Mus caroli (Ryukyu mouse): 110304558
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Entry
110304558 CDS
T05910
Symbol
Top2a
Name
(RefSeq) LOW QUALITY PROTEIN: DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
110304558 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mcal03032
]
110304558 (Top2a)
03036 Chromosome and associated proteins [BR:
mcal03036
]
110304558 (Top2a)
Enzymes [BR:
mcal01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
110304558 (Top2a)
DNA replication proteins [BR:
mcal03032
]
Eukaryotic type
DNA Topoisomerases
110304558 (Top2a)
Chromosome and associated proteins [BR:
mcal03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
110304558 (Top2a)
Centrosome formation proteins
Centriole proteins
110304558 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
110304558
NCBI-ProteinID:
XP_021031614
UniProt:
A0A6P5QL66
LinkDB
All DBs
Position
11:complement(94912587..94945441)
Genome browser
AA seq
1675 aa
AA seq
DB search
MELSPLQPVNENMLMNKKKNEDGKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQM
WVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIKVTIDPENNVISIWNN
GKGIPVVEHKVEKIYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET
ASREYKKMFKQTWMDNMGRAGDMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMVR
RAYDIAGSTKDVKVFLNGNSLPVKGFRSYVDLYLKDKVDETGNALKVIHEQVNPRWEVCL
TMSERGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMW
IFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQI
QLNKKCSAVKHTKIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKY
GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD
QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSLPEFEEWKSS
TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDR
KEWLTNFMEDRRQRKLLGLPEDYLYGQSTSYLTYNDFINKELILFSNSDNERSIPSMVDG
LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL
NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLRFLYDDNQRVEPEWY
IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEE
LASNQYVINGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPSLITDYREYH
TDTTVKFVIKMTEEKLAEAERVGLHKVFKLQSSLTCNSMVLFDHVGCLKKYDTVLDILRD
FFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRG
YDSDPVKAWKEAQQKVPDEEENEESDTETSTSDSAAEAGPTFNYLLDMPLWYLTKEKKDE
LCKQRNEKEQELNTLKQKSPSDLWKEDLAVFIEELEVVEAKEKQDEQVGLPGKAGKGKGK
KAQMCADVLPSPRGKRVIPQVTVEMKAEAEKKIRRKIKSENVEGTPAEDGVETGSLRQRI
EKKQKREPGAKKQTTLPFKPIKKGKKKNPWSDSESDMSSNESNFDVPPREKEQRSAAAKA
KFTVDLDSHEDFSGADEKDEDEDFFPLDATPPKTKIPPKNTKKALKAQKSSMFADLERDV
KDSVPASSGVPAASATDFPAETEQSKPSSKKTVGVKRTATKKKKQKREPGTIAKKQSTLP
FKPIKKXKKKNPWSDSESGMNSNESNFDVPPXEKEPRIAAAKAKFTVNLDSDEDFXSLDK
KDENEDFLPLDATPPKSTPPPKDTKKALKPQKSCMLVDLESGVKDSMXHAVDFXAETEQL
KPSSKDCGSEKTTKSQSLISTAGGTKKRAAQKGTKSDLTFSDHVSEKSAPAKTKNRSKRK
PSSSDSSDSDFEKAISKGAKSKKPKGEEQVFHVDLEDTVAPQAKSGXARNPIKYL
NT seq
5028 nt
NT seq
+upstream
nt +downstream
nt
atggagttgtcaccgctgcagcctgtaaatgaaaatatgctaatgaacaaaaagaagaat
gaagatggcaagaaaagattgtctattgaaagaatctatcagaaaaaaacacaactggaa
catatcctactccgcccagatacctacattggctctgtggagttagtgacccagcaaatg
tgggtttacgatgaagatgttggcattaactacagggaagtcacttttgttcctggtttg
tataaaatctttgatgagattctagttaatgctgctgataacaaacaaagggacccaaaa
atgtcttgtattaaagtcacaattgatccagaaaataatgtaattagcatctggaataat
gggaaaggaatccctgttgttgaacacaaagttgagaaaatatatgtcccggctctcata
tttggacaactcctgacctccagtaactatgacgacgatgagaagaaagtgacaggtggt
cgaaatggctatggagctaaactgtgtaacatattcagcaccaaatttactgtggaaaca
gccagtagagagtacaagaaaatgttcaaacagacatggatggataacatggggagagct
ggtgacatggaactcaagccctttagtggagaagattatacatgcatcaccttccagcct
gacttatctaagtttaaaatgcaaagcctggacaaagatattgttgcactgatggtcaga
agagcatatgatatcgctggctccactaaagatgtcaaagtctttcttaatggaaatagt
ctgccagtgaaagggttccgcagttacgtggatttgtatttgaaggataaggtagatgaa
actgggaacgcactgaaggtgatccatgagcaggtcaatccccggtgggaagtgtgcttg
acaatgagcgagagaggcttccagcagattagcttcgtcaacagcattgcgacttctaag
ggcggcagacatgttgattacgtagctgatcagattgtgagcaaactcgttgatgtggtg
aaaaagaagaacaagggcggggttgcagtgaaggctcatcaggtgaaaaatcacatgtgg
atttttgtaaatgccttaatcgaaaacccaacctttgactctcaaacaaaagaaaacatg
actttacaagccaagagctttggatcaacatgtcaattaagtgagaagttcatcaaagct
gcaattggttgtggtattgtcgaaagcatactaaactgggtgaagtttaaggctcaaatc
caactgaacaagaagtgttcagctgtaaaacataccaaaatcaagggaatccccaaactt
gatgatgccaatgatgcagggagccgaaactctactgaatgcacacttatcctgactgag
ggagactcagcaaaaactctggccgtttcaggccttggagtggttggaagagacaaatat
ggggtgttccctcttagaggaaagatactcaatgtgcgagaagcctctcataaacagatc
atggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaaaac
tatgaagatgaagattcactgaaaacgcttcgttacgggaagatcatgattatgacagat
caggaccaagatggttctcacatcaaaggcttgctgatcaattttatccatcacaattgg
ccatctcttctgcgacatcgttttctagaagaatttatcactcccattgtaaaggtgtcc
aaaaataagcaagaaatagcattctatagtcttcccgagtttgaagaatggaaaagttca
actccaaatcacaaaaaatggaaagtcaaatactacaaaggtttgggcaccagcacatca
aaggaagctaaggaatattttgcagatatgaagcgacatcgtattcaattcaaatactct
ggccctgaagatgatgctgcgatcagcctggcctttagtaaaaaacaagttgatgatcga
aaggaatggttaactaattttatggaagacagaagacagcggaagttacttggccttcct
gaggattatttgtatggacaaagcacttcgtacctcacctataatgacttcataaacaag
gaactcatcctcttctccaactctgataacgaaaggtctatcccatccatggtagacggt
ttgaaaccaggtcagagaaaggttttgtttacttgtttcaaacggaatgacaagcgagaa
gtgaaggttgcccagttagctgggtcagtggccgaaatgtcctcttatcaccatggtgag
atgtcactgatgatgaccattatcaatttggctcagaattttgtgggcagcaataatttg
aaccttttacagcccatcggtcagtttggaaccaggctgcatggtggcaaggactcagct
agtcctaggtacatctttacaatgctcagccctttggctcggttgttgtttcctccaaaa
gatgatcacacattacggtttctatatgatgacaaccaacgcgttgagcctgaatggtac
attcctataatacccatggtgctgataaatggtgctgagggaattggtactgggtggtcc
tgcaaaatccccaactttgatgtgcgtgaagttgtgaataatatcagacggcttctggat
ggagaggagcccctgcccatgctcccaagttataagaatttcaaaggtactattgaagaa
ctggcttcaaatcagtatgtgattaatggagaagtagctattctggactctacaaccatt
gagatctcagagcttcccatccgaacatggactcagacatataaagaacaggttctagaa
cccatgttgaatggcactgagaagacaccctctctaataacagactatagggaataccat
acagataccactgtgaagtttgtcataaagatgactgaagaaaaattggcagaggcagag
agagtcggcctacacaaagtcttcaaactccagtctagtctcacttgcaactctatggtg
ctttttgaccatgtaggttgcttaaagaaatatgacactgtgttggatattctaagagac
ttctttgagctcaggcttaaatattatggattaagaaaagaatggcttctaggaatgctt
ggtgcagaatcttctaaactgaataatcaagctcgctttatattagagaaaatagatggc
aaaatagtcattgaaaataaacctaaaaaagaattaattaaagttctgattcagagagga
tacgattctgaccctgtgaaagcctggaaagaagctcagcagaaggttccagatgaagaa
gaaaatgaagaaagtgacactgaaaccagcaccagtgactctgcagcagaggctggcccg
accttcaactaccttctcgacatgcccctgtggtatctgaccaaggagaagaaggacgag
ctgtgcaaacaaagaaacgagaaggaacaagagctcaacacgttaaagcaaaagagtcca
tcagatctgtggaaggaagatctggctgtttttattgaagaactggaggttgtcgaagcc
aaggaaaaacaggatgaacaagtaggccttcctggaaaggcggggaaaggaaaggggaag
aaagcacagatgtgtgctgacgtcttgccttctcctcggggaaaaagagtcatcccccaa
gtgactgtagagatgaaagctgaggcagagaagaaaattaggaggaaaattaagagtgaa
aacgttgagggtacccctgctgaggatggtgtggaaacaggaagcctccggcaacgaata
gagaagaagcagaagagagagccaggtgcaaagaagcaaacgacattgccatttaagcct
atcaaaaaagggaaaaagaaaaacccctggtctgattctgagtcagatatgagcagtaat
gaaagtaattttgatgtccctcctcgagaaaaagagcaaagaagtgctgcagcaaaagcc
aaattcacagtggatttagactcccatgaagatttctcaggtgcggatgaaaaggatgag
gatgaagatttcttcccattagatgctactccacctaagaccaaaatcccccccaaaaat
actaaaaaagcactgaaggcccagaaaagctccatgtttgctgatcttgaaagagatgtt
aaggacagtgtgccagcttcttcaggcgttcctgctgcttctgctactgacttcccagcg
gaaactgaacagtcaaagccatcctccaaaaagaccgtgggagtgaagaggacagcaacc
aaaaagaagaagcagaagagagagccaggtaccatagcaaagaagcaatctacattgcca
tttaagcctatcaaaaaatgaaaaaagaaaaacccctggtctgattctgagtcaggtatg
aacagtaatgaaagtaattttgatgtccctccttgagaaaaagagccaagaattgctgca
gcaaaagccaaattcacagtgaatttagactctgatgaagatttttgaagtttggataaa
aaggatgagaatgaagatttccttccattagatgctactccacctaagtccacccccccc
ccaaaagatactaaaaaggctctgaagccacagaaaagctgcatgttggttgatcttgaa
agtggtgttaaggatagtatgnctcatgctgttgacttctgagctgaaactgaacagtta
aagccatcctccaaagactgtgggagtgaaaagacaacaaaaagccagtctttaatctcc
actgctggtggtaccaaaaagagagctgcgcaaaagggaaccaaatcagatttaaccttc
agtgatcatgtctctgaaaagtctgctcctgccaaaaccaagaaccgtagcaagaggaag
ccatcttcttctgatagttctgactctgattttgagaaagcaatttctaaaggtgcaaag
agcaagaagcctaagggagaggaacaggttttccatgtggacttagaagacactgtggct
cctcaagccaaatctggatgagcaaggaacccaattaagtacctgtga
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integrated database retrieval system
