KEGG   MODULE: M00573
Entry
M00573            Pathway   Module                                 
Name
Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
Definition
K16593 K00652 K19563 K01935 K01012
Diagram
M00573  Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
M00573

Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00780  Biotin metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Orthology
K16593  
bioI; pimeloyl-[acyl-carrier protein] synthase [EC:1.14.14.46] [RN:R10123]
K00652  
bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] [RN:R10124]
K19563  
bioA; lysine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.105] [RN:R10699]
K01935  
bioD; dethiobiotin synthetase [EC:6.3.3.3] [RN:R03182]
K01012  
bioB; biotin synthetase [EC:2.8.1.6] [RN:R01078]
Complete
bsu  Bacillus subtilis subsp. subtilis 168
bsr  Bacillus subtilis subsp. subtilis RO-NN-1
bsl  Bacillus subtilis subsp. subtilis BSP1
bsh  Bacillus subtilis subsp. subtilis 6051-HGW
bsy  Bacillus subtilis subsp. subtilis BAB-1
bsut  Bacillus subtilis subsp. subtilis AG1839
bsul  Bacillus subtilis subsp. subtilis JH642
bsus  Bacillus subtilis subsp. subtilis OH 131.1
bso  Bacillus subtilis subsp. natto BEST195
bsn  Bacillus subtilis BSn5
bsq  Bacillus subtilis QB928
bsx  Bacillus subtilis XF-1
bsp  Bacillus subtilis PY79
bss  Bacillus subtilis subsp. spizizenii W23
bst  Bacillus spizizenii TU-B-10
bit  Bacillus spizizenii T30
bli  Bacillus licheniformis ATCC 14580
bld  Bacillus licheniformis DSM 13 = ATCC 14580
blh  Bacillus paralicheniformis
bay  Bacillus velezensis FZB42
baq  Bacillus velezensis CAU B946
bya  Bacillus velezensis YAU B9601-Y2
bqy  Bacillus velezensis YAU B9601-Y2
bamp  Bacillus velezensis AS43.3
baml  Bacillus velezensis UCMB5036
bama  Bacillus velezensis UCMB5033
bamn  Bacillus velezensis UCMB5113
bamb  Bacillus velezensis NAU-B3
bamt  Bacillus velezensis TrigoCor1448
bamy  Bacillus velezensis SQR9
bmp  Bacillus velezensis JS25R
bao  Bacillus amyloliquefaciens DSM 7
baz  Bacillus amyloliquefaciens TA208
bql  Bacillus amyloliquefaciens LL3
bxh  Bacillus amyloliquefaciens XH7
bami  Bacillus amyloliquefaciens IT-45
bamc  Bacillus amyloliquefaciens CC178
bamf  Bacillus amyloliquefaciens LFB112
bsia  Bacillus siamensis
bae  Bacillus atrophaeus
bvm  Bacillus vallismortis
bson  Bacillus sonorensis
bht  Bacillus halotolerans
bmoj  Bacillus mojavensis
biq  Bacillus inaquosorum
bstr  Bacillus stercoris
bgy  Bacillus glycinifermentans
bcab  Bacillus cabrialesii
bry  Bacillus rugosus
bacp  Bacillus sp. Pc3
bacb  Bacillus sp. BH072
bacy  Bacillus sp. YP1
bacl  Bacillus sp. BS34A
balm  Bacillus sp. LM 4-2
bacs  Bacillus sp. SDLI1
bacq  Bacillus sp. Y1
baqu  Bacillus aquiflavi
bafc  Bacillus sp. FCW2
bkn  Bacillus kandeliae
beo  Priestia filamentosa
bgi  Alkalicoccobacillus gibsonii
bpf  Alkalihalophilus pseudofirmus
msem  Metabacillus sediminilitoris
ross  Rossellomorea sp. y25
alkl  Alkalihalobacillus sp. LMS39
dom  Domibacillus sp. DTU_2020_1001157_1_SI_ALB_TIR_016
 » show all
Reaction
R10123  
R10124  
R10699  
R03182  
R01078  
Compound
C20683  Long-chain acyl-[acyl-carrier protein]
C19845  Pimeloyl-[acyl-carrier protein]
C01092  8-Amino-7-oxononanoate
C01037  7,8-Diaminononanoate
C01909  Dethiobiotin
C00120  Biotin
Reference
PMID:21437340
  Authors
Lin S, Cronan JE
  Title
Closing in on complete pathways of biotin biosynthesis.
  Journal
Mol Biosyst 7:1811-21 (2011)
DOI:10.1039/c1mb05022b
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