Mycolicibacterium diernhoferi: K0O62_21625
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Entry
K0O62_21625 CDS
T07506
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mdf
Mycolicibacterium diernhoferi
Pathway
mdf00020
Citrate cycle (TCA cycle)
mdf00630
Glyoxylate and dicarboxylate metabolism
mdf00785
Lipoic acid metabolism
mdf01100
Metabolic pathways
mdf01110
Biosynthesis of secondary metabolites
mdf01120
Microbial metabolism in diverse environments
mdf01200
Carbon metabolism
mdf01210
2-Oxocarboxylic acid metabolism
Module
mdf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mdf_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mdf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
K0O62_21625
00630 Glyoxylate and dicarboxylate metabolism
K0O62_21625
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K0O62_21625
Enzymes [BR:
mdf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
K0O62_21625
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
K0O62_21625
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
K0O62_21625
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
K0O62_21625
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QYL21575
LinkDB
All DBs
Position
4583004..4586765
Genome browser
AA seq
1253 aa
AA seq
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MSSSPSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYAPEPIDNSAEAAPAKTSAPA
APEASPTGDAKNDAPAKTAEPKKSEAKTAEPKKPDAKTAEPKKPEPKKPEAKPAQPAAKA
ATDGSENAVLRGAAAAVVKNMNASLEVPTATSVRAIPAKAMIDNRIVINNHLKRTRGGKI
SFTHLLGYAIVQAVKKFPNMNRHFAEVDGKPNVVTPAHTNLGLAIDLPGKDGNRTLVVAA
IKRCDTMKFGQFIAAYEDIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMRGQG
AIIGAGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTVHQLLLD
DEFYDEIFTELSIPYEPIRWRTDNPDSIADKNARVTELIAAYRNRGHLMADIDPLRLDKT
RFRSHPDLDVLTHGLTLWDLDREFKVDGFAGAEYKKLRDVLSVLRDAYCRHAGVEYTHIL
EPEQQRWIQERVETKHDKPTVAEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVI
PMMDAAIDQAAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFGEFEGNLNPSQAHGSGD
VKYHLGATGTYLQMFGDNDIAVSLVANPSHLEAVDPVLEGLVRAKQDMIDFASGDEQDAF
SVVPMMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHIIVNNQIGFTTSPHDSRSSEYC
TDVAKMVGAPIFHVNGDDPEACVWVAKLAVDFRQKFKKDVVIDMLCYRRRGHNEGDDPSM
TQPGMYDVIDTKRGVRKTYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHEI
EPSESVESDQQTPKGLNTAVDKAVLARIGDAHLAAPEDFNVHPRVQPVLDKRREMAYEGK
VDWAFGELLALGSLVAEGKTVRLTGQDVRRGTFTQRHAVIIDRKTGAEFTPLDLLTTDAD
GNPNGGRFMVYDSALSEFAAVGFEYGYSVGNPDAIVLWEAQFGDFVNGAQSIIDEFISSG
EAKWGQLADVVLLLPHGHEGQGPDHTSGRIERFLQLCAEGSMTVAMPSTPANYFHLLRRH
ALDGINRPLIVFTPKSMLRNKAAVSEVRDFTEVKFRSILEEPTYEDGIGDRSKVTRVLLT
SGKIYYELVARKNKEQRDDVAIVRIEQLYPLPRRRLNATLEQYPNVSQYFWVQEEPANQG
AWPTFGLSLPELLPEKLTGIRRISRRAMSAPSSGSSKVHAVEQQEIIDEAFAP
NT seq
3762 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagttcaccttccccctttggacagaacgaatggctcgtcgaagagatgtatcgc
aaattccgcgacgatccttcgtcggtcgatcccagctggcacgaattcctggtggattac
gcccccgaaccgatcgacaactcggcagaggcggcccctgccaagacttccgcgccggca
gcgcccgaggcctccccgaccggcgatgccaagaacgacgctccggccaagacggccgag
cccaagaagtctgaggcgaagacggccgagcccaagaagcccgacgcgaagacggccgaa
ccgaagaagcccgagcccaagaagcccgaggccaagccggcccagcccgcggccaaggcc
gccaccgacggcagtgagaacgccgtgctgcgcggcgccgccgcggccgtggtcaagaac
atgaacgcctcgctggaggtgcccaccgcgaccagcgtgcgggccatcccggccaaggcg
atgatcgacaaccgcatcgtcatcaacaaccacctcaagcgcacccgcggcggcaagatc
agcttcacccacctgctcggctacgccatcgtgcaggcggtcaagaagttcccgaacatg
aaccggcacttcgccgaggtggacggcaagcccaacgtggtgacgccggcccacaccaat
ctgggtctggcgatcgacctgccgggcaaggatggcaaccgcacgctggtcgttgcggcc
atcaagcgctgcgacacaatgaagttcggccagttcatcgccgcctacgaggacatcgtg
cggcgcgcccgggacggcaagctgaccgccgaggacttctccggggtgacgatctcgctg
accaacccggggaccatcggcaccgtgcactcggtgccgcggctgatgcgcggccagggt
gccatcatcggcgccggtgcgatggagtacccggccgagttccagggtgcgagcgaggag
cgcatcgccgaactgggtatcggcaagctcatcaccctgacgtcgacctacgaccaccgc
atcatccagggcgcggaatccggcgacttcctgcgcaccgtgcaccagctgctgctcgac
gacgagttctacgacgagatcttcaccgaactcagcatcccgtacgagccgatccggtgg
cgcaccgacaaccccgactcgatcgcggacaagaacgcccgcgtcaccgaactgatcgcg
gcctaccgcaaccgcgggcacctgatggccgatatcgatccgctgcgcctggacaagacc
cgcttccgcagccaccccgacctcgacgtgctcacccacgggctgacgctgtgggatctg
gaccgcgagttcaaggtggacggcttcgccggcgccgagtacaagaagctgcgcgacgtg
ctgtcggtgctgcgcgacgcctactgccggcacgccggcgtggagtacacccacatcctg
gaacccgagcagcagcgctggattcaggaacgcgtcgagaccaagcacgacaagccgacg
gtcgccgagcagaagtacatcctgtccaagctgaacgcggccgaagccttcgagaccttc
ctgcagaccaaatatgttgggcagaagcgcttctcactggagggcgcggagaccgtcatc
ccgatgatggacgccgcgatcgaccaggccgccgagcacggtctcgacgaggtcgtcatc
ggcatgccgcaccgcggccggctcaacgtgctggccaacatcgtcggcaagccgtacagc
cagatcttcggcgagttcgagggcaacctcaatccgtcccaggcgcacggttccggcgac
gtcaagtaccacctcggcgcgaccggcacctacctgcagatgttcggggacaacgacatt
gcggtatcgctggtcgccaacccgagccacctggaggccgtcgacccggtgctggagggt
ctggtccgcgccaagcaggacatgatcgacttcgcctccggcgacgagcaggacgcgttc
tcggtggtgccgatgatgctgcacggtgacgccgcgttcgccggccagggcgtggtcgcc
gagacgctgaacctggcgctgctgcgtggctaccgcaccggcggcaccatccacatcatc
gtcaacaaccagatcggtttcaccacctcaccgcacgactcgcggtccagcgagtactgc
accgacgtcgcgaagatggtgggagcgccgatcttccacgtcaacggtgacgatccggag
gcctgcgtctgggtggccaagctggccgtcgacttccgccagaagttcaagaaggacgtc
gtcatcgacatgctgtgctaccgccgacgcgggcacaacgagggtgacgacccgtcgatg
acccagcccggcatgtacgacgtgatcgacaccaagcgcggtgtgcgcaagacctacacc
gaagcgttgatcggacgcggtgacatctcgatgaaggaggccgaggacgcgctgcgcgac
taccagggccaactggagcgggtgttcaacgaggtccgcgagctggagaagcacgagatc
gagccgagcgagtcggtcgagtccgatcagcagaccccgaaggggctgaacaccgccgtg
gacaaggcggtgctggcccgcatcggcgacgcacacctggccgcaccggaggacttcaac
gtccacccgcgcgtgcaaccggtgttggacaagcgccgcgagatggcctacgagggcaag
gtcgactgggcgttcggcgagctgctcgcgctgggttcacttgtcgccgaaggcaagacg
gtccgcctcaccggccaggacgtccgccgcggcacgttcacccagcgccacgccgtcatc
atcgaccgcaagaccggcgccgagttcaccccgctggacctgctgaccaccgatgccgac
ggcaaccccaacgggggtcgtttcatggtctacgactcggcactgtccgagttcgccgcg
gtgggcttcgagtacggctactcggtgggcaacccggacgcgatcgtgttgtgggaggcc
cagttcggcgacttcgtcaacggcgcccagtcgatcatcgacgagttcatctcctccggt
gaggccaagtggggtcagctcgccgacgtggtgctgctgctaccgcacggacatgagggc
cagggccccgaccacacctcggggcgcatcgagcggttcctgcagctgtgcgccgagggc
tcgatgacggtcgccatgccgtcgacaccggcgaactacttccacctgctgcgccggcac
gccctggacggcatcaaccggccgctgatcgtcttcaccccgaagtcgatgctgcgcaac
aaggccgccgtcagcgaggtgcgggacttcaccgaggtcaagttccggtcgatcctggag
gaacccacctacgaggacggcatcggcgaccggtcgaaggtgacccgggtgctgctcacc
agcggcaagatctactacgagctggtggcccgcaagaacaaggagcagcgcgacgacgtc
gcgatcgtgcggatcgagcagctctacccgctgccgcggcgccggctcaacgccaccctg
gagcagtaccccaatgtgtcgcagtatttctgggtgcaggaagagccggccaaccagggc
gcctggccgacgttcgggctctcactgccggagttgttgccggagaagctgaccgggatc
aggcggatctcgcggcgtgccatgtcggcgccgtcgtcgggctcctcgaaggtgcacgcc
gtcgaacagcaggagatcatcgacgaggcgttcgccccgtaa
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