Mycolicibacterium diernhoferi: K0O62_14350
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Entry
K0O62_14350 CDS
T07506
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mdf
Mycolicibacterium diernhoferi
Pathway
mdf00270
Cysteine and methionine metabolism
mdf00450
Selenocompound metabolism
mdf00670
One carbon pool by folate
mdf01100
Metabolic pathways
mdf01110
Biosynthesis of secondary metabolites
mdf01230
Biosynthesis of amino acids
mdf04980
Cobalamin transport and metabolism
mdf04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mdf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
K0O62_14350 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
K0O62_14350 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
K0O62_14350 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
K0O62_14350 (metH)
04980 Cobalamin transport and metabolism
K0O62_14350 (metH)
Enzymes [BR:
mdf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
K0O62_14350 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
CdhD
Motif
Other DBs
NCBI-ProteinID:
QYL20304
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Position
3045122..3048868
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AA seq
1248 aa
AA seq
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MHVTGLEPNIRPDCTDELTAALQQRIVVIDGAMGTAIQRDRPDEDGYRGDRFTEWPTALQ
GNNDLLNLTQPQIIEGIHREYLEAGADILETNTFNANAVSLSDYDMADLSYELNYVGAAL
ARKAADEYSTPDKPRYVAGAIGPTTRTASISPDVNDPGARNVSYDQLVAAYLEAANGLVD
GGSDLIIIETIFDSLNAKAAVFAVETLFEQRGRRWPVIISGTITDASGRTLSGQVTEAFW
NAIRHARPIAVGLNCALGAPEMRPYIAEMARIADTYVSCYPNAGLPNAFGEYEESPQRQA
SYIAEFAEAGLVNLVGGCCGTAPPHIAEIAKVVDGKAPRELPQIPVATRLSGLEPLNISD
SSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGVAA
MDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIVNSISLKEGEEKFIREARL
CRKYGAAVVVMAFDEQGQADNLERRKEICGRAYRILTEEVGFPAEDIIFDPNCFALATGI
EEHATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGL
DMGIVNAGALVPYDSIDPELRERIEDVVLNRRADAAERLLEIAERFNSKNSGEGDERAAA
EWRSLPVRERITHALVKGIDAHVDADTEELRAEIDAAGGRPIEVIEGPLMDGMNVVGDLF
GAGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEASGAAAGKDTNGTIIMATVKGDVHDIG
KNIVGVVLQCNNFEVIDLGVMVPAQKILDAAREHDADIIGLSGLITPSLDEMVNFAVEME
REGLQIPLLIGGATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDRQRPALLEA
TAKDYAALRERHAQKNERPMLTLEKARANRTPIEWDGYTPPVPAQGVGVREFIDYDVAEL
REYIDWQPFFNAWEMKGRFPDILNNPVSGEAARKLYDDAQEMLDTLIKEKWLRANGVIGF
FCANAVGDDIEVYTDESRTEVLTTLHNLRQQGEHRAGIPNRSLGDFVAPRETGLRDYVGA
FAVTAGLGSQDKITEFKADHDDYNAILLESLADRLAEAFAERMHQRVRQEFWGYQPDEQL
DNAALIGEKYVGIRPAPGYPACPEHTEKATLFELMDVTERTGIELTESMAMWPGAAVSGW
YFSHPQSQYFVVGRMAQDQIADYARRKGWTLAEAERWLAPNLGYNPED
NT seq
3747 nt
NT seq
+upstream
nt +downstream
nt
gtgcacgtgacaggccttgagccgaacatccgcccggactgcaccgacgagctgaccgcc
gctctgcagcagcgcatcgtggtgatcgacggcgccatgggcacggcgatccagcgcgac
cgccccgacgaggacggctaccgcggtgaccggttcacggagtggccgacggcgctgcag
ggcaacaacgacctgctcaacctgacgcagccgcagatcatcgagggcatccaccgcgag
tacctggaagcgggcgcggacatcctggagaccaacacgttcaacgcgaacgcggtctcg
ctgtcggactacgacatggccgacctgagctacgagctgaactacgtgggcgccgccctc
gcccgcaaggccgccgacgagtacagcaccccggacaagccccgctacgtcgccggcgcc
atcgggccgacgacccgcaccgcgtccatctcaccggacgtcaatgacccgggcgcccgc
aacgtctcctacgaccagctcgtggccgcctacttggaggctgccaacggcctggtcgac
ggcggctccgatctgatcatcatcgagaccatcttcgactcgctgaacgccaaggcggcg
gtcttcgccgtcgagacgctgttcgagcagcgcggccggcgctggccggtgatcatctcc
ggcaccatcaccgacgcgtccgggcgcacgctgtccggccaggtcaccgaggcgttctgg
aacgcgatccggcacgcgagaccgatcgcggtcggcctcaactgcgccctcggcgcaccg
gagatgcggccctacatcgccgagatggcacgcatcgcggacacctacgtctcctgctac
ccgaacgccggcctgcccaacgccttcggtgagtacgaagagtctccgcagcgccaggcc
tcctacatcgccgagttcgccgaggccggcctggtcaacctggtcggcgggtgctgtggc
accgcgccgccgcacatcgccgagatcgccaaggtcgtcgacggcaaggcgcctcgcgaa
ctgccgcagatcccggtggccacccggctgtccggcctggagccgctgaacatctccgac
agctcgctgttcgtgaacatcggggagcgcaccaacatcaccggctcggcccggttccgc
aacctgatcaaggccgaggattacgacaccgcgttgtcggtggcgctgcagcaggtcgag
gtcggtgcgcaggtcatcgacatcaacatggacgagggcatgatcgacggcgtcgccgcg
atggaccggttcaccaagctgatcgccgccgaaccggacatcagccgcgtcccggtgatg
atcgactcctcgaagtgggaggtcatcgaggccggcctgaagaacgtgcagggcaagccg
atcgtcaactcgatctccctgaaggagggcgaggagaagttcatccgcgaggcccggctg
tgccgcaagtacggcgcggccgtcgtcgtgatggccttcgacgaacagggccaggccgac
aacctggagcgccgcaaggagatctgcgggcgcgcctaccggatcctgaccgaagaagtc
ggcttcccggccgaggacatcatcttcgacccgaactgcttcgctctggccaccggtatc
gaggagcacgccacctacgggatcgacttcatcgaggcgtgcgcctggatcaaggagaac
ctgcccggggtgcacatctccggcggcatctcgaacgtgtcgttctcgttccgcggcaac
aacccggtccgcgaggccatccacgcggtgttcctgttccacgccatcaaggccggcctg
gacatgggcatcgtcaatgccggtgcgctggtgccgtacgactcgatcgaccccgagctg
cgcgagcgcatcgaggacgtggtgctcaaccgccgcgcggatgccgccgagcggctgctg
gagatcgcggagcggttcaacagcaagaactcgggagagggtgacgagcgagctgccgcc
gaatggcgcagcttgccggttcgcgaacgcatcacgcacgccctggtcaagggcatcgac
gcgcacgtcgacgccgacaccgaggaactgcgggccgagatcgatgccgccggcgggcgg
ccgatcgaggtgatcgagggcccgctgatggacgggatgaacgtcgtcggcgacctcttc
ggtgcgggcaagatgttcctgccccaggtggtgaagtcggcccgggtgatgaagaaggcc
gtcgcctatctgctgccgttcatcgaggccgagaaggaggcctccggcgcggccgccggt
aaggacaccaacggcaccatcatcatggcgaccgtcaagggcgatgtccacgacatcggc
aagaacatcgtcggagtcgtgctgcagtgcaacaacttcgaggtgatcgacctcggggtg
atggtgcccgcgcagaagatactcgacgcggccagggagcacgacgcggacatcatcggg
ttgtccggtctgattaccccgtcgctggacgagatggtgaacttcgccgtcgagatggag
cgcgaaggactgcagatcccgctgctgatcggcggcgcgaccacctcgcgcgcccacacc
gcggtgaaggtggcgccgcgccgcagcggcccggtggtctgggtcaaggacgcgtcccgc
tcggtgccggtcgccgcggcgctgctcgacgacaggcagcggcccgcgctgctggaggcc
accgcgaaggactacgcggccctgcgcgaacggcacgcccagaagaacgagcggccgatg
ctgaccctggagaaggcccgggcgaaccgcaccccgatcgagtgggacggctacacgcca
ccggtgcccgcccagggtgtcggggtccgcgagttcatcgactacgacgtggccgagttg
cgcgagtacatcgactggcagccgttcttcaacgcctgggagatgaagggccggttcccg
gacatcctgaacaaccccgtgtcgggggaggccgcccgcaagctgtacgacgacgcccag
gagatgctcgacaccctgatcaaggagaagtggctgagggccaacggggtgatcgggttc
ttctgcgccaacgccgtcggcgacgacatcgaggtctacaccgacgagagccggaccgag
gtgctcaccacgctgcacaacctgcgccagcagggggagcaccgcgccggcatcccgaac
cggtccctgggcgacttcgtcgcccccagagaaacgggcctgcgggattacgtcggcgcg
ttcgccgtcaccgcggggctgggcagccaggacaagatcacggagttcaaggccgaccac
gacgactacaacgcgatcctgctggagtcgctggccgaccggctggccgaggcgttcgcc
gaacggatgcaccagcgggtacgccaggagttctggggttaccagcccgacgagcaactg
gacaacgcggcgctgatcggggagaagtacgtcgggatccgcccggcgcccggctacccg
gcctgccccgaacacaccgagaaggccaccctgttcgagttgatggacgtcaccgagcgg
accggcatcgagctgaccgaatcgatggcgatgtggcccggggccgcggtcagcggctgg
tacttctcgcacccgcagtcgcagtacttcgtggtgggccggatggctcaggatcagatc
gccgactacgcccggcgcaagggctggaccctggccgaagccgagcgctggctggcaccc
aatctcggctacaacccggaggactga
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