Mus caroli (Ryukyu mouse): 110312423 Help Entry 110312423         CDS       T05910                                  Symbol Sos1 Name (RefSeq) son of sevenless homolog 1   KO K03099   son of sevenless Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal01521   EGFR tyrosine kinase inhibitor resistance mcal01522   Endocrine resistance mcal04010   MAPK signaling pathway mcal04012   ErbB signaling pathway mcal04014   Ras signaling pathway mcal04062   Chemokine signaling pathway mcal04068   FoxO signaling pathway mcal04072   Phospholipase D signaling pathway mcal04150   mTOR signaling pathway mcal04151   PI3K-Akt signaling pathway mcal04510   Focal adhesion mcal04540   Gap junction mcal04630   JAK-STAT signaling pathway mcal04650   Natural killer cell mediated cytotoxicity mcal04660   T cell receptor signaling pathway mcal04662   B cell receptor signaling pathway mcal04664   Fc epsilon RI signaling pathway mcal04714   Thermogenesis mcal04722   Neurotrophin signaling pathway mcal04810   Regulation of actin cytoskeleton mcal04910   Insulin signaling pathway mcal04912   GnRH signaling pathway mcal04915   Estrogen signaling pathway mcal04917   Prolactin signaling pathway mcal04926   Relaxin signaling pathway mcal04935   Growth hormone synthesis, secretion and action mcal05034   Alcoholism mcal05160   Hepatitis C mcal05161   Hepatitis B mcal05163   Human cytomegalovirus infection mcal05165   Human papillomavirus infection mcal05200   Pathways in cancer mcal05205   Proteoglycans in cancer mcal05206   MicroRNAs in cancer mcal05207   Chemical carcinogenesis - receptor activation mcal05208   Chemical carcinogenesis - reactive oxygen species mcal05210   Colorectal cancer mcal05211   Renal cell carcinoma mcal05213   Endometrial cancer mcal05214   Glioma mcal05215   Prostate cancer mcal05220   Chronic myeloid leukemia mcal05221   Acute myeloid leukemia mcal05223   Non-small cell lung cancer mcal05224   Breast cancer mcal05225   Hepatocellular carcinoma mcal05226   Gastric cancer mcal05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mcal00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     110312423 (Sos1)    04012 ErbB signaling pathway     110312423 (Sos1)    04014 Ras signaling pathway     110312423 (Sos1)    04630 JAK-STAT signaling pathway     110312423 (Sos1)    04068 FoxO signaling pathway     110312423 (Sos1)    04072 Phospholipase D signaling pathway     110312423 (Sos1)    04151 PI3K-Akt signaling pathway     110312423 (Sos1)    04150 mTOR signaling pathway     110312423 (Sos1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     110312423 (Sos1)    04540 Gap junction     110312423 (Sos1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     110312423 (Sos1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     110312423 (Sos1)    04660 T cell receptor signaling pathway     110312423 (Sos1)    04662 B cell receptor signaling pathway     110312423 (Sos1)    04664 Fc epsilon RI signaling pathway     110312423 (Sos1)    04062 Chemokine signaling pathway     110312423 (Sos1)   09152 Endocrine system    04910 Insulin signaling pathway     110312423 (Sos1)    04912 GnRH signaling pathway     110312423 (Sos1)    04915 Estrogen signaling pathway     110312423 (Sos1)    04917 Prolactin signaling pathway     110312423 (Sos1)    04926 Relaxin signaling pathway     110312423 (Sos1)    04935 Growth hormone synthesis, secretion and action     110312423 (Sos1)   09156 Nervous system    04722 Neurotrophin signaling pathway     110312423 (Sos1)   09159 Environmental adaptation    04714 Thermogenesis     110312423 (Sos1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     110312423 (Sos1)    05206 MicroRNAs in cancer     110312423 (Sos1)    05205 Proteoglycans in cancer     110312423 (Sos1)    05207 Chemical carcinogenesis - receptor activation     110312423 (Sos1)    05208 Chemical carcinogenesis - reactive oxygen species     110312423 (Sos1)    05231 Choline metabolism in cancer     110312423 (Sos1)   09162 Cancer: specific types    05210 Colorectal cancer     110312423 (Sos1)    05225 Hepatocellular carcinoma     110312423 (Sos1)    05226 Gastric cancer     110312423 (Sos1)    05214 Glioma     110312423 (Sos1)    05221 Acute myeloid leukemia     110312423 (Sos1)    05220 Chronic myeloid leukemia     110312423 (Sos1)    05211 Renal cell carcinoma     110312423 (Sos1)    05215 Prostate cancer     110312423 (Sos1)    05213 Endometrial cancer     110312423 (Sos1)    05224 Breast cancer     110312423 (Sos1)    05223 Non-small cell lung cancer     110312423 (Sos1)   09172 Infectious disease: viral    05161 Hepatitis B     110312423 (Sos1)    05160 Hepatitis C     110312423 (Sos1)    05163 Human cytomegalovirus infection     110312423 (Sos1)    05165 Human papillomavirus infection     110312423 (Sos1)   09165 Substance dependence    05034 Alcoholism     110312423 (Sos1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     110312423 (Sos1)    01522 Endocrine resistance     110312423 (Sos1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH PH_19 PH_10 IQ_SEC7_PH RHG20_PH DUF6018 Takusan Motif Other DBs NCBI-GeneID:  110312423 NCBI-ProteinID:  XP_021041656 Ensembl:  MGP_CAROLIEiJ_G0021908 UniProt:  A0A6P5RC24 LinkDB All DBs Position 17:complement(76114199..76199715) Genome browser AA seq 1319 aa AA seqDB search MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLREVLGY KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITRQDIKVAMCADKVLMDMFHQDV EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSN DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR DILRPGFHGHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL EEKSEDQEDKECMKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL PGASSAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAA LISLQYRSTLERMLDVTVLQEEKEEQMRLPSAEVYRFAEPDSEENILFEENVQPKAGIPI IKAGTVLKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADR IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLRRHGKELINFSK RRRVAEITGEIQQYQNQPYCLRVEPDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRH PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP NSPRTPLTPPPASGTSSNTDVCSVFDSDHSASPFHSRSASVSSISLSKGTDEVPVPPPVP PRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSLSDPPESPPLL PPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLP SPPLTQEMDLHSIAGPPVPPRQSTSQLIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS NT seq 3960 nt NT seq  +upstreamnt  +downstreamnt atgcaggcgcagcagctgccttacgagtttttcagcgaggagaacgcgcccaagtggcgg gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcaccctactcttgagtct aatgatgatgctcttcagtatgttgaagaattaattttgcaattactaaatatgctatgc caagctcagccccggagtgcttcagatgtggaggaacgtgttcaaaaaagttttcctcat ccaattgataagtgggcaatagctgatgcccagtcagccattgaaaagaggaagagaaga aatcctttatccctgccagcagaaagaattcatcatttattaagggaggtcctcggttat aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagat attttaaagctggtggggaattatgtaagaaatatacggcattatgaaattacaagacaa gacattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta gaagatataaatatcttatctttaactgatgaagagccttccacctcaggagaacaaact tattatgatttggtaaaagcattcatggcagaaattcgacagtatataagagaattaaat ctaattataaaagtatttcgagaaccctttgtctctaattccaaattgttttcatctaat gatgtagaaaacatatttagtcgtatagtagatatacatgaacttagtgtaaagttactg ggccatatagaagatactgtagaaatgacagatgaaggcagtccccacccattagtagga agctgttttgaagacttagcagaagaactggcatttgacccatatgagtcatatgctcgg gatattttacgacctggattccatggccattttcttagtcagttatcaaagcctggggca gcactttatttgcagtccataggcgaaggcttcaaagaagctgtccagtacgtcctgccc cggctgctgcttgcccctgtgtaccactgtttgcattactttgaacttctgaagcagtta gaagaaaagagtgaagatcaagaagacaaggagtgtatgaagcaagcaataacagccctg cttaatgtccaaagtggcatggaaaaaatttgctccaaaagtcttgcaaaacgaagacta agtgagtctgcatgtcggttttacagccagcagatgaaggggaaacaactggccatcaag aagatgaacgagattcagaagaacatcgatggctgggaggggaaggacattggacagtgc tgcaatgagttcataatggaaggaactcttacacgtgtaggagccaaacacgagagacac atatttctcttcgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactc cctggtgctagcagtgcagaatatcggcttaaagaaaagttttttatgcgaaaggtacag attaatgataaagatgacaccagtgaatacaagcatgcttttgaaatcattctgaaagac ggcaatagtgttatattttctgccaagtcagctgaagagaaaaacaactggatggcagcc ctgatctctttgcagtaccgcagcaccctggagaggatgctggacgtaacggtgctgcag gaggagaaggaggagcagatgaggctgcccagtgctgaagtgtacaggtttgcagaacct gactccgaggagaatattctattcgaagagaatgtgcagcccaaagctgggatccccatt atcaaagcagggactgtgctcaagctcattgagaggcttacataccatatgtacgcagat ccaaattttgttcggacgtttcttacaacatacagatccttttgcaaacctcaagaacta ctgagtcttctaatagaaagatttgaaattccagagcctgagccaacagaagctgatcgc atagctatagagaatggagatcagcccctgagtgcagagctgaagaggtttagaaaggaa tatatccagcctgtgcagttgagggtgttaaatgtgtgtcggcactgggtggagcaccat ttctatgactttgaaagagatgcagaccttttacagagaatggaggaatttattggaaca gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaagataatccaaaggaaa aaaattgcaagagacaatggcccaggtcataacattacatttcagagctcacctcccaca gttgagtggcacataagcagacctgggcacatagagacttttgacttgctcaccttacac ccaatagaaattgctcggcaactcactttacttgaatcagatctataccgagctgtgcag ccatcagaattagttggaagtgtgtggacaaaagaagataaagaaattaattctcccaac cttctgaagatgattcggcacaccactaacctcaccctgtggtttgagaaatgtattgta gaaacagaaaacttagaagaaagagtagctgtagtgagtcgaataattgagattctacaa gtctttcaagagctgaacaacttcaatggtgtcctggaagttgtcagtgctatgaactcg tctcctgtttacagactagaccacacatttgagcaaataccaagtagacaaaagaaaatt ttagaagaagctcatgagttgagtgaagatcactataagaaatatttggcaaaactcagg tctattaatccaccgtgtgtgcctttctttggaatttatctcacaaatatcctgaagaca gaagagggcaaccctgaggtcctgaggagacatgggaaagagcttattaacttcagcaag aggaggagagtggccgagatcacaggcgagatccagcagtaccagaaccagccctactgc ttacgggtggagccggacatcaagaggttctttgaaaacttgaatccaatgggaaatagc atggagaaagaatttacagactatctattcaacaaatccttagaaatagaaccccggcac cctaagcctcttccgagattcccaaaaaaatacagctatcccctaaaatctcctggtgtt cgtccatcaaatccaagaccaggaaccatgagacatcccacacctctgcagcaggagcca agaaaaattagctacagtcggattcctgaaagtgaaacggaaagcacagcatctgcacca aactctccgcggaccccactgacgccgcctcccgcatctggcacgtccagcaacacagat gtttgcagcgtgttcgattctgaccattcagcaagcccttttcattcaagatctgcttca gtctcatctataagtttatccaagggcactgatgaagtgcctgttccccctcctgtaccc cctcgaagacgtccagagtctgccccagctgaatcctccccatccaagattatgtctaag cacttggacagccccccagctattcctcctaggcaacccacatccaaagcctattcacca cgctattcaatatcagatcggacctctctatcagatcctcctgaaagccctcccttgtta ccaccacgggaacctgtgaggacacctgatgttttctcaagctcgccattacatctccaa cctcctcctttgggcaaaaagagtgatcatggcaatgccttcttcccaaacagcccatcc ccttttacaccgccacccccccaaaccccttctcctcatggcacgagaaggcatctgcca tcaccaccactgacacaggaaatggacctccattccattgctgggcctcctgttcctcca cgacaaagcacttctcaacttatccccaaactccctccaaaaacttataaaagggagcac acacacccatccatgcatagagatggaccaccactgctggagaatgcccattcttcctga

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