KEGG   Mycolicibacterium diernhoferi: K0O62_14350
Entry
K0O62_14350       CDS       T07506                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mdf  Mycolicibacterium diernhoferi
Pathway
mdf00270  Cysteine and methionine metabolism
mdf00450  Selenocompound metabolism
mdf00670  One carbon pool by folate
mdf01100  Metabolic pathways
mdf01110  Biosynthesis of secondary metabolites
mdf01230  Biosynthesis of amino acids
mdf04980  Cobalamin transport and metabolism
mdf04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:mdf00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    K0O62_14350 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    K0O62_14350 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    K0O62_14350 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    K0O62_14350 (metH)
   04980 Cobalamin transport and metabolism
    K0O62_14350 (metH)
Enzymes [BR:mdf01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     K0O62_14350 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: QYL20304
LinkDB
Position
3045122..3048868
AA seq 1248 aa
MHVTGLEPNIRPDCTDELTAALQQRIVVIDGAMGTAIQRDRPDEDGYRGDRFTEWPTALQ
GNNDLLNLTQPQIIEGIHREYLEAGADILETNTFNANAVSLSDYDMADLSYELNYVGAAL
ARKAADEYSTPDKPRYVAGAIGPTTRTASISPDVNDPGARNVSYDQLVAAYLEAANGLVD
GGSDLIIIETIFDSLNAKAAVFAVETLFEQRGRRWPVIISGTITDASGRTLSGQVTEAFW
NAIRHARPIAVGLNCALGAPEMRPYIAEMARIADTYVSCYPNAGLPNAFGEYEESPQRQA
SYIAEFAEAGLVNLVGGCCGTAPPHIAEIAKVVDGKAPRELPQIPVATRLSGLEPLNISD
SSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGVAA
MDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIVNSISLKEGEEKFIREARL
CRKYGAAVVVMAFDEQGQADNLERRKEICGRAYRILTEEVGFPAEDIIFDPNCFALATGI
EEHATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGL
DMGIVNAGALVPYDSIDPELRERIEDVVLNRRADAAERLLEIAERFNSKNSGEGDERAAA
EWRSLPVRERITHALVKGIDAHVDADTEELRAEIDAAGGRPIEVIEGPLMDGMNVVGDLF
GAGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEASGAAAGKDTNGTIIMATVKGDVHDIG
KNIVGVVLQCNNFEVIDLGVMVPAQKILDAAREHDADIIGLSGLITPSLDEMVNFAVEME
REGLQIPLLIGGATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDRQRPALLEA
TAKDYAALRERHAQKNERPMLTLEKARANRTPIEWDGYTPPVPAQGVGVREFIDYDVAEL
REYIDWQPFFNAWEMKGRFPDILNNPVSGEAARKLYDDAQEMLDTLIKEKWLRANGVIGF
FCANAVGDDIEVYTDESRTEVLTTLHNLRQQGEHRAGIPNRSLGDFVAPRETGLRDYVGA
FAVTAGLGSQDKITEFKADHDDYNAILLESLADRLAEAFAERMHQRVRQEFWGYQPDEQL
DNAALIGEKYVGIRPAPGYPACPEHTEKATLFELMDVTERTGIELTESMAMWPGAAVSGW
YFSHPQSQYFVVGRMAQDQIADYARRKGWTLAEAERWLAPNLGYNPED
NT seq 3747 nt   +upstreamnt  +downstreamnt
gtgcacgtgacaggccttgagccgaacatccgcccggactgcaccgacgagctgaccgcc
gctctgcagcagcgcatcgtggtgatcgacggcgccatgggcacggcgatccagcgcgac
cgccccgacgaggacggctaccgcggtgaccggttcacggagtggccgacggcgctgcag
ggcaacaacgacctgctcaacctgacgcagccgcagatcatcgagggcatccaccgcgag
tacctggaagcgggcgcggacatcctggagaccaacacgttcaacgcgaacgcggtctcg
ctgtcggactacgacatggccgacctgagctacgagctgaactacgtgggcgccgccctc
gcccgcaaggccgccgacgagtacagcaccccggacaagccccgctacgtcgccggcgcc
atcgggccgacgacccgcaccgcgtccatctcaccggacgtcaatgacccgggcgcccgc
aacgtctcctacgaccagctcgtggccgcctacttggaggctgccaacggcctggtcgac
ggcggctccgatctgatcatcatcgagaccatcttcgactcgctgaacgccaaggcggcg
gtcttcgccgtcgagacgctgttcgagcagcgcggccggcgctggccggtgatcatctcc
ggcaccatcaccgacgcgtccgggcgcacgctgtccggccaggtcaccgaggcgttctgg
aacgcgatccggcacgcgagaccgatcgcggtcggcctcaactgcgccctcggcgcaccg
gagatgcggccctacatcgccgagatggcacgcatcgcggacacctacgtctcctgctac
ccgaacgccggcctgcccaacgccttcggtgagtacgaagagtctccgcagcgccaggcc
tcctacatcgccgagttcgccgaggccggcctggtcaacctggtcggcgggtgctgtggc
accgcgccgccgcacatcgccgagatcgccaaggtcgtcgacggcaaggcgcctcgcgaa
ctgccgcagatcccggtggccacccggctgtccggcctggagccgctgaacatctccgac
agctcgctgttcgtgaacatcggggagcgcaccaacatcaccggctcggcccggttccgc
aacctgatcaaggccgaggattacgacaccgcgttgtcggtggcgctgcagcaggtcgag
gtcggtgcgcaggtcatcgacatcaacatggacgagggcatgatcgacggcgtcgccgcg
atggaccggttcaccaagctgatcgccgccgaaccggacatcagccgcgtcccggtgatg
atcgactcctcgaagtgggaggtcatcgaggccggcctgaagaacgtgcagggcaagccg
atcgtcaactcgatctccctgaaggagggcgaggagaagttcatccgcgaggcccggctg
tgccgcaagtacggcgcggccgtcgtcgtgatggccttcgacgaacagggccaggccgac
aacctggagcgccgcaaggagatctgcgggcgcgcctaccggatcctgaccgaagaagtc
ggcttcccggccgaggacatcatcttcgacccgaactgcttcgctctggccaccggtatc
gaggagcacgccacctacgggatcgacttcatcgaggcgtgcgcctggatcaaggagaac
ctgcccggggtgcacatctccggcggcatctcgaacgtgtcgttctcgttccgcggcaac
aacccggtccgcgaggccatccacgcggtgttcctgttccacgccatcaaggccggcctg
gacatgggcatcgtcaatgccggtgcgctggtgccgtacgactcgatcgaccccgagctg
cgcgagcgcatcgaggacgtggtgctcaaccgccgcgcggatgccgccgagcggctgctg
gagatcgcggagcggttcaacagcaagaactcgggagagggtgacgagcgagctgccgcc
gaatggcgcagcttgccggttcgcgaacgcatcacgcacgccctggtcaagggcatcgac
gcgcacgtcgacgccgacaccgaggaactgcgggccgagatcgatgccgccggcgggcgg
ccgatcgaggtgatcgagggcccgctgatggacgggatgaacgtcgtcggcgacctcttc
ggtgcgggcaagatgttcctgccccaggtggtgaagtcggcccgggtgatgaagaaggcc
gtcgcctatctgctgccgttcatcgaggccgagaaggaggcctccggcgcggccgccggt
aaggacaccaacggcaccatcatcatggcgaccgtcaagggcgatgtccacgacatcggc
aagaacatcgtcggagtcgtgctgcagtgcaacaacttcgaggtgatcgacctcggggtg
atggtgcccgcgcagaagatactcgacgcggccagggagcacgacgcggacatcatcggg
ttgtccggtctgattaccccgtcgctggacgagatggtgaacttcgccgtcgagatggag
cgcgaaggactgcagatcccgctgctgatcggcggcgcgaccacctcgcgcgcccacacc
gcggtgaaggtggcgccgcgccgcagcggcccggtggtctgggtcaaggacgcgtcccgc
tcggtgccggtcgccgcggcgctgctcgacgacaggcagcggcccgcgctgctggaggcc
accgcgaaggactacgcggccctgcgcgaacggcacgcccagaagaacgagcggccgatg
ctgaccctggagaaggcccgggcgaaccgcaccccgatcgagtgggacggctacacgcca
ccggtgcccgcccagggtgtcggggtccgcgagttcatcgactacgacgtggccgagttg
cgcgagtacatcgactggcagccgttcttcaacgcctgggagatgaagggccggttcccg
gacatcctgaacaaccccgtgtcgggggaggccgcccgcaagctgtacgacgacgcccag
gagatgctcgacaccctgatcaaggagaagtggctgagggccaacggggtgatcgggttc
ttctgcgccaacgccgtcggcgacgacatcgaggtctacaccgacgagagccggaccgag
gtgctcaccacgctgcacaacctgcgccagcagggggagcaccgcgccggcatcccgaac
cggtccctgggcgacttcgtcgcccccagagaaacgggcctgcgggattacgtcggcgcg
ttcgccgtcaccgcggggctgggcagccaggacaagatcacggagttcaaggccgaccac
gacgactacaacgcgatcctgctggagtcgctggccgaccggctggccgaggcgttcgcc
gaacggatgcaccagcgggtacgccaggagttctggggttaccagcccgacgagcaactg
gacaacgcggcgctgatcggggagaagtacgtcgggatccgcccggcgcccggctacccg
gcctgccccgaacacaccgagaaggccaccctgttcgagttgatggacgtcaccgagcgg
accggcatcgagctgaccgaatcgatggcgatgtggcccggggccgcggtcagcggctgg
tacttctcgcacccgcagtcgcagtacttcgtggtgggccggatggctcaggatcagatc
gccgactacgcccggcgcaagggctggaccctggccgaagccgagcgctggctggcaccc
aatctcggctacaacccggaggactga

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