Mastomys coucha (southern multimammate mouse): 116096709
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Entry
116096709 CDS
T07224
Symbol
Lck
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc04064
NF-kappa B signaling pathway
mcoc04380
Osteoclast differentiation
mcoc04517
IgSF CAM signaling
mcoc04650
Natural killer cell mediated cytotoxicity
mcoc04658
Th1 and Th2 cell differentiation
mcoc04659
Th17 cell differentiation
mcoc04660
T cell receptor signaling pathway
mcoc05135
Yersinia infection
mcoc05166
Human T-cell leukemia virus 1 infection
mcoc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mcoc05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
116096709 (Lck)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
116096709 (Lck)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
116096709 (Lck)
04660 T cell receptor signaling pathway
116096709 (Lck)
04658 Th1 and Th2 cell differentiation
116096709 (Lck)
04659 Th17 cell differentiation
116096709 (Lck)
09158 Development and regeneration
04380 Osteoclast differentiation
116096709 (Lck)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
116096709 (Lck)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
116096709 (Lck)
09171 Infectious disease: bacterial
05135 Yersinia infection
116096709 (Lck)
09163 Immune disease
05340 Primary immunodeficiency
116096709 (Lck)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcoc01001
]
116096709 (Lck)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mcoc03036
]
116096709 (Lck)
Enzymes [BR:
mcoc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
116096709 (Lck)
Protein kinases [BR:
mcoc01001
]
Non-receptor tyrosine kinases
SRC family
116096709 (Lck)
Chromosome and associated proteins [BR:
mcoc03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
116096709 (Lck)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH2_1
DUF7251
Haspin_kinase
SH3_16
Kdo
SH3_3
Motif
Other DBs
NCBI-GeneID:
116096709
NCBI-ProteinID:
XP_031234643
LinkDB
All DBs
Position
Unknown
AA seq
521 aa
AA seq
DB search
MGASELTISGIMGCVCSSNPEDDWMENIDVCENCHYPIVPLDSKTSLPIRNGSEVRDPLV
TYEGSLPPASPLQDNLVIALYSYEPTHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEG
FIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRD
FDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHDLVRHYTNASDGLCTKLSRPCQTQKP
QKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEA
NLMKQLQHPRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIA
EGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP
EAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEEL
YHLMMLCWKERPEERPTFDYLRSVLDDFFTATEGQYQPQPC
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgggggcctctgagctgacaatctcagggatcatgggctgtgtctgcagctcaaaccct
gaagatgactggatggagaacattgacgtgtgtgaaaactgccactatcccatagtcccc
ctggacagcaagacctcgttgcccatccggaatggctctgaagtacgggacccactggtc
acctatgagggctccctcccaccagcctccccactgcaagacaacctggttatcgccctg
tacagctatgagcccacccatgatggagacctgggctttgagaagggtgaacaactccga
atcctggagcagagcggtgagtggtggaaggctcagtccctgaccactggccaagaaggc
ttcatccccttcaacttcgtggcgaaagcaaacagcctggagcctgaaccttggttcttc
aagaatttgagccgtaaggacgccgagcggcagcttttggcgcccgggaacacgcatgga
tccttcctgatccgagaaagcgaaagcaccgccggatccttttcactatcggtcagagac
ttcgaccagaaccagggagaagtggtgaaacattacaagatccgtaacctagacaacggt
ggcttctacatctcccctcggatcacttttcccggactacacgatctggtccgccattac
accaacgcctctgatggactatgcacaaagttgagccgcccttgccagacccagaagccc
cagaaaccatggtgggaggacgaatgggaagttcccagggagacactgaagttggttgag
cggctgggagctggccagttcggggaagtgtggatggggtactacaacggacacacgaag
gtggcagtgaagagtctgaagcaagggagcatgtcccccgatgccttcctggctgaggct
aacctcatgaagcagctgcagcacccgcggctagtccggctttatgcagtggtcacccag
gagcccatctacattatcacagaatacatggagaacgggagcctagtagattttctcaag
actccctcgggcatcaagttgaacgtcaacaaacttttggacatggcagcccagattgca
gagggcatggcattcatcgaagagcagaattacatccatcgtgacctgcgggccgccaac
atcctggtgtctgacacgctgagctgcaagatcgcagactttggcctggcgcgcctcatt
gaggacaatgagtacacagcccgggagggggccaaatttcccatcaagtggacagcacca
gaagccattaactatggcaccttcaccatcaagtcggatgtgtggtccttcgggatcctg
ctgacagagattgtcactcatggtcgaatcccttacccaggaatgaccaaccctgaagtc
attcagaacctggagcgaggctaccgaatggtgcgacctgacaactgtccggaagagctg
taccacctcatgatgctgtgctggaaggagcgcccagaggaacggcccacatttgactac
cttcggagcgtcctggatgacttcttcacagccacagagggccagtaccagccccagcct
tgttag
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