Mycolicibacterium crocinum: MI149_22970
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Entry
MI149_22970 CDS
T08227
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mcro
Mycolicibacterium crocinum
Pathway
mcro00020
Citrate cycle (TCA cycle)
mcro00630
Glyoxylate and dicarboxylate metabolism
mcro00785
Lipoic acid metabolism
mcro01100
Metabolic pathways
mcro01110
Biosynthesis of secondary metabolites
mcro01120
Microbial metabolism in diverse environments
mcro01200
Carbon metabolism
mcro01210
2-Oxocarboxylic acid metabolism
Module
mcro_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mcro_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mcro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MI149_22970
00630 Glyoxylate and dicarboxylate metabolism
MI149_22970
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MI149_22970
Enzymes [BR:
mcro01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
MI149_22970
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
MI149_22970
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
MI149_22970
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
MI149_22970
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Vert_IL3-reg_TF
Motif
Other DBs
NCBI-ProteinID:
ULN40494
LinkDB
All DBs
Position
4722819..4726553
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AA seq
1244 aa
AA seq
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MSSTSSPFGQNEWLVEEMYRKFREDPSSVDSSWHEFLVDYNPEPTSDSTASGNGQPAAKT
AAPVSPPEPAPAPPPAKSAPAKSAPAGNGASSSAAPVKDTAKPPAKEPAPKAAAASSSSD
GGDETQVLRGAAAAVVRNMNTSLEIPTATSVRAIPAKLMIDNRIVVNNHLKRTRGGKVSF
THLLGYAIVQAVKKFPNMNRHYAEIDGKPNAVTPAHTNLGLAIDLQGKDGKRSLVVAAIK
NCETMRFGQFIAAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMSGQGAI
VGAGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHELLLSDD
FFDEIFFELGIPYEPVRWRTDNPDSIVDKNARVIELIAAYRNRGHLMADIDPLRLDKTRF
RSHPDLDVNTHGLTLWDLDRVFKVDGFAGKEFKKLRDVLGLLRDAYCRHIGVEYTHILEP
EQQKWLQERIEVKHEGPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVIPM
MDAAIDQAAEHALDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVK
YHLGASGNYIQMFGDNDIEVSLTANPSHLEAVDPVMEGIVRAKQDLLDKGDGDDGFTVMP
LMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHIIVNNQIGFTTSPQDSRSSEYCTDVA
KMVGAPIFHVNGDDPEACVWVARLAVDFRQKFKKDVIIDMLCYRRRGHNEGDDPSMTQPY
MYDVIDTKRGVRKTYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRDLEKHEVEPSE
SVEEDQMIPRGMTTAVDKSLLARIGDAHLAFPENFNVHPRVKPVLEKRREMAYEGKVDWA
FAELLALGTFLAEGKLIRLSGQDTRRGTFTQRHSVIIDRKTGAEFTPLDLLTVNPDGTPT
GGKLMVYDSALSEYAAVGFEYGYSVGNQDALVMWEAQFGDFVNGAQSIIDEFISSGEAKW
GQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIALPSTPANYFHLLRRHGLDG
VHRPLIVFTPKSMLRNKAAVSDIRDFTEQKFRSIMEEPTYTDGDGDRNKVTRILLTSGKI
YYELAARKDKDKREDVAIVRVEQLAPLPKRRLSNTLDSYPNAKEFFWVQEEPANQGAWPT
FGLTLPEKLTGIKRISRRAMSAPSSGSSKVHAVEQQEIIDEAFG
NT seq
3735 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagtactagttcaccattcggacagaacgaatggctggtcgaggagatgtaccgc
aagttccgcgaggacccctcctcggtcgactcgagttggcatgagttccttgtcgactac
aacccggagccgacgagcgactcgaccgccagcggtaacggccaaccggccgcgaagacc
gccgctccggtgtcaccgccggaacccgcaccggctcccccgccggccaagtccgctccc
gccaagtccgctcccgcgggcaatggcgcgtcgagctcggccgctccggtcaaagacacc
gccaagcctccggccaaggagccggcacccaaggccgcagcagcgtcgtcgtcctccgat
ggcggcgacgagacgcaggtgttgcgcggcgcggcagccgccgtcgtccgcaacatgaac
acctcgctggagatcccgaccgcgaccagcgtgcgggccatcccggcgaagctgatgatc
gacaaccgcatcgtcgtcaacaaccacctcaagcgcactcgcggcggcaaggtgtccttc
acccacctgctcggctacgcgatcgtgcaggcggtgaagaagttcccgaacatgaaccgg
cactacgccgagatcgacggcaagcccaacgccgtcacccccgcgcacaccaatctgggt
ctcgcgatcgacctgcagggcaaggacggtaagcgctctctggtggtcgccgcgatcaaa
aactgcgagaccatgcggttcggccagttcatcgccgcctacgaggacatcgtgcggcgc
gcccgcgacggcaagctcaccgccgaggatttcgccggtgtgacgatctcgctgaccaac
cccggcaccatcggcaccgtgcactcggtgccccggttgatgtccggccagggtgcgatt
gtcggcgccggcgcgatggagtatccggcggagttccagggggcgagcgaggagcgcatc
gccgaactcggcatcggcaagctgatcacgctgacgtcgacctacgaccaccgcatcatt
cagggcgcggagtccggcgacttcctgcggaccatccacgaactgctgctgtcggacgat
ttcttcgacgagatcttcttcgagctgggcatcccttacgagccggtccgttggcgcacc
gacaaccccgattcgatcgtcgacaagaacgctcgcgtcatcgaactcattgcggcctac
cgcaaccgcgggcatctgatggccgacatcgacccgctgcgcttggacaagacccgcttc
cgcagccaccccgaccttgacgtgaacacccacggcctgacgctgtgggatctcgaccgg
gtgttcaaggtcgacggcttcgcgggcaaggagttcaagaagctgcgcgacgtcctcggg
ctgctgcgcgacgcctactgccgccacatcggtgtggagtacacccacatcctggagccc
gagcagcagaagtggctgcaggagcgcatcgaggtcaagcacgagggtccgacggtcgcc
cagcaaaagtacatcctgtcgaagctgaacgccgccgaagccttcgagaccttcctgcag
acgaaatatgttgggcagaagcgcttctcgctggaaggtgcggaaaccgtcatcccgatg
atggacgccgcgatcgaccaggccgccgagcacgcgctcgacgaggtcgtgatcggcatg
ccgcaccgcggccggctcaacgtgctggccaacatcgtcggcaagccctactcgcagatc
ttcagcgagttcgagggcaacctgaacccgtcgcaggcgcacggttccggtgacgtcaag
taccacctcggcgccagcggcaactacatccagatgttcggcgacaacgacatcgaggtc
tcgctgaccgccaacccgtcgcacctggaagccgtagatccggtgatggaaggcatcgtt
cgggccaagcaggatctgctcgacaagggcgacggcgacgacggcttcaccgtcatgccg
ctgatgctgcacggcgatgcggccttcgccggtcagggcgtggtggccgagaccctcaac
cttgcgctgctgcgtgggtaccgcaccggcggcacgatccacatcatcgtcaacaaccag
atcggcttcaccacctcgccgcaggactcacgcagctcggagtactgcaccgacgtcgca
aagatggtgggagcgcccatcttccacgtcaacggtgacgacccggaggcctgcgtctgg
gtggcgcggctcgcggtggacttccggcagaagttcaagaaggacgtcatcatcgacatg
ctgtgctaccgccgacgcgggcacaacgaaggtgacgacccgtcgatgacccagccgtac
atgtacgacgtcatcgacaccaagcgcggtgtccgcaagacctacaccgaagccctgatc
ggccgcggcgacatctcgatgaaagaggccgaggacgcgctgcgcgactaccagggtcag
ctggagcgggtgttcaacgaggtccgcgatctcgagaaacacgaggtcgaaccgagcgaa
tcggtcgaggaagaccagatgatcccgcgcggcatgaccaccgcggtggacaagtcgctg
ctggcccgtatcggtgacgcgcatctggcgttcccggagaatttcaacgtgcacccccgc
gtcaagccggtgctggagaagcgccgcgagatggcgtacgagggcaaggtcgactgggcg
ttcgccgaattgctggcgctcggaacatttttggccgaaggcaagctgatccgcttgtcg
ggtcaggacactcggcgcggcacgttcactcagcggcactcggtgatcatcgaccgcaag
accggcgcggagttcaccccgctggacctgctgaccgtcaacccggacggcacaccgacc
ggcggcaagctgatggtgtacgactcggcgctgtcggagtacgcggcggtcggcttcgaa
tacggctattccgtgggcaatcaggacgcactcgtcatgtgggaggcgcagttcggcgat
ttcgtcaacggtgcgcagtcgatcatcgacgagttcatcagctccggcgaagccaagtgg
ggtcagctctccgatgtggtgctgctgctcccccacggtcatgagggccaaggccccgac
cacacctcgggtcgcatcgagcggttcctccagctgtgggccgagggttcgatgacgatc
gcgctgccgtcaaccccggcgaactacttccatctgctgcgcaggcacggcctcgacgga
gtgcaccgtccgctgatcgtgttcacgccgaagtcgatgctgcgtaacaaggctgccgtc
agcgacatccgggacttcaccgagcagaagttccgctcgatcatggaggagccgacctac
accgacggcgacggcgaccgcaacaaggtcacccgaatcctgttgaccagcggcaagatc
tactacgagctggcggcccgcaaggacaaagacaagcgcgaggacgtcgcgatcgtccgc
gtcgagcagctggcgccgctgcccaagcggcgactgagcaacaccttggattcgtacccg
aatgccaaggagttcttctgggtccaggaggagccggccaaccagggtgcgtggccgacg
ttcggcttgacgttgccggagaagctgaccgggatcaagcggatctcgcggcgcgcaatg
tcggcgccgtcgtccggctcgtcgaaggtgcacgctgtcgagcagcaggagatcatcgac
gaggcgttcggctag
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