Mastomys coucha (southern multimammate mouse): 116069491
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Entry
116069491 CDS
T07224
Symbol
Pik3r2
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit beta
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01521
EGFR tyrosine kinase inhibitor resistance
mcoc01522
Endocrine resistance
mcoc01524
Platinum drug resistance
mcoc04012
ErbB signaling pathway
mcoc04014
Ras signaling pathway
mcoc04015
Rap1 signaling pathway
mcoc04024
cAMP signaling pathway
mcoc04062
Chemokine signaling pathway
mcoc04066
HIF-1 signaling pathway
mcoc04068
FoxO signaling pathway
mcoc04070
Phosphatidylinositol signaling system
mcoc04071
Sphingolipid signaling pathway
mcoc04072
Phospholipase D signaling pathway
mcoc04081
Hormone signaling
mcoc04140
Autophagy - animal
mcoc04150
mTOR signaling pathway
mcoc04151
PI3K-Akt signaling pathway
mcoc04152
AMPK signaling pathway
mcoc04210
Apoptosis
mcoc04211
Longevity regulating pathway
mcoc04213
Longevity regulating pathway - multiple species
mcoc04218
Cellular senescence
mcoc04360
Axon guidance
mcoc04370
VEGF signaling pathway
mcoc04380
Osteoclast differentiation
mcoc04510
Focal adhesion
mcoc04550
Signaling pathways regulating pluripotency of stem cells
mcoc04611
Platelet activation
mcoc04613
Neutrophil extracellular trap formation
mcoc04620
Toll-like receptor signaling pathway
mcoc04625
C-type lectin receptor signaling pathway
mcoc04630
JAK-STAT signaling pathway
mcoc04650
Natural killer cell mediated cytotoxicity
mcoc04660
T cell receptor signaling pathway
mcoc04662
B cell receptor signaling pathway
mcoc04664
Fc epsilon RI signaling pathway
mcoc04666
Fc gamma R-mediated phagocytosis
mcoc04668
TNF signaling pathway
mcoc04670
Leukocyte transendothelial migration
mcoc04722
Neurotrophin signaling pathway
mcoc04725
Cholinergic synapse
mcoc04750
Inflammatory mediator regulation of TRP channels
mcoc04810
Regulation of actin cytoskeleton
mcoc04910
Insulin signaling pathway
mcoc04914
Progesterone-mediated oocyte maturation
mcoc04915
Estrogen signaling pathway
mcoc04917
Prolactin signaling pathway
mcoc04919
Thyroid hormone signaling pathway
mcoc04923
Regulation of lipolysis in adipocytes
mcoc04926
Relaxin signaling pathway
mcoc04929
GnRH secretion
mcoc04930
Type II diabetes mellitus
mcoc04931
Insulin resistance
mcoc04932
Non-alcoholic fatty liver disease
mcoc04933
AGE-RAGE signaling pathway in diabetic complications
mcoc04935
Growth hormone synthesis, secretion and action
mcoc04960
Aldosterone-regulated sodium reabsorption
mcoc04973
Carbohydrate digestion and absorption
mcoc05010
Alzheimer disease
mcoc05017
Spinocerebellar ataxia
mcoc05020
Prion disease
mcoc05100
Bacterial invasion of epithelial cells
mcoc05135
Yersinia infection
mcoc05142
Chagas disease
mcoc05146
Amoebiasis
mcoc05160
Hepatitis C
mcoc05161
Hepatitis B
mcoc05162
Measles
mcoc05163
Human cytomegalovirus infection
mcoc05164
Influenza A
mcoc05165
Human papillomavirus infection
mcoc05166
Human T-cell leukemia virus 1 infection
mcoc05167
Kaposi sarcoma-associated herpesvirus infection
mcoc05168
Herpes simplex virus 1 infection
mcoc05169
Epstein-Barr virus infection
mcoc05170
Human immunodeficiency virus 1 infection
mcoc05171
Coronavirus disease - COVID-19
mcoc05200
Pathways in cancer
mcoc05203
Viral carcinogenesis
mcoc05205
Proteoglycans in cancer
mcoc05206
MicroRNAs in cancer
mcoc05207
Chemical carcinogenesis - receptor activation
mcoc05208
Chemical carcinogenesis - reactive oxygen species
mcoc05210
Colorectal cancer
mcoc05211
Renal cell carcinoma
mcoc05212
Pancreatic cancer
mcoc05213
Endometrial cancer
mcoc05214
Glioma
mcoc05215
Prostate cancer
mcoc05218
Melanoma
mcoc05220
Chronic myeloid leukemia
mcoc05221
Acute myeloid leukemia
mcoc05222
Small cell lung cancer
mcoc05223
Non-small cell lung cancer
mcoc05224
Breast cancer
mcoc05225
Hepatocellular carcinoma
mcoc05226
Gastric cancer
mcoc05230
Central carbon metabolism in cancer
mcoc05231
Choline metabolism in cancer
mcoc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mcoc05415
Diabetic cardiomyopathy
mcoc05417
Lipid and atherosclerosis
mcoc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
116069491 (Pik3r2)
04015 Rap1 signaling pathway
116069491 (Pik3r2)
04630 JAK-STAT signaling pathway
116069491 (Pik3r2)
04668 TNF signaling pathway
116069491 (Pik3r2)
04066 HIF-1 signaling pathway
116069491 (Pik3r2)
04068 FoxO signaling pathway
116069491 (Pik3r2)
04070 Phosphatidylinositol signaling system
116069491 (Pik3r2)
04072 Phospholipase D signaling pathway
116069491 (Pik3r2)
04071 Sphingolipid signaling pathway
116069491 (Pik3r2)
04024 cAMP signaling pathway
116069491 (Pik3r2)
04151 PI3K-Akt signaling pathway
116069491 (Pik3r2)
04152 AMPK signaling pathway
116069491 (Pik3r2)
04150 mTOR signaling pathway
116069491 (Pik3r2)
09133 Signaling molecules and interaction
04081 Hormone signaling
116069491 (Pik3r2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
116069491 (Pik3r2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
116069491 (Pik3r2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
116069491 (Pik3r2)
04613 Neutrophil extracellular trap formation
116069491 (Pik3r2)
04620 Toll-like receptor signaling pathway
116069491 (Pik3r2)
04650 Natural killer cell mediated cytotoxicity
116069491 (Pik3r2)
04660 T cell receptor signaling pathway
116069491 (Pik3r2)
04662 B cell receptor signaling pathway
116069491 (Pik3r2)
04664 Fc epsilon RI signaling pathway
116069491 (Pik3r2)
04666 Fc gamma R-mediated phagocytosis
116069491 (Pik3r2)
04670 Leukocyte transendothelial migration
116069491 (Pik3r2)
04062 Chemokine signaling pathway
116069491 (Pik3r2)
09152 Endocrine system
04923 Regulation of lipolysis in adipocytes
116069491 (Pik3r2)
04929 GnRH secretion
116069491 (Pik3r2)
04915 Estrogen signaling pathway
116069491 (Pik3r2)
04917 Prolactin signaling pathway
116069491 (Pik3r2)
04926 Relaxin signaling pathway
116069491 (Pik3r2)
04935 Growth hormone synthesis, secretion and action
116069491 (Pik3r2)
04919 Thyroid hormone signaling pathway
116069491 (Pik3r2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
116069491 (Pik3r2)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
116069491 (Pik3r2)
09156 Nervous system
04725 Cholinergic synapse
116069491 (Pik3r2)
04722 Neurotrophin signaling pathway
116069491 (Pik3r2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
116069491 (Pik3r2)
09158 Development and regeneration
04360 Axon guidance
116069491 (Pik3r2)
04380 Osteoclast differentiation
116069491 (Pik3r2)
09149 Aging
04211 Longevity regulating pathway
116069491 (Pik3r2)
04213 Longevity regulating pathway - multiple species
116069491 (Pik3r2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116069491 (Pik3r2)
05206 MicroRNAs in cancer
116069491 (Pik3r2)
05205 Proteoglycans in cancer
116069491 (Pik3r2)
05207 Chemical carcinogenesis - receptor activation
116069491 (Pik3r2)
05208 Chemical carcinogenesis - reactive oxygen species
116069491 (Pik3r2)
05203 Viral carcinogenesis
116069491 (Pik3r2)
05230 Central carbon metabolism in cancer
116069491 (Pik3r2)
05231 Choline metabolism in cancer
116069491 (Pik3r2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
116069491 (Pik3r2)
09162 Cancer: specific types
05210 Colorectal cancer
116069491 (Pik3r2)
05212 Pancreatic cancer
116069491 (Pik3r2)
05225 Hepatocellular carcinoma
116069491 (Pik3r2)
05226 Gastric cancer
116069491 (Pik3r2)
05214 Glioma
116069491 (Pik3r2)
05221 Acute myeloid leukemia
116069491 (Pik3r2)
05220 Chronic myeloid leukemia
116069491 (Pik3r2)
05218 Melanoma
116069491 (Pik3r2)
05211 Renal cell carcinoma
116069491 (Pik3r2)
05215 Prostate cancer
116069491 (Pik3r2)
05213 Endometrial cancer
116069491 (Pik3r2)
05224 Breast cancer
116069491 (Pik3r2)
05222 Small cell lung cancer
116069491 (Pik3r2)
05223 Non-small cell lung cancer
116069491 (Pik3r2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
116069491 (Pik3r2)
05170 Human immunodeficiency virus 1 infection
116069491 (Pik3r2)
05161 Hepatitis B
116069491 (Pik3r2)
05160 Hepatitis C
116069491 (Pik3r2)
05171 Coronavirus disease - COVID-19
116069491 (Pik3r2)
05164 Influenza A
116069491 (Pik3r2)
05162 Measles
116069491 (Pik3r2)
05163 Human cytomegalovirus infection
116069491 (Pik3r2)
05167 Kaposi sarcoma-associated herpesvirus infection
116069491 (Pik3r2)
05169 Epstein-Barr virus infection
116069491 (Pik3r2)
05165 Human papillomavirus infection
116069491 (Pik3r2)
09171 Infectious disease: bacterial
05135 Yersinia infection
116069491 (Pik3r2)
05100 Bacterial invasion of epithelial cells
116069491 (Pik3r2)
09174 Infectious disease: parasitic
05146 Amoebiasis
116069491 (Pik3r2)
05142 Chagas disease
116069491 (Pik3r2)
09164 Neurodegenerative disease
05010 Alzheimer disease
116069491 (Pik3r2)
05017 Spinocerebellar ataxia
116069491 (Pik3r2)
05020 Prion disease
116069491 (Pik3r2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
116069491 (Pik3r2)
05418 Fluid shear stress and atherosclerosis
116069491 (Pik3r2)
05415 Diabetic cardiomyopathy
116069491 (Pik3r2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
116069491 (Pik3r2)
04932 Non-alcoholic fatty liver disease
116069491 (Pik3r2)
04931 Insulin resistance
116069491 (Pik3r2)
04933 AGE-RAGE signaling pathway in diabetic complications
116069491 (Pik3r2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116069491 (Pik3r2)
01524 Platinum drug resistance
116069491 (Pik3r2)
01522 Endocrine resistance
116069491 (Pik3r2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mcoc04131
]
116069491 (Pik3r2)
Membrane trafficking [BR:
mcoc04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
116069491 (Pik3r2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
RhoGAP
SH2_1
Ribosomal_L22e
SH3_1
SH3_9
Motif
Other DBs
NCBI-GeneID:
116069491
NCBI-ProteinID:
XP_031196021
LinkDB
All DBs
Position
Unknown
AA seq
722 aa
AA seq
DB search
MAGAEGFQYRAVYPFRRERPEDLELLPGDLLVVSRVALQALGVADGGERCPHNVGWMPGF
NERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPLDGPPESGHVLPDLAEQFSP
PDPAPPILVKLVEAIEQAELDSECYSRPELPAPRTDWSLSDLEQWDRTTLYDAVKGFLLA
LPAAVVTPEAAAEAYRTLREVAGPVGLVLEPPTLPLHQALTLRFLLQHLGRVARRAPSPA
TAVHALASAFGPLLLRSPPPGGEGDGSEPVPDFPVLLLERLVQEHVEERDAAPPALPPKP
SKAKLAPTALANGASPPSLQDAEWYWGDISREEVNERLRDTPDGTFLVRDASSKIQGEYT
LTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVELISHYRHESLAQYNAKLDTRLLYPVS
KYQQDQVVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNE
TIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQDL
RAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQRKINEWLGIKNETEDQYS
LMEDEDALPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTK
HCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPA
AR
NT seq
2169 nt
NT seq
+upstream
nt +downstream
nt
atggcaggtgctgagggcttccagtacagggctgtgtacccattccgccgggaacggcct
gaggacctggagctgctccctggtgacctcctggtggtgagccgggtggccctgcaggca
cttggtgtggctgatggaggagagcgctgcccacacaacgtgggctggatgcctggcttc
aacgagcgcaccagacagcgaggggacttccctggaacatatgtggagttcctaggacct
gtggctctggctcgaccaggccctcgcccacggggtccccgtccgttgcccgccaggccc
ttggatggacctcctgagtcaggccatgtgctcccagacctggcagagcagttctcccca
cctgaccctgctcccccgattctggtgaagctggtagaagccattgagcaagcagagctg
gacagtgaatgctacagtaggccggagctgcccgcaccacggacagactggtccctgagt
gacttggagcagtgggaccgcaccaccttgtacgatgctgttaagggcttccttctggcg
ttgcctgcagccgtggtgacccctgaagctgcagcagaggcgtatcggacactgcgggag
gttgcaggccctgtggggctggtgctggaacccccgacactgcctctgcaccaggcgctc
acgttgcggttcctgctgcagcacctgggccgcgtggcccgcagagcgccctcgccagct
acagctgtccatgcactggccagcgccttcgggccgctgctgctgcgttcacctccgcca
gggggcgagggtgatgggagtgagcccgtacccgacttccctgtgctgctgctagagagg
ctggtgcaggagcacgtggaggagcgagatgctgcgcccccagcactgccacccaaaccc
tctaaggcaaagctggcacctacagctctggccaatggagcaagcccaccctcgcttcag
gatgcagagtggtactggggggacatctccagggaagaggtgaatgagaggctccgggac
acacctgatggtaccttcttagtccgagatgcatccagcaagatccaaggagagtacaca
ctcaccctcaggaaaggcgggaacaacaagctgatcaaagtcttccaccgagatggtcac
tatggcttctcagagccccttaccttctgctccgtggtagaactcatctcccactaccgc
cacgagtcattggcccagtacaacgccaagctggacacgcgccttctctaccctgtgtcc
aaataccaacaagaccaggtggtgaaggaggacagcgtagaggctgtgggcgcccagctc
aaggtctaccaccagcagtaccaggacaagagccgcgaatacgaccagctatatgaagaa
tacacacggacctcccaggagcttcagatgaagcgcacagccatagaggccttcaacgag
accatcaagatcttcgaagaacagggccagacacaggagaagtgcagcaaggagtatttg
gagcgcttccggcgagagggcaatgagaaggagatgcagaggatcctgctgaactcggag
cgactcaagtctcgaatcgcggagatacacgaaagccgcacgaagctggagcaggatctg
cgggcgcaggcctcagacaaccgtgagatcgacaagcgcatgaacagcctcaagcctgac
ctcatgcagttgcgcaagatcagggaccagtacctcgtatggctcacccagaaaggtgcc
cgacagaggaagatcaacgaatggctgggaatcaagaacgagactgaggaccagtattcc
ctgatggaggatgaggatgccctcccccaccacgaggagcgcacatggtacgtgggcaag
atcaaccgcacacaggcggaggagatgctgagtggcaaacgagacgggaccttcctcatc
cgggagagcagccagcggggctgttacgcatgctccgtggtggtggacggcgacacgaag
cactgtgtcatctaccgcacggccaccggcttcggcttcgcagagccctataacctgtac
gggtccctgaaggagctggtgttgcactaccagcacgcatcgcttgtgcagcacaatgac
gcgctcaccgtcaccctcgcacaccctgtgcgtgcccctgggcctggcccgccgcctgca
gcacgctga
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