KEGG   Mastomys coucha (southern multimammate mouse): 116076719
Entry
116076719         CDS       T07224                                 
Symbol
Grb2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
mcoc  Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01521  EGFR tyrosine kinase inhibitor resistance
mcoc01522  Endocrine resistance
mcoc04010  MAPK signaling pathway
mcoc04012  ErbB signaling pathway
mcoc04014  Ras signaling pathway
mcoc04062  Chemokine signaling pathway
mcoc04068  FoxO signaling pathway
mcoc04072  Phospholipase D signaling pathway
mcoc04150  mTOR signaling pathway
mcoc04151  PI3K-Akt signaling pathway
mcoc04380  Osteoclast differentiation
mcoc04510  Focal adhesion
mcoc04540  Gap junction
mcoc04550  Signaling pathways regulating pluripotency of stem cells
mcoc04630  JAK-STAT signaling pathway
mcoc04650  Natural killer cell mediated cytotoxicity
mcoc04660  T cell receptor signaling pathway
mcoc04662  B cell receptor signaling pathway
mcoc04664  Fc epsilon RI signaling pathway
mcoc04714  Thermogenesis
mcoc04722  Neurotrophin signaling pathway
mcoc04910  Insulin signaling pathway
mcoc04912  GnRH signaling pathway
mcoc04915  Estrogen signaling pathway
mcoc04917  Prolactin signaling pathway
mcoc04926  Relaxin signaling pathway
mcoc04935  Growth hormone synthesis, secretion and action
mcoc05034  Alcoholism
mcoc05160  Hepatitis C
mcoc05161  Hepatitis B
mcoc05163  Human cytomegalovirus infection
mcoc05165  Human papillomavirus infection
mcoc05200  Pathways in cancer
mcoc05203  Viral carcinogenesis
mcoc05205  Proteoglycans in cancer
mcoc05206  MicroRNAs in cancer
mcoc05207  Chemical carcinogenesis - receptor activation
mcoc05208  Chemical carcinogenesis - reactive oxygen species
mcoc05210  Colorectal cancer
mcoc05211  Renal cell carcinoma
mcoc05213  Endometrial cancer
mcoc05214  Glioma
mcoc05215  Prostate cancer
mcoc05220  Chronic myeloid leukemia
mcoc05221  Acute myeloid leukemia
mcoc05223  Non-small cell lung cancer
mcoc05224  Breast cancer
mcoc05225  Hepatocellular carcinoma
mcoc05226  Gastric cancer
mcoc05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mcoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    116076719 (Grb2)
   04630 JAK-STAT signaling pathway
    116076719 (Grb2)
   04068 FoxO signaling pathway
    116076719 (Grb2)
   04072 Phospholipase D signaling pathway
    116076719 (Grb2)
   04151 PI3K-Akt signaling pathway
    116076719 (Grb2)
   04150 mTOR signaling pathway
    116076719 (Grb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    116076719 (Grb2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    116076719 (Grb2)
   04660 T cell receptor signaling pathway
    116076719 (Grb2)
   04662 B cell receptor signaling pathway
    116076719 (Grb2)
   04664 Fc epsilon RI signaling pathway
    116076719 (Grb2)
   04062 Chemokine signaling pathway
    116076719 (Grb2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    116076719 (Grb2)
   04917 Prolactin signaling pathway
    116076719 (Grb2)
   04926 Relaxin signaling pathway
    116076719 (Grb2)
   04935 Growth hormone synthesis, secretion and action
    116076719 (Grb2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    116076719 (Grb2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    116076719 (Grb2)
  09159 Environmental adaptation
   04714 Thermogenesis
    116076719 (Grb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116076719 (Grb2)
   05206 MicroRNAs in cancer
    116076719 (Grb2)
   05205 Proteoglycans in cancer
    116076719 (Grb2)
   05207 Chemical carcinogenesis - receptor activation
    116076719 (Grb2)
   05208 Chemical carcinogenesis - reactive oxygen species
    116076719 (Grb2)
   05203 Viral carcinogenesis
    116076719 (Grb2)
   05231 Choline metabolism in cancer
    116076719 (Grb2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    116076719 (Grb2)
   05225 Hepatocellular carcinoma
    116076719 (Grb2)
   05226 Gastric cancer
    116076719 (Grb2)
   05214 Glioma
    116076719 (Grb2)
   05221 Acute myeloid leukemia
    116076719 (Grb2)
   05220 Chronic myeloid leukemia
    116076719 (Grb2)
   05211 Renal cell carcinoma
    116076719 (Grb2)
   05215 Prostate cancer
    116076719 (Grb2)
   05213 Endometrial cancer
    116076719 (Grb2)
   05224 Breast cancer
    116076719 (Grb2)
   05223 Non-small cell lung cancer
    116076719 (Grb2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    116076719 (Grb2)
   05160 Hepatitis C
    116076719 (Grb2)
   05163 Human cytomegalovirus infection
    116076719 (Grb2)
   05165 Human papillomavirus infection
    116076719 (Grb2)
  09165 Substance dependence
   05034 Alcoholism
    116076719 (Grb2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    116076719 (Grb2)
   01522 Endocrine resistance
    116076719 (Grb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mcoc04131]
    116076719 (Grb2)
Membrane trafficking [BR:mcoc04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    116076719 (Grb2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 DUF7145 SH2_2 DUF5093 hSH3 SH3_4 DUF7063
Other DBs
NCBI-GeneID: 116076719
NCBI-ProteinID: XP_031206395
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRSV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgctgacgatgagctgagcttcaaa
aggggggacatccttaaggttttgaatgaagaatgtgatcagaactggtataaggcagaa
ctcaatgggaaagatggcttcatccccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgat
ggggccttcctgatccgagagagtgagagtgctcctggggacttctccctgtctgtcaag
tttggaaatgatgtgcagcacttcaaggtgctccgtgacggagccgggaagtatttcctg
tgggtggtgaagtttaactctttgaatgagctggtagattaccacagatcaacatccgtg
tccaggaaccagcagatattcttacgggacatagaacaggtgccacagcagccaacgtat
gtccaggcactctttgactttgacccccaggaggatggcgagctgggctttcgcagagga
gacttcattcacgtcatggataactcagatcccaattggtggaaaggggcctgccatggg
cagaccggcatgtttccccgcaattatgtcaccccagtgaaccggagcgtctaa

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