KEGG   Methylorubrum extorquens DM4: METDI4118
Entry
METDI4118         CDS       T00947                                 
Name
(GenBank) multidrug efflux system protein (acrB ou acrF)
  KO
K18138  multidrug efflux pump
Organism
mdi  Methylorubrum extorquens DM4
Pathway
mdi01501  beta-Lactam resistance
mdi01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:mdi00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    METDI4118
   01503 Cationic antimicrobial peptide (CAMP) resistance
    METDI4118
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mdi02000]
    METDI4118
   01504 Antimicrobial resistance genes [BR:mdi01504]
    METDI4118
Transporters [BR:mdi02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   METDI4118
Antimicrobial resistance genes [BR:mdi01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    METDI4118
SSDB
Motif
Pfam: ACR_tran MMPL SecD_SecF_C NOMO1-like_1st
Other DBs
NCBI-ProteinID: CAX25751
UniProt: C7CD21
LinkDB
Position
complement(4050881..4054045)
AA seq 1054 aa
MARFFIDRPVFAWVVALFILLGGALSIPQLPIAQYPIIAPPAIALSTSYPGASVENLYTG
TTRLIEDELNGAANILSFESASDSFGVVEITASFQPGTDPGYAGVEVQNRLKRVEARLPA
EVRQQGILVEEASAATLNIITLVSTDGKTDEVGLGDFLIRNVINEIRRIPGVGRATLYST
ERALRIWIDPDKLRGLSLNAADVTKAIGRQNVQIASGAVGAQPSPERHAVNFPIIVKGQM
TEPEAFGAIVLRANPDGSNVRLRDVARIELGGDDYKFTTRLNGGPAAGISVTLAPDGNAI
ETAKAIRAKMVELSQFFPDTVKWDIPYDITPAVDASIEKVLHTLVEAVVLVFVVMFVFLQ
NIRYTLIPTIVVPIALFGTCTVMLLAGFSVNVLTMFGMVLAIGILVDDAIVVVENVERIM
NEEGLPPKEATRKAMSQITGAIIGITLVLIAVFIPMAFFPGSVGIIYRQFSIAMVTSIAF
SALLALSLTPALCATMLKPIEKGHGHAKGGVFGWFNRFVDRETARYGRGVAWFIRKSGRV
MLIYLVLVAGVAYAFMRLPEGFLPLEDQGFFTVDIQTPPGSSFNRTEAAVKKVEDYLLAQ
PGVATVTVINGFSFSGQGQMTSQAFVTLKPWSERDAANSAAKLVEGTNKALGGYKDAVIQ
ALEPPPIDNLGNASGFSFRLQDRAQKGYSALMAAQEQLLSLARKSPVLTKVYVEGLPPAP
EAELIIDREKAAALGVDFEDINNTIQVNLGSVYVNDFPNRGKMQRVIVQSEDLQRLHAAD
LLNYSVKNAQGTMVPMSSFADLKWGVGPAQIIGFNGYQSVRITGDPAPGYTSGDTIKEME
RLMTFLPKGFGYAWTGQSLQEKEAGSQASLLLALSVLIVFLCLAALYESWSIPISVLLVI
PLGVIGSVAAVYLRGMPNDVYFKIGLITIIGLSAKNAILIVEFARDLWKPGTNIVQATIQ
AATLRFRPIVMTSLAFIFGVVPLAIATGASSKSQQAIGTGVMGGMISATVLAVFFVPVFF
VVVMRLFKRKEVAAGENAEQVPAPAHHGHSVPAE
NT seq 3165 nt   +upstreamnt  +downstreamnt
atggctcgcttcttcatcgaccggccggtcttcgcctgggtcgtcgccctcttcattctg
ctgggcggcgcgctctcgatcccgcaactgccgatcgcccagtacccgatcatcgcgccc
cccgcgatcgcgctctcgacctcgtatcccggcgcctcggtggagaatctctacaccggc
acgacgcgcctcatcgaggacgagctcaacggtgcggccaacatcctgagcttcgaatcg
gcctccgactcgttcggcgtggtcgagatcaccgcgagcttccagcccggcaccgatccc
ggctacgccggcgtcgaggtgcagaaccgcttgaagcgcgtcgaggcgcgcctgccggcc
gaagtgcgccagcagggtatcctcgtggaggaagcctcggccgcgacgctgaacatcatc
acgctcgtctccaccgatgggaagaccgacgaggtggggctgggcgacttcctgatccgc
aacgtcatcaacgagatccgccgcatccccggcgtcggccgcgcgaccctctactcgacc
gagcgggcgctgcggatctggatcgacccggacaagctgcgcggcctctcgctgaacgcg
gccgacgtgaccaaggcgatcggccgtcagaacgtgcagatcgcgtcgggtgccgtcggc
gcgcagccctcgcctgagcgccacgccgtcaacttccccatcatcgtcaaggggcagatg
accgagccggaggcgttcggcgccatcgtgctgcgggccaatcccgacggctccaacgtg
cgcctgcgcgacgtcgcccggatcgaactcggcggcgacgactacaagttcaccacccgc
ctcaacggcggcccggcggcgggcatctccgtgacgctggcgcccgacggcaacgccatc
gagacggcgaaggccatccgcgccaagatggtggagctgtcgcagttcttccccgacacg
gtgaagtgggacatcccctacgacatcacgcccgcggtcgatgcctcgatcgagaaggtg
ctgcacacgctggtcgaggcggtggtgctggtcttcgtcgtgatgttcgtgttcctccag
aacatccgctacaccctcatcccgaccatcgtcgtgccgatcgccctgttcggcacctgc
accgtcatgctgctcgcgggcttctccgtgaacgtgctgaccatgttcggcatggtgctg
gccatcggcatcctcgtcgatgacgccatcgtcgtggtcgagaacgtcgagcgcatcatg
aacgaggagggtctgcccccgaaggaggcgacccggaaggcgatgagccagatcacgggg
gcgatcatcggcatcaccctggtgctgatcgccgtgttcatcccgatggcgttcttcccc
ggctcggtcggcatcatctaccggcagttctcgatcgcgatggtgacctccatcgccttc
tcggccctgctcgccctttcgctgaccccggcgctctgcgccacgatgctgaagccgatc
gagaaggggcatggccacgccaagggcggcgtgttcggatggttcaaccggttcgtcgac
cgggagaccgcccgatacggccgcggcgtggcgtggttcatccggaagtccggccgggtg
atgctgatctacctcgtgctggtcgcgggcgtggcctacgccttcatgcgcctgcccgaa
ggcttcctgccgctcgaggatcagggcttcttcaccgtcgatatccagaccccgccgggc
tcctccttcaaccgcacggaagcggcggtgaagaaggtcgaggattatctcctggcccag
ccgggcgtggcgacggtcaccgtcatcaacggcttctccttctccggccagggccagatg
acgagccaggccttcgtcacgctcaagccctggagcgagcgcgacgcggcgaattccgcc
gccaagctggtggaagggaccaacaaggcgctcgggggctacaaggatgccgtgatccag
gcgctggagccgccgccgatcgacaacctcggcaacgcctcgggcttctcgttccgcctg
caggaccgggcgcagaagggctactcggcgctgatggcggcccaggagcagctgctctcg
ctcgcccgcaagagccccgtgctgacgaaggtctacgtcgagggcctgccgcccgcgccc
gaggccgaactcatcatcgaccgcgagaaggcggccgcgctcggcgtcgatttcgaggac
atcaacaacacgatccaagtcaatctcggctcggtctacgtcaacgacttccccaatcgc
ggcaagatgcagcgcgtgatcgtgcagtccgaggatctccagcgcctgcacgcggcggac
ctgttgaactactcggtcaagaacgcgcaggggacgatggtgccgatgtcctccttcgcc
gacctgaaatggggcgtcgggccggcgcagatcatcggcttcaacggctaccagtcggtg
cgcatcaccggcgatccggcccccggctacacctccggcgacaccatcaaggagatggag
cggctgatgaccttcctgccgaagggcttcggctacgcctggaccgggcagtcgctccag
gagaaggaggcgggctcccaggcctcgctgctgctggcgctgtcggtgctgatcgtgttc
ctgtgtctggccgcgctctacgagagctggtcgatcccgatctcggtgctgctggtgatc
ccgctcggcgtcatcggctcggtggcggcggtgtatctgcgcggcatgcccaacgacgtc
tacttcaagatcgggctcatcacgatcatcggcctctcggccaagaacgcgatcctgatc
gtggagttcgcccgcgacctgtggaagcccggcaccaacatcgtccaggcgacgatccag
gcggcgacgctccgcttccgcccgatcgtgatgacctcgctcgccttcatcttcggcgtg
gtgccgctggcgattgccaccggcgcctcctcgaagagccagcaggccatcggcacgggc
gtgatgggcggcatgatctcggccaccgtgctcgcggtgttcttcgtgccggtgttcttc
gtggtggtgatgcgcctgttcaagcgcaaggaggtcgccgcgggcgagaacgcggagcag
gtgcctgctccggctcatcatgggcattcggtgccggcggagtag

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