Micromonospora craniellae: ID554_20380
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Entry
ID554_20380 CDS
T06957
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mcra
Micromonospora craniellae
Pathway
mcra00020
Citrate cycle (TCA cycle)
mcra00630
Glyoxylate and dicarboxylate metabolism
mcra00785
Lipoic acid metabolism
mcra01100
Metabolic pathways
mcra01110
Biosynthesis of secondary metabolites
mcra01120
Microbial metabolism in diverse environments
mcra01200
Carbon metabolism
mcra01210
2-Oxocarboxylic acid metabolism
Module
mcra_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mcra_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mcra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ID554_20380
00630 Glyoxylate and dicarboxylate metabolism
ID554_20380
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ID554_20380
Enzymes [BR:
mcra01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
ID554_20380
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
ID554_20380
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
ID554_20380
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
ID554_20380
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QOC90512
LinkDB
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Position
complement(4476396..4480148)
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AA seq
1250 aa
AA seq
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MSTQQTSQENPLAGFGPNEWIVEEMYQRYLADPSSVDPAWHDFFADYRPGAGKARSADGD
GQATGTESTPKAPAKAEPSAKAELAAKAEPAPAKSTAPAKSTAPAKAKPAAKSEPAKTTS
AKSAPTKSAPTATGPQTTPLRGVAARIVQNMDASLAVPTATSVRAVPAKLLVDNRIVINN
HLARGRGGKVSFTHLVGYALVRAMVAHPEMNNSFAEVDGKPAMVRPEHVNLGIAIDLAKP
DGSRTLVVPSIKGCEQMDFRQFWQAYEDIVRRARRNELTMDDYSGTTISLTNPGGIGTVH
SMPRLMQGQSAIIGVGAMEYPAPYQGMSEATLAELAVSKVITLTSTYDHRIIQGAQSGEF
LKVMHELLLGEHGYYDQIFTSLRIPYEPVRWMRDVAVDSEGQINKTARVHELIHSYRVRG
HLMADTDPLEFKIRKHPDLDVLQHGLTLWDLDRTFPVNGFNGRQRMRLREILGVLRDSYC
RRVGIEYMHIQDPAERRWIQERVERKYEKPPADEQKHVLNRLNAAEAFETFLQTKYVGQK
RFSLEGGESLIPLLGEVLEASAENDLDEVVIGMAHRGRLNVLANIVGKPYEKIFSEFEGH
LDPRSTQGSGDVKYHLGQNGKFTTPDGDHSVKVSVVANPSHLEAVDPVLEGIVRAKQDRI
DLKLEGYTVLPLAVHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVGFTTAPEY
SRSSLYSTDVARMIQAPIFHVNGDDPEAVVRVARLAFEYRQTFNKDVVIDLVCYRRRGHN
EGDDPSMSNPQMYKIIDSKRSVRKLYTEELIGRGDITVEDAEELLRDYQAQLERVFKATR
DAASTPRQVSRPARQDEPEPQVETATEASVIKAIGEAHVNLPDGFTPHKRIQQLLDRRAR
MSVEGTIDWGFGEIIAFGALLHDGVTVRLAGQDSRRGTFVQRHASVVDSETGDDYLPLQS
LTGNGERSRFFAHDSLLSEYAAMGFEYGYSVENLNALVCWEAQFGDFVNGAQSVIDEFIS
SGEVKWGQRSAVTLLLPHGHEGQGPDHTSGRPERFLQLCAEDNMRVSIPTTPANYFHLLR
RQALSPKRKPLVVFTPKSLLRHKLCVSSVEDFTSGTFSPVLSDQAAPAPEQVKRVLLCSG
KVYYDLFQARQERSVTDTALIRLEQLYPMPVEEIRAALAQYPNAEDFAWVQEEPANQGSW
SFVALNLLEHLDEVRLRRISRPAAAAPAVGSAKMHEVEQNALIEAALPRP
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacccagcagacttcgcaggagaacccactggcgggtttcggcccgaacgagtgg
atcgtcgaggagatgtaccagcgctacctcgccgatcccagcagcgtcgacccggcctgg
cacgacttcttcgccgactaccggcccggcgccggcaaggcccgctcggcggacggtgac
ggccaggcgaccggcaccgaatccaccccgaaggcccccgccaaggccgagccgagcgcc
aaggccgagctcgcggccaaggcggagccggccccggccaagtccacggccccggccaag
tccacagccccggcgaaggccaagccggccgccaagtccgagccggccaagacgacctcg
gcgaagtccgccccgacgaagtcggccccgaccgccaccgggccgcagaccacgccgctg
cgcggcgtcgccgcccggatcgtgcagaacatggacgcctcgctggccgtgccgaccgcg
accagcgtgcgcgcggtgccggccaagctgctggtggacaaccgcatcgtgatcaacaac
cacctcgcccgggggcgtggcggcaaggtcagcttcacccacctggtcggctacgcgctg
gtccgggcgatggtcgcgcacccggagatgaacaactccttcgccgaggtcgacggcaag
ccggcgatggtccgccccgagcacgtcaacctgggcatcgccatcgacctggccaagccc
gacggcagccggaccctggtggtgccgtccatcaagggctgcgagcagatggacttccgg
cagttctggcaggcgtacgaggacatcgtccggcgggcccgccgcaacgagctgaccatg
gacgactactccggcaccaccatctcgctgaccaaccccggcggcatcggcaccgtgcac
tcgatgccgcggctgatgcagggccagagcgcgatcatcggcgtcggcgcgatggagtac
ccggcgccgtaccagggcatgagcgaggccaccctggccgagctggcggtcagcaaggtc
atcacgctgaccagcacgtacgaccaccggatcatccagggcgcgcagtccggcgagttc
ctcaaggtcatgcacgagctgctcctcggcgagcacggctactacgaccagatcttcacc
tcgctgcgcatcccgtacgagccggtgcgctggatgcgcgacgtggcggtcgacagcgaa
ggacagatcaacaagaccgcgcgggtgcacgagctgatccactcctaccgggtccggggc
cacctgatggccgacaccgatccgctggagttcaagatccgcaagcacccggacctggac
gtcctccagcacgggctgaccctgtgggacctggaccgcacctttccggtgaacggcttc
aacggccggcagcggatgcggctgcgggagatcctcggggtgctgcgcgactcgtactgc
cgccgggtcggcatcgagtacatgcacatccaggacccggcggagcgtcgctggatccag
gagcgggtcgagcgcaagtacgagaagccgccggccgacgagcagaagcatgtgctgaac
cggctcaacgcggccgaggcgttcgagacgttcctgcagaccaagtacgtcggccagaag
cgcttctcgctggagggtggcgagtcgctgatcccgctgctcggcgaggtgctggaggcg
tccgccgagaacgacctggacgaggtcgtgatcggcatggcccaccggggtcgcctcaac
gtgctcgccaacatcgtcggcaagccgtacgagaagatcttctcggagttcgaggggcac
ctcgacccgcgctccacccagggttccggtgacgtgaaataccacctgggccagaacggc
aagttcaccactcccgacggcgaccactcggtgaaggtctcggtagtggcgaacccgtcc
cacctggaggcggtcgacccggtgctggagggcatcgtccgcgccaagcaggaccgcatc
gacctcaagctggagggctacaccgtgctgccgctggcggtgcacggcgacgccgccttc
gccggtcagggtgtggtggccgagacgctcaacctctcccagttgcgcggctaccgcacc
ggcgggacggtgcacgtggtggtcaacaaccaggtcggcttcaccaccgcgccggagtac
tcccggtccagcctctacagcaccgacgtggcccggatgatccaggcgccgatcttccac
gtcaacggcgacgaccccgaggccgtggtccgggtcgcccggctggccttcgagtaccgc
cagacgttcaacaaggacgtcgtgatcgacctggtctgctaccggcggcgcgggcacaac
gagggcgacgacccctcgatgtccaacccccagatgtacaagatcatcgactcgaagcgc
tcggtccgcaagctctacaccgaggagctgatcgggcggggtgacatcaccgtggaggac
gccgaggagctgctgcgcgactaccaggcgcagttggagcgggtcttcaaggccacccgc
gacgcggccagcaccccgcgccaggtcagccgcccggcccggcaggacgagccggagccg
caggtggagacggcgaccgaggcgtcggtgatcaaggccatcggcgaggcgcacgtcaac
ctgccggacggcttcaccccgcacaagcggatccagcagttgctcgaccggcgggcccgg
atgtccgtcgagggcaccatcgactggggcttcggcgagatcatcgccttcggtgcgctg
ctgcacgacggggtcaccgtccggctcgccggacaggactcccggcgcggcacgttcgtg
cagcggcacgcctcggtcgtggactcggagaccggcgacgactacctgccgttgcagtcg
ctgaccggcaacggtgagcggtcccgattcttcgcgcacgactcgctgctgtccgagtac
gccgcgatgggcttcgagtacggctactcggtggagaacctgaacgcgctggtctgctgg
gaggcccagttcggcgacttcgtcaacggcgcccagtcggtgatcgacgagttcatctcc
tccggcgaggtgaagtggggccagcgctccgcggtcaccctgctgctgccgcacggccac
gaggggcagggcccggaccacacctccggccgtcccgagcggttcctccagctctgcgcc
gaggacaacatgcgggtgtccatcccgaccaccccggcgaactacttccacctgctgcgt
cgccaggcgctctcgccgaagcgcaagccactggtggtgttcacgccgaagtccctgctg
cgacacaagctctgtgtctcctcggtggaggacttcacctccggcaccttctcgccggtc
ctgagcgaccaggccgcgccggctccggagcaggtcaagcgggtgctgctctgctcgggc
aaggtctactacgacctgttccaggcccggcaggagcgcagcgtcaccgacaccgcgctg
atccggctggagcagctctacccgatgccggtggaggagatccgggccgcgctcgcccag
tacccgaacgcggaggacttcgcctgggtgcaggaggagccggccaaccagggctcctgg
tcgttcgtcgcgctcaacctgctggagcacctcgacgaggtccgcctgcgtcgcatctcc
cgcccggccgccgccgccccggccgtcggctcggcgaagatgcacgaggtggagcagaac
gcgctcatcgaggcggcgctgccccgcccctga
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