KEGG   Macaca fascicularis (crab-eating macaque): 102121518
Entry
102121518         CDS       T02918                                 
Symbol
HK2
Name
(RefSeq) hexokinase-2 isoform X1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf00010  Glycolysis / Gluconeogenesis
mcf00051  Fructose and mannose metabolism
mcf00052  Galactose metabolism
mcf00500  Starch and sucrose metabolism
mcf00520  Amino sugar and nucleotide sugar metabolism
mcf00524  Neomycin, kanamycin and gentamicin biosynthesis
mcf01100  Metabolic pathways
mcf01200  Carbon metabolism
mcf01250  Biosynthesis of nucleotide sugars
mcf04066  HIF-1 signaling pathway
mcf04910  Insulin signaling pathway
mcf04930  Type II diabetes mellitus
mcf04973  Carbohydrate digestion and absorption
mcf05230  Central carbon metabolism in cancer
Module
mcf_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mcf_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    102121518 (HK2)
   00051 Fructose and mannose metabolism
    102121518 (HK2)
   00052 Galactose metabolism
    102121518 (HK2)
   00500 Starch and sucrose metabolism
    102121518 (HK2)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    102121518 (HK2)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    102121518 (HK2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    102121518 (HK2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102121518 (HK2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    102121518 (HK2)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    102121518 (HK2)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102121518 (HK2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mcf04131]
    102121518 (HK2)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     102121518 (HK2)
Membrane trafficking [BR:mcf04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    102121518 (HK2)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1 FGGY_N
Other DBs
NCBI-GeneID: 102121518
NCBI-ProteinID: XP_045224941
Ensembl: ENSMFAG00000035505
UniProt: A0A2K5V9E3
LinkDB
Position
13:complement(join(47045938..47046082,47047397..47047630,47048822..47048977,47050176..47050359,47050456..47050555,47051232..47051327,47054553..47054672,47054933..47055081,47056211..47056515,47057861..47058094,47059426..47059581,47062056..47062239,47062559..47062658,47063150..47063245,47064100..47064219,47068636..47068784,47080618..47080780,47099679..47099741))
AA seq 917 aa
MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAA
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMR
GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV
EGRDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME
EMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLG
LDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTVGVDGSVYKKH
PHFAKCLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEPLQLS
HDQLLEVKRRMKVEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG
TMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD
FCTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDKIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLQSEDGSGKG
AALITAVACRIREAGQR
NT seq 2754 nt   +upstreamnt  +downstreamnt
atgattgcctcgcatctgctcgcctacttcttcacggagctcaaccatgaccaagtgcag
aaggttgaccagtatctctaccacatgcgcctctctgatgagaccctcttggagatctct
aagcggttccgcaaggagatggagaaagggcttggagccaccacccaccccactgcagca
gtgaagatgctgcccacctttgtgaggtccactccagatgggacagaacacggagagttc
ctggctctggaccttggagggaccaacttccgtgtgctttgggtgaaagtaacggacaat
gggcttcagaaggtggagatggagaaccagatctatgccatccccgaggacatcatgcga
ggcagtggcacccagctgtttgaccacattgccgaatgcctggctaacttcatggataag
ctacaaatcaaagacaagaagctcccattgggtttcaccttctcgtttccctgccaccag
actaaactagacgagagtttcctggtctcatggaccaagggattcaagtccagtggagtg
gaaggcagagacgttgtgactttgatccggaaggccatccagcggagaggggactttgat
atcgacattgtggctgtggtgaatgacacagttgggaccatgatgacctgtggttatgat
gaccacaactgtgagattggtctcattgtgggcacgggcagcaacgcctgctacatggaa
gagatgcgccacatcgacatggtggaaggtgacgaggggcggatgtgtatcaatatggag
tggggggccttcggggacgatggctcgctcaacgacattcgcactgagtttgaccaggag
attgacatgggctcgctgaacccagggaagcaactgtttgagaagatgatcagtgggatg
tacatgggggagctggtgaggcttatcctggtgaagatggccaaggaggagctgctcttt
ggggggaagctcagcccagagctcctcaacaccggtcgctttgagaccaaagacatctca
gatatcgaaggggagaaggatggcatccggaaggcccgtgaggtcctgatgcggttgggc
ctggacccgactcaggaggactgcgtggccactcaccgaatctgccagattgtgtccaca
cgctccgccagcctgtgcgcagccaccctggccgccgtgctgcagcgcatcaaggagaac
aaaggcgaggagcggctgcgctctactgttggggttgacggctccgtctacaagaaacac
ccccatttcgctaagtgtctacataagaccgtgcggcggctggtgcccgactgcgatgtc
cgcttcctccgctccgaggatggcagtggcaaaggtgcagccatggtgacagcagtggct
taccggctggccgatcaacaccgagcccgccagaagacactggagcctctgcagctgagc
catgaccagctgttggaggtcaagagaagaatgaaggtggaaatggagcgaggtctaagc
aaggagactcatgccattgcccccgtcaagatgctgcccacctacgtgtgtgccacccct
gatggcacagagaaaggggacttcttggccttggaccttggaggaacaaatttccgggtc
ctgctggtgcgtgttcggaatgggaagtggggtggagtggagatgcacaacaagatctac
gccatcccgcaggaggtcatgcatggtaccggggacgagctctttgaccacattgtccag
tgcatcgcggacttccttgagtacatgggcatgaagggcgtgtccctgcctctgggtttt
accttctccttcccctgccagcagaacagcctggacgagagcatcctcctcaagtggaca
aaaggcttcaaggcatctggctgtgagggcgaggacgtggtgaccctgctgaaggaagcg
atccaccggcgagaggagtttgacctggatgtggttgccgtggtgaacgacacagttgga
actatgatgacctgtggctttgaagaccctcactgtgaagttggcctcatcgttggcacg
ggcagcaatgcctgctacatggaggagatgcgcaatgtggaactggtggaaggagaagag
gggcggatgtgtgtgaacatggaatggggggccttcggggacaatggatgcctagatgac
ttctgcacggaatttgatgtggctgtggatgagctttcactcaaccccggcaagcagagg
ttcgagaaaatgatcagtggaatgtacctaggtgagattgtccgtaacattctcatcgat
ttcaccaagcgtgggctgctcttccgaggtcgcatctcagagcggctcaagacaaggggc
atcttcgaaaccaagttcttgtctcagattgagagtgactgcctggccctgctgcaagtc
cgtgccatcctgcaacacttagggcttgagagcacctgtgatgacagcatcattgttaag
gaggtgtgcactgtggtggccagacgcgcagcccagctctgtggcgcaggcatggccgct
gtggtggacaagatacgagaaaaccgtgggctggacgctctcaaagtgacagtgggtgtg
gatgggactctctacaagctacatcctcactttgccaaagtcatgcatgagacagtgaag
gacctggctccaaaatgtgatgtgtctttcctgcagtcagaggatggcagcggaaagggg
gctgcgctcatcactgctgtggcctgccgcatccgtgaggctggacagcgatag

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