Macaca mulatta (rhesus monkey): 574322
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Entry
574322 CDS
T01028
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00140
Steroid hormone biosynthesis
mcc00980
Metabolism of xenobiotics by cytochrome P450
mcc01100
Metabolic pathways
mcc05204
Chemical carcinogenesis - DNA adducts
Module
mcc_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
574322 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
574322 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
574322 (HSD11B1)
Enzymes [BR:
mcc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
574322 (HSD11B1)
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Gene cluster
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
2-Hacid_dh_C
Pyr_redox_3
Pyr_redox_2
Shikimate_DH
NAD_binding_2
AdoHcyase_NAD
Motif
Other DBs
NCBI-GeneID:
574322
NCBI-ProteinID:
NP_001182354
Ensembl:
ENSMMUG00000040879
UniProt:
F6SQD2
A0A8J8XJM0
LinkDB
All DBs
Position
1:67209536..67239875
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AA seq
292 aa
AA seq
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MAFMKKYLLPILGLFMAYYYYSAYEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV
AAYSASKFALDGFFSSIRKEYSVAKVNVSITLCVLGLIDTDTAMKAVSGIINMQAAPKEE
CALEIIKGGALRQEEVYYDSSLWTTLLMRNPCRKILEFLYLPSYNMDRFTKN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctcctccccattctggggctcttcatggcctactactac
tattctgcatatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaagggattggaagagagatggcttatcatctggcgaagatgggagcccac
gtggtggtaacagcgaggtcaaaagaaactctacagaaggtggtttcccactgcctggaa
cttggagcagcctcagcacactacattgctggcaccatggaagacatgaccttcgcagag
caatttgttgcccaagcaggaaagctcatgggaggactagacatgctcattctcaaccac
atcaccaacacttctttgaatctttttcatgatgatattcaccatgtgcgcaaaagcatg
gaggtcaacttcctcagttatgtggtcctgactgtagctgccttgcccatgctgaagcag
agcaatggaagcattgttgtcgtctcttctttggctgggaaagtggcttatccaatggtt
gctgcctattctgcaagcaagtttgctttggatgggttcttctcctccatcagaaaggaa
tattcagtggccaaggtcaatgtatcaatcactctctgtgttcttggcctcatagacaca
gacacagccatgaaggcagtttctgggataatcaatatgcaagcagctccaaaggaggaa
tgtgcccttgagatcatcaaagggggagctctgcgtcaagaagaagtatattatgacagc
tcactctggaccactcttctgatgagaaatccatgcaggaagatcctggaatttctctac
ttaccgagctataatatggacagattcacaaaaaactag
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