Macaca mulatta (rhesus monkey): 720040
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Entry
720040 CDS
T01028
Symbol
JAK3
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase JAK3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04062
Chemokine signaling pathway
mcc04151
PI3K-Akt signaling pathway
mcc04217
Necroptosis
mcc04550
Signaling pathways regulating pluripotency of stem cells
mcc04630
JAK-STAT signaling pathway
mcc04658
Th1 and Th2 cell differentiation
mcc04659
Th17 cell differentiation
mcc05161
Hepatitis B
mcc05162
Measles
mcc05166
Human T-cell leukemia virus 1 infection
mcc05169
Epstein-Barr virus infection
mcc05200
Pathways in cancer
mcc05203
Viral carcinogenesis
mcc05223
Non-small cell lung cancer
mcc05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
720040 (JAK3)
04151 PI3K-Akt signaling pathway
720040 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
720040 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
720040 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
720040 (JAK3)
04659 Th17 cell differentiation
720040 (JAK3)
04062 Chemokine signaling pathway
720040 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
720040 (JAK3)
05203 Viral carcinogenesis
720040 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
720040 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
720040 (JAK3)
05161 Hepatitis B
720040 (JAK3)
05162 Measles
720040 (JAK3)
05169 Epstein-Barr virus infection
720040 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
720040 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
720040 (JAK3)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
720040 (JAK3)
Protein kinases [BR:
mcc01001
]
Non-receptor tyrosine kinases
JAK family [OT]
720040 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
Kdo
Kinase-like
ABC1
FERM_C_FAK1
LRR_RI_capping
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
720040
NCBI-ProteinID:
XP_028694975
Ensembl:
ENSMMUG00000010996
LinkDB
All DBs
Position
19:complement(17345847..17368458)
Genome browser
AA seq
1169 aa
AA seq
DB search
MTVAQETKGPTQEGAEWDFPLAASRLCSPFEGPGSLPARQVALMAPPSEETPLXPQRSCS
LLSTEAGXLHVLLPARGPGPPXRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATED
LSYWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLDKCHRFGLRKDLASAILDLPVLEHL
FAQHRGDLVSGRLAVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPS
LRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVS
LPGVPGGQDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRL
VTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCH
GPSRKNLLDFAITSLRLGLTSWLYVLRRSPQDFDSFXLTVCVQTPLGPDYKGCLIRRSPT
GSFFLVGLSRSHSSLREXLAACWDGGLHVDGVTVTLTSCCIPRPKEKSNLIVVQRGRSPP
TSSLVQPQSNASXVRXYFHKIPADSLEWHMKPGHGSFTKIYRGLSPRGGGWESRKTEVLL
KVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDTYLRKR
GHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGTDGSPPFIKLSDPGVS
PAVLSLEMLTDRIPWVAPECLRKAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKL
QFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGA
LAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVK
QLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQ
RHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLP
LDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFL
RMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSTLGPQL
DMLWSGSRGCETHAFTAHPEGKPHSLSFL
NT seq
3510 nt
NT seq
+upstream
nt +downstream
nt
atgacagtggctcaggaaaccaaggggcccacacaggaaggagccgagtgggactttcct
ctcgctgcctcccggctctgctctcccttcgaaggtccagggtccctgcctgctaggcaa
gttgcactcatggcacctccaagtgaggagacacccctgnatcctcagcgctcctgcagc
ctcttgtccacggaggctggtngcctgcacgtgctactgcccgctcggggcccgggaccc
cccnagcgcctatctttctcctttggggaccacttggctgaggacctgtgcgtgcaggct
gccaaggccagcggcatcctgcctgtgtaccactccctctttgctttggccacggaggac
ctgtcctactggttccccccgagccacatcttctccgtggaggatgccagcacccaagtc
ctgctctacaggattcgtttttacttccccaattggtttgggctggacaagtgccaccgc
ttcgggctacgcaaggatttggccagcgctatccttgacctgccagtcctggagcacctc
tttgcccagcaccgcggtgacctggtgagtgggcgccttgctgtgggcctcagcctcaag
gagcagggtgagtgtctcagcctggccgtgctggacctggcccggatggcgcgagagcag
gcccagcggccaggagagctgctgaagactgtcagctacaaggcctgcctgcccccaagc
ctgcgcgacctgatccagggcctgagcttcgtgacgcggaggcgtattcggaggacagtg
cgcagggccctgcgccgcgtggccgcctgccaggccgaccggcactcgctcatggccaag
tacattatggatctggagcggctggatccggctggggccgccgagaccttccacgtgagc
ctccctggggtccctggtggccaggacgggctggggctgctccgcgtggctggtgacgga
ggaatcgcctggacccagggagaacaggaggtcctccagcccttctgcgactttccagaa
atcgtagacattagcatcaagcaggccccgcgcgttggcccggccggggagcaccgcctg
gtcactgtcaccaggacagacaaccagattttggaggccgagttcccggggctgcccgag
gctctgtctttcgtggcgctcgtggacggctacttccggctgaccacagactcccagcac
ttcttctgcaaggaggtggcaccgccgaggctgctggaggaggtggcagagcagtgccac
ggcccatcacgtaagaaccttctggactttgccataacaagcttaagactggggctcacg
tcctggctctatgttctccgccgcagcccccaggactttgacagcttcntcctcactgtc
tgtgtacagaccccccttggtcctgattataagggttgcctcattcggcgcagccccaca
gggagcttctttctggttggcctcagccgatcccacagcagtcttcgagagnctctggca
gcctgctgggatggggggctgcacgtagatggggtcacagtgaccctcacctcctgctgt
atccccagacccaaagaaaagtccaacttgatcgtggtccagagaggtcgcagcccaccc
acgtcctccctggttcagccccaatccaatgccagctgagtcagatgatatttccacaag
atccccgctgacagcctagagtggcacatgaaacctggccatggatccttcaccaagatt
taccgggggctgtcgccacgaggtggtggatgggagtcccgaaagacagaggtgctgcta
aaagtgatggatgctaagcacaagaactgcatggagtcattcctggaagcagcgagcttg
atgagccaagtgtcgtaccggcatctcgtgctgctccacggcgtgtgcatggctggagac
agcaccatggtgcaagaatttgtacacctgggggcgatagacacatatctgcgaaaacgt
ggccacctggtgccagccagctggaagctgcaggtggtcaaacagctggcctacgccctc
aactatctggaggacaaaggcctcccccatggcaatgtctccgcccggaaggtgctcctg
gctcgggagggcactgatgggagcccgcccttcatcaagctaagtgaccctggggtcagc
cccgctgtgttaagcctggagatgctcaccgacaggatcccctgggtggctcccgagtgt
cttcggaaggcccagacccttagcttggaagctgacaagtggggcttcggcgccacggtc
tgggaggtgtttagtggcgtcaccatgcccatcagcgccctggatcctgctaagaaactc
caattttatgaggaccggcagcagctgccagcccccaagtggacagagctggccctgcta
attcaacagtgcatggcctatgagccagtccagaggccctccttccgagccgtcattcgt
gacctcaacagcctcatctcttcagactatgagctcctctcagaccccacacctggtgcc
ctggcacctcgtgatgggctgtggaatggtgcccagctctatgcctgccaagaccccacg
atcttcgaggagagacacctcaagtacatctcacagctgggcaagggcaactttggcagc
gtggagctgtgccgctatgacccgctaggcgacaacacaggtgccctggtggccgtgaaa
cagctgcagcacagcgggccagaccagcagagggacttccagcgggagattcagatcctc
aaagcactgcacagtgatttcattgtcaagtatcgtggtgtcagctacggcccgggccgc
cagagcctgcggctggtcatggagtacctgcccagcggctgcttgcgcgacttcctgcag
cggcaccgcgcgcgcctggatgccagccgcctcctgctctactcctcgcagatctgcaag
ggcatggagtacctgggctcccgccgctgcgtgcaccgcgacctggccgcccgaaatatc
ctggtggagagcgaggcacacgtcaagatcgctgacttcggcctagctaagctgctgccg
cttgacaaagactactacgtggtccgcgagccgggccagagccccattttctggtatgcc
cccgaatccctctcggacaacatcttctctcgccagtcagacgtatggagcttcggggtc
gtcctgtacgagctcttcacctactgcgacaaaagctgcagcccctcggccgagtttctg
cggatgatgggatgtgagcgggatgtccccgccctctgccgcctcctggaactgctggag
gagggccagaggctgccggcgcctcctgcctgccctgctgaggttcacgagctcatgaag
ctgtgctgggcccctagcccacaggaccgcccatcattcagcaccctgggcccccagctg
gacatgctatggagcggaagccgggggtgtgagactcacgccttcactgctcacccagag
ggcaaaccacactccctgtcctttttatag
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