Mycolicibacterium crocinum: MI149_19430
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Entry
MI149_19430 CDS
T08227
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mcro
Mycolicibacterium crocinum
Pathway
mcro00010
Glycolysis / Gluconeogenesis
mcro00020
Citrate cycle (TCA cycle)
mcro00620
Pyruvate metabolism
mcro00785
Lipoic acid metabolism
mcro01100
Metabolic pathways
mcro01110
Biosynthesis of secondary metabolites
mcro01120
Microbial metabolism in diverse environments
mcro01200
Carbon metabolism
mcro01210
2-Oxocarboxylic acid metabolism
Module
mcro_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MI149_19430 (aceE)
00020 Citrate cycle (TCA cycle)
MI149_19430 (aceE)
00620 Pyruvate metabolism
MI149_19430 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MI149_19430 (aceE)
Enzymes [BR:
mcro01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MI149_19430 (aceE)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ULN39876
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Position
3967267..3970056
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AA seq
929 aa
AA seq
DB search
MTTEFARHDLAQNSSSPNDSDRVRVIREGVASYLPDIDSEETSEWLESFDDLLARSGPAR
ARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKAHPGGGDQIFIQGHASPGIYARAF
LEGRLTADQLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGIKDTSDQHVWAFLGDGEMDEAESRGLAHVAALEALDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADKDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVADMSDSEIWNLKRGGHDYRKVYAAYRAAMEHKGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLALQDLKDFRDAIRIPVSDAQLEENPYLPPYYHPGPEAP
EIRYLIDRRRALGGFLPERRTKTKVLPLPSRDVYKALKKGSGQQQVATTMATVRTFKELL
RDKEIGKRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
EGINEAGSTASFTAVGTSYSTHNEPMIPIYIFYSMFGFQRTGDGLWAAADQMARGFVLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLARMYGEDPENVY
FYITIYNEPYAQPPEPENFDPEGLLRGMYRYRAAGEKRTNVAQILASGVAMPEALRAADL
LAERWDVAADVWSVTSWGELNRDGVEVEKELLRHPDRQARTPYVTQALADTAGPAVAVSD
WMRAVPEQIRPWVPNTYVTLGTDGFGFSDTRPAARRYFNTDAESVVVAVLEALARDGEID
PSVAIAAAKEYRIDDVMAAEVSYVDTGSA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgagttcgcgcgccacgacctggctcaaaactcaagcagcccaaatgattcc
gatcgagtacgggtgatccgcgaaggcgtcgcgtcatatctgcccgatatcgactccgag
gagacctcggaatggctggagtcgttcgacgacctgctggcccgttcgggcccggcccgg
gcgcgctatctgatgctgcggctgctcgagcgcgccggtgagcagcgcgttgcgatcccg
gcgttgacctccaccgactacgtcaacaccattcccaccgagctggagccgtggttcccc
ggcgacgaggacgtcgagcgccgctaccgcgcttggattcggtggaacgccgcgatcatg
gtgcaccgcgcgcagcggccgggcgtcggcgtcggcgggcacatctccacctatgcctcg
tcggccgcgctgtacgaggtcggcttcaaccacttcttccgcggcaaagcccacccgggc
ggcggcgaccagatcttcatccagggccacgcctcccccggcatctacgcgcgcgccttc
ctcgaaggccggctcaccgccgaccagctcgacggcttccgccaggaacacagccacccc
ggcggcgggctgccgtcctacccacacccgcggctgatgccggacttctgggagttcccg
accgtgtcgatgggcctgggcccgatgaacgcgatctatcaggcgcggttcaaccactac
ctgcacgaccgcggcatcaaggacacctccgatcagcacgtgtgggcgttcctcggtgac
ggcgagatggacgaggccgagagccgcggcctggcccacgtcgccgcgctggaagcgctc
gacaacctgacgttcgtcatcaactgcaacctgcagcgcctcgacgggccggtgcgcggc
aacggcaagatcatccaggagctggagtccttcttccgcggtgcgggctggaacgtcatc
aaggtggtgtggggccgcgaatgggacgccctgctgcacgccgataaggacggcgcgctg
gtgaacctgatgaacaccacgcccgacggtgattaccagacctataaggccaacgacggc
gcgtatgtgcgcgaccacttcttcggccgtgacccgcggaccaaggctctggtggccgat
atgagcgacagcgagatctggaacctcaagcgcggcggccacgactaccgcaaggtctat
gccgcctaccgcgcggcgatggagcacaagggccagccgacggtcatccttgccaagacg
atcaagggttactcgctgggtgcccacttccagggccgcaacgccacccaccagatgaaa
aagcttgcgctgcaagacctcaaagacttccgcgatgccatccggatcccggtgtcggac
gcgcagctcgaggagaacccctacctgccgccgtactaccaccccgggccggaggcgccg
gagatccgctacctcatcgaccgccgccgggccctgggcggcttcctgccggagcgccgt
accaagaccaaggtccttcccctgccgtcgcgcgacgtgtacaaggcgctgaagaagggg
tccggccagcaacaggtggccaccacgatggccactgtgcgcacgttcaaagagctgttg
cgcgacaaggagatcggcaagcggatcgtgccgatcattcccgacgaggcgcgcaccttc
ggcatggactcgtggttcccgagcctgaagatctacaaccgcaacggccagctgtacacc
gccgtcgacgccgaattgatgttggcgtacaaggaaagtgaagtcggccagatcctgcac
gagggcatcaacgaggccggctcgacggcgtcgttcaccgcggtgggcacgtcctactcc
acgcacaacgagccgatgatcccgatctacatcttctattcgatgttcgggttccagcgc
accggcgacggattgtgggcggccgccgatcagatggcccgcggcttcgtgctcggcgcg
acagccggtcgcaccacgctgaccggcgagggtctgcagcacgcggacgggcactcgctg
ctgctcgctgcgaccaaccctgctgtggtggcttacgacccggcgttcgcctacgagatc
gcctacatcgtggaaagcggcctggcgcggatgtacggcgaggacccggagaacgtctac
ttctacatcaccatctacaacgagccctacgcccagccgccggagccggagaacttcgac
cccgaaggcctgctgcgcggcatgtatcgctaccgggcggccggggagaagcgcacgaac
gtcgcgcagatcctggcctcgggcgtggcgatgcccgaggcgctgcgcgccgccgacctg
ctggccgagcgctgggacgtcgccgccgacgtctggtcggtgaccagctggggtgagctc
aaccgcgacggcgtcgaggtggagaaggagctgctgcgccacccggaccggcaggcccgg
acgccgtacgtgacgcaggcgctggccgataccgcaggcccggccgtcgccgtgtcggac
tggatgcgcgcggtgcccgagcagatccgcccgtgggtgcccaacacctacgtcacgctg
ggcaccgacgggttcggtttctccgacacccggcccgcggcccggcgctacttcaacacc
gacgccgagtcggtggtggtggcggtgctggaggcgctggcccgcgacggcgagatcgac
ccgtcggtggcgatcgcggcagccaaggagtaccggatcgacgacgtgatggccgccgag
gtctcctacgtcgacaccggcagcgcctag
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