Mus caroli (Ryukyu mouse): 110310987
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Entry
110310987 CDS
T05910
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal00790
Folate biosynthesis
mcal01100
Metabolic pathways
mcal01240
Biosynthesis of cofactors
mcal01523
Antifolate resistance
mcal04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
110310987 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
110310987 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
110310987 (Fpgs)
Enzymes [BR:
mcal01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
110310987 (Fpgs)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
110310987
NCBI-ProteinID:
XP_021039835
Ensembl:
MGP_CAROLIEiJ_G0023444
UniProt:
A0A6P5R500
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Position
2:complement(28552786..28577587)
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AA seq
587 aa
AA seq
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MSWARSRLCTTLSLAAVSARGATTEGAARRGLSAWPAPQEPGMEYQDAVRTLNTLQTNAS
YLEQVKRQRSDPQAQLEAMEMYLARSGLQVEDLNRLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFSSPHMVQVRERIRINGKPISPELFTKHFWCLYNQLEEFKDDSHVSMPSYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAFDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKPGVPAFTVVQPEGPLAVLRDRAQQIACPLYLCPPLEALEEVGLPLSLGLEGA
HQRSNAALALQLAHCWLERQDHQDIPELKVSRPSIRWQLPLAPVFRPTPHMRRGLRDTVW
PGRTQILQRGPLTWYLDGAHTTSSVQACVHWYRQSLERSKRTDGGSEVHILLFNSTGDRD
SAALLKLLQPCQFDYAVFCPNVTEVSSIGNADQQNFTVTLDQVLLRCLQHQQHWNCLAEK
QASSNLWSSCSPDPAGPGSLLLAPHPPQPTRTSSLVFSCISHALLWISQGRDPIFQPQSL
PRNLLNHPTANSGASILREAAAIHVLVTGSLHLVGGVLKLLDPAMSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgggcgcggagccgcctgtgcacgactctgtccctggcagctgtttctgcgcgt
ggtgcaacgacggagggcgcggcgcggcggggtttgagcgcgtggccagcgccacaggag
ccgggcatggagtatcaggatgctgtacgcacgctcaacaccctgcaaaccaatgccagc
tacctggagcaggtaaagcgccaacggagtgacccccaggcgcagctggaggctatggag
atgtacctggcacggagtggactgcaggtggaggacttgaaccggctaaacattattcat
gtcactgggaccaaagggaagggctccacctgtgccttcaccgaacggatcctgcggaat
tacggcctgaagactggcttctttagctctcctcacatggtgcaggtgcgggagcggatt
cgaatcaacgggaaacccatcagccccgagctcttcaccaagcacttctggtgcctctat
aatcagctggaggagttcaaggacgacagccacgtctccatgccctcttacttccgcttc
ctcacgctcatggccttccatgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttttgactgcaccaacatcatcagaaagccagtggtgtgtggc
gtctcctctcttggcattgaccacaccagtctactaggagatacggtggagaaaatagca
tggcagaaagggggcatctttaagcctggtgtccctgccttcactgtggtgcagccagaa
ggtcccctggcagtgctgagagatcgagcccagcagattgcatgcccactgtacctgtgt
ccgccattggaagccctggaggaggttggactgccattgagcctgggtctggagggagca
caccagcggtctaatgcagccttggccttgcagctggcccactgttggctggagcggcag
gaccaccaagacatcccggagctgaaggtatccaggccaagcatacggtggcagctgccc
ctggcacctgtgttccgccctacccctcacatgaggcgtgggcttcgggacacagtgtgg
cctggccggacacagatactccagcggggaccccttacctggtaccttgatggcgcccat
accaccagcagtgtgcaggcctgtgtgcactggtaccgccagtcattggagcgcagcaaa
cgcaccgatggagggtctgaagtacacatcttgctcttcaactctactggtgacagggac
tctgctgccctgctgaagctgctgcagccctgccagtttgactacgctgtcttctgcccc
aacgtgacagaggtttcatccataggaaacgcagaccagcagaacttcactgtgactctg
gaccaggtgctgcttcgctgcctccaacaccagcagcattggaactgcctggccgagaaa
caggccagctccaacctctggagcagctgcagcccagaccctgctgggccaggctccctg
ctgctggccccgcacccacctcagcctactaggacgagctccctcgttttcagctgcatc
tcccacgccttgctgtggatcagccaaggccgggatcccatctttcagccccagagcctt
ccaaggaatcttctcaaccaccccacagccaacagcggggccagcattctccgtgaggcc
gctgccatccatgtactggttacaggaagcctgcacctggtgggtggggttctgaagctg
ctggatccggcgatgtcccagtag
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