Macaca fascicularis (crab-eating macaque): 107126974
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Entry
107126974 CDS
T02918
Symbol
UGT1A8
Name
(RefSeq) UDP glucuronosyltransferase 1 family, polypeptide A8 precursor
KO
K00699
glucuronosyltransferase [EC:
2.4.1.17
]
Organism
mcf
Macaca fascicularis (crab-eating macaque)
Pathway
mcf00040
Pentose and glucuronate interconversions
mcf00053
Ascorbate and aldarate metabolism
mcf00140
Steroid hormone biosynthesis
mcf00830
Retinol metabolism
mcf00860
Porphyrin metabolism
mcf00980
Metabolism of xenobiotics by cytochrome P450
mcf00982
Drug metabolism - cytochrome P450
mcf00983
Drug metabolism - other enzymes
mcf01100
Metabolic pathways
mcf01240
Biosynthesis of cofactors
mcf04976
Bile secretion
mcf05204
Chemical carcinogenesis - DNA adducts
mcf05207
Chemical carcinogenesis - receptor activation
Module
mcf_M00014
Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:
mcf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00040 Pentose and glucuronate interconversions
107126974 (UGT1A8)
00053 Ascorbate and aldarate metabolism
107126974 (UGT1A8)
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
107126974 (UGT1A8)
09108 Metabolism of cofactors and vitamins
00830 Retinol metabolism
107126974 (UGT1A8)
00860 Porphyrin metabolism
107126974 (UGT1A8)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
107126974 (UGT1A8)
00982 Drug metabolism - cytochrome P450
107126974 (UGT1A8)
00983 Drug metabolism - other enzymes
107126974 (UGT1A8)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
107126974 (UGT1A8)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
107126974 (UGT1A8)
05207 Chemical carcinogenesis - receptor activation
107126974 (UGT1A8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
mcf01003
]
107126974 (UGT1A8)
Enzymes [BR:
mcf01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.17 glucuronosyltransferase
107126974 (UGT1A8)
Glycosyltransferases [BR:
mcf01003
]
Others
Hydrophobic molecule
107126974 (UGT1A8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
UDPGT
EryCIII-like_C
Glyco_tran_28_C
Docking
Motif
Other DBs
NCBI-GeneID:
107126974
NCBI-ProteinID:
NP_001336952
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All DBs
Position
12:join(129554481..129555335,129703648..129703779,129704449..129704536,129704791..129705010,129709176..129709473)
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AA seq
530 aa
AA seq
DB search
MARTRWTSPVLLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMP
EVSWQLGRSLNCTVKTYSTSYTLEDLDREFMTFAHAQWKAQLRSFFSLFLSSSNGFFDLF
FSHCRSLFNDQKLVEYLKESSFDAVFLDPFDGCGLILAKYFSLPSVVFARGIFCHYLEEG
AQCPAPLSYVPRILLGFSDAMTFKERVWNHVMHLEEHLFCKYFFKNALEIASEILQTPVT
AYDLYSHTSIWLLRTDFVLDYPKPVMPNMVFIGGINCHQGKPVPMEFEAYINASGEHGIV
VFSLGSMVAEIPEKKAMAIADALGKIPQTVLWRYTGTPPSNLANNTILVKWLPQNDLLGH
PMTRAFITHAGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL
ENALKAVINDKSYKENIMHLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW
YQYHSLDVIGFLLAIVLTVAFIAFKCCAYGYRKCFGKKGRVKKAHKSKTH
NT seq
1593 nt
NT seq
+upstream
nt +downstream
nt
atggctcgcacacggtggaccagccctgttttcctatgtgtttctctgctgctgacctgt
ggatttgctgaggcagggaagctgctggtagtgcccatggatgggagccattggttcacc
atgcagtcggtggtggagaagcttatcctcagggggcatgaggtggtggtagtcatgcca
gaggtgagttggcaactgggaagatcactgaattgcacagtgaagacttattcaacctca
tacactctggaggatctggaccgggaattcatgactttcgcccatgctcaatggaaagca
caattacgaagtttcttttctctatttctgagttcatccaatggtttttttgatttattt
ttttcgcattgcaggagtttgtttaatgaccaaaaattggtagaatatttaaaggagagt
tcttttgatgcggtgtttctggatccttttgatggctgtggcttaattcttgccaaatat
ttctccctcccctctgtggtctttgccaggggaatattttgccactatcttgaagaaggt
gcacagtgccctgctcctctttcctatgtccccagaattctcttagggttctcagatgcc
atgactttcaaggagagagtatggaaccatgtcatgcacttggaggaacatttattttgc
aagtattttttcaaaaatgccctagaaatagcctctgaaattctccaaacacctgtcacg
gcatatgatctctacagccacacatcaatttggttgttgcgaacggactttgttttggac
tatcccaaacccgtgatgcccaacatggtcttcattggtggtatcaactgccatcaggga
aagccagtgcctatggaatttgaagcctacattaatgcttctggagaacatggaattgtg
gttttctctttgggatcaatggtcgcagaaattccagagaagaaagctatggcaattgct
gatgctttgggcaaaatccctcagacagtcctgtggcggtacactggaaccccaccatcg
aatcttgcgaacaatacgatacttgttaagtggctaccccaaaacgatcttcttggtcac
ccaatgacccgtgcctttatcacccatgctggttcccatggtatttatgaaggcatatgc
aatggcgttcccatggtgatgatgcccttgtttggtgatcagatggacaatgcaaagcgc
atggagactaagggagctggagtgaccctgaatgttcttgaaatgacttctgaagattta
gaaaatgccctaaaagcagtcatcaatgacaaaagctacaaggagaacatcatgcacctc
tccagccttcacaaggaccgcccggtggagccgctggacctggctgtgttctgggtggag
tttgtgatgaggcacaagggcgcaccacacctgcgccccgcagcccacgacctcacctgg
taccagtaccattccttggacgtgatcggtttcctcctggccatcgtgctgacagtggcc
ttcatcgcctttaaatgttgtgcctatggctaccggaaatgcttcgggaaaaaagggcga
gttaagaaagcccacaaatccaagacccattga
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