| Entry |
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| Name |
(RefSeq) aldo-keto reductase family 1 member C4 isoform X1
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| KO |
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| Organism |
mcf Macaca fascicularis (crab-eating macaque)
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| Pathway |
| mcf05208 | Chemical carcinogenesis - reactive oxygen species |
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| Module |
| mcf_M00104 | Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate |
| mcf_M00977 | C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone |
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| Brite |
KEGG Orthology (KO) [BR:mcf00001]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
102117205
00140 Steroid hormone biosynthesis
102117205
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
102117205
Enzymes [BR:mcf01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
102117205
1.1.1.225 chlordecone reductase
102117205
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
102117205
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
9:complement(join(6087270..6087312,6089211..6089293,6092849..6093014,6093280..6093389,6105862..6105984,6106416..6106493,6107782..6107898,6115890..6116057,6119166..6119249))
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| AA seq |
323 aa
MDPKYQRVALNDGHFMPVLGFGSYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPM
ALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNP
GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPV
LCALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMKVLDDLN
RNFRYVVMDFLVDHPDYPFSDEY |
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| NT seq |
972 nt +upstreamnt +downstreamnt
atggatcccaaatatcagcgtgtggcgctaaatgatggtcacttcatgcccgtattggga
tttggctcctatgcacctccagaggttccgaggaacagagttgtggaggtcaccaaattg
gcaatagaagctggcttccgccatattgattctgcttatttatacaacaatgaggagcaa
gttggactggccatccgaagcaagattgcagacggcagtgtgaagagagaagacatattc
tacacttcaaagctttggtgcactttctttcgaccacagttggtccaaccagccttggaa
agctcactgaaaaaacttcaactggactatgtggacctctatcttattcatttcccaatg
gctctcaagccaggtgagacgccactaccaaaagatgaaaatggaaaagtaatgttcgac
acagtggatctctgtgccatatgggaggccatggagaagtgtaaggatgcaggattggcc
aagtccatcggggtatcaaacttcaaccgcagacagctggagatgatcctcaacaacccg
ggactcaagtacaagcccgtctgcaaccaggtggaatgtcatccttacctcaaccagagc
aaactgctggatttctgcaagtcaaaagacattgtcctggttgcccatagtgctctggga
acccaacgacataaactatgggtggaccagaactccccagctcttttggaggacccagtt
ctttgcgccttagcaaagaaacacaaacgatccccagccctgattgccctgcgctaccag
ctgcagcgtggggttgtggtcctggccaagagctacaatgagcagcggatcagagaaaat
gtccaggtttttgaattccagttgacttcagaggatatgaaagttctagatgacctaaac
agaaattttcgatatgttgtcatggattttcttgtggaccaccctgattatccattttca
gatgaatattag |
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