Mus caroli (Ryukyu mouse): 110312509
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Entry
110312509 CDS
T05910
Symbol
Pde10a
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X5
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal00230
Purine metabolism
mcal01100
Metabolic pathways
mcal04024
cAMP signaling pathway
mcal05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110312509 (Pde10a)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
110312509 (Pde10a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
110312509 (Pde10a)
Enzymes [BR:
mcal01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
110312509 (Pde10a)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
110312509 (Pde10a)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
110312509
NCBI-ProteinID:
XP_021041820
Ensembl:
MGP_CAROLIEiJ_G0021060
UniProt:
A0A6P5R3D5
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Position
17:complement(7899203..8346177)
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AA seq
795 aa
AA seq
DB search
MEDGPSNNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRK
TNKEDEPSPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKADG
FALYFLGECNNSLCVFTPPGMKEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDE
RFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWAS
VAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQ
VDHKNKELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPR
FNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALA
LHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHFDIGP
FENMWPGIFVYMIHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAIL
QNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVS
ILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQSH
RDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDE
VPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETAMWISGPGPA
PSKSTSEKLNVKVDD
NT seq
2388 nt
NT seq
+upstream
nt +downstream
nt
atggaagatggaccctctaacaatgcgagttgcttccgaaggctgaccgagtgtttcctc
agccccagtttgacggatgaaaaggtgaaggcctatctttctctccatccccaggtatta
gatgaatttgtttctgaaagtgttagtgcagagactgtggaaaagtggctgaagaggaaa
accaacaaagaagatgaaccgtctcccaaggaagtcagcaggtaccaggatacgaatatg
cagggagtcgtgtacgagctgaacagctacatagagcagcgcctggacacgggcggggac
aaccacctgctcctctatgagctcagcagcatcatcaggatagccacaaaagccgacgga
tttgcactgtacttccttggagagtgcaataatagcctgtgtgtgttcacaccacccggg
atgaaggaaggccaaccccggctcatccctgcagggcccatcacccagggtaccaccatc
tctgcctacgtggccaagtctaggaagacgctgctggtagaggacatccttggggatgag
cgatttccacgaggtactggcctggaatcaggaacccgaatccagtctgttctttgcttg
cccatcgtcactgccattggagacttgattggcatccttgaactgtacaggcactggggc
aaagaggccttctgcctcagccatcaggaggttgcaacagccaatcttgcttgggcttcc
gtagcaatacaccaggtgcaggtgtgtagaggtctcgccaaacagaccgaactgaatgac
ttcctactcgacgtatcaaagacatactttgataacatagtcgccatagactctctactt
gaacacatcatgatatatgcaaaaaatctagtgaacgccgaccgctgcgcgctcttccag
gtggaccacaagaacaaggagctgtactccgacctgtttgacattggggaggagaaggag
gggaagcccatcttcaagaagaccaaggagatcagattttccattgagaaagggattgct
ggtcaagtggcaagaacaggcgaggtcttgaacattccagatgcctacgcagaccctcgc
tttaacagggaggtggacctgtacacaggctacaccacgaggaacattctgtgtatgccc
atagtgagccgaggcagcgtgattggcgtggtgcagatggtgaacaagatcagcggtagc
gccttctccaagacagacgagaacaacttcaagatgtttgccgtcttctgcgcactggcc
ttgcactgtgctaacatgtaccacaggatccgccactcagagtgcatctacagggttacc
atggagaagctttcttaccacagcatctgcacctccgaggagtggcaaggcctcatgcgc
ttcaacctaccagcacgcatctgccgggacattgagctattccactttgacattggtcct
ttcgagaacatgtggcctgggatctttgtctacatgatccatcggtcttgtgggacatcc
tgttttgaacttgaaaaattgtgccgttttatcatgtctgtgaagaagaactatcggcgg
gttccttaccacaactggaagcatgcagtcacggtggcacactgcatgtatgccatactt
caaaacaacaatggcctcttcacagacctcgagcgcaaaggcctgctaattgcgtgtctg
tgccacgacctggaccacaggggcttcagtaacagctacctgcagaagttcgaccacccc
ctggcggcgctgtactccacttccaccatggagcaacaccacttctcccagacggtgtcc
atccttcagctggaagggcacaatatcttctccaccctgagctccagcgagtacgagcag
gtgctggagatcatccgcaaagccattatcgccactgacctcgccctatactttgggaac
aggaagcagttggaggagatgtaccagacagggtcgctgaacctccacaaccagtctcat
cgagaccgcgtcatcggcttgatgatgactgcctgcgatctttgctctgtgaccaaacta
tggccagttacaaaattgacagcgaatgatatatatgcagaattctgggctgagggtgat
gagatgaagaagctaggcatacagcccattcctatgatggacagagacaagcgagatgaa
gtccctcaagggcagcttggattctacaatgctgtggccattccctgctacaccaccttg
acgcagatcctcccacccacagagcctctgctgaaggcctgcagggataacctcagtcag
tgggagaaggtaattcggggagaagagacagcaatgtggatttcaggcccaggcccggcg
cctagcaagagcacatctgagaagctgaacgtgaaggttgacgactga
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