KEGG   Macaca fascicularis (crab-eating macaque): 101925733
Entry
101925733         CDS       T02918                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf01522  Endocrine resistance
mcf04110  Cell cycle
mcf04115  p53 signaling pathway
mcf04151  PI3K-Akt signaling pathway
mcf04218  Cellular senescence
mcf04530  Tight junction
mcf04660  T cell receptor signaling pathway
mcf04933  AGE-RAGE signaling pathway in diabetic complications
mcf04934  Cushing syndrome
mcf05160  Hepatitis C
mcf05162  Measles
mcf05163  Human cytomegalovirus infection
mcf05164  Influenza A
mcf05165  Human papillomavirus infection
mcf05166  Human T-cell leukemia virus 1 infection
mcf05167  Kaposi sarcoma-associated herpesvirus infection
mcf05169  Epstein-Barr virus infection
mcf05200  Pathways in cancer
mcf05203  Viral carcinogenesis
mcf05212  Pancreatic cancer
mcf05214  Glioma
mcf05218  Melanoma
mcf05219  Bladder cancer
mcf05220  Chronic myeloid leukemia
mcf05222  Small cell lung cancer
mcf05223  Non-small cell lung cancer
mcf05224  Breast cancer
mcf05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    101925733 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    101925733 (CDK4)
   04115 p53 signaling pathway
    101925733 (CDK4)
   04218 Cellular senescence
    101925733 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    101925733 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    101925733 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101925733 (CDK4)
   05203 Viral carcinogenesis
    101925733 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    101925733 (CDK4)
   05225 Hepatocellular carcinoma
    101925733 (CDK4)
   05214 Glioma
    101925733 (CDK4)
   05220 Chronic myeloid leukemia
    101925733 (CDK4)
   05218 Melanoma
    101925733 (CDK4)
   05219 Bladder cancer
    101925733 (CDK4)
   05224 Breast cancer
    101925733 (CDK4)
   05222 Small cell lung cancer
    101925733 (CDK4)
   05223 Non-small cell lung cancer
    101925733 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101925733 (CDK4)
   05160 Hepatitis C
    101925733 (CDK4)
   05164 Influenza A
    101925733 (CDK4)
   05162 Measles
    101925733 (CDK4)
   05163 Human cytomegalovirus infection
    101925733 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101925733 (CDK4)
   05169 Epstein-Barr virus infection
    101925733 (CDK4)
   05165 Human papillomavirus infection
    101925733 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101925733 (CDK4)
   04934 Cushing syndrome
    101925733 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101925733 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    101925733 (CDK4)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     101925733 (CDK4)
Protein kinases [BR:mcf01001]
 Serine/threonine kinases: CMGC group
  CDK family
   101925733 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 101925733
NCBI-ProteinID: XP_045221451
Ensembl: ENSMFAG00000043769
UniProt: I7GNS2
LinkDB
Position
11:complement(join(64567401..64567493,64568057..64568192,64568329..64568379,64569543..64569652,64569810..64569977,64570095..64570230,64570386..64570603))
AA seq 303 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacctctcgatatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggagctggaggaggccttcccatcagcacagttcgggaggtggccttactg
aggcgactggaggcttttgaacatcccaatgtagtccggctgatggacgtctgtgccaca
tcccgaactgaccgggagatcaaggtaaccctggtgtttgagcatgtagaccaagaccta
aggacgtatctggacaaagcacccccaccaggcttgccagccgagaccatcaaggatttg
atgcgccagtttctaagaggcctagatttccttcatgcaaattgcatcgttcaccgagat
ctgaagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacccgtggttgttacactctggtac
cgagctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct
gaccagttgggcaaaatctttgacctgattgggctgcctccagaggatgactggcctcga
gatgtatccctgccccgtggagcctttccccccagagggccccgcccagtgcagtcggtg
gtacctgagatggaggagtcgggagcacagctgctgctggaaatgctgacttttaaccca
cacaagcgaatctctgcctttcgagctctgcagcactcttatctacataaggatgaaggt
aatccggagtga

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