Macaca mulatta (rhesus monkey): 715897 Help Entry 715897            CDS       T01028                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc00230   Purine metabolism mcc01100   Metabolic pathways mcc01522   Endocrine resistance mcc04015   Rap1 signaling pathway mcc04022   cGMP-PKG signaling pathway mcc04024   cAMP signaling pathway mcc04062   Chemokine signaling pathway mcc04072   Phospholipase D signaling pathway mcc04081   Hormone signaling mcc04082   Neuroactive ligand signaling mcc04114   Oocyte meiosis mcc04211   Longevity regulating pathway mcc04213   Longevity regulating pathway - multiple species mcc04261   Adrenergic signaling in cardiomyocytes mcc04270   Vascular smooth muscle contraction mcc04371   Apelin signaling pathway mcc04540   Gap junction mcc04611   Platelet activation mcc04713   Circadian entrainment mcc04714   Thermogenesis mcc04723   Retrograde endocannabinoid signaling mcc04724   Glutamatergic synapse mcc04725   Cholinergic synapse mcc04726   Serotonergic synapse mcc04727   GABAergic synapse mcc04728   Dopaminergic synapse mcc04750   Inflammatory mediator regulation of TRP channels mcc04911   Insulin secretion mcc04912   GnRH signaling pathway mcc04913   Ovarian steroidogenesis mcc04914   Progesterone-mediated oocyte maturation mcc04915   Estrogen signaling pathway mcc04916   Melanogenesis mcc04918   Thyroid hormone synthesis mcc04921   Oxytocin signaling pathway mcc04923   Regulation of lipolysis in adipocytes mcc04924   Renin secretion mcc04925   Aldosterone synthesis and secretion mcc04926   Relaxin signaling pathway mcc04927   Cortisol synthesis and secretion mcc04928   Parathyroid hormone synthesis, secretion and action mcc04934   Cushing syndrome mcc04935   Growth hormone synthesis, secretion and action mcc04970   Salivary secretion mcc04971   Gastric acid secretion mcc04972   Pancreatic secretion mcc04976   Bile secretion mcc05012   Parkinson disease mcc05030   Cocaine addiction mcc05031   Amphetamine addiction mcc05032   Morphine addiction mcc05034   Alcoholism mcc05163   Human cytomegalovirus infection mcc05166   Human T-cell leukemia virus 1 infection mcc05200   Pathways in cancer mcc05207   Chemical carcinogenesis - receptor activation mcc05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mcc00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     715897 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     715897 (ADCY5)    04072 Phospholipase D signaling pathway     715897 (ADCY5)    04024 cAMP signaling pathway     715897 (ADCY5)    04022 cGMP-PKG signaling pathway     715897 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     715897 (ADCY5)    04081 Hormone signaling     715897 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     715897 (ADCY5)    04062 Chemokine signaling pathway     715897 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     715897 (ADCY5)    04923 Regulation of lipolysis in adipocytes     715897 (ADCY5)    04913 Ovarian steroidogenesis     715897 (ADCY5)    04915 Estrogen signaling pathway     715897 (ADCY5)    04921 Oxytocin signaling pathway     715897 (ADCY5)    04926 Relaxin signaling pathway     715897 (ADCY5)    04935 Growth hormone synthesis, secretion and action     715897 (ADCY5)    04918 Thyroid hormone synthesis     715897 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     715897 (ADCY5)    04924 Renin secretion     715897 (ADCY5)    04925 Aldosterone synthesis and secretion     715897 (ADCY5)    04927 Cortisol synthesis and secretion     715897 (ADCY5)   09154 Digestive system    04970 Salivary secretion     715897 (ADCY5)    04971 Gastric acid secretion     715897 (ADCY5)    04972 Pancreatic secretion     715897 (ADCY5)    04976 Bile secretion     715897 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     715897 (ADCY5)    04727 GABAergic synapse     715897 (ADCY5)    04725 Cholinergic synapse     715897 (ADCY5)    04728 Dopaminergic synapse     715897 (ADCY5)    04726 Serotonergic synapse     715897 (ADCY5)    04723 Retrograde endocannabinoid signaling     715897 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     715897 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     715897 (ADCY5)    04213 Longevity regulating pathway - multiple species     715897 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     715897 (ADCY5)    04714 Thermogenesis     715897 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     715897 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     715897 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     715897 (ADCY5)    05163 Human cytomegalovirus infection     715897 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     715897 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     715897 (ADCY5)    05031 Amphetamine addiction     715897 (ADCY5)    05032 Morphine addiction     715897 (ADCY5)    05034 Alcoholism     715897 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     715897 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     715897 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     715897 (ADCY5) Enzymes [BR:mcc01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      715897 (ADCY5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC HILPDA Motif Other DBs NCBI-GeneID:  715897 NCBI-ProteinID:  XP_014985498 Ensembl:  ENSMMUG00000002230 UniProt:  A0A1D5QWQ7 LinkDB All DBs Position 2:152870248..153034691 Genome browser AA seq 1263 aa AA seqDB search MSSSKSVSPPGYAAQKTAAPAPRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA VTPQQQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQ RRGAAGGGSTRAPPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAV EGGEESGDGGSSADSGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLN QSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHM GLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLS ALHLVIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQAR LHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGF TSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCV EMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAG GKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAK MNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDE FLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFV QITIVPHSVFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVG VFTITLVFLAAFVNMFTCNSKDLLGCLAQEHNISASQVNACHVVESAVNYSLGDEQGFCG SPWPNCNFPEYFTYSVLLSLLACSVFLQINCIGKLALMLAIELIYVLIVEVPGVTLFDNA DLLVTANAIDFFNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLW KLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIA NFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDS TYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDI WGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGP PLS NT seq 3792 nt NT seq  +upstreamnt  +downstreamnt atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagaagactgcggcgccg gcgccccggggaggccccgaacaccgctcggcgtggggcgaggccgattcccgcgcgaat ggctacccccatgcccccgggggttctgcccgcggctccaccaagaaacccgggggggcg gtgaccccgcagcagcagcagcagcagcgcctggccagccgctggcgcagcgacgacgac gacgatcctccgctgagtggcgacgatcccctggccgggggcttcggcttcagcttccgc tccaagtccgcctggcaggagcgcggcggcgacgactgcggtcgcggcagccgccggcaa cggcggggcgcggccggcgggggcagcacccgggcgccccctgcgggcggcggcggcggc tcggcggcggcggctgcctcggcgggcgggacggaggtgcgccctcgctcggtggaggtg ggcctggaggagcggcggggcaaggggcgcgcggccgacgagctggaggccggcgccgtc gagggcggcgaggagtccggggatggcggtagttcggcagactcgggctcgggcgcgggg cccggcgcggtgctgtccctgggcgcctgctgcctggcgttgctgcagatattccgctcc aagaagttcccgtcggacaaactggagcggctgtaccagcgctacttcttccgcctgaac cagagcagcctcaccatgctcatggccgtgctggtgctcgtgtgcctggtcatgttggcc ttccacgcggcgcggcccccgctccagctgccctacctggccgtgctggcggccgccgtg ggcgtcatcctcatcatggctgtgctctgcaaccgcgccgccttccaccaggaccacatg ggcctggcctgctatgcgctcatcgccgtggtgctggccgtccaggtggtgggcctgctg ctgccgcagccgcgcagcgcctctgagggcatctggtggaccgtgttcttcatctacacc atctacacgctgctgcccgtgcgcatgcgggccgcggtgctcagcggggtgctcctgtcc gccctccacctggtcatcgccctgcgcaccaacgcccaggaccagttcctgctcaagcag cttgtctccaatgttctcattttctcctgcaccaacatcgtgggtgtctgcacccactac ccagctgaggtctcccagagacaggctttccaggagacccgagagtgcatccaggcgcgg ctccactcacagcgggagaaccagcaacaggagcggctcctgctgtctgtccttccccgt catgttgccatggagatgaaagcagacatcaacgccaagcaggaggatatgatgttccat aagatttacatccagaaacatgacaacgtgagcatcctgtttgctgacatcgagggcttc accagcctggcatcccagtgcaccgcacaggaactggtcatgaccctcaacgagctcttc gcccgcttcgacaagctggccgcagagaatcactgtttacgtattaagatcctcggggat tgttattactgcgtctcggggcttcctgaagcaagggctgaccacgcccactgctgcgtg gagatgggcatggacatgatcgaggccatctcgttggtccgggaggtgacaggggtgaac gtgaacatgcgtgtgggaattcacagcgggcgagtacactgcggtgtccttggtctaagg aagtggcagttcgacgtctggtctaacgacgtcacgctagccaaccacatggaggctggc ggcaaggcgggacgcatccacatcaccaaggctacactcaactacctgaacggggactac gaggtggagccaggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgag accttcctcatcctgcgctgcacccagaagcggaaagaagagaaggccatgatcgccaag atgaaccgccagagaaccaactccatcgggcacaacccacctcactggggggctgagcgc cccttctacaaccacctgggtggcaaccaggtgtccaaggagatgaagcggatgggcttt gaagaccccaaggacaagaatgcccaggagagtgcaaaccctgaggatgaagtggatgag tttctgggccgcgccattgacgccaggagcattgacaggcttcggtctgagcacgtccgc aagttcctcctgaccttcagggagcctgacttagagaagaagtactccaagcaggtagac gaccgatttggtgcctatgtggcgtgtgcctcgctcgtcttcctcttcatctgctttgtc cagatcaccatcgtgccccactctgtattcatgctcagcttctacctgacctgttccctg ctgctgaccttggtggtgtttgtgtctgtgatctactcctgcgtaaagctcttcccctcc ccgctgcagactctctccaggaagatcgtgcggtccaagatgaacagcaccctggttggg gtgttcaccatcaccctggtgttcctggcagcttttgtcaacatgttcacatgcaactcc aaggacctgctgggctgcttggcacaggagcacaacatcagcgcaagccaggtcaacgca tgtcatgtggtggagtcggccgtcaactacagcctgggcgatgagcagggcttctgtggc agcccctggcccaactgcaacttccccgagtacttcacctacagcgtgctgctcagcctg ctggcctgctccgtgttcctgcagatcaactgcatcgggaagctggcgctcatgctggcc atcgagctcatctacgtgctcatcgtggaggtgccgggtgtcacgctcttcgacaatgcc gacctgctggtcaccgccaatgccatagacttcttcaacaacgggacctcccagtgccct gagcacgcaaccaaggtggcattgaaggtggtgacgcccatcatcatctcagtctttgtg ctggccctgtacctgcacgcccagcaggtggagtccactgcccgcctcgacttcctctgg aaactgcaggccacagaggagaaggaggagatggaggagctgcaggcctacaaccggcgg ctgctgcacaacatcctgcccaaggatgtggccgctcacttcctggcccgcgagcggcgc aacgatgagctctactatcagtcctgtgagtgcgtggcggtcatgttcgcctccatcgcc aacttctccgaattctacgttgagctggaggccaacaacgagggtgtcgagtgcctgcgg ctactcaatgagatcatcgctgactttgatgagatcatcagcgaggatcggttccggcag ctggagaagatcaagaccatcggcagcacctacatggctgcctccggcctcaacgactcc acctacgacaaggtgggcaagacccacatcaaggcactggccgactttgccatgaagctg atggaccagatgaagtacatcaatgagcactctttcaacaacttccagatgaagatcggg ctcaacatcggccccgtggtggccggggtgataggggcacgaaagcctcagtacgacatc tggggcaataccgtgaacgtggccagccgcatggacagcactggtgtacctgaccgcatc caggtcaccacggacatgtaccaggtgctggccgccaacacataccaactggagtgccgg ggcgtggtcaaggtcaagggcaaaggcgagatgatgacctacttcctcaatggagggccc ccgctcagttag

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