Macaca fascicularis (crab-eating macaque): 102116844
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Entry
102116844 CDS
T02918
Name
(RefSeq) aldo-keto reductase family 1 member C4-like isoform X1
KO
K00037
3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:
1.1.1.50
1.1.1.357
1.1.1.225
]
Organism
mcf
Macaca fascicularis (crab-eating macaque)
Pathway
mcf00120
Primary bile acid biosynthesis
mcf00140
Steroid hormone biosynthesis
mcf01100
Metabolic pathways
mcf05208
Chemical carcinogenesis - reactive oxygen species
Module
mcf_M00104
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
mcf_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
mcf00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
102116844
00140 Steroid hormone biosynthesis
102116844
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
102116844
Enzymes [BR:
mcf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
102116844
1.1.1.225 chlordecone reductase
102116844
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
102116844
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Gene cluster
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Motif
Pfam:
Aldo_ket_red
GT-D-like
Motif
Other DBs
NCBI-GeneID:
102116844
NCBI-ProteinID:
XP_045255423
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All DBs
Position
9:join(6164954..6165037,6174700..6174777,6175210..6175332,6181154..6181263,6181529..6181694,6185189..6185271,6187147..6187189)
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AA seq
228 aa
AA seq
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MDPKYQRVELNDGHFMPVLGFGTYVPPEPGETPLPKDENGKVMFDTVDLCAIWEAMEKCK
DAGLAKSIRVSNFNRRQLEMILNNPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVA
HSALGTQRHKLWVDQNSPALLEDPVLCALAKKHKPSPALIALRYQLQRGVVVLAKSYNEQ
RIRENVQVFEFQLTSEDMKVLDGLNGNFRYAVMDFLVDHPDYPFSDEY
NT seq
687 nt
NT seq
+upstream
nt +downstream
nt
atggatcccaaatatcagcgtgtggagctaaatgatggtcatttcatgcctgtattagga
tttggcacctatgtgcctccagagccaggtgagacgccactaccaaaagatgaaaatgga
aaagtaatgttcgacacagtggatctctgtgccatatgggaggccatggagaagtgtaag
gatgcaggattggccaagtccatcagggtgtcaaacttcaaccgcagacagctggagatg
atcctcaacaacccaggactcaagtacaagcccgtctgcaaccaggtggaatgtcatcct
tacctcaaccagagcaaactgctggatttctgcaagtcaaaagacattgtcctggttgcc
catagtgctctgggaacccaacgacataaactatgggtggaccagaactccccagctctt
ttggaagacccagttctttgtgccttagcaaagaagcacaaaccatccccagccctgatt
gccttgcgctaccagctgcagcgtggggttgtggtcctggccaagagctacaatgaacag
cggatcagagaaaacgtccaggtttttgaattccagttgacttcggaggatatgaaagtt
ctagatggcctaaacggaaattttcgatatgctgtcatggattttcttgtggaccaccct
gattatccattttcagatgaatattag
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