Mus caroli (Ryukyu mouse): 110309267 Help Entry 110309267         CDS       T05910                                  Symbol Adcy4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal00230   Purine metabolism mcal01100   Metabolic pathways mcal01522   Endocrine resistance mcal04015   Rap1 signaling pathway mcal04020   Calcium signaling pathway mcal04022   cGMP-PKG signaling pathway mcal04024   cAMP signaling pathway mcal04062   Chemokine signaling pathway mcal04072   Phospholipase D signaling pathway mcal04081   Hormone signaling mcal04082   Neuroactive ligand signaling mcal04114   Oocyte meiosis mcal04211   Longevity regulating pathway mcal04213   Longevity regulating pathway - multiple species mcal04261   Adrenergic signaling in cardiomyocytes mcal04270   Vascular smooth muscle contraction mcal04371   Apelin signaling pathway mcal04540   Gap junction mcal04611   Platelet activation mcal04713   Circadian entrainment mcal04714   Thermogenesis mcal04723   Retrograde endocannabinoid signaling mcal04724   Glutamatergic synapse mcal04725   Cholinergic synapse mcal04727   GABAergic synapse mcal04742   Taste transduction mcal04750   Inflammatory mediator regulation of TRP channels mcal04911   Insulin secretion mcal04912   GnRH signaling pathway mcal04913   Ovarian steroidogenesis mcal04914   Progesterone-mediated oocyte maturation mcal04915   Estrogen signaling pathway mcal04916   Melanogenesis mcal04918   Thyroid hormone synthesis mcal04921   Oxytocin signaling pathway mcal04923   Regulation of lipolysis in adipocytes mcal04925   Aldosterone synthesis and secretion mcal04926   Relaxin signaling pathway mcal04927   Cortisol synthesis and secretion mcal04928   Parathyroid hormone synthesis, secretion and action mcal04934   Cushing syndrome mcal04935   Growth hormone synthesis, secretion and action mcal04970   Salivary secretion mcal04971   Gastric acid secretion mcal04972   Pancreatic secretion mcal04976   Bile secretion mcal05032   Morphine addiction mcal05163   Human cytomegalovirus infection mcal05166   Human T-cell leukemia virus 1 infection mcal05200   Pathways in cancer mcal05207   Chemical carcinogenesis - receptor activation mcal05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mcal00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     110309267 (Adcy4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     110309267 (Adcy4)    04371 Apelin signaling pathway     110309267 (Adcy4)    04020 Calcium signaling pathway     110309267 (Adcy4)    04072 Phospholipase D signaling pathway     110309267 (Adcy4)    04024 cAMP signaling pathway     110309267 (Adcy4)    04022 cGMP-PKG signaling pathway     110309267 (Adcy4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     110309267 (Adcy4)    04081 Hormone signaling     110309267 (Adcy4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     110309267 (Adcy4)   09144 Cellular community - eukaryotes    04540 Gap junction     110309267 (Adcy4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     110309267 (Adcy4)    04062 Chemokine signaling pathway     110309267 (Adcy4)   09152 Endocrine system    04911 Insulin secretion     110309267 (Adcy4)    04923 Regulation of lipolysis in adipocytes     110309267 (Adcy4)    04912 GnRH signaling pathway     110309267 (Adcy4)    04913 Ovarian steroidogenesis     110309267 (Adcy4)    04915 Estrogen signaling pathway     110309267 (Adcy4)    04914 Progesterone-mediated oocyte maturation     110309267 (Adcy4)    04921 Oxytocin signaling pathway     110309267 (Adcy4)    04926 Relaxin signaling pathway     110309267 (Adcy4)    04935 Growth hormone synthesis, secretion and action     110309267 (Adcy4)    04918 Thyroid hormone synthesis     110309267 (Adcy4)    04928 Parathyroid hormone synthesis, secretion and action     110309267 (Adcy4)    04916 Melanogenesis     110309267 (Adcy4)    04925 Aldosterone synthesis and secretion     110309267 (Adcy4)    04927 Cortisol synthesis and secretion     110309267 (Adcy4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     110309267 (Adcy4)    04270 Vascular smooth muscle contraction     110309267 (Adcy4)   09154 Digestive system    04970 Salivary secretion     110309267 (Adcy4)    04971 Gastric acid secretion     110309267 (Adcy4)    04972 Pancreatic secretion     110309267 (Adcy4)    04976 Bile secretion     110309267 (Adcy4)   09156 Nervous system    04724 Glutamatergic synapse     110309267 (Adcy4)    04727 GABAergic synapse     110309267 (Adcy4)    04725 Cholinergic synapse     110309267 (Adcy4)    04723 Retrograde endocannabinoid signaling     110309267 (Adcy4)   09157 Sensory system    04742 Taste transduction     110309267 (Adcy4)    04750 Inflammatory mediator regulation of TRP channels     110309267 (Adcy4)   09149 Aging    04211 Longevity regulating pathway     110309267 (Adcy4)    04213 Longevity regulating pathway - multiple species     110309267 (Adcy4)   09159 Environmental adaptation    04713 Circadian entrainment     110309267 (Adcy4)    04714 Thermogenesis     110309267 (Adcy4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     110309267 (Adcy4)    05207 Chemical carcinogenesis - receptor activation     110309267 (Adcy4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     110309267 (Adcy4)    05163 Human cytomegalovirus infection     110309267 (Adcy4)   09165 Substance dependence    05032 Morphine addiction     110309267 (Adcy4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     110309267 (Adcy4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     110309267 (Adcy4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     110309267 (Adcy4) Enzymes [BR:mcal01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      110309267 (Adcy4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  110309267 NCBI-ProteinID:  XP_021037475 Ensembl:  MGP_CAROLIEiJ_G0019319 UniProt:  A0A6P5R2D1 LinkDB All DBs Position 14:complement(47191579..47207041) Genome browser AA seq 1077 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLILLLVIVLCALVALPAVAWASGRELTSDPS FLTTVLCALGGFSLLLGLASREQQLQRWTRPLSGLIWVALLALGYGFLFTGGVVSAWDQV SFFLFIIFTVYAMLPLGMRDAAAAGVISSLSHLLVLGLYLGWQPESQRALLPQLAANAVL FLCGNLVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQHSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRVATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVERADTEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAKGLLSSLEGHTMRPSLLMTR YLESWGAAKPFAHLSHLDCPVSTSTPLPEKAFSPQWSLDRSRTPRGLDDELDTGDAKFFQ VIEQLNSQKQWKQSKDFNLLTLYFREKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQM LVTTRPPALIITYSITFLLFFLLLFVCFSEHLTKCVQKGPKMLHWLPALSVLVATRPGFR VALGTATILLVFTMAIASLLFLPVSSDCLFLASNVSSVTFNASWEMPGSLPLISIPLISI PYSMHCCVLGFLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLIARLYQSPS DSRPGVLKEPKLMGAIYFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLT RLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLEC LRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDTQQDAERSCSHLGT MVEFAVALGSKLGVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRME STGVLGKIQVTEETARALQSLGYTCYSRGSIKVKGKGELYTYFLNTDLTRTGSPSAS NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccccggcctcctcccagcgaagatctcttctacgaaacttac tacagcctgagccaacagtacccactgctgatactgcttttggtcattgtgctctgcgcg ctggtggcactgcccgccgtcgcctgggccagcggcagggagctgacctcagacccaagc ttcctgacaactgtgctgtgtgctttgggtggcttctctctgctattggggctcgcttcc cgggagcagcaactgcagcgatggacacgacctctttctggtctcatatgggttgcattg ctggctttgggctatggatttctgttcactgggggtgtggtgagtgcctgggaccaggtg tcttttttcctcttcatcatcttcaccgtgtacgccatgctgcccttgggcatgcgggat gctgctgctgcgggggtcatctcatccctctctcacctgctggtccttggactgtatctt gggtggcagcctgagtcacagagagctctgctaccacagttggcagcaaacgcggtgttg ttcctgtgtgggaacctggtgggggcgtaccacaaggccctgatggagcgagcattgcgg gccacgttccgggaggctcttagctctctgcactcacgccggaggctggacactgagaaa aagcaccaggagcacctcctcttgtccatccttcctgcctacctggcccgagagatgaaa gcagagatcatggcccggctgcaggctggacagcactcacggccagagaacacaaacaac tttcacagcctgtacgtcaagaggcaccaaggagtgagtgtgctgtatgctgacatcgtg ggcttcacgcggctggccagtgagtgttccccaaaggagctggtgctcatgctgaatgag ctctttggcaagttcgaccagattgccaaggagcacgaatgcatgcggatcaagatcctg ggagactgttactactgtgtgtccgggctgcccctctcgctgcctgaccacgctatcaat tgtgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggtagccaccggt gtggatatcaacatgcgcgtgggcgtgcactcgggcagcgttctctgtggagtcatcggg ctacagaagtggcagtatgatgtctggtcccatgatgtcacattggccaaccatatggaa gcagggggtgtaccaggacgagtgcacatcacaggggccacactggccctgctagcagga gcttatgctgtggaaagggcagacacggaacaccgagacccgtaccttcgggagctaggc gaacctacatacctggtcattgaccctcgggctgaggaggaagacgagaagggcaccgca aaaggattgctgtcttctctggaggggcacacgatgcgtccgtcacttctgatgactcgc tatctggagtcttggggtgcagccaagcctttcgcccacctaagccaccttgactgtcct gtgtctacctccactccactaccggagaaagccttcagcccccagtggagcctggaccgg agtcgcaccccccggggactagatgatgagctggacactggtgatgccaagttcttccag gtcatcgaacaactcaactctcagaaacagtggaagcagtcgaaggacttcaacctcctg acgctgtacttcagagagaaggagatggagaaacagtatcggctctctgcacttccagcg ttcaaatactacgcagcctgcaccttcctggtttttctgtccaacttcactatccaaatg ctggtgacaaccaggcccccagctctgatcatcacctacagcatcaccttccttctcttc tttctcctcctcttcgtctgcttctcagagcacctgacgaagtgtgtccagaaaggtccc aagatgttgcactggctgcctgcactgtctgtcctggtggccacacggccaggatttcga gtagccctgggcacggccaccatcctcctagtattcactatggccatcgccagcctgctc ttcttaccagtgtcatcagactgccttttcctggcttccaatgtgtcgtctgtgactttc aatgcttcctgggagatgccaggatccctgcccctcatcagcatccccctcatcagcatc ccatactccatgcattgctgcgtgttgggtttcctctcctgctccctttttctgcacatg agcttcgaactgaagctgctcctacttctgctgtggctggtggcatcttgttccctattt ctgcattcccacgcctggctgtccgactgcctcattgcccgcctttatcaaagcccttca gactccaggccaggggtgctgaaggaacccaagctgatgggagctatctacttcttcatc ttcttcttcacactcctggtcctggctcggcagaatgagtattactgccgcctggacttc ctgtggaaaaagaaactgaggcaggagcgagaggagactgagacgatggagaacctgacc cggctcctcctggagaatgtactccctgcacacgtggccccccagttcatcggccagaac cggcgcaatgaggacctctaccaccagtcgtacgaatgcgtgtgtgtcctcttcgcatcg gtcccagactttaaggaattctactctgaatccaacatcaaccacgaggggctggagtgc ctgcggctgctcaatgagatcatcgctgactttgatgagctgctctccaagccaaagttc agtggagtagaaaagatcaaaactattggcagtacctacatggcagccacaggcttaaat gccacctctggacaggatactcaacaggatgctgagagaagctgcagtcatctgggcacc atggtggaatttgcagtggccctggggtctaagctgggtgtcatcaacaagcactcgttc aacaacttccgcctgcgtgtggggttgaaccacggaccagtagtagcaggggtgattggg gcgcagaagccacagtatgacatctgggggaacacagtgaatgtggccagccgcatggag agcacaggcgttctcggcaagatccaagtgactgaggagacagcgcgggccctgcagtct ctgggttacacatgctatagcagaggcagcatcaaggtcaaaggcaaaggggaactctat acctacttcctgaacacagacctgacgcggaccggatctccctcagcatcctag

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