Mus caroli (Ryukyu mouse): 110311510
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Entry
110311510 CDS
T05910
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal00230
Purine metabolism
mcal00670
One carbon pool by folate
mcal01100
Metabolic pathways
mcal01523
Antifolate resistance
Module
mcal_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110311510 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
110311510 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
110311510 (Gart)
Enzymes [BR:
mcal01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
110311510 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
110311510 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
110311510 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_4
ATP-grasp_2
Dala_Dala_lig_C
RimK
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
110311510
NCBI-ProteinID:
XP_021040510
Ensembl:
MGP_CAROLIEiJ_G0020964
UniProt:
A0A6P5R6W9
LinkDB
All DBs
Position
16:complement(86011157..86037580)
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSPHVKQVLVAPGNAGTACAGKISNTAVSVNDHSALAQ
FCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAAQLESSKKFAKEFMDRHEIP
TAQWKAFTNPEDACSFITSANFPALVVKASGLAAGKGVIVAKSQAEACRAVQEIMQEKSF
GAAGETVVVEEFLEGEEVSCLCFTDGKTVAEMPPAQDHKRLLDGDEGPNTGGMGAYCPAP
QVSKDLLVKIKNTILQRAVDGMQQEGMPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVMQSTLDGQLSTSLPVWLENHSAVTVVMASKGYPGAYTKGMEITGFPEA
QALGLQVFHAGTALKDGKVVTSGGRVLTVTAVQENLMSALAEARKGLAALKFEGAIYRKD
IGFRAVAFLQRPRGLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCSKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSTTEAVIAGIAAACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERHQKLP
QLERITEGDAVVGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGGCGDQTLGDLLLTPTR
IYSHSLLPIIRSGRVKAFAHITGGGLLENIPRVLPQKFGVDLDASTWRVPKVFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKDQAEQVLHDIRRQQEEAWVIGSVVACPEDSPRVRVKN
LIETIQTNGSLVANGFLRSNFPVQQKKARVAVLISGTGSNLQALIDSTRDPKSSSHIVLV
ISNKAAVAGLDRAERAGIPTRVINHKLYKNRVEFDTAVDHVLEEFSVDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVRRGDTVATLSERVRVAEHKIFPAALQLVASGAVQLREDGKIHWAKEQ
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtccttgtcattggtagtggtggaagggaacataccctagcctggaaa
ctcgcacagtctcctcatgtcaaacaagtgttggttgccccaggaaatgcaggcaccgcg
tgcgctgggaagatctccaatactgctgtctctgtcaatgatcacagtgccctcgctcag
ttctgcaaagatgaaaagattgaactcgtagttgtcggaccagaggcccctctggctgca
ggaattgttggggacctgacctctgcaggagtacgatgcttcggccccacagcacaagca
gctcaattagagtccagtaagaagtttgccaaagagtttatggaccgccatgaaatccca
actgcacagtggaaagcattcaccaaccctgaagatgcctgcagctttattaccagcgcg
aactttcctgctttggttgtgaaggccagtggccttgcagcagggaagggggtgattgtg
gccaagagccaagcggaggcctgcagagctgtacaggagatcatgcaagaaaagtctttc
ggagcagctggtgagaccgtggttgtggaagagtttctggaaggggaagaagtgtcttgc
ctgtgcttcactgatgggaagacggtggccgaaatgcccccagcacaagaccataagcga
ctgctggatggagatgagggccccaacaccggggggatgggagcctactgcccagcacct
caggtttctaaggacttgttagtaaaaattaagaacactattcttcagagagcagtagac
ggcatgcagcaggagggtatgccgtacacaggaattctttatgctggtataatgctgacc
aaagatggcccaaaagtgttggagtttaattgccgttttggtgatccggaatgccaggtc
atcctcccacttcttaaaagtgacctctatgaagtgatgcagtccaccttggatggccag
ctgagcacatctctgcctgtttggctagaaaaccacagcgccgtaactgtcgtcatggcg
agtaaggggtaccctggagcctacaccaaaggcatggagattacagggtttcctgaggcc
caggctttaggactgcaggtattccatgcaggcactgctcttaaagatggcaaagtggtg
accagcggaggcagggtcctcaccgtgacagctgtccaggaaaatctcatgtcagccctt
gctgaggccaggaaaggactcgctgctctaaagtttgagggagccatttatagaaaggac
attggcttccgtgctgtggccttcctccagcggcccaggggcttgacttacaaggactcc
ggagtagacattgcagctggaaatatgctggttaagaaaattcagcctttagcaaaagcc
acctccagaccaggctgcagcgttgacctcgggggctttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctctggaacagatggtgtcggaactaaacta
aagattgcccagctgtgcagtaagcacgattccatcgggcaggatctggtggccatgtgt
gtgaacgacatcctcgcccagggagcagagcccctcttcttccttgactacttttcctgt
gggaagcttgacctcagtacaactgaagccgtcattgctggaattgctgcagcttgccgg
caggctggctgtgccttgctgggtggggagacagcagagatgcccgacatgtaccctcct
ggagagtatgatcttgctgggtttgctgttggtgctatggagagacaccagaagctccct
cagctagaaaggatcaccgaaggggatgctgttgttggagtggcttcatctggtcttcac
agcaatgggtttagccttgtgaggaaaatcgtggagaggtcttccctccagtactcctcc
ccagctcctggtggttgtggagatcagaccttaggggacttacttctaactccaaccagg
atctacagccattcactgctgcccatcatccgttcaggacgtgtcaaagcttttgctcat
atcactggaggcggattgctggaaaacatccccagagtcctccctcagaagtttggagta
gatttagatgccagcacctggagggtccccaaggtcttctcatggctacagcaggaagga
cagctctctgaagaagaaatggccaggacattcaactgtggggttggagctgccctggtg
gtgtcaaaggaccaggcagagcaggttctgcatgacattcggcggcagcaggaggaagcc
tgggtgataggcagtgtcgttgcatgtcctgaagattcccctcgtgtcagagttaagaat
ctgattgaaaccatacaaacaaatgggtcattggtggcaaatggcttcctgagaagtaat
ttccctgtccagcaaaagaaggcaagagtggctgtcttgatatctggaacagggtcaaac
ctccaggcgctcatagacagcacccgggatcctaagagctcctcacatattgttctcgtc
atctccaacaaagccgccgtagccggcttagaccgagcagagcgagccggtattcccacc
agggtaattaatcacaaattatataaaaatcgtgttgagtttgacactgcagttgaccac
gtcctggaagagttctcggtagacatcgtctgtctcgcagggttcatgaggatcctctct
gggcccttcgtcagaaaatgggacgggaaaatgctcaacatccacccatccttgctccct
tcttttaagggttcaaatgcccacgagcaagtcctggaagctggagtcacaattactggg
tgtaccgtacactttgtcgctgaagatgtagatgccggacaaatcatcctgcaggaagct
gtccctgtgcggaggggtgacactgtggcaacgctgtctgaacgggtcagagtggcagaa
cataagatctttcctgccgccctccagctggtggccagtggggctgtgcagctgcgagaa
gatggcaagatccactgggccaaggagcagtga
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