Mastomys coucha (southern multimammate mouse): 116099474
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Entry
116099474 CDS
T07224
Symbol
Ret
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc04010
MAPK signaling pathway
mcoc04020
Calcium signaling pathway
mcoc04151
PI3K-Akt signaling pathway
mcoc05200
Pathways in cancer
mcoc05216
Thyroid cancer
mcoc05223
Non-small cell lung cancer
mcoc05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
116099474 (Ret)
04020 Calcium signaling pathway
116099474 (Ret)
04151 PI3K-Akt signaling pathway
116099474 (Ret)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116099474 (Ret)
05230 Central carbon metabolism in cancer
116099474 (Ret)
09162 Cancer: specific types
05216 Thyroid cancer
116099474 (Ret)
05223 Non-small cell lung cancer
116099474 (Ret)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcoc01001
]
116099474 (Ret)
Enzymes [BR:
mcoc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
116099474 (Ret)
Protein kinases [BR:
mcoc01001
]
Receptor tyrosine kinases (RTK)
RET family
116099474 (Ret)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
RET_CLD3
Pkinase
RET_CRD
Cadherin
Pkinase_fungal
Haspin_kinase
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
116099474
NCBI-ProteinID:
XP_031238967
LinkDB
All DBs
Position
Unknown
AA seq
1115 aa
AA seq
DB search
MAKATSGAAGLGLKLVLLLPLLGEAPLGLYFSRDAYWERLYVDQPAGTPLLYVHALRDAT
GEVPSFRLSQHLYGVYRTRLHENDWIRINETTGLLYLNQSLDHSSWEQLSIRNGGFPLLT
IFLQVFLGSTAQREGECHWPGCVRVYFSFINDTFPNCSSFKAQDLCIPETDVSFRIRENR
PPGTFYHFHRLPVQFLCPNISVEYSLLEGDSLPFRCDPDCLEVSTLWALDRELREKYVLE
AECTVVGTGANKEKMTVSFPVTVYDEDDSAPAFSGGVGTASAVVEFKRKEGTVVATLQVF
DADVVPASGELVRRYTCTLLSGDSWAQQTFRVEHSPIETLVQSNNNSVRATMHNYKLVLN
RSLSISESRVLQLVVLVNDSDFLGPGAGVLFLHFNVSVLPVTLNLPKTYSFPVNRRARRY
AQIGKVCVENCQEFTGVSVQYKLQPSSTNCTVLGVVTSPEDTSGTLFVNDTEALRRPECT
ELQYTVVATDRQTRRQTQASLVVAVEGMSIAEEVGCPKSCAVNKRRPECEECGGLGSPTG
RCEWRQGDGKGITRNFSTCSPSIRTCPDGHCDAVESRDVNICPQDCLRADIVGGHERGER
QGIKAGYGICNCFPDEKKCFCEPEDSQGPLCDELCRTVITAAVLFTFIISVLLSTFCIHR
YHKHAHKPPIASAEMTFCRPAQGFPVSYSSSGTRRPSLDSMENQVSMDSLKIQEDPKWEF
PRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLHSEFNLL
KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYMSGGGNRNSSSLD
HPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDV
YEEDSYVKKSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPER
LFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPLFADISKDLEKMMVKSRDYLDLA
ASTPSDSLLYDDGLSEEETPLVDCNNAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTR
ADGTSTGFPRYANDSVYANWMVSPSAAKLMDTFDS
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaagcgacgtccggcgccgcagggctggggctgaagctggttttgctgctgccg
ctgctaggagaagccccactgggcctctacttctcaagggatgcttactgggagaggctg
tatgtggaccagccagctggcacacctctactctatgtccatgccctacgggatgccact
ggagaagtgccgagcttccgcctgagccagcatctctacggcgtctaccgaacacggctg
catgagaatgactggatccgcatcaatgagactactggccttctctacctcaatcagagc
ctggaccacagttcctgggaacagctcagcatccgcaatggcggcttccccttgctcact
atcttcctccaggtctttctggggtccacagcccagagagagggagaatgccattggcca
ggctgtgtccgtgtatacttctccttcatcaacgacaccttcccaaattgtagctccttc
aaggcccaggatctctgcatcccggagacagatgtgtccttccgcatcagggagaacagg
ccccctggcaccttctaccatttccacaggttacctgtgcagtttctttgtcccaacatc
agtgtggaatacagtctcttagaaggggacagtctgcccttccgttgtgacccagactgc
ctggaagtgagcactctctgggccctggatcgagagcttcgggagaagtatgtgctagag
gctgagtgcacagtagtaggcactggtgccaacaaagagaagatgaccgtgtccttcccg
gtgacagtgtacgatgaggacgactcggcgcctgccttctccggaggtgtgggcactgcc
agtgctgtggtggagtttaagcggaaggagggcactgtggtggccactctgcaggtgttt
gatgcagatgtggtgccggcatctggggagctggtgagacggtacacatgcacactactc
tccggagactcctgggcccagcagaccttccgggtggagcactcgcccatcgagaccctg
gtccagtccaacaacaactccgtgcgggcaaccatgcacaattacaagcttgttctcaac
aggagcctctctatctcagagagccgagtcttgcagctagtggtcctggtcaatgactca
gacttcctggggcctggggcaggtgtcctcttcctccatttcaatgtgtctgtgctgcct
gtcaccctgaacctacccaagacctactccttcccagtgaataggagggcccgccgttat
gcccagatcgggaaagtctgtgtggaaaactgccaggagttcacaggtgtctccgtccag
tacaagctgcagccctccagcaccaactgcactgtcctaggtgtggtcacctcacccgag
gacacctcggggaccctatttgtaaatgacacggaggccctgcggcgacctgagtgcact
gagcttcagtacacggtggtagccactgaccgtcagacccgcaggcagacccaggcttcg
ttagttgtcgcagtggaggggatgtctattgctgaagaagtgggctgccccaagtcctgt
gcagtaaacaagaggcgacctgagtgtgaggagtgcggtggcttgggctctccaactggc
agatgcgagtggcgtcagggagatggtaaagggatcaccaggaacttctccacctgctcc
cccagtatcaggacctgccctgatggccactgtgatgctgtggagagccgggatgtcaac
atctgtccccaggactgtctccgtgccgacattgttggggggcatgagcgaggggagcgc
caggggattaaggctggctatggcatctgcaactgtttccccgatgagaagaagtgcttc
tgtgagccggaggacagtcagggccctttgtgtgatgagttgtgccgtacggtcatcaca
gctgctgtcctcttcacctttatcatctctgtcctgctgtccaccttctgcatccaccgc
taccacaagcatgcgcacaagccacccatcgcatcagcagaaatgaccttctgccggcca
gcccagggcttcccagtcagctattcctcttcaggcacccgccggccttccctggattcc
atggagaaccaggtctctatggactctttaaagatccaggaggatccaaagtgggaattt
cctcggaagaacttagttcttgggaaaaccctgggagaaggcgagtttggaaaagtcgtc
aaggccacagccttccgtctgaaaggccgggcaggatacaccacagtggctgtgaaaatg
ctgaaagaaaacgcctcccagagtgaattacgagacctgcactctgagttcaaccttctg
aaacaagtcaaccatccacatgtcatcaagttgtatggggcctgcagccaggatggtcca
cttcttctcatcgtggagtatgccaagtatggctccttacggggattcctccgggacagc
cgcaagatcgggcctgcctatatgagcggtggaggcaaccgcaattccagctccctggac
cacccagatgaaagggtactgaccatgggtgacctcatctccttcgcctggcagatctca
aggggtatgcagtacttggctgaaatgaagctcgtacaccgggatttagctgccagaaac
atcttggtggccgagggacggaagatgaagatttccgacttcgggctgtcccgagatgtt
tatgaagaagattcctatgtgaagaaaagcaagggccggattcccgtcaaatggatggca
attgagtccctttttgatcacatctataccactcaaagcgatgtgtggtcctttggtgtg
ctgctctgggaaattgtgaccctgggaggcaacccctaccctggaattcctcctgagcga
ctcttcaaccttctcaagacgggccataggatggagaggccggacaactgcagtgaggaa
atgtaccgcctgatgctgcagtgctggaagcaggagccagacaagaggccattgtttgct
gacatcagcaaggatctggagaagatgatggtcaagagcagagactacttggacctggct
gcatccaccccttcagactcactgctctatgatgatgggctctcagaagaggagacgccc
ctggtggactgtaacaatgctcccctcccgcgctccctcccttccacatggattgaaaac
aaactctatggcatgtcagacccgaactggcctggagagagtcctgtaccactcacgaga
gccgatggcactagcactgggttcccaagatatgcaaatgatagtgtatatgctaactgg
atggtttcaccctcagcggcaaaattaatggacacatttgatagctaa
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