Macaca mulatta (rhesus monkey): 719367
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Entry
719367 CDS
T01028
Symbol
PIK3R2
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit beta
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc01521
EGFR tyrosine kinase inhibitor resistance
mcc01522
Endocrine resistance
mcc01524
Platinum drug resistance
mcc04012
ErbB signaling pathway
mcc04014
Ras signaling pathway
mcc04015
Rap1 signaling pathway
mcc04024
cAMP signaling pathway
mcc04062
Chemokine signaling pathway
mcc04066
HIF-1 signaling pathway
mcc04068
FoxO signaling pathway
mcc04070
Phosphatidylinositol signaling system
mcc04071
Sphingolipid signaling pathway
mcc04072
Phospholipase D signaling pathway
mcc04081
Hormone signaling
mcc04140
Autophagy - animal
mcc04150
mTOR signaling pathway
mcc04151
PI3K-Akt signaling pathway
mcc04152
AMPK signaling pathway
mcc04210
Apoptosis
mcc04211
Longevity regulating pathway
mcc04213
Longevity regulating pathway - multiple species
mcc04218
Cellular senescence
mcc04360
Axon guidance
mcc04370
VEGF signaling pathway
mcc04380
Osteoclast differentiation
mcc04510
Focal adhesion
mcc04550
Signaling pathways regulating pluripotency of stem cells
mcc04611
Platelet activation
mcc04613
Neutrophil extracellular trap formation
mcc04620
Toll-like receptor signaling pathway
mcc04625
C-type lectin receptor signaling pathway
mcc04630
JAK-STAT signaling pathway
mcc04650
Natural killer cell mediated cytotoxicity
mcc04660
T cell receptor signaling pathway
mcc04662
B cell receptor signaling pathway
mcc04664
Fc epsilon RI signaling pathway
mcc04666
Fc gamma R-mediated phagocytosis
mcc04668
TNF signaling pathway
mcc04670
Leukocyte transendothelial migration
mcc04722
Neurotrophin signaling pathway
mcc04725
Cholinergic synapse
mcc04750
Inflammatory mediator regulation of TRP channels
mcc04810
Regulation of actin cytoskeleton
mcc04910
Insulin signaling pathway
mcc04914
Progesterone-mediated oocyte maturation
mcc04915
Estrogen signaling pathway
mcc04917
Prolactin signaling pathway
mcc04919
Thyroid hormone signaling pathway
mcc04923
Regulation of lipolysis in adipocytes
mcc04926
Relaxin signaling pathway
mcc04929
GnRH secretion
mcc04930
Type II diabetes mellitus
mcc04931
Insulin resistance
mcc04932
Non-alcoholic fatty liver disease
mcc04933
AGE-RAGE signaling pathway in diabetic complications
mcc04935
Growth hormone synthesis, secretion and action
mcc04960
Aldosterone-regulated sodium reabsorption
mcc04973
Carbohydrate digestion and absorption
mcc05010
Alzheimer disease
mcc05017
Spinocerebellar ataxia
mcc05020
Prion disease
mcc05100
Bacterial invasion of epithelial cells
mcc05135
Yersinia infection
mcc05142
Chagas disease
mcc05146
Amoebiasis
mcc05160
Hepatitis C
mcc05161
Hepatitis B
mcc05162
Measles
mcc05163
Human cytomegalovirus infection
mcc05164
Influenza A
mcc05165
Human papillomavirus infection
mcc05166
Human T-cell leukemia virus 1 infection
mcc05167
Kaposi sarcoma-associated herpesvirus infection
mcc05168
Herpes simplex virus 1 infection
mcc05169
Epstein-Barr virus infection
mcc05170
Human immunodeficiency virus 1 infection
mcc05171
Coronavirus disease - COVID-19
mcc05200
Pathways in cancer
mcc05203
Viral carcinogenesis
mcc05205
Proteoglycans in cancer
mcc05206
MicroRNAs in cancer
mcc05207
Chemical carcinogenesis - receptor activation
mcc05208
Chemical carcinogenesis - reactive oxygen species
mcc05210
Colorectal cancer
mcc05211
Renal cell carcinoma
mcc05212
Pancreatic cancer
mcc05213
Endometrial cancer
mcc05214
Glioma
mcc05215
Prostate cancer
mcc05218
Melanoma
mcc05220
Chronic myeloid leukemia
mcc05221
Acute myeloid leukemia
mcc05222
Small cell lung cancer
mcc05223
Non-small cell lung cancer
mcc05224
Breast cancer
mcc05225
Hepatocellular carcinoma
mcc05226
Gastric cancer
mcc05230
Central carbon metabolism in cancer
mcc05231
Choline metabolism in cancer
mcc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mcc05415
Diabetic cardiomyopathy
mcc05417
Lipid and atherosclerosis
mcc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
719367 (PIK3R2)
04014 Ras signaling pathway
719367 (PIK3R2)
04015 Rap1 signaling pathway
719367 (PIK3R2)
04370 VEGF signaling pathway
719367 (PIK3R2)
04630 JAK-STAT signaling pathway
719367 (PIK3R2)
04668 TNF signaling pathway
719367 (PIK3R2)
04066 HIF-1 signaling pathway
719367 (PIK3R2)
04068 FoxO signaling pathway
719367 (PIK3R2)
04070 Phosphatidylinositol signaling system
719367 (PIK3R2)
04072 Phospholipase D signaling pathway
719367 (PIK3R2)
04071 Sphingolipid signaling pathway
719367 (PIK3R2)
04024 cAMP signaling pathway
719367 (PIK3R2)
04151 PI3K-Akt signaling pathway
719367 (PIK3R2)
04152 AMPK signaling pathway
719367 (PIK3R2)
04150 mTOR signaling pathway
719367 (PIK3R2)
09133 Signaling molecules and interaction
04081 Hormone signaling
719367 (PIK3R2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
719367 (PIK3R2)
09143 Cell growth and death
04210 Apoptosis
719367 (PIK3R2)
04218 Cellular senescence
719367 (PIK3R2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
719367 (PIK3R2)
04550 Signaling pathways regulating pluripotency of stem cells
719367 (PIK3R2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
719367 (PIK3R2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
719367 (PIK3R2)
04613 Neutrophil extracellular trap formation
719367 (PIK3R2)
04620 Toll-like receptor signaling pathway
719367 (PIK3R2)
04625 C-type lectin receptor signaling pathway
719367 (PIK3R2)
04650 Natural killer cell mediated cytotoxicity
719367 (PIK3R2)
04660 T cell receptor signaling pathway
719367 (PIK3R2)
04662 B cell receptor signaling pathway
719367 (PIK3R2)
04664 Fc epsilon RI signaling pathway
719367 (PIK3R2)
04666 Fc gamma R-mediated phagocytosis
719367 (PIK3R2)
04670 Leukocyte transendothelial migration
719367 (PIK3R2)
04062 Chemokine signaling pathway
719367 (PIK3R2)
09152 Endocrine system
04910 Insulin signaling pathway
719367 (PIK3R2)
04923 Regulation of lipolysis in adipocytes
719367 (PIK3R2)
04929 GnRH secretion
719367 (PIK3R2)
04915 Estrogen signaling pathway
719367 (PIK3R2)
04914 Progesterone-mediated oocyte maturation
719367 (PIK3R2)
04917 Prolactin signaling pathway
719367 (PIK3R2)
04926 Relaxin signaling pathway
719367 (PIK3R2)
04935 Growth hormone synthesis, secretion and action
719367 (PIK3R2)
04919 Thyroid hormone signaling pathway
719367 (PIK3R2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
719367 (PIK3R2)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
719367 (PIK3R2)
09156 Nervous system
04725 Cholinergic synapse
719367 (PIK3R2)
04722 Neurotrophin signaling pathway
719367 (PIK3R2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
719367 (PIK3R2)
09158 Development and regeneration
04360 Axon guidance
719367 (PIK3R2)
04380 Osteoclast differentiation
719367 (PIK3R2)
09149 Aging
04211 Longevity regulating pathway
719367 (PIK3R2)
04213 Longevity regulating pathway - multiple species
719367 (PIK3R2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
719367 (PIK3R2)
05206 MicroRNAs in cancer
719367 (PIK3R2)
05205 Proteoglycans in cancer
719367 (PIK3R2)
05207 Chemical carcinogenesis - receptor activation
719367 (PIK3R2)
05208 Chemical carcinogenesis - reactive oxygen species
719367 (PIK3R2)
05203 Viral carcinogenesis
719367 (PIK3R2)
05230 Central carbon metabolism in cancer
719367 (PIK3R2)
05231 Choline metabolism in cancer
719367 (PIK3R2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
719367 (PIK3R2)
09162 Cancer: specific types
05210 Colorectal cancer
719367 (PIK3R2)
05212 Pancreatic cancer
719367 (PIK3R2)
05225 Hepatocellular carcinoma
719367 (PIK3R2)
05226 Gastric cancer
719367 (PIK3R2)
05214 Glioma
719367 (PIK3R2)
05221 Acute myeloid leukemia
719367 (PIK3R2)
05220 Chronic myeloid leukemia
719367 (PIK3R2)
05218 Melanoma
719367 (PIK3R2)
05211 Renal cell carcinoma
719367 (PIK3R2)
05215 Prostate cancer
719367 (PIK3R2)
05213 Endometrial cancer
719367 (PIK3R2)
05224 Breast cancer
719367 (PIK3R2)
05222 Small cell lung cancer
719367 (PIK3R2)
05223 Non-small cell lung cancer
719367 (PIK3R2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
719367 (PIK3R2)
05170 Human immunodeficiency virus 1 infection
719367 (PIK3R2)
05161 Hepatitis B
719367 (PIK3R2)
05160 Hepatitis C
719367 (PIK3R2)
05171 Coronavirus disease - COVID-19
719367 (PIK3R2)
05164 Influenza A
719367 (PIK3R2)
05162 Measles
719367 (PIK3R2)
05168 Herpes simplex virus 1 infection
719367 (PIK3R2)
05163 Human cytomegalovirus infection
719367 (PIK3R2)
05167 Kaposi sarcoma-associated herpesvirus infection
719367 (PIK3R2)
05169 Epstein-Barr virus infection
719367 (PIK3R2)
05165 Human papillomavirus infection
719367 (PIK3R2)
09171 Infectious disease: bacterial
05135 Yersinia infection
719367 (PIK3R2)
05100 Bacterial invasion of epithelial cells
719367 (PIK3R2)
09174 Infectious disease: parasitic
05146 Amoebiasis
719367 (PIK3R2)
05142 Chagas disease
719367 (PIK3R2)
09164 Neurodegenerative disease
05010 Alzheimer disease
719367 (PIK3R2)
05017 Spinocerebellar ataxia
719367 (PIK3R2)
05020 Prion disease
719367 (PIK3R2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
719367 (PIK3R2)
05418 Fluid shear stress and atherosclerosis
719367 (PIK3R2)
05415 Diabetic cardiomyopathy
719367 (PIK3R2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
719367 (PIK3R2)
04932 Non-alcoholic fatty liver disease
719367 (PIK3R2)
04931 Insulin resistance
719367 (PIK3R2)
04933 AGE-RAGE signaling pathway in diabetic complications
719367 (PIK3R2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
719367 (PIK3R2)
01524 Platinum drug resistance
719367 (PIK3R2)
01522 Endocrine resistance
719367 (PIK3R2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mcc04131
]
719367 (PIK3R2)
Membrane trafficking [BR:
mcc04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
719367 (PIK3R2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
RhoGAP
SH3_1
SH2_1
SH3_9
Ribosomal_L22e
SH3_2
Motif
Other DBs
NCBI-GeneID:
719367
NCBI-ProteinID:
NP_001244981
Ensembl:
ENSMMUG00000003162
UniProt:
F7EP57
LinkDB
All DBs
Position
19:17676293..17695959
Genome browser
AA seq
727 aa
AA seq
DB search
MAGPEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQALGVAEGGERCPQNVGWMPGL
NERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPRDGAPEPGLTLPDLPEQFSP
PDVAPPLLVKLVEAIERTGLDSESHYRPELPTPRTDWTLSDVDQWDVTALADGIKSFLLA
LPAPLVTPEASAEARRALREAAGPVGPALEPPTLPLHRALTLRFLLQHLGRVARRAPALG
PAVRALGATFGPLLLRAPPPSSPPPGGAPDGSEPSPDFPALLVEKLLQEHLEEQEVAPPA
LPPKPPKAKLAPAGLANGGSPPSLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKI
QGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRL
LYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAI
EAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTK
LEQQLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNET
EDQYALMEDEDDLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVV
DGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGP
GPPPAAR
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atggcgggccctgagggtttccagtaccgcgctctgtacccgttccgccgggagcggcca
gaggacctggagctgctgcctggcgatgtgctggtagtgagccgggcggccttgcaggca
ctgggtgtggccgagggtggcgagcgctgcccacagaatgtgggctggatgcccggcctc
aacgagcgcacacggcagcgaggtgacttccctggcacctacgtcgagttcctggggccc
gtggccctggcccggcctggccctcgcccacggggcccccgcccactgcccgccaggccc
cgtgatggggcccctgagccaggcctcacactccccgacttgcctgagcagttctcccca
cccgatgtggcaccccctcttctggtgaagcttgtggaggccattgaaaggacagggctg
gacagcgaatctcactaccggccggagctgcccacaccgcgtacagactggaccctgagc
gacgtggaccagtgggacgtgaccgccttggctgacggcattaagagcttccttctggca
ctgcccgcaccgctcgtgacccccgaggcctcggctgaggcgcgcagggccctgcgggag
gccgcggggcctgtggggccggcactggagccaccgacgctgccgctgcaccgcgcgctc
acgctgcgcttcctgctccagcacctgggccgcgtggcccgccgcgccccggccctgggt
cccgcggtccgggccctgggcgccacctttgggccgctgctgctgcgcgcgccgccgccg
tcctcgccgccgccagggggcgctcccgacgggagtgagcccagtcctgacttcccggca
ctgctggtggagaagctgcttcaggaacacttggaagagcaggaggttgcgcccccagcg
ctgccgcctaaaccccccaaggcaaagctggcccctgcaggcctggcgaatggagggagt
ccaccctccctgcaggatgccgagtggtactggggggacatttcaagggaggaggtgaac
gagaaactccgagacactcccgatggcaccttcctagtccgagatgcttccagcaagatc
cagggcgagtacacgctgaccctcaggaaaggcgggaacaataaactgatcaaggtcttc
caccgagatgggcactacggcttctcagagccactcaccttctgctccgtcgtggacctc
atcaatcactaccgccacgagtcgctggcccaatacaacgccaagctggacacacggctc
ctctaccctgtgtccaaataccagcaggaccagatcgtcaaggaggacagcgtggaggcg
gtgggcgcccagctcaaggtctatcaccagcagtaccaggacaagagccgcgagtatgac
cagctctatgaagagtacacacggacctcccaggagctgcagatgaagcgtaccgcgatt
gaggccttcaatgagactatcaagatctttgaagagcagggccagactcaagagaagtgc
agcaaggaatacctggagcgcttccggcgtgagggcaacgagaaagagatgcagaggatc
ctgcttaactctgagcggctcaagtcccgcattgccgagatccacgagagccgcacgaag
ctggagcagcagctgcgggcccaggcctcggacaaccgggagatcgacaagcgcatgaac
agcctcaagccagacctcatgcagctgcgtaagatccgagaccagtacctcgtgtggctc
acccagaaaggcgcccggcagaagaaaatcaacgagtggctggggatcaaaaatgagact
gaggaccagtacgcgctgatggaggacgaggacgatctcccgcaccacgaggaacgcact
tggtacgtgggcaagatcaaccgcacgcaggcagaggagatgctgagtggcaagcgggat
ggcaccttcctcatccgcgagagcagccagcggggctgctacgcctgctccgtggtggtg
gacggagacaccaagcactgcgtcatctaccgcacggccaccggcttcggcttcgcggag
ccctacaacctgtacgggtcgctgaaggagctggtgctgcactaccagcacgcctcgctc
gtgcagcacaacgacgcgctcaccgtcaccctggcgcacccagtacgcgccccgggcccc
ggcccgccgcctgccgcccgctga
DBGET
integrated database retrieval system