KEGG   Mastomys coucha (southern multimammate mouse): 116096465
Entry
116096465         CDS       T07224                                 
Symbol
Pik3r3
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
mcoc  Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01521  EGFR tyrosine kinase inhibitor resistance
mcoc01522  Endocrine resistance
mcoc01524  Platinum drug resistance
mcoc04012  ErbB signaling pathway
mcoc04014  Ras signaling pathway
mcoc04015  Rap1 signaling pathway
mcoc04024  cAMP signaling pathway
mcoc04062  Chemokine signaling pathway
mcoc04066  HIF-1 signaling pathway
mcoc04068  FoxO signaling pathway
mcoc04070  Phosphatidylinositol signaling system
mcoc04071  Sphingolipid signaling pathway
mcoc04072  Phospholipase D signaling pathway
mcoc04081  Hormone signaling
mcoc04140  Autophagy - animal
mcoc04150  mTOR signaling pathway
mcoc04151  PI3K-Akt signaling pathway
mcoc04152  AMPK signaling pathway
mcoc04210  Apoptosis
mcoc04211  Longevity regulating pathway
mcoc04213  Longevity regulating pathway - multiple species
mcoc04218  Cellular senescence
mcoc04360  Axon guidance
mcoc04370  VEGF signaling pathway
mcoc04380  Osteoclast differentiation
mcoc04510  Focal adhesion
mcoc04550  Signaling pathways regulating pluripotency of stem cells
mcoc04611  Platelet activation
mcoc04613  Neutrophil extracellular trap formation
mcoc04620  Toll-like receptor signaling pathway
mcoc04625  C-type lectin receptor signaling pathway
mcoc04630  JAK-STAT signaling pathway
mcoc04650  Natural killer cell mediated cytotoxicity
mcoc04660  T cell receptor signaling pathway
mcoc04662  B cell receptor signaling pathway
mcoc04664  Fc epsilon RI signaling pathway
mcoc04666  Fc gamma R-mediated phagocytosis
mcoc04668  TNF signaling pathway
mcoc04670  Leukocyte transendothelial migration
mcoc04722  Neurotrophin signaling pathway
mcoc04725  Cholinergic synapse
mcoc04750  Inflammatory mediator regulation of TRP channels
mcoc04810  Regulation of actin cytoskeleton
mcoc04910  Insulin signaling pathway
mcoc04914  Progesterone-mediated oocyte maturation
mcoc04915  Estrogen signaling pathway
mcoc04917  Prolactin signaling pathway
mcoc04919  Thyroid hormone signaling pathway
mcoc04923  Regulation of lipolysis in adipocytes
mcoc04926  Relaxin signaling pathway
mcoc04929  GnRH secretion
mcoc04930  Type II diabetes mellitus
mcoc04931  Insulin resistance
mcoc04932  Non-alcoholic fatty liver disease
mcoc04933  AGE-RAGE signaling pathway in diabetic complications
mcoc04935  Growth hormone synthesis, secretion and action
mcoc04960  Aldosterone-regulated sodium reabsorption
mcoc04973  Carbohydrate digestion and absorption
mcoc05010  Alzheimer disease
mcoc05017  Spinocerebellar ataxia
mcoc05020  Prion disease
mcoc05100  Bacterial invasion of epithelial cells
mcoc05135  Yersinia infection
mcoc05142  Chagas disease
mcoc05146  Amoebiasis
mcoc05160  Hepatitis C
mcoc05161  Hepatitis B
mcoc05162  Measles
mcoc05163  Human cytomegalovirus infection
mcoc05164  Influenza A
mcoc05165  Human papillomavirus infection
mcoc05166  Human T-cell leukemia virus 1 infection
mcoc05167  Kaposi sarcoma-associated herpesvirus infection
mcoc05168  Herpes simplex virus 1 infection
mcoc05169  Epstein-Barr virus infection
mcoc05170  Human immunodeficiency virus 1 infection
mcoc05171  Coronavirus disease - COVID-19
mcoc05200  Pathways in cancer
mcoc05203  Viral carcinogenesis
mcoc05205  Proteoglycans in cancer
mcoc05206  MicroRNAs in cancer
mcoc05207  Chemical carcinogenesis - receptor activation
mcoc05208  Chemical carcinogenesis - reactive oxygen species
mcoc05210  Colorectal cancer
mcoc05211  Renal cell carcinoma
mcoc05212  Pancreatic cancer
mcoc05213  Endometrial cancer
mcoc05214  Glioma
mcoc05215  Prostate cancer
mcoc05218  Melanoma
mcoc05220  Chronic myeloid leukemia
mcoc05221  Acute myeloid leukemia
mcoc05222  Small cell lung cancer
mcoc05223  Non-small cell lung cancer
mcoc05224  Breast cancer
mcoc05225  Hepatocellular carcinoma
mcoc05226  Gastric cancer
mcoc05230  Central carbon metabolism in cancer
mcoc05231  Choline metabolism in cancer
mcoc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mcoc05415  Diabetic cardiomyopathy
mcoc05417  Lipid and atherosclerosis
mcoc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    116096465 (Pik3r3)
   04014 Ras signaling pathway
    116096465 (Pik3r3)
   04015 Rap1 signaling pathway
    116096465 (Pik3r3)
   04370 VEGF signaling pathway
    116096465 (Pik3r3)
   04630 JAK-STAT signaling pathway
    116096465 (Pik3r3)
   04668 TNF signaling pathway
    116096465 (Pik3r3)
   04066 HIF-1 signaling pathway
    116096465 (Pik3r3)
   04068 FoxO signaling pathway
    116096465 (Pik3r3)
   04070 Phosphatidylinositol signaling system
    116096465 (Pik3r3)
   04072 Phospholipase D signaling pathway
    116096465 (Pik3r3)
   04071 Sphingolipid signaling pathway
    116096465 (Pik3r3)
   04024 cAMP signaling pathway
    116096465 (Pik3r3)
   04151 PI3K-Akt signaling pathway
    116096465 (Pik3r3)
   04152 AMPK signaling pathway
    116096465 (Pik3r3)
   04150 mTOR signaling pathway
    116096465 (Pik3r3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    116096465 (Pik3r3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116096465 (Pik3r3)
  09143 Cell growth and death
   04210 Apoptosis
    116096465 (Pik3r3)
   04218 Cellular senescence
    116096465 (Pik3r3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116096465 (Pik3r3)
   04550 Signaling pathways regulating pluripotency of stem cells
    116096465 (Pik3r3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116096465 (Pik3r3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    116096465 (Pik3r3)
   04613 Neutrophil extracellular trap formation
    116096465 (Pik3r3)
   04620 Toll-like receptor signaling pathway
    116096465 (Pik3r3)
   04625 C-type lectin receptor signaling pathway
    116096465 (Pik3r3)
   04650 Natural killer cell mediated cytotoxicity
    116096465 (Pik3r3)
   04660 T cell receptor signaling pathway
    116096465 (Pik3r3)
   04662 B cell receptor signaling pathway
    116096465 (Pik3r3)
   04664 Fc epsilon RI signaling pathway
    116096465 (Pik3r3)
   04666 Fc gamma R-mediated phagocytosis
    116096465 (Pik3r3)
   04670 Leukocyte transendothelial migration
    116096465 (Pik3r3)
   04062 Chemokine signaling pathway
    116096465 (Pik3r3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116096465 (Pik3r3)
   04923 Regulation of lipolysis in adipocytes
    116096465 (Pik3r3)
   04929 GnRH secretion
    116096465 (Pik3r3)
   04915 Estrogen signaling pathway
    116096465 (Pik3r3)
   04914 Progesterone-mediated oocyte maturation
    116096465 (Pik3r3)
   04917 Prolactin signaling pathway
    116096465 (Pik3r3)
   04926 Relaxin signaling pathway
    116096465 (Pik3r3)
   04935 Growth hormone synthesis, secretion and action
    116096465 (Pik3r3)
   04919 Thyroid hormone signaling pathway
    116096465 (Pik3r3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    116096465 (Pik3r3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    116096465 (Pik3r3)
  09156 Nervous system
   04725 Cholinergic synapse
    116096465 (Pik3r3)
   04722 Neurotrophin signaling pathway
    116096465 (Pik3r3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    116096465 (Pik3r3)
  09158 Development and regeneration
   04360 Axon guidance
    116096465 (Pik3r3)
   04380 Osteoclast differentiation
    116096465 (Pik3r3)
  09149 Aging
   04211 Longevity regulating pathway
    116096465 (Pik3r3)
   04213 Longevity regulating pathway - multiple species
    116096465 (Pik3r3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116096465 (Pik3r3)
   05206 MicroRNAs in cancer
    116096465 (Pik3r3)
   05205 Proteoglycans in cancer
    116096465 (Pik3r3)
   05207 Chemical carcinogenesis - receptor activation
    116096465 (Pik3r3)
   05208 Chemical carcinogenesis - reactive oxygen species
    116096465 (Pik3r3)
   05203 Viral carcinogenesis
    116096465 (Pik3r3)
   05230 Central carbon metabolism in cancer
    116096465 (Pik3r3)
   05231 Choline metabolism in cancer
    116096465 (Pik3r3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116096465 (Pik3r3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    116096465 (Pik3r3)
   05212 Pancreatic cancer
    116096465 (Pik3r3)
   05225 Hepatocellular carcinoma
    116096465 (Pik3r3)
   05226 Gastric cancer
    116096465 (Pik3r3)
   05214 Glioma
    116096465 (Pik3r3)
   05221 Acute myeloid leukemia
    116096465 (Pik3r3)
   05220 Chronic myeloid leukemia
    116096465 (Pik3r3)
   05218 Melanoma
    116096465 (Pik3r3)
   05211 Renal cell carcinoma
    116096465 (Pik3r3)
   05215 Prostate cancer
    116096465 (Pik3r3)
   05213 Endometrial cancer
    116096465 (Pik3r3)
   05224 Breast cancer
    116096465 (Pik3r3)
   05222 Small cell lung cancer
    116096465 (Pik3r3)
   05223 Non-small cell lung cancer
    116096465 (Pik3r3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    116096465 (Pik3r3)
   05170 Human immunodeficiency virus 1 infection
    116096465 (Pik3r3)
   05161 Hepatitis B
    116096465 (Pik3r3)
   05160 Hepatitis C
    116096465 (Pik3r3)
   05171 Coronavirus disease - COVID-19
    116096465 (Pik3r3)
   05164 Influenza A
    116096465 (Pik3r3)
   05162 Measles
    116096465 (Pik3r3)
   05168 Herpes simplex virus 1 infection
    116096465 (Pik3r3)
   05163 Human cytomegalovirus infection
    116096465 (Pik3r3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116096465 (Pik3r3)
   05169 Epstein-Barr virus infection
    116096465 (Pik3r3)
   05165 Human papillomavirus infection
    116096465 (Pik3r3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    116096465 (Pik3r3)
   05100 Bacterial invasion of epithelial cells
    116096465 (Pik3r3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    116096465 (Pik3r3)
   05142 Chagas disease
    116096465 (Pik3r3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    116096465 (Pik3r3)
   05017 Spinocerebellar ataxia
    116096465 (Pik3r3)
   05020 Prion disease
    116096465 (Pik3r3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116096465 (Pik3r3)
   05418 Fluid shear stress and atherosclerosis
    116096465 (Pik3r3)
   05415 Diabetic cardiomyopathy
    116096465 (Pik3r3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    116096465 (Pik3r3)
   04932 Non-alcoholic fatty liver disease
    116096465 (Pik3r3)
   04931 Insulin resistance
    116096465 (Pik3r3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    116096465 (Pik3r3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    116096465 (Pik3r3)
   01524 Platinum drug resistance
    116096465 (Pik3r3)
   01522 Endocrine resistance
    116096465 (Pik3r3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mcoc04131]
    116096465 (Pik3r3)
Membrane trafficking [BR:mcoc04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    116096465 (Pik3r3)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 Bap31_Bap29_C Transcrip_act Laminin_I
Other DBs
NCBI-GeneID: 116096465
NCBI-ProteinID: XP_031234141
LinkDB
Position
Unknown
AA seq 461 aa
MYNTVWNMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVTNGMKDSFVSL
QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
KYGFSEPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKN
LQEFHSQYQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKDY
IERFRREGNEKEIERIMMNYDKLKLRLGEIHDSKVRLEQDLKKQALDNREIDKKMNSIKP
DLIQLRKIRDQHLVWLNHRGVRQRRLNAWLGIKNEDLDESYFINEEDENLPHYDEKTWFV
EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
NT seq 1386 nt   +upstreamnt  +downstreamnt
atgtacaatacggtgtggaatatggaccgcgatgacgcagactggagggaggtgatgatg
ccctattcgacagaactgatattttatattgaaatggatcctccagctcttccaccaaag
ccacctaagccaatgacttcagcggttacaaatggaatgaaggacagtttcgtttctctt
caagatgcagagtggtactggggagatatttccagggaagaggtaaatgacaaattgcgc
gacatgccagatggcaccttcttagttcgtgatgcctcaacaaaaatgcagggggactat
acattgactttgaggaagggaggaaataataaattaataaagatctatcaccgggatggt
aaatacggcttttctgagcctctgacgtttaattctgtggtggagctcattaaccactat
catcacgaatctcttgctcagtacaatcctaaactcgatgtgaagctgatgtatccagta
tccagataccaacaggatcagttggtaaaagaagataacattgatgcagtaggtaaaaac
ctgcaagagttccactctcagtatcaggagaagagcagagagtacgacaggctgtatgaa
gagtacaccaggacgtcacaggaaatacaaatgaagaggactgctattgaagcctttaat
gaaacaattaaaatatttgaggagcagtgtcatactcaagaacaacacagtaaagactat
attgagcggtttcgcagagaggggaatgagaaagagattgagcgaattatgatgaattat
gataaattgaaattacgtcttggtgagattcatgatagcaaagtgcgtcttgagcaggac
ttgaagaaacaagctttggacaaccgggaaatagataaaaaaatgaatagcatcaaacct
gacctgatccagctgcgtaagatccgggatcagcatcttgtatggctcaatcacagagga
gtgaggcagaggcgcctgaatgcctggctggggatcaagaatgaggacttggatgaaagc
tattttatcaatgaggaagatgagaacctgccgcattatgatgagaaaacctggtttgtg
gaggatatcaaccgagtacaagcagaggacttgctttatgggaaaccagatggtgcattc
ttaattcgtgagagtagcaagaaaggatgttacgcttgttctgtggttgcagacggggaa
gtgaagcactgtgtcatctacagcactgctcgaggatatggctttgcagagccctacaac
ctgtacagctcactgaaggagctggtgctccattaccagcagacatccttggttcagcac
aatgactccctcaacgtcaggctcgcttaccctgtccatgcacagatgccttcgctctgc
agataa

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