KEGG   Micromonospora cathayae: PVK37_20705
Entry
PVK37_20705       CDS       T10286                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mcay  Micromonospora cathayae
Pathway
mcay00270  Cysteine and methionine metabolism
mcay00450  Selenocompound metabolism
mcay00670  One carbon pool by folate
mcay01100  Metabolic pathways
mcay01110  Biosynthesis of secondary metabolites
mcay01230  Biosynthesis of amino acids
mcay04980  Cobalamin transport and metabolism
mcay04981  Folate transport and metabolism
Module
mcay_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mcay00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    PVK37_20705 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    PVK37_20705 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    PVK37_20705 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    PVK37_20705 (metH)
   04980 Cobalamin transport and metabolism
    PVK37_20705 (metH)
Enzymes [BR:mcay01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     PVK37_20705 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: WDZ82887
LinkDB
Position
complement(4569598..4573170)
AA seq 1190 aa
MRNSLSELRELLGQRIVVLDGAWGTMLQGAKLTPADYRGDRFTDHPLDVTGDPDLLNLTR
PDLILDVHRRYLAAGADITTTNTFTATSIGQADYGLESAVREMNVRGAQLARQAADEAGG
RFVAGSIGPLNVTLSLSPKVDDPAYRAVSFEQVRAAYAEQIAALVEGGVDLLMVETIFDT
LNAKAAIAAAREVAPDLPLWISVTIVDLSGRTLSGQTVEAFWTSIAHAEPLVVGMNCALG
AAEMRPHLAELSRLADTYVASHPNAGLPNAFGGYDQSPEESGELIAGFARDGMVNIVGGC
CGTTPAHIERIATAVAGLAPRELPARPAATRFSGLETFEIGPDTGFVMIGERTNVTGSAR
FRRLIEADDHQAAVDVALEQVRGGANLLDVNMDADLLDSERAMTTFLNLIATEPEVARIP
IMIDSSRWSVLEAGLKCVQGKGVVNSISLKEGEEPFLEQARRIREYGAGVVVMAFDEQGQ
ADTTERKVEICGRAYDLLIGSAGFDPEDIIFDPNVLAVATGIAEHNGYAKAFIDALPLIK
QRCPGARTSGGISNLSFSFRGNDVVREAMHSAFLLHAVRAGLDMGIVNAGQLAVYQDIPA
DLLELVEDVIFDRRPDATDRLVTFAGSVQGSGTRRTVDLSWREAPVRERLSHAMVHGIVD
FIEADTEEARQQADRPLEVIEGPLMDGMKIVGDLFGAGKMFLPQVVKSARVMKRAVAYLE
PFMEAEKAAGVGRGAGKVVLATVKGDVHDIGKNIVGVVLGCNNYEVIDLGVMVPAAKILD
VAVTEKADAVGLSGLITPSLDEMVTVAAEMQRRGLTLPLLIGGATTSRQHTAVRIAPAYD
GTTVHVLDASRVVGVVSDLLDADRAEKLDDENRVEQARLREQHEKRQRTPLLPLARARAN
RETVSFADLPVPAFTGVREVRPDLTTLREMIDWQFFFLAWELKGKYPAILEQPAARDLFA
DATALLDEIVATGALTAHGVYGFWPAHAEQDDLVVDGVRLPMLRQQTAKPDGRPNRCLAD
YVAPAGDHLGGFAVAVHGAEELAARYEAEHDDYRAIMVKALADRLAEAFAEWIHLTARRE
WYEPDAEPALADLHAERFRGIRPALGYPASPDHSLKQELFTLLDAERAGLGLTSSYAMTP
AAAVSALLFAHPASRYFTVGRIGDDQARDYAARRGLSYEEVEPWLRPNLG
NT seq 3573 nt   +upstreamnt  +downstreamnt
gtgcgaaattcgctgtcggagctgcgggaactgctgggccagcggatcgtggtgctggac
ggtgcgtggggcaccatgctccagggcgcgaagctcacgcccgccgactaccgcggtgac
cggttcaccgaccatccgctcgacgtcaccggtgacccggacctgctcaacctgacccgg
ccggacctcatcctggacgtgcaccgccggtatcttgccgccggcgccgacatcaccacc
accaacacgttcaccgcgaccagcatcggtcaggccgactacggtctggagtcggcggta
cgggagatgaacgtccgtggggcgcagctggcccgccaggccgccgacgaggccggcggg
cggttcgtggccggctcgatcggtccgctgaacgtcaccctgtcgttgtcgccgaaggtc
gacgacccggcctaccgggcggtctccttcgagcaggtgcgcgccgcgtacgccgagcag
atcgccgccctggtcgagggcggggtcgacctgctgatggtcgagacgatcttcgacacg
ctcaacgcgaaggcggcgatcgccgcggcccgcgaggtcgccccggacctgccgttgtgg
atctcggtgaccatcgtcgacctgagcgggcggaccctgtccgggcagaccgtcgaggcg
ttctggacgtcgatcgcgcacgccgagccgctggtggtcgggatgaactgcgcgctgggg
gcggcggagatgcgtccgcacctggccgagctgtcccggctggcggacacgtacgtcgcc
tcccaccccaacgccggcctgccgaacgcgttcggcggctacgaccagtccccggaggag
agcggggagctgatcgccgggttcgcccgggacgggatggtcaacatcgtcggtggctgc
tgcggtaccacgccggcgcacatcgagcggatcgccaccgcggtcgccgggctggccccg
cgtgagctgccggcccggccggccgcgacccggttcagcgggctggagaccttcgagatc
ggcccggacaccgggttcgtgatgatcggcgagcgcaccaacgtcaccggttcggcccgg
ttccgccggctgatcgaggccgacgaccaccaggcggccgtcgacgtggccctggagcag
gtccggggcggggcgaacctgctcgacgtcaacatggacgccgacctgctcgacagcgag
cgggcgatgaccaccttcctcaacctgatcgccaccgagcccgaggtggcccgcatcccc
atcatgatcgacagctcgcggtggagcgtgctggaggccgggctgaagtgcgtgcagggc
aagggcgtggtcaactcgatcagcctcaaggagggcgaggagccgttcctcgagcaggcc
cgccggatccgcgagtacggcgcgggcgtggtggtgatggccttcgacgagcagggccag
gccgacaccaccgaacgcaaggtggagatctgcggccgggcgtacgacctgctcatcggc
agtgccggcttcgaccccgaggacatcatcttcgacccgaacgtgctggccgtcgccacc
ggcatcgccgagcacaacgggtacgccaaggcgttcatcgacgcgctgccgctgatcaag
cagcgttgtccgggcgcgcggaccagcggcggcatctccaacctgtcgttctcgttccgg
ggcaacgacgtggtccgggaggcgatgcactcggcgttcctgctgcacgcggtccgggcc
gggctggacatgggcatcgtcaacgccggccagctcgccgtctaccaggacatcccggcc
gacctgctggagctcgtcgaggacgtgatcttcgaccggcggccggacgccaccgaccgg
ctggtcacgttcgccggcagcgtgcagggctcggggacccgccgcacggtggacctgtcc
tggcgggaggcgccggtacgggaacgcctgtcgcacgccatggtgcacggcatcgtcgac
ttcatcgaggccgacaccgaggaggcccggcagcaggccgaccgccccctggaggtgatc
gaggggccgctgatggacggcatgaagatcgtcggcgacctgttcggcgcggggaagatg
ttcctgccccaggtggtgaagagcgcccgggtgatgaagcgggcggtggcctacctggaa
ccgttcatggaggcggagaaggcggccggcgtcggacgcggggccggcaaagtggtgctg
gcgacggtcaagggcgacgtgcacgacatcggcaagaacatcgtcggggtggtgctcggc
tgcaacaactacgaggtgatcgacctcggcgtgatggtcccggccgcgaagatcctggac
gtcgcggtgaccgagaaggcggacgcggtcggcctgtccgggctgatcacgccgtcgctg
gacgagatggtcacggtcgccgccgagatgcagcgccgcgggctgaccctgccgctgctg
atcggtggggccaccacctcccggcagcacaccgccgtgcggatcgcgcccgcctacgac
ggcaccaccgtgcacgtgctggacgcctcccgggtggtcggggtggtgtccgacctgctg
gacgccgaccgcgccgagaagctggacgacgagaaccgggtcgagcaggcccggctgcgc
gagcagcacgagaagcgacagcggacgccgctgctgccgctggcacgggcccgcgccaac
cgggagacggtctccttcgccgacctgccggtgccggccttcaccggcgtacgcgaggtc
cggccggacctgaccacgctccgcgagatgatcgactggcagttcttcttcctggcctgg
gagctgaagggcaagtatccggcgatcctggaacagccggccgcccgggacctgttcgcc
gatgccaccgcgctgctggacgagatcgtcgccaccggcgcgctgaccgcccacggcgtg
tacggcttctggccggcgcacgccgagcaggacgacctggtggtcgacggggtccggctg
ccgatgctgcgtcagcagaccgccaagccggacggccggccgaaccgctgcctggccgac
tacgtcgccccggccggcgaccacctgggcgggttcgcggtggcggtgcacggcgcggag
gagctggccgcccggtacgaggccgagcacgacgactaccgggcgatcatggtgaaggcg
ctggccgaccggctcgccgaggcgttcgccgagtggatccacctgaccgcccgccgcgag
tggtacgagccggacgccgagccggcgctggcggacctgcacgccgaacggttccggggc
atccggccggcgctcggctacccggccagccccgaccacagcctcaagcaggagctgttc
acgctgctcgacgcggagcgggccgggctgggcctgaccagttcgtacgcgatgacgccg
gcggcggcggtcagcgcgctgctgttcgcccacccggcgtcgcggtacttcacggtgggc
cggatcggcgacgaccaggcccgcgactacgccgcccggcgcggcctgtcgtacgaggag
gtcgagccgtggctccggcccaacctgggctga

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