatctcaagctggccatggagaactatgtcctg
atcgactacgacaccaaaagttttgaaagcatgcagcggctgtgtgacaaatacaaccgg
gccatcgacagcatccaccagctgtggaagggcactacacagcccatgaagctgaatact
cggccatccaatggactcctgcggcacatcctgcagcaggtatataaccactctgtcact
gacccggagaagcttaacaactacgagcccttctcccctgaggtttatggggagacctcc
tttgacctggtggcccagatgattgatgagatcaagatgacagaggatgacctgtttgtc
gacctgggcagtggtgtggggcaggttgtccttcaggttgctgcggccaccaactgcaaa
catcactacggagtggagaaagcggacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcagaggaatggagggaacggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgattcgcaaacatg
aaggaaggcggcagaattgtatcctcaaagccctttgcccctctgaacttcaggatcaac
agcaggaacttgagtgacattggcaccatcatgcgtgtggtggagctgtcgcccctgaag
ggctctgtgtcgtggactggcaagcctgtctcctactacctgcacaccattgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggagcaggaggca
gctaggcgaaggcagcagcgagagaacaagagcaatgcgaccacgcccaccaaagtccct
gagagcaaagcagctgccactgaggcccccgcggattctggtgctgaggaagaaaaatca
ggtgtggctactgtcaaaaagccatctccctccaaagcccggaagaagaaactgaacaag
aaagggagaaagatggctggccggaaacgtgggcggcccaagaaaatgagtgctgccagt
gccgagcgcaagtctaagaagagccaaagcacactggatctcctgcactctccgccccca
gccccaccctcagcctcaccccaggatgcatacagggcacctcacagcccattctaccag
ctacctccgagcacgcagctgcactcacccaacccactgctagtggcacccaccccacct
gcgctgcagaagcttttagaatccttcagaatccagtacctgcagttcctggcttataca
aagaccccgcagtacaaggctaacctacagcagcttctggaccaggagaaggagaagaac
acacagctcctgggcacagcccagcagctcttcggccattgccaggcccaaaaggaagag
atccgcaggctgttccagcagaagctggatgagttgggcgtgaaggcactgacctacaat
gacctgattcaggcccagaaggaaatctctgcccacaaccagcagctgcgggaacagtcg
gaacagctggagaaggacaacagcgagcttcggagccagagcctgcggctgctcagggcc
cggtgcgaggagctgaggcttgactggtccacactgtccctggagaacctgcggaaagag
aagcaggccctgcggagccagatctcagagaagcagcggcactgcctggagctgcagatc
agcatcgtggagctcgagaagacccagcgccagcaggagctcctgcagttaaagtcctgt
gtaccaccagatgatgctctgtctttgcatctgcgcggcaagagtgccctgggccgagag
ctggaggctgacgctgggcgcttacgccttgagctggactgtgccaagatctccctgcca
cacctcagcagcatgagccctgagctgtccatgaacggccatgctgccagctatgagctc
tgcaatgcagctagtcggccatcatccaagcagaacacaccccagtacctggcctctccc
ttggaccaggaggtcgtaccttgcacccctagccacagtggccggcctcggctagaaaag
ctgtctggcctggctttgcctgattacacccggttgtcacctgccaagattgtgttgagg
cggcacctgagccaggaccacactggggctagcaaagcagctaccagtgagccacaccct
cggccagagcacgccaaggagagcagccttccctaccagagccctggcttgtccaacagc
atgaagctcagcccccaggatccaccgctggcctccccggcgacctcacccctcacctcc
gagaagggtagtgagaagggtgtgaaggagcgtgcctacagcagccacggggagaccatc
accagcctacctgttagcattccactcagcacggtgcagcccaacaagctgcccgtcagc
atcccactggccagcgtggtgctgcccagccgtgctgagagggcgaggagcactcccagc
cctgtgccacagccccgggactcttcagccacacttgagaagcagattggtgcttctgcc
catggtgcagggggtgctggagcaggaagcaggagcctcgctgtggcgcccacaggtttc
tatgctggttcggtggccatcagtggggccctggccagcagcccagcacctctggcctct
ggaatggaatctgctgtttttgatgaatcctctggccccagcagcctctttgccaccatg
gggtctcgcagcacaccaccacaacacccacctctcctgtcgcagtcccgcaactcgggt
cctgcctctcctgcccaccaactcacagccagtccccgcctgagtgtgaccactcagggc
tcgctgccagacaccagcaaaggggaactgccttctgatcctgccttctcagacccagag
agcgaagcaaagaggaggattgtgttcagcatttcagttggtgccagctccaagcagtca
ccttccaccaggcatagccccttgacttctggcacccgaggggactgtgtgcagagccac
ggacaagacagtcgtaagcgcagcagaaggaagcgtgcatcagctggaacacctagcctc
agcacgggtgtgtcccctaagcgccgggctctgccaactgttgctggcctctttacacag
tcctcggggtctcctcttaatctcaactccatggtcagcaacatcaaccagccactggag
atcacagccatctcatcccctgagagctccctgaagagctcccccaccccctaccaggac
catgaccagcctccggtgctcaggaaggagcggcctctaggaccaactaatggggcccac
tactcgccactgacctcagatgaggagccaggctctgaggacgagcccagcagtgcccga
attgagagaaaaattgcaacaatctctttagaaagcaaatctcccccgaagacactggaa
aatggtggtggcttggtgggaaggaagtcagccccttcgagtgagcctatcaacagcagc
aaatggaagtccaccttctctcctatctctgacctcggcttggccaaggctgtggacagt
ccgctacaggctggctctgccctgagccacagccccctgttctctttccggccgtccctg
gaggagcctgctgctgaggccaagctccccactcacccaaggaaaagctttgcgggctct
ctgggtgcagccgaggggccaagccctggcaccaaccctcccaacggcctggccttcagt
gggggccttgctgcagacctcggtttacacagcttcaatgacggtgcttccctctcccac
aagggccctgatgtgactggcctgagtgcctccctgagcttcccgtcccagaggggcaag
gacagtaccacagaggccaaccccttcctcagcaggcggcagcctgagggcctgggtggc
ttgaagggtgagggcaacgcaaacaaggagtcaggagagaacctgcccctgtgcgggccc
tcggacaaggcctcactgccacatggcagcagggccagcaaaggccgtgaccgtgagctg
gacttcaagggcggccacaacctcttcatctctgctgcagccgtgcctccaggtggcctc
cttggtggccctggtcttgtaactgtggcttcttctgcgggcagtgcaacacccactgcc
caggctccccggcctttcctgagcacctttgcccccgggccccagtttactctgggcccc
atgtccctgcaggccaacctgggctctgtggccggctcctctgtgctgcagtccttgttc
agcactgtgccagctgctgcaggcctggtgcatgtgtcgtccactgcgacccgactgacc
aactcacacaccatgggcagcttctcttctggggtggccggcggaaccgttggaggtgtc
tttacccacgcggtgccctccgcctctgctcacccgtttggagctggtgtcggcagcggg
gctgtgtgtagcagtgccacgctgggcctgagcccgctgcaggcggcggccagcacctcg
gcttcttcctttcaggccgcggcttcggtcgagactcggccgccccctccacctccccta
cttcctcctcagcatctaggccggccccctgcggggccacctgtcctccatgcaccccct
cctcctaacgtcgccttgcctcctccgcctgcgctgctggcttctaaccctgagccagtg
cttctgcagagcctggcctccctcccagctaacaacgctttcttacccccctcctctgcc
gcctctctgcagcctgctaatgcctctctatctgtcaagctcgcctccctcccacacaag
gtctcccgcccctccttcacggtgcaccaccagcccctgccccggctggccctggcgcag
gccgcgcccgccgccccacaggccagcacctcggggccatctgctgtgtgggtttccctt
ggcatgccgcctccttatgccgcgcacctttcgggggttaagcctcgataa
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