KEGG   Macaca fascicularis (crab-eating macaque): 101925657
Entry
101925657         CDS       T02918                                 
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X2
  KO
K04426  mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf01524  Platinum drug resistance
mcf04010  MAPK signaling pathway
mcf04071  Sphingolipid signaling pathway
mcf04141  Protein processing in endoplasmic reticulum
mcf04210  Apoptosis
mcf04530  Tight junction
mcf04668  TNF signaling pathway
mcf04714  Thermogenesis
mcf04722  Neurotrophin signaling pathway
mcf04932  Non-alcoholic fatty liver disease
mcf04936  Alcoholic liver disease
mcf05010  Alzheimer disease
mcf05012  Parkinson disease
mcf05014  Amyotrophic lateral sclerosis
mcf05016  Huntington disease
mcf05017  Spinocerebellar ataxia
mcf05022  Pathways of neurodegeneration - multiple diseases
mcf05208  Chemical carcinogenesis - reactive oxygen species
mcf05417  Lipid and atherosclerosis
mcf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    101925657 (MAP3K5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101925657 (MAP3K5)
   04668 TNF signaling pathway
    101925657 (MAP3K5)
   04071 Sphingolipid signaling pathway
    101925657 (MAP3K5)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    101925657 (MAP3K5)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    101925657 (MAP3K5)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101925657 (MAP3K5)
  09159 Environmental adaptation
   04714 Thermogenesis
    101925657 (MAP3K5)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    101925657 (MAP3K5)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101925657 (MAP3K5)
   05012 Parkinson disease
    101925657 (MAP3K5)
   05014 Amyotrophic lateral sclerosis
    101925657 (MAP3K5)
   05016 Huntington disease
    101925657 (MAP3K5)
   05017 Spinocerebellar ataxia
    101925657 (MAP3K5)
   05022 Pathways of neurodegeneration - multiple diseases
    101925657 (MAP3K5)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101925657 (MAP3K5)
   05418 Fluid shear stress and atherosclerosis
    101925657 (MAP3K5)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101925657 (MAP3K5)
   04932 Non-alcoholic fatty liver disease
    101925657 (MAP3K5)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101925657 (MAP3K5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    101925657 (MAP3K5)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     101925657 (MAP3K5)
Protein kinases [BR:mcf01001]
 Serine/threonine kinases: STE group
  STE11 family
   101925657 (MAP3K5)
SSDB
Motif
Pfam: MAP3K_TRAF_bd Pkinase HisK-N-like PK_Tyr_Ser-Thr ASK_PH TPR-S DRHyd-ASK FPP Kinase-like Pkinase_fungal
Other DBs
NCBI-GeneID: 101925657
NCBI-ProteinID: XP_005552001
Ensembl: ENSMFAG00000040944
LinkDB
Position
4:complement(join(40611253..40611313,40612294..40612370,40614983..40615095,40615954..40616066,40621092..40621335,40634509..40634614,40637680..40637865,40646314..40646482,40646579..40646756,40654765..40654785,40655558..40655735,40659244..40659401,40665368..40665473,40667220..40667356,40668256..40668383,40676976..40677109,40691733..40691814,40693922..40694017,40696834..40696883,40705577..40705684,40710897..40711050,40713807..40713966,40723856..40723968,40748805..40748975,40750613..40750719,40751879..40752047,40753155..40753348,40759849..40759872,40775303..40775442,40853748..40854426,40854673..40854768))
AA seq 1483 aa
MKGSCRQGGRRVLSAAAAAVPGRRPGSPPARKRASGAATEAPRRSEPPPGSGVPSGERAP
ERRRRRGGEGAARDGSCLARRARSSPELWLARRCGWAGDAAAVAARPGEMSTEAGEGITF
SVPPFAPSGFCTIPEGGICRRGGAAAVGESEEHQLPPPPPGSFWNVESAAAPGIGCPAAT
SASSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLH
FGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDS
LQSLKELICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICL
PLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTA
DIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKA
LDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQS
GINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDH
MRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATK
TDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRG
VSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCESDSL
EYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKH
LKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGL
KYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEII
DKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEA
KAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPVPV
LVEDTSSSSEYGSVSPDTELKADPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAP
PSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGSEEPKLKWEHITTLI
ASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHW
MFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQ
AVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLH
RAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSPGTNTEDSELTDWLRVNGADEDTISRFL
AEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQT
NT seq 4452 nt   +upstreamnt  +downstreamnt
atgaaggggagctgccgccaaggagggaggagggtgctttcggctgccgctgctgctgtt
ccgggacgtcgcccggggagcccgcccgctcgtaagagggcgagcggcgcggccacggag
gcgccgaggaggagcgagccgccgccgggcagcggcgtgccctcgggggagagggcgccg
gagaggaggcggcggcgaggcggcgagggcgcggcgcgcgatggcagctgcttagcccgg
cgggcgcggagcagccccgagctgtggctggccaggcggtgcggctgggcgggggacgcc
gccgccgttgctgcccggcccggagagatgagcacggaggcgggcgagggcatcactttc
tccgtgccacccttcgccccctcgggcttctgcaccatccccgagggcggcatctgcagg
aggggaggagcggcggcggtgggcgagagcgaggagcaccagctgccaccgccgccgccg
ggcagcttctggaacgtggagagcgccgccgccccaggcatcgggtgtcccgcggccacc
tccgcgagcagtgccacccgaggccggggcagctctgttggcgggggcagccgacggacc
acggtggcatatgtgatcaacgaagcgagccaggggcaactggtggtggccgagagcgag
gccctgcagagcttgcgggaggcgtgcgagacggtgggcgccaccctggaaaccctgcat
tttgggaaactcgactttggtgaaaccaccgtcctggaccgcttttacaatgcagatatt
gcggtggtggagatgagcgatgccttccggcaaccgtccttgttttaccaccttggggtg
agagaaagtttcagcatggccaacaacatcatcctctactgtgatactaactcggactct
ctgcagtcgctgaaggaactcatttgccagaagaatactatgtgcactgggaactacacc
tttgttccttatatgataacgccacataacaaggtctactgctgtgacagcagcttcatg
aaggggttgacagagctcatgcaaccgaacttcgagctgcttcttggacccatctgctta
cctcttgtggatcgttttattcaacttttgaaggtggcacaagcaagttctagccagtat
ttccgggaatctatactcaatgatatcaggaaagctcgtaatttatacactggtaaagaa
ttggcagctgagttggcaagaattcggcagcgagtagataatatcgaagtcttgacagca
gatattgtcataaatctgttactttcctacagagatatccaggactatgattctattgtg
aagctggtagagactttagaaaaactgccaacctttgatttggcctcccatcaccatgtg
aagtttcattatgcatttgcactgaataggagaaatctccctggagacagagcaaaagct
cttgatattatgattcccatggtgcaaagtgaaggacaagttgcttcagatatgtattgc
ctagttggtcgaatctacaaagatatgtttttggactctaatttcacagacacggaaagt
agagaccatggagcttcttggttcaaaaaggcatttgaatctgagccaacactacagtca
ggaattaattatgcggtcctcctcctggcagctgggcaccagtttgaatcttcctttgag
ctccggaaagttggggtgaagctaagtagtcttcttggtaaaaagggaaacttggagaaa
ctccagagctactgggaagttggattttttctgggggccagtgtcctagccaatgaccac
atgagagtcattcaagcatctgaaaagctttttaaactgaagacaccagcgtggtacctc
aagtctattgtagagacaattttgatatataagcattttgtgaaactgaccacagaacag
cctgtggccaagcaagaacttgtggacttttggatggatttcctggtcgaggccacaaag
accgatgttactgtggttaggtttccagtattaatattagaaccaaccaaaatctatcaa
ccttcttatttgtctatcaacaatgaagttgaggaaaagacaatctctatttggcacgtg
cttcctgatgacaagaaaggtatacatgagtggaattttagtgcctcttctgtcagggga
gtgagtatttctaaatttgaagaaagatgctgctttctttatgtgctccacaattctgat
gatttccaaatctatttctgtacagaacttcattgtaaaaagttttttgagatggtgaac
accattaccgaagagaaggggagaagcacagaggaaggagactgtgaaagtgactcgctg
gagtatgactatgaatatgatgaaaatggtgacagagtcgttttaggaaaaggcacttac
gggatagtctacgcaggtcgggacttgagcaaccaagtcagaattgctattaaggaaatc
ccagagagagacagcagatactctcagcccctgcatgaagaaatagcattgcataagcac
ctgaagcacaaaaatattgtccagtatctgggctctttcagtgagaatggtttcattaaa
atcttcatggagcaggtccctggaggaagtctttctgctctccttcgttccaaatggggt
ccattaaaagataatgagcaaacaattggcttttatacaaagcaaatactggaaggatta
aaatatctccatgacaatcagatagttcaccgcgacataaagggtgacaatgtgttgatt
aatacctacagtggtgttctcaagatctctgacttcgggacatcaaagaggcttgctggc
ataaacccctgtactgaaacttttactggtaccctccagtatatggcaccagaaataata
gataaaggaccaagaggctatggaaaagcagcagacatctggtctctgggctgtacaatc
atcgaaatggccacaggaaaacccccattttatgaactgggagaaccacaagcagctatg
ttcaaggtgggaatgtttaaagtccaccctgagatcccagaatccatgtctgcagaggcc
aaggcattcatcctgaaatgttttgaaccagaccctgacaagagagcctgtgctaacgac
ttgcttgttgatgagtttttaaaagtttcaagcaaaaagaaaaagacacaacctaagctt
tcagctctttcagctggatcaaatgaatatctcaggagtatatctttgccagtacctgtg
ctggtggaggacaccagcagcagcagtgagtacggctcagtttcacccgacacggagttg
aaagcggaccccttctctttcaaaacaagagccaaatcctgcggagaaagagatgtcaag
ggaattcggacactctttttgggcattccagatgagaattttgaagatcacagtgctccc
ccttcccctgaagaaaaagattccggattcttcatgctgaggaaggacagtgagaggcga
gccacccttcacaggatcctgacagaagaccaagacaaagttgtgagaaatctaatggaa
tctttagctcaggggtctgaagaacccaaactaaaatgggaacacatcacaaccctcatt
gcaagcctcagagaatttgtgagatccactgaccgaaaaatcatagccaccacattgtca
aagctgaaactggagctggacttcgacagccatggcattagccaagtccaggtggtgctc
tttggttttcaagatgctgtcaataaagttcttcggaatcataacatcaagccgcactgg
atgtttgccttagacagtatcatccggaaggcggtgcagacagccattaccatcctggtt
ccagaactaaggccacatttcagccttgcatctgagagtgatactgctgatcaagaagac
ttggatgtagaagatgaccatgaggaacagccttcaaatcaaactgtccgaagacctcag
gctgtcattgaagatgccgtggctacctcaggcgtgagcacgcttagttctactgtgtct
catgattcccagagtgctcaccggtcactgaatgtacagcttggaaggatgaaaatagaa
accaatagattactggaagaattggttcggaaagagaaggaattacaagcactccttcat
cgagctattgaagaaaaagaccaagaaattaaacacctgaagcttaagtcccaacccata
gaaattcctgaactgcctgtatttcacctaaattctcctggcacaaatactgaagattct
gagcttaccgactggctgagagtgaatggagcggatgaagacactataagccggtttttg
gctgaagattatacactattggatgttctctactatgttacacgtgatgacttaaaatgc
ttgagactaaggggagggatgctgtgcacactgtggaaggccatcattgactttcgaaac
aaacagacttga

DBGET integrated database retrieval system