Microbacterium aurantiacum: A8L33_10645
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Entry
A8L33_10645 CDS
T04340
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mcw
Microbacterium aurantiacum
Pathway
mcw00010
Glycolysis / Gluconeogenesis
mcw00020
Citrate cycle (TCA cycle)
mcw00620
Pyruvate metabolism
mcw00785
Lipoic acid metabolism
mcw01100
Metabolic pathways
mcw01110
Biosynthesis of secondary metabolites
mcw01120
Microbial metabolism in diverse environments
mcw01200
Carbon metabolism
mcw01210
2-Oxocarboxylic acid metabolism
Module
mcw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
A8L33_10645
00020 Citrate cycle (TCA cycle)
A8L33_10645
00620 Pyruvate metabolism
A8L33_10645
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
A8L33_10645
Enzymes [BR:
mcw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
A8L33_10645
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ANG85783
UniProt:
A0A0M9VKG5
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Position
2248729..2251458
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AA seq
909 aa
AA seq
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MTVNDQDPYSQDPLDSDPDETSEWQESLHQLVQAKGPGRGREIMLSLLQASHDLQLNVPQ
VPTTDYINTIAPENEPEFPGDEELERRYRRWIRWNAAITVHRAQRPGIGVGGHISTYASS
ASLYEVGFNHFFRGLDDPSGGDQIFIQGHASPGIYARSFLEGRLSEQQLDGFRQEKSKAP
EGIPSYPHPRLMPEYWQFPTVSMGLGPINAIYQAMSNKYLTNRGIKDLSNSHVWAFLGDG
EMDEVESRGQLQVAANEGLDNLTFVINANLQRLDGPVRGNGKIIQELESFFRGAGWNVIK
VVWGSGWDELLSKDTDGALVRLMNTTPDGDFQTYRAEDGGFIREHFFGRDERTAALVKDW
SDDDIWGRLRRGGLDYRKVYAAYKAAAEHKGQPTVIIAKTIKGYGLGHHFEGRNATHQMK
KMTLEDLKHFRDSMRIPISDAQLEENPYLPPYYNPGAEDETIQYMQERRRSLGGFLPERR
SHHVGLTLPDESAYALPKKGSGTQEIATTMAFVRLLKDLLKAKDFGHRIVPIIPDEARTF
GMDAYFPTAKIYNPHGQNYTSVDRSLLLAYKESPQGQILHVGINEAGALAAFTAAGTSYS
THGEPLIPVYVFYSMFGFQRTGDAQWAAGDQMARGFIIGATAGRTTLTGEGLQHADGHSH
LLASTNPATVSYDPAYGYEIAHIVRSGIERMYGGEHPDPNVMYYITVYNEPLVQPAEPEG
VDVDGIVRGMHRISSPEGEGPRAQILASGVGVPWAMEAQQLLRDDWGVQADVWSVTSWTE
LRRDGLAADEHNFLHPEDEARTAFVTEKLKDAEGPVVAVSDFMHAVQDQIRPWVPQQFVT
LGADGFGFSDTRAAARRYFKIDGPSVVVRTLQALAAEGKVDRSLSAQAIEKYRLHDVSAG
TSGNAGGES
NT seq
2730 nt
NT seq
+upstream
nt +downstream
nt
gtgactgtcaacgatcaggatccgtactcgcaggacccgctggacagcgatcccgacgag
acgtccgagtggcaggagtcactccaccagctcgtccaggccaaagggccggggcgaggg
cgcgagatcatgctgagcctcctgcaggcctcgcatgaccttcagctcaacgtgccgcag
gtgcccaccaccgactacatcaacaccatcgctccggagaacgagccggagttccccggc
gacgaggagctcgagcgtcgctaccgacgctggatccggtggaacgccgccatcaccgtg
caccgcgcgcagcgccccggcatcggcgtcggcgggcacatctccacctacgcgtcctcg
gcgtcgctctacgaagtcggcttcaaccacttcttccgcggcctcgacgacccgagcggc
ggggaccagatcttcatccaggggcacgcctcccccggcatctatgcccgctcgttcctc
gaaggccgcctcagcgagcagcagctcgacggcttccgacaggagaagtcgaaggcaccg
gagggaatcccctcctacccgcaccctcgcctcatgccggagtactggcagttcccgacg
gtgtcgatgggtctcggtccgatcaacgccatctaccaggcgatgtcgaacaagtacctc
accaaccgcggcatcaaggacctctcgaactcgcacgtctgggccttcctcggcgacggc
gagatggacgaggtcgagagccgcggacaactgcaggtcgccgccaacgagggcctggac
aacctgaccttcgtcatcaacgccaacctgcagcgtctcgacggccccgtccgcggaaac
ggcaaaatcatccaggagctggagagcttcttccgcggcgccggttggaacgtcatcaag
gtcgtgtggggctccggctgggacgagctgctgtccaaggacaccgacggcgcgctggtc
cgcctgatgaacaccacgccggacggcgacttccagacctaccgcgcggaggacggcgga
ttcatccgcgagcacttcttcgggcgcgacgagcggaccgccgccctcgtcaaggactgg
tcggacgacgacatctggggtcgcctgcgccgcggcggactggactaccgcaaggtgtac
gccgcgtacaaggccgccgccgagcacaagggtcagccgaccgtcatcatcgccaagacc
atcaagggctacgggctcggtcaccacttcgaggggcgcaacgcgacgcaccagatgaag
aagatgacgctcgaagacctcaagcacttccgcgactcgatgcgcatcccgatctcggac
gcgcagctcgaagagaacccgtacctcccgccgtactacaaccccggcgccgaagacgag
acgatccagtacatgcaggagcgtcgtcgctcgctcggcgggttcctccccgagcgtcgc
tcgcaccacgtggggctcaccctccccgacgaaagcgcctacgcgctcccgaagaagggt
tcgggcacacaggagatcgccaccacgatggcgttcgtccggctgctcaaggacctgctg
aaggccaaagacttcggccaccgcatcgtgccgatcattccggacgaggcacgcaccttc
gggatggacgcctacttcccgaccgcgaagatctacaacccgcacgggcagaactacacc
tcggtggaccggtcgctcctgctggcgtacaaggagagcccgcaggggcagatcctgcac
gtcggcatcaacgaggccggcgcactcgcggcgttcaccgcggcgggcacgtcgtactcc
acccacggagaaccgctcatccccgtctacgtcttctactcgatgttcggcttccagcgg
accggcgacgcgcagtgggccgccggtgaccagatggcccgcgggttcatcatcggcgcc
accgccggacgcacgacgctgacgggcgaaggtctccagcacgccgacgggcactcgcac
ctcctggcctcgaccaacccggcgacggtgtcctacgaccccgcctacggctacgagatc
gcccacatcgtgcgctccggcatcgagcgcatgtacggcggcgagcacccggaccccaac
gtgatgtactacatcaccgtctacaacgagccgctggtccagcccgccgagcccgagggg
gtcgacgtcgacggcatcgtccgcggcatgcaccgcatctcctcgccggagggagagggt
ccgcgcgcgcagatcctcgcgtcgggcgtgggtgtgccgtgggcgatggaggcgcagcag
ctgctacgcgacgactggggtgtccaggcggacgtctggtccgtgacgtcctggacggag
cttcgccgcgacggtctcgccgcggacgagcacaacttcctccaccccgaggacgaagcg
cggacggcgttcgtcaccgagaagctgaaggatgccgaaggtcccgtggtcgccgtcagc
gacttcatgcacgccgtccaggatcagatccggccctgggttcctcagcagttcgtgacc
ctcggggcggacggcttcggcttctccgacacgcgtgccgcggcacggcgctacttcaag
atcgacggcccgtccgtcgtggtccgcaccctgcaggcgctggccgccgagggcaaggtc
gaccggagcctgtccgctcaggcgatcgagaagtaccgcctgcacgacgtcagcgccgga
acgagcggcaacgcgggcggcgagagctga
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