KEGG   Macaca fascicularis (crab-eating macaque): 102128947
Entry
102128947         CDS       T02918                                 
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf01521  EGFR tyrosine kinase inhibitor resistance
mcf04010  MAPK signaling pathway
mcf04014  Ras signaling pathway
mcf04015  Rap1 signaling pathway
mcf04020  Calcium signaling pathway
mcf04144  Endocytosis
mcf04151  PI3K-Akt signaling pathway
mcf04550  Signaling pathways regulating pluripotency of stem cells
mcf04810  Regulation of actin cytoskeleton
mcf05200  Pathways in cancer
mcf05206  MicroRNAs in cancer
mcf05219  Bladder cancer
mcf05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102128947 (FGFR3)
   04014 Ras signaling pathway
    102128947 (FGFR3)
   04015 Rap1 signaling pathway
    102128947 (FGFR3)
   04020 Calcium signaling pathway
    102128947 (FGFR3)
   04151 PI3K-Akt signaling pathway
    102128947 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102128947 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102128947 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102128947 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102128947 (FGFR3)
   05206 MicroRNAs in cancer
    102128947 (FGFR3)
   05230 Central carbon metabolism in cancer
    102128947 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    102128947 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102128947 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    102128947 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mcf04090]
    102128947 (FGFR3)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102128947 (FGFR3)
Protein kinases [BR:mcf01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   102128947 (FGFR3)
CD molecules [BR:mcf04090]
 Proteins
  102128947 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 FGFR3_TM V-set C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 102128947
NCBI-ProteinID: XP_045247957
Ensembl: ENSMFAG00000032292
LinkDB
Position
5:join(1937467..1937575,1942843..1943112,1943335..1943400,1944950..1945122,1945197..1945320,1945410..1945600,1946494..1946644,1947901..1948091,1948391..1948539,1948917..1949038,1949117..1949227,1949311..1949501,1949612..1949734,1949817..1949887,1950105..1950242,1950386..1950491,1950664..1950810)
AA seq 810 aa
MGAPACALALCVAVAIVAGASSESLGTEQRVVGRVAEVSGPEPSQQEQLVFGSGDAVELS
CPPPGGGPMGPTVWVKDGAGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQLVLCH
FSVRVTDAPSSGDDEDGEDEAEDTGVDTAGAPYWTRPERMDKKLLAVPAANTVRFRCPAA
GNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQ
TYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVG
PDGTPYVTVLKSWISESVEADVRLRLANVSERDGGEYLCRATNFIGVAEKAFWLSVHGPR
AAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSTPKKGLGSPTVHKISRF
PLKRQQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGK
PLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHK
NIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVS
CAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRL
PVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKP
ANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQD
TPSSSSSGDDSVFAHDLLPPAPPSSGGSRT
NT seq 2433 nt   +upstreamnt  +downstreamnt
atgggcgcccctgcctgcgccctcgcgctctgcgtggcagtggccatcgtggccggcgcc
tcctcggagtccttggggacggagcagcgcgtcgtggggcgagtggcagaagtgtccggc
ccggagcccagccagcaggagcagttggtcttcggcagcggggacgctgtggagctgagc
tgtcccccgcccgggggtggtcccatggggcccactgtctgggtcaaggatggcgcaggg
ctggtgccctcggagcgtgtcctggtggggccccagcggctgcaggtgctgaatgcctcc
cacgaggactctggggcctacagctgccggcagcggctcacacagctcgtactgtgccac
ttcagtgtgcgggtgacagatgctccatcctcgggagatgacgaagacggggaggacgag
gctgaggacacaggtgtggacacagcaggggccccttactggactcggcccgagcggatg
gacaagaagctgctggctgtgccggccgccaacaccgtccgcttccgctgcccggctgcc
ggcaaccccactccctccatctcctggctgaagaatggcaaggagttccgcggcgagcac
cgcattggaggcatcaagcttcggcaccagcagtggagcctggtcatggaaagtgtggtg
ccctcggaccgcggcaactacacctgcgtggtggagaacaagttcggcagcatccggcag
acatacacgctggacgtgctggagcgctccccgcaccggcccatcctgcaggcggggctg
ccggccaaccagacggcggtgctgggcagcgatgtggagtttcactgcaaggtgtacagt
gatgcgcagccccacatccagtggctcaagcacgtggaggtgaatggcagcaaggtgggc
cccgacggcacaccctacgtcaccgtgctcaagtcctggatcagtgagagtgtggaggcc
gacgtgcgcctccgcctggccaatgtgtcggagcgggacgggggcgagtacctctgtcga
gccaccaatttcataggcgtggccgagaaggccttttggctgagcgttcacgggccccga
gcagctgaggaggagctggtggaggctgacgaggcgggcagtgtgtacgcaggcatcctc
agctacggggtgggcttcttcctgttcatcctggtggtggcggctgtgacgctctgccgc
ctgcgcagcacccccaagaaaggcctgggctcccccaccgtgcacaagatctcccgcttc
ccactcaagcgacagcaggtgtccctggagtccaacgcgtccatgagctccaacacaccg
ctggtgcgcatcgcaaggctgtcctcaggggagggtcccacgctggccaatgtctccgag
cttgagctgcctgctgaccccaaatgggagctgtctcgggcccggctgaccctgggcaag
ccccttggggagggctgcttcggccaggtggtcatggcggaggctatcggcattgacaag
gaccgggccgccaagcctgtcaccgtagccgtgaagatgctgaaagatgatgccactgac
aaggacctgtcagacctggtgtctgagatggagatgatgaagatgattgggaaacacaag
aacattatcaacctgctgggcgcctgcacgcagggcgggcccctgtacgtgctggtggag
tacgcggccaagggcaacctgagggagtttctgcgggcgcggcggcccccgggcctggac
tactccttcgacacctgcaagccgcctgaggagcagctcaccttcaaggacctggtgtcc
tgtgcctaccaggtggcccgaggcatggagtacctcgcctcccagaagtgcatccacagg
gacctggctgctcgaaatgtgctggtgaccgaggacaacgtgatgaagatcgcagacttc
gggctggcccgcgacgtgcacaaccttgactactacaagaagacaaccaacggccggctg
cccgtgaagtggatggcgcctgaggccctgtttgaccgagtctacacccaccagagtgac
gtctggtcctttggggtcctgctctgggagatcttcacgctggggggctctccgtacccc
ggcatccctgtggaggagctcttcaagctgctgaaggagggtcaccggatggacaagccg
gccaactgcacacacgacctgtacatgatcatgcgggagtgctggcatgctgcgccctcc
cagaggcccaccttcaagcagctggtggaggacctggaccgtgtcctcactgtgacgtcc
accgacgagtacctggacctgtcagcgcccttcgagcagtactcccccggcggccaggac
accccgagctccagctcctcaggggatgactccgtgtttgcccacgacctgctgcccccg
gccccacccagcagtgggggctcgcggacgtga

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