| Entry |
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| Symbol |
Abcc1
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| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
mcal Mus caroli (Ryukyu mouse)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:mcal00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
110311227 (Abcc1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
110311227 (Abcc1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
110311227 (Abcc1)
04981 Folate transport and metabolism
110311227 (Abcc1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
110311227 (Abcc1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
110311227 (Abcc1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:mcal02000]
110311227 (Abcc1)
Enzymes [BR:mcal01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
110311227 (Abcc1)
Transporters [BR:mcal02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
110311227 (Abcc1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
16:10889479..10990589
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| AA seq |
1528 aa
MALRSFCSADGSDPLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLWSCFPLYFFYLSRH
DRGYIQMTHLNKTKTALGFFLWIICWADLFYSFWERSQGVLRAPVLLVSPTLLGITMLLA
TFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAQVDVFRDSTFYLYFT
LVLVQLVLSCFSDCSPLFSETVHDRNPCPESSASFLSRITFWWITGMMVHGYRQPLESSD
LWSLNKEDTSEEVVPVLVNNWKKECDKSRKQPVRIVYAPPKDPTKPKGSSQLDVNEEVEA
LIVKSPHKDREPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPKILELIINFVNDREAP
DWQGYLYTALLFVSACLQTLALHQYFHICFVSGMRIKTAVVGAVYRKALLITNAARKSST
VGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYFLWLSLGPSVLAGVAVMILMVPL
NAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQEELKVL
KKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNIL
PMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEGNSITVKNATFTWARGEPPT
LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQND
SLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLAR
AVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIV
MSGGKISEMGSYQELLDRDGAFAEFLRTYANAEQDLASEDDSVSGSGKESKPVENGMLVT
DTVGKHLQRHLSNSSCHSGDTSQQHSSTAELQKAGAKEETWKLMEADKAQTGQVQLSVYW
NYMKAIGLFITFLSVFLFLCNHVSALASNYWLSLWTDDPPVVNGTQANRNFRLSVYGALG
ILQGVSIFGYSMAVSIGGIFASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTV
DSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRL
ESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRL
ECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVER
LKEYSETEKEAPWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKV
GIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGS
LRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARA
LLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKG
EVRECGAPSELLQQRGIFYSMAKDAGLV |
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| NT seq |
4587 nt +upstreamnt +downstreamnt
atggcgctgcgtagcttctgcagcgctgatggctccgatccactctgggactggaatgtc
acatggcataccagcaaccccgactttaccaagtgctttcagaacacggtcctcacatgg
gtgccttgtttctacctctggtcctgtttccccctctacttcttctatctctctcgccat
gaccggggctacatccagatgacacacctcaacaaaaccaaaactgccttaggattcttt
ctgtggatcatctgctgggcagacctcttctactctttctgggaaagaagtcagggagtg
ctccgagccccagtgttactggtcagcccaacactgctgggcatcaccatgctgctcgcc
acctttttaattcagcttgaacgaaggaagggagtccagtcctcgggaattatgcttact
ttctggcttgtagccctactctgtgcccttgccatcttgagatctaagatcatctctgcc
ttaaaaaaggatgctcaagtggacgtgtttcgagattccacgttctatctgtacttcacc
cttgtgcttgttcagctcgtgctgtcctgcttctcagactgctcacccctgttctctgaa
actgtccatgaccggaatccatgcccagaatccagtgcctctttcctttccaggatcact
ttctggtggattacagggatgatggtgcacggctaccgccagcccctggagagcagtgac
ctctggtcattgaataaggaggacacttcagaagaagtggtacctgtgctggtgaataac
tggaagaaggaatgtgataagtcaaggaagcagcctgtacggattgtgtatgcccctccc
aaagatcccaccaagcctaagggaagttcccagttggatgtgaatgaggaggtcgaggca
ctcattgtcaagtcgccccacaaggatcgggagccctctctattcaaggtgttatacaag
acttttggcccctacttcctcatgagcttcctgtacaaggccctccatgacctgatgatg
tttgccggtcccaagatcttagaattgattatcaacttcgtgaatgacagggaggctccc
gactggcagggctacttgtacacagcactgctgtttgtcagcgcttgtctgcagacactg
gcactccaccagtactttcatatctgcttcgtcagtggcatgcgcatcaagactgctgtg
gtgggcgctgtctatcgtaaggctcttttgatcaccaatgcagctagaaaatcttccacg
gtcggagagattgtcaacctcatgtccgtggatgctcagcgcttcatggacttggccacg
tacattaacatgatctggtcagcccctctgcaagtcatcctagccctctacttcctgtgg
ctgagcctgggcccttctgtgctggctggagtggctgtgatgattctcatggtaccctta
aatgctgtgatggccatgaagaccaagacctaccaggtggcacacatgaagagcaaagac
aaccgaatcaagctgatgaacgagatcctcaatgggatcaaagtcctcaagctgtacgcc
tgggagctggccttccaggacaaagtcatgagcatcaggcaggaggagctcaaggtgctg
aagaaatctgcctacctggcagctgtaggcacattcacgtgggtgtgcacacctttcctg
gtggccctgtcaacctttgctgtctttgtgactgtggatgagagaaatatcctagatgca
aagaaagcctttgtgtccctagccctgttcaatatcttgcgcttcccactcaacatcctg
cccatggttatcagcagcattgtgcaggccagcgtgtccctcaagcgtctcaggattttt
ctgtctcatgaggagctggagccagacagcattgagcggaggtcgatcaagagtggcgaa
ggaaatagcatcactgtgaagaatgcaaccttcacgtgggccaggggtgaacctcccaca
ctgaatggcatcaccttctccattcctgaaggagcccttgtggccgtggtgggccaggta
ggctgcgggaagtcatctctgctgtcagccctgctggctgagatggacaaggtggaggga
catgtgactctcaagggctccgtggcctacgtgccccagcaggcctggattcagaatgac
tccctccgagagaacatactgtttgggcaccccctgcaggaaaattactacaaggcagtt
atggaagcctgtgcccttcttccggatttggaaatcctgcccagtggggaccgcacagag
attggtgagaagggtgtgaacctgtcagggggccagaagcagcgtgtgagcctggcccgg
gctgtgtactctaactctgacatctacctctttgatgaccccctctcggctgtggatgca
catgttgggaagcacatctttgagaaggtggttggtcccatgggcctactgaagaacaag
acacggatcctggtcacccatggtatcagctacctgccccaagtggatgtcatcattgtc
atgagtggcggcaagatctcagagatgggttcttatcaggagctgctagaccgggatggg
gccttcgctgagttcctgcgcacctatgccaacgctgagcaggacctggcctcggaggat
gacagtgtcagtggttcagggaaggagtcaaagccggtggaaaatgggatgctggtgaca
gacactgtaggaaagcacctgcagaggcatctcagcaactcgtcttgccacagtggagat
actagccagcagcacagcagcacagccgaactgcagaaggctggagctaaggaggagacg
tggaagctaatggaagcagacaaggcccagacagggcaggtgcagctgtcagtgtattgg
aactacatgaaggccattggcctcttcatcaccttcttgagtgtcttccttttcctgtgc
aaccatgtatctgcactggcctctaactattggctgagcctctggacagatgacccccct
gttgtcaatgggactcaggcgaacaggaattttcggctgagtgtctatggggccttgggc
atcttgcaaggtgtatcaatatttggctactccatggctgtgtccattgggggcatcttt
gcctcccgtcgcctgcacctggacctgctatacaatgttctgcgatcacccatgagtttc
ttcgagcgtacacccagtgggaacctagtgaaccgattctccaaggagctggatacagtg
gactccatgatcccgcaggtcatcaagatgttcatgggttcactcttcagtgtcattgga
gctgtcatcatcatcctactggccacgcccattgccgcagtcatcatcccgcccttgggt
ctggtttacttctttgtgcagaggttctatgtggcttcctctagacaactgaagcgcctc
gagtctgtcagccgttcccctgtgtactcacacttcaatgagaccttgctgggagtcagt
gtcatccgtgcttttgaggagcaggagcgcttcattcaccagagtgacctgaaagtagat
gagaaccagaaggcctactaccccagcattgtggccaacaggtggcttgctgtgcgcctt
gagtgtgtgggcaactgcattgtgctgtttgctgccctctttgcagtcatctcccggcac
agcctcagtgctggcttggtgggcctttctgtgtcttactcactgcagataactgcatac
ttgaactggctggttcgaatgtcctctgagatggagaccaacattgtggcagtggagaga
ctgaaggagtattctgaaaccgagaaggaggctccttggcaaatccaggaaacagctccc
cccagcacctggccccattcaggccgtgtagagttccgggattactgcctgaggtatcga
gaagacttggacttggttctcaagcacataaatgtcaccattgagggtggagaaaaggtg
ggtattgtaggtcgcacgggagctgggaaatcatctctcaccctgggtttgttccggatc
aatgagtctgcagaaggggagatcatcattgatggggtcaacatcgccaagattggcctg
cacaacctgcgcttcaagatcaccatcattccacaggatcctgttttgttctcgggttcc
ctccgcatgaacttggaccctttcagtcagtattctgatgaagaagtctggatggccctg
gaacttgctcatctaaagggctttgtgtcagccttgcctgacaagctgaaccatgagtgt
gcagaaggtggagagaacctgagtgtggggcagcgacagcttgtgtgcctggcccgggct
ctgctgcggaagacaaagattctagtgttggacgaggctaccgcagctgtggacctagag
acagacaaccttatccagtccaccatccggacgcagtttgaagactgtactgtgctcacg
attgctcatcggcttaacaccataatggactacacacgggtgattgtcctggacaaagga
gaagttcgggagtgtggtgcaccctctgagctcctgcagcaaagaggcatcttctacagc
atggccaaggatgctggcttggtgtga |
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