Macaca mulatta (rhesus monkey): 711382
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Entry
711382 CDS
T01028
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc01524
Platinum drug resistance
mcc04010
MAPK signaling pathway
mcc04071
Sphingolipid signaling pathway
mcc04141
Protein processing in endoplasmic reticulum
mcc04210
Apoptosis
mcc04530
Tight junction
mcc04668
TNF signaling pathway
mcc04714
Thermogenesis
mcc04722
Neurotrophin signaling pathway
mcc04932
Non-alcoholic fatty liver disease
mcc04936
Alcoholic liver disease
mcc05010
Alzheimer disease
mcc05012
Parkinson disease
mcc05014
Amyotrophic lateral sclerosis
mcc05016
Huntington disease
mcc05017
Spinocerebellar ataxia
mcc05022
Pathways of neurodegeneration - multiple diseases
mcc05208
Chemical carcinogenesis - reactive oxygen species
mcc05417
Lipid and atherosclerosis
mcc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
711382 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
711382 (MAP3K5)
04668 TNF signaling pathway
711382 (MAP3K5)
04071 Sphingolipid signaling pathway
711382 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
711382 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
711382 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
711382 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
711382 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
711382 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
711382 (MAP3K5)
05012 Parkinson disease
711382 (MAP3K5)
05014 Amyotrophic lateral sclerosis
711382 (MAP3K5)
05016 Huntington disease
711382 (MAP3K5)
05017 Spinocerebellar ataxia
711382 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
711382 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
711382 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
711382 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
711382 (MAP3K5)
04932 Non-alcoholic fatty liver disease
711382 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
711382 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
711382 (MAP3K5)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
711382 (MAP3K5)
Protein kinases [BR:
mcc01001
]
Serine/threonine kinases: STE group
STE11 family
711382 (MAP3K5)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
711382
NCBI-ProteinID:
XP_002803972
Ensembl:
ENSMMUG00000016376
UniProt:
I0FRT6
LinkDB
All DBs
Position
4:complement(40187527..40431026)
Genome browser
AA seq
1374 aa
AA seq
DB search
MSTEAGEGITFSVPPFAPSGFCTIPEGGICRRGGAAAVGESEEHQLPPPPPGSFWNVESA
AAPGIGCPAATSASSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREAC
ETVGATLETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANN
IILYCDTNSDSLQSLKELICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQP
NFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIR
QRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALN
RRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFK
KAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGF
FLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVD
FWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIH
EWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRS
TEEGDCESDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQ
PLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTI
GFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFT
GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVH
PEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNE
YLRSISLPVPVLVEDTSSSSEYGSVSPDTELKADPFSFKTRAKSCGERDVKGIRTLFLGI
PDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGSEEP
KLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNK
VLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDVEDDHEE
QPSNQTVRRPQPVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELV
RKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSPGTNTEDSELTDWLRVN
GADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQT
NT seq
4125 nt
NT seq
+upstream
nt +downstream
nt
atgagcacggaggcgggcgagggcatcactttctccgtgccacccttcgccccctcgggc
ttctgcaccattcccgagggcggcatctgcaggaggggaggagcggcggcggtgggcgag
agcgaggagcaccagctgccaccgccgccgccgggcagcttctggaacgtggagagcgcc
gccgccccaggcatcgggtgtcccgcggccacctccgcgagcagtgccacccgaggccgg
ggcagctctgttggcgggggcagccgacggaccacggtggcatatgtgatcaacgaagcg
agccaggggcaactggtggtggccgagagcgaggccctgcagagcttgcgggaggcgtgc
gagacggtgggcgccaccctggaaaccctgcattttgggaaactcgactttggtgaaacc
accgtcctggaccgcttttacaatgcagatattgcggtggtggagatgagcgatgccttc
cggcaaccgtccttgttttaccaccttggggtgagagaaagtttcagcatggccaacaac
atcatcctctactgtgatactaactcggactctctgcagtcgctgaaggaactcatttgc
cagaagaatactatgtgcactgggaactacacctttgttccttatatgataacgccacat
aacaaggtctactgctgtgacagcagcttcatgaaggggttgacagagctcatgcaaccg
aacttcgagctgcttcttggacccatctgcttacctcttgtggatcgttttattcaactt
ttgaaggtggcacaagcaagttctagccagtatttccgggaatctatactcaatgatatc
aggaaagctcgtaatttatacactggtaaagaattggcagctgagttggcaagaattcgg
cagcgagtagataatatcgaagtcttgacagcagatattgtcataaatctgttactttcc
tacagagatatccaggactatgattctattgtgaagctggtagagactttagaaaaactg
ccaacctttgatttggcctcccatcaccatgtgaagtttcattatgcatttgcactgaat
aggagaaatctccctggagacagagcaaaagctcttgatattatgattcccatggtgcaa
agtgaaggacaagttgcttcagatatgtattgcctagttggtcgaatctacaaagatatg
tttttggactctaatttcacagacacggaaagcagagaccatggagcttcttggttcaaa
aaggcatttgaatctgagccaacactacagtcaggaattaattatgcggtcctcctcctg
gcagctgggcaccagtttgaatcttcctttgagctccggaaagttggggtgaagctaagt
agtcttcttggtaaaaagggaaacttggagaaactccagagctactgggaagttggattt
tttctgggggccagtgtcctagccaatgaccacatgagagtcattcaagcatctgaaaag
ctttttaaactgaagacaccagcgtggtacctcaagtctattgtagagacaattttgata
tataagcattttgtgaaactgaccacagaacagcctgtggccaagcaagaacttgtggac
ttttggatggatttcctggtcgaggccacaaagaccgatgttactgtggttaggtttcca
gtattaatattagaaccaaccaaaatctatcaaccttcttatttgtctatcaacaatgaa
gttgaggaaaagacaatctctatttggcacgtgcttcctgatgacaagaaaggtatacat
gagtggaattttagtgcctcttctgtcaggggagtgagtatttctaaatttgaagaaaga
tgctgctttctttatgtgctccacaattctgatgatttccaaatctatttctgtacagaa
cttcattgtaaaaagttttttgagatggtgaacaccattaccgaagagaaggggagaagc
acagaggaaggagactgtgaaagtgactcgctggagtatgactatgaatatgatgaaaat
ggtgacagagtcgttttaggaaaaggcacttacgggatagtctacgcaggtcgggacttg
agcaaccaagtcagaattgctattaaggaaatcccagagagagacagcagatactctcag
cccctgcatgaagaaatagcattgcataagcacctgaagcacaaaaatattgtccagtat
ctgggctctttcagtgagaatggtttcattaaaatcttcatggagcaggtccctggagga
agtctttctgctctccttcgttccaaatggggtccattaaaagataatgagcaaacaatt
ggcttttatacaaagcaaatactggaaggattaaaatatctccatgacaatcagatagtt
caccgcgacataaagggtgacaatgtgttgattaatacctacagtggtgttctcaagatc
tctgacttcgggacatcaaagaggcttgctggcataaacccctgtactgaaacttttact
ggtaccctccagtatatggcaccagaaataatagataaaggaccaagaggctatggaaaa
gcagcagacatctggtctctgggctgtacaatcatcgaaatggccacaggaaaaccccca
ttttatgaactgggagaaccacaagcagctatgttcaaggtgggaatgtttaaagtccac
cctgagatcccagaatccatgtctgcagaggccaaggcattcatcctgaaatgttttgaa
ccagaccctgacaagagagcctgtgctaacgacttgcttgttgatgagtttttaaaagtt
tcaagcaaaaagaaaaagacacaacctaagctttcagctctttcagctggatcaaatgaa
tatctcaggagtatatctttgccagtacctgtgctggtggaggacaccagcagcagcagt
gagtacggctcagtttcacccgacacggagttgaaagcggaccccttctctttcaaaaca
agagccaaatcctgcggagaaagagatgtcaagggaattcggacactctttttgggcatt
ccagatgagaattttgaagatcacagtgctcccccttcccctgaagaaaaagattccgga
ttcttcatgctgaggaaggacagtgagaggcgagccacccttcacaggatcctgacagaa
gaccaagacaaagttgtgagaaatctaatggaatctttagctcaggggtctgaagaaccc
aaactaaaatgggaacacatcacaaccctcattgcaagcctcagagaatttgtgagatcc
actgaccgaaaaatcatagccaccacattgtcaaagctgaaactggagctggacttcgac
agccatggcattagccaagtccaggtggtgctctttggttttcaagatgctgtcaataaa
gttcttcggaatcataacatcaagccgcactggatgtttgccttagacagtatcatccgg
aaggcggtgcagacagccattaccatcctggttccagaactaaggccacatttcagcctt
gcatctgagagtgatactgctgatcaagaagacttggatgtagaagatgaccatgaggaa
cagccttcaaatcaaactgtccgaagacctcagcctgtcattgaagatgccgtggctacc
tcaggcgtgagcacgcttagttctactgtgtctcatgattcccagagtgctcaccggtca
ctgaatgtacagcttggaaggatgaaaatagaaaccaatagattactggaagaattggtt
cggaaagagaaggaattacaagcactccttcatcgagctattgaagaaaaagaccaagaa
attaaacacctgaagcttaagtcccaacccatagaaattcctgaactgcctgtatttcac
ctaaattctcctggcacaaatactgaagattctgagcttaccgactggctgagagtgaat
ggagcggatgaagacactataagccggtttttggctgaagattatacactattggatgtt
ctctactatgttacacgtgatgacttaaaatgcttgagactaaggggagggatgctgtgc
acactgtggaaggccatcattgactttcgaaacaaacagacttga
DBGET
integrated database retrieval system
