KEGG   Malus domestica (apple): 103404863
Entry
103404863         CDS       T03194                                 
Name
(RefSeq) auxin transport protein BIG-like
  KO
K10691  E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
Organism
mdm  Malus domestica (apple)
Brite
KEGG Orthology (KO) [BR:mdm00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mdm04121]
    103404863
Enzymes [BR:mdm01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     103404863
Ubiquitin system [BR:mdm04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   UBR box proteins
    103404863
SSDB
Motif
Pfam: E3_UbLigase_R4 UBR4_TPR UBR4_Ub UBR4 ZZ zf-UBR_1 zf-UBR
Other DBs
NCBI-GeneID: 103404863
NCBI-ProteinID: XP_008342052
LinkDB
Position
17:join(5220695..5220953,5221205..5221311,5222749..5222914,5223008..5229069,5229192..5229806,5229932..5230112,5230707..5230941,5231031..5235575,5235683..5235905,5236232..5236633,5237127..5237270,5237365..5238384,5238932..5239435,5239540..5240355)
AA seq 5092 aa
MAETFARLAESIYSDGKPISSTDLLQRLRSSPDSIRPGLENLLPILKRGVEAAGDGKLGL
QSWTDSQIQAVYSISYAVASSSRSLSVEQADAVIVAIVQQSLEFAVCYLERSEFSSEDMS
IQNNMVQLLEMALINRMDKTPDELRPCSVDSLVDLLPTVTRSSCGNDIDNYIKCGPQGVN
CSRAEKPVDRLFMSLASECIQSDKQTTGFGGPAFHQDFNKLVFLSQHWAAVHAGCIQRLI
LLCKEHIMLPDTFDEKIAGPYICKRLSFSLRIIKLLRSLTKDIPYIEHDVSLLQAVASFA
DAVPGLFRPCFEFVNSHVAVEGSFESLNLLILEDFLELVRVTFCNSSVFLNVQVCVVASI
LDNLDASVWRYNKTAANLKPPLAYFPRVVVHILMLIHDLKRQTSRAINWKKLDTELTGSS
VNFLDSPSCLVHSEKIPLLQSYTFEHLVQIIFPSSKQWMDDLMHLLFFLHSEGVKLRPKV
ERSYSSCAKTTCSSELENVVCHEDEALFGDLFSESGRGSTDGYDQPPVVLNSSSSQSNMP
MEAATELLRFLKGFVFSPEWHPSVFEDGCVKLSRSHIDIFLSLLHGQGYPEDRSPECYSL
SHEEKKIGHTHELCFDLLQDLISHHALPDSLEEYFVEKILNVENDIFVYNNQTLTLLAHT
LFCRVGLSGSRLRTQIFRGFVDIIVEKTKTVSLKSPTLKELLDALPCAFHIEILLMAFHL
SSEEEKKSQAKLIFSALRAVGAPTSGFNSMHMSCWALLVSRLILVLRHMIFYPQTCPSSL
LVHLRSKLREAPCSSSQLGVNDHLSSWVSVVFKNVMSASFEEESDISPLIHQLIDTSAFP
ASQSLDRVDVDSLCLNWYEICSTISSILGLWKGKQAAVVEDLIVERYIFILCWDFPTLST
SKEHQLPSSSNAQTFDVSDMENFFFFSHSILGHQAAVDVKTNSQVVVQLLQHLSEHTEEV
GWGFLRNARWLSLALTLLDVGISRYGMKNKVPGVGSDWIENTSKDNEYIAVAEGLIASLM
NTDQVSILLKTFSSLLNSYLLAYQKAFVATFGNSQEDADGFSPLLLFKHSGFDKCLQDEL
GKTGTYSFHLESVIDPLTKFDAIIDKGASGILCRASWQCMLHGFPLNLRTSSGVLLSCIL
NIRGIISILVGLLKMKDMIGNVCLENEVLHQILDMAVTIKSDRIFESIHGKCETIYDSLS
VGLGGSDCANLILLEHLEGFLRDINARGVSDSTIHECIITKAIDTMDSLRKDPAKVDYFK
FYLGIEDVPEQVKELFGVQRSNLLVLIDSLHNCYSETVNIKVLNFFVDLLTGEQFPDLKQ
KIQNKFLGMDLLLLSKWLEKRLLGCVTEASGGVNSAKGSSVFLRESTMNFILCIVSSPPN
LKSTELQSHIFEAVLVSLRPAFLQFDIHVAKSFFQFVVQLSKGDASVRLLLKKTIMLMEK
LSGNDCLLPGLKFLFGFFGSVLSDCGSGKNTLERSSGKPLPVNALGCVGPMASSPVGSRK
DSEALVLSSNQEGGSIALECDATSVDEDEDDGTSDGEVASLDKDDEEDTNSERALASKVC
TFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHRGHRVVYSRSSRFFCDCGAGGVR
GSNCQCLKPRKFTGSSSTPVRSASNFQALLPFTEDGEQLPETDSDFDEDASTDVDNSLRL
SIPKELQDAITPLLEELDVEGQVLELCSSLFPYVTSKRDSNLSKNNKIALGKDKVLSFGV
DLLQLKKAYKSGSLDLKVKADYSNAKELKSHLASGSLVKSLLSVSIRGRLAAGEGDKVAI
FDVGQLIGQATIAPVTADKTNVKPLSKNVVRFEIVHLTFNPVVENYLAVAGYEDCQVLTV
NPRGEVTDRLAIELALQGAYIKRVDWVPGSQVQLMVVTNRFVKIYDLSQDNISPIHYFTL
PDDMIVDATLVVASQGRMFLIVLSEHGRLFRLELSVEGNVGATPLKEVIQIQDKVIDAKG
SSLYFSSAYKLLFLSYQDGTTLVGRLSPNASSLSEISTIYEEEQDGKQRSAGLHRWKELL
ADSGLFVCFSSIKSNSAIAVSMGSHELFAQNLRHAVGSTSPLVGVTAYKPLSKDKIHCLV
LHDDGSLQIYSHTPMGVDASASATAEKVKKLGSGILSNKAYAGINPEFPLDFFEKTVCIT
ADVKLGGDAIRNGDSEGAKQSLASEDGFLESPSPAGCKISVSNSNPDIIMVGFRVHVGNT
SANHIPSDISIFHRVIKLDEGMRSWYDIPFTVAESLLADEEFTITVGPTFNGSALPRIDC
LEVYGRAKDEFGWKEKMDAVLDMEARVLGCNSLLSESGKKRRSMQSAPMQEQVIADGLKL
LSRIYSCRSRGSSKVEEFSPELSKLRCKQLLEKIYESDREPLLQAAACHVLQAVFPKKDT
YYQVKDTMRLLGVVKSTSVLSSRLGVGGTAGPWIIEEFTAQMRAVSKIALHRCSNLATFL
EIHGSEVIDGLFQVFWGILDLEQLDTQTMNNIVVSSVDLIYCYAECLALHGKGTGLHSVG
PAAVLFKKLLFSSNEAVQTSTSLAISSRLLQVPFPKQTMLATDDAVENVVSAPVHADTTG
GNAQVMIEEDSITSSVQYCCDGCSTVPILRRRWHCTICPDFDLCEACYEVQDADRLPPLH
SKDHPMTAIPIEVESLGGDGSEFHFTPDDASDSSILPASADARTQNSAPTIHVLEPNESG
EFSGSVNDSVSISASTRALNSLLLSELLEQLKGWMHLMSGVRAIPVMQLFYRLSSAVGGP
FTDTSKPESLNLEKLIRWFLDELSLNQPFVAKSRSSFGEVAILVFMFFTLMLRNWHQPGS
DSSMPKPSGTTDTHDKSIIQISPSISVAASSSFDDQKKNDFASQLLQACNSLRQQSVVSY
LMDILQQLVHVFKSPSVNYENAGPGSGCGALLTVRRDVAAGNFSPFFSDSYAKAHRTDIF
VDYHRLLLENTFRLVYTLVRPEKQDKTAEKEKVSKISSGKDLKLDGYQDVLCSYINNPHT
TFVRRYARRLFLHLCGSKTHYYTVRDSWQFSSEMKKLYKHVNKSGGFQNHLSYERSVKIV
KCLSTMAEVAAARPRNWQKYCLKHTDFLPFLINGVFYLAEESVIQILKLLNLSFYTGKDV
GHLLQKTEAVDSGINSNKSGTQSQDPKKKKKGEEGTESGSEKSYVDMESLIYIFTDKGGD
VLKQFIDCFLLEWNSRSVRAEAKCVLYGVWHHAKPSVKETMVVTLLEKVKCLPMYGQNIV
EYTELITWLLGKVPDVSSKQQSSELVDRCLTPDVVKCIFETLHSQNELLANHPNSRIYNT
LSGLVEFDGYYLESEPCVACSSPEVPYSRMKLESLKSETKFTDNRIIVKCTGSYTIQTVT
MNVHDARKSKSVKVLNLYYNNRPVADLSELKNNWSLWKRAKSCHLTFNQTELKVDFPIPI
TACNFMIELDSFYENLQALSLEPLQCPRCSRPVTDKHGICSNCHENAYQCRQCRNINYEN
LDSFLCNECGYSKYGRFEFNFMAKPSFTFDDMENDEDMKRGLAAIEAESENAHRRYQQLL
GFKKPLLKIVSSVGEIEIDSQQKDSVQQMMVSLPGPACKINRKIALLGVLYGEKCKTAFD
SVSKSVQTLQGLRRVLMNYLHQKQSVNGVAASRFVVSRSPNNCYGCASTFVTQCLEVLQV
LSKHPNSKRQLVAAGILTELFENNIHQGPKTARVQARAVLCAFSEGDINAVTELNSLIQK
KVMYCLEHHRSMDIALATREELSLLSEVCSLTDEFWESRLRVVFQLLFSSIKLGAKHPAI
SEHVILPCLRIISQACTPPKPDVPDKEPNTGKATTGLQSNDESNSNMSGSLGGHGDGTKS
AEPLDKNWDASQKTQDIQLLSYAEWEKGASYLDFVRRQYKVSQSVKGGSQKTRPQRQEFL
ALKYALRWKRCTSKTAKNDLSAFELGAWVTELALSACSQSIRSEMCMLISLLCAQSASRR
FRLLNLLVSLLPATLSAGESAAEYFESLFKMIDSEDARLFLTVRGCLGTICKLITQEVGN
VESLERSMRIDISQGFILHKLIELLGKFLEVPNIRSRFMRDNLLSEVLEALIVIHGLVVQ
KTKLISDCNRLLKDLLDSLLLESSENKRQFIRACICGLQNHVEERKGRTCLFILEQLCNL
ICPSKPEPVYLLVLNKAHTQEEFIRGSMTKNPYSSSEIGPLMRDVKNKICHQLDLLGLLE
DDYGMELLVAGNIISLDLSIAQVYEQVWKKSSQSSNAMANTTLLSPNAVPSARDSPPMIV
TYRLQGLDGEATEPMIKELEEDREESQDPEVEFAIAGAVREYGGLEIILSMIQHLRDDFK
SNQEQLVAVLNLLMHCCKIRENRRALLRLGALGLLLETARHAFSVDAMEPAEGILLIVES
LTMEANESDNISITQSALTVTSEETGEQAKKIVLMFLERLSHPLGLKKSNKQQRNNEMVA
RILPYLTYGEPAAMEVLIQHFSPPLQDWKEYDRLQREHEDDPKDESIAQQAAKQRFTLEN
FVRVSESLKTSSCGDRLKDIILERGITGVAVRHLRDSFSAAGQAGFKSSAEWAMGLTLPS
VPLILSMLRGLSTGHLATQKCIDEGGILPLLHALEGVAGENEIGARAENLLDTLSNKEGK
GDGFLEEKVRRLRHATRDEMRRRALRKREELLQGLGMRQELASDGGERIVVSRPLLEGLE
DVEEEEDGLACMVCREGYSLRPTDLLGVYSYSKRVNLGAGTSGSARGECVYTTVSYFNII
HFQCHQEAKRADAALKNPKKEWEGATLRNNESLCNSLFPVRGPSVPLAQYVRYVDQYWDN
LNALGRADGSRLRLLTYDIVLMLARFATGASFSAECRGGGRESNSRFLPFMIQMARHLLD
QGSPSQRHTMAKSLTAYLSSSASDSRTSTPEKQPSMGSEETVQFMMVTSLLSESHESWLQ
HRRAFLQRGIYHAYMQHTHGRSAGRTSSSSSPIVNIESGNTSQSPSAEIGGADELLSVIR
PMLVYTGLIEQLQRFFKVKKPPNAAPAPTEGTSRVSEGDDLEVWEVVMKERLSNVKEMVD
FSKEMLSWLDEMSSASDLQEAFDIIGVLADVLSGAITNCEDFVRAAIDAGRG
NT seq 15279 nt   +upstreamnt  +downstreamnt
atggccgagaccttcgccagactcgccgagtctatctactccgacggcaagcccatctcg
tccactgatctcctgcagagactgcgctcctcccccgactcgatcagaccgggactcgag
aaccttctcccgattctaaaacgtggcgttgaggccgccggagacggcaagctagggctc
caatcatggaccgattctcaaattcaagccgtgtattcgatttcctacgccgtcgcttcc
tcctctcgatctctgtccgtggagcaagcggatgcggtaattgttgctattgtgcaacag
tcgttggaatttgctgtatgttatttggaaagatcagaatttagcagcgaagatatgagc
attcagaataatatggtgcagcttttggagatggcattgattaatagaatggataaaacg
cctgatgagctgcgaccttgttcggtagatagcctggtggacttgttgccaactgttacc
cgtagttcttgtggtaatgatattgacaactacattaagtgtggtcctcaaggtgtcaat
tgctcaagggcagagaaaccagtggatcgcctgtttatgtctttagcttctgagtgcata
caatcagataagcagaccactgggtttggtggccctgctttccaccaggatttcaacaaa
ttagtttttctatcccagcattgggcagctgttcacgcagggtgcattcaacgtttgatt
ttgctctgcaaggagcacattatgctcccagatacgtttgatgagaagattgctgggcca
tacatctgtaagaggctgtctttcagtttgaggattataaagctacttagaagtctcaca
aaggacatcccttatattgaacatgatgtgtcattgttgcaagcagttgcttcttttgct
gatgcagtgcctgggttgtttagaccttgctttgagtttgtaaatagccatgttgcagtc
gaaggtagttttgagagcctcaatctgttgatattggaagactttcttgaacttgtccgg
gttactttctgcaacagcagtgttttcttgaatgtccaagtctgtgtggtagcttccata
ctagacaatttagatgcttctgtatggagatataacaagactgctgctaacctgaagccc
ccactagcttattttcctcgtgttgttgtccacatattgatgctcattcatgaccttaag
aggcagaccagtcgggctatcaattggaagaagttagacacagagcttactggaagtagc
gtcaattttcttgattctccgtcatgccttgttcattctgagaaaattcctttactccaa
agttacacatttgaacatctggtgcaaataatattcccttcctcaaagcagtggatggac
gatctgatgcatcttctatttttccttcattctgagggagtaaaactgagaccaaaagtg
gagaggtcatattctagttgtgcaaaaactacttgcagctccgaattagaaaatgtggtt
tgccatgaagatgaagccctttttggagaccttttctctgagagtggtcgtggatctaca
gacggttatgatcagccaccagtggttcttaattctagctctagccagagtaatatgcca
atggaagctgctacggagctgttgaggtttcttaaagggtttgtcttctctcctgaatgg
catccgtctgtttttgaggatggctgtgtgaagcttagcagaagccatattgatattttt
ctgtccttactccacggccagggatatcctgaggataggagtcctgagtgctattccctt
tcacatgaagagaaaaagattgggcatacccatgaactttgttttgatttgttgcaagac
ctgatctcacaccatgcattacccgattcactggaagagtactttgttgagaagattttg
aatgttgagaatgatatttttgtttacaataatcagacccttaccctgctagctcacacc
cttttctgtagggtgggtttgtctggtagccggttgagaacccaaatttttagggggttt
gttgatattattgttgagaagaccaaaactgtttctttaaaatctcctaccttgaaggaa
cttcttgacgcccttccatgtgcttttcatattgagattctccttatggcatttcactta
tcgtccgaggaggaaaaaaaatcacaggcgaaattaatattttctgctcttagagcagtt
ggtgctccaacttcgggttttaacagtatgcatatgtcttgctgggctctactggtttca
aggttgattttagtgcttcgccatatgatattttacccacagacttgtccttcgtccttg
cttgtacatctgcggtccaagttgagggaggctccgtgctccagttcacagcttggggtg
aacgatcatttgtcatcttgggtctcagtggtatttaagaatgtaatgagtgcatcattt
gaagaagagtctgacatcagtcccttgattcatcaactgattgatacatctgccttccct
gcttcgcagtccctagatcgtgtggatgttgactccttatgcttgaactggtacgagatc
tgttcaaccatttcgtcaattctggggttgtggaaaggcaaacaggctgcagtggtggag
gatcttattgttgaaagatacattttcatactttgttgggattttccaactctcagtact
tcaaaggaacatcagcttccttcgagtagcaatgcacagacttttgacgtttctgacatg
gaaaacttctttttcttcagccattcaattctaggtcatcaggctgctgttgatgtgaaa
actaattctcaagttgtagttcagctgcttcagcacttatctgagcacactgaggaagta
ggctggggtttcttgagaaatgcaagatggctgtctttggcactcaccttgcttgatgtt
gggatctcgaggtatggcatgaagaataaagtcccaggagtgggttcagactggatagag
aacacgtccaaggacaatgagtatattgctgttgctgaaggtctgattgcctctttaatg
aacactgatcaagtttcaattttgttgaagacattttcttctttgctgaacagttattta
ctggcttatcagaaagcttttgtggctacctttggtaatagccaggaggatgctgatggg
ttttcaccattgttgctttttaagcattcaggatttgacaaatgccttcaggatgagcta
ggaaagactggaacttattcgttccatctggagtctgttattgaccccttgactaagttt
gatgctattattgacaaaggagcttcaggaattttgtgtagggcctcctggcaatgtatg
ctgcatggtttcccactgaatcttcggacttccagtggtgttctcctttcttgcattctt
aacattagagggatcatttccattctggttggtctgcttaaaatgaaagatatgatagga
aatgtctgcttggagaatgaagtgctccatcaaattcttgatatggcagtgacaatcaag
tctgataggatttttgaaagcattcatgggaaatgtgaaaccatatatgatagcttgagt
gtaggtttggggggatcagactgtgccaatttaattctattagagcacctagaaggattt
ttaagggatatcaatgccagaggagtaagtgatagcactatccatgagtgcataattacc
aaagctattgatacaatggatagcctaaggaaagaccctgctaaggttgattattttaaa
ttctatcttggtatagaagatgtccccgagcaggtgaaggagctatttggtgtgcagcgt
agcaatctgctggttctaattgactctctacataattgttactctgaaacagttaacata
aaggttcttaacttttttgttgatctgttaactggagagcagtttcctgatcttaaacag
aagatccaaaacaagtttcttggcatggacttgcttttgctttccaaatggttggagaag
aggctgttaggttgtgtaacagaagcttcaggtggagttaatagtgcaaaaggaagttcc
gtctttctcagagagtcaaccatgaactttattttatgcattgtatcgtcacctcctaat
ttgaaatcaacagaactgcagagtcatatttttgaagctgttctggtttcccttagacct
gcatttttgcaatttgatattcatgttgccaaatcatttttccaatttgttgttcaactg
tctaagggggatgcttcagtgagattgcttttaaagaagaccataatgctgatggaaaag
ttatctggcaatgattgcctgctaccaggcctgaagtttctttttggctttttcgggagt
gtcttaagtgattgtgggtctggcaagaataccttagaaaggtcgtctgggaagcctctg
cctgtaaatgctcttggttgtgtgggacctatggcttcaagcccagtaggatcaaggaaa
gactccgaggcattggtcctttcttctaatcaagaaggtggttccattgctcttgaatgt
gatgcaacttctgtagacgaggatgaggatgatggaacttctgatggtgaggttgccagc
ctggacaaggatgatgaagaggatactaacagtgaaagggcccttgcttctaaagtttgc
acttttacttctagcggtagcaatttcatggaacaacactggtacttctgttatacatgt
gatctgacagtgtcaaaaggctgttgctctgtgtgtgcaaaagtttgtcatcgaggtcat
cgtgttgtttattctcgctctagtcgtttcttttgtgactgtggagctgggggtgttaga
ggaagcaactgtcagtgcttaaagccacgcaagttcactggaagtagtagcactccagtc
cgtagtgctagtaatttccaggcccttttacccttcacggaggatggagagcagctgcct
gaaactgattcagattttgatgaggatgctagtactgatgtagataactctctcagacta
tccatcccgaaagagcttcaagatgcaatcacaccattgcttgaagaacttgatgttgaa
ggtcaggtgcttgaactttgctcttcattgttcccatatgtaactagtaaaagagactcg
aacttgtcaaaaaataataaaattgctcttggtaaagacaaagtgctgtcttttggtgtt
gatctcttgcaattgaagaaggcatataaaagtggatccttagacctgaaggtaaaggcc
gactattcaaatgccaaagaacttaaatcacatttagctagtgggtctcttgtgaaatcc
ttgctcagtgtcagtattcgagggcgacttgctgctggagaaggtgataaagttgctata
tttgatgttgggcagttgattggacaggccaccattgcaccagtgacagcagacaagacc
aatgttaagcctctctctaagaatgttgttcggtttgaaatcgtgcatcttactttcaat
ccagtggtagagaattatcttgcagtagcaggctatgaagattgccaggtcctcactgtt
aatcctcgtggtgaagtgactgaccgtcttgccattgaactggcactgcaaggtgcatat
attaaacgggttgactgggttccaggttctcaggttcaattgatggtcgttaccaacaga
tttgtcaaaatatatgatctatctcaggacaacatcagtcctatacactactttacactg
ccagatgatatgattgtggatgcaacacttgttgtggcttctcaggggaggatgtttctt
attgttctctcagaacatggaaggctgtttaggctagaattgtcagtggaaggtaatgtt
ggggctacacctttgaaggaagtaatccagatacaagataaagtaatagacgcgaagggc
tcatcgttgtacttttcttcagcgtacaaattacttttcctatcttatcaagatggcact
accttggtaggccggctaagccccaatgcctcatctctaagtgagatatctaccatatat
gaggaggaacaagatggtaaacagcggtctgctggacttcatcgttggaaggaattgctg
gctgacagtggtttatttgtttgcttctcaagtataaaatcaaactctgccattgctgta
tctatgggatcgcatgagttatttgcacagaacttgcgacatgcagtgggttcgacttca
cctctagttggagtaactgcttataagcctttatccaaagataagattcactgtcttgtt
ttacacgatgatggtagccttcagatatactcacatacaccaatgggagtcgatgccagt
gctagtgcaacagcagagaaagtaaaaaaattgggttctggaattctcagcaacaaggct
tatgctggcattaacccagaattcccacttgattttttcgagaaaacagtgtgcataaca
gcagatgtgaaattgggtggtgatgccatcagaaatggtgattctgaaggggctaagcag
agcttggcatctgaggatggctttctagaaagtccgagccctgcaggatgtaagatatct
gtctccaattcgaaccctgatatcatcatggttgggtttcgtgtgcatgtgggtaataca
tcagcgaaccatataccttctgatataagtattttccatagggtgatcaaattagatgag
ggcatgcggtcttggtatgatataccatttacagttgctgagtcactccttgctgacgaa
gaatttacaatcactgttggacccacatttaatggatctgctttgcctagaattgactgt
cttgaagtatacggtagagctaaagatgaatttggctggaaagagaaaatggatgctgta
cttgatatggaggctcgtgtgcttggttgtaattcattgctttcagaatctgggaaaaaa
cgccggtcaatgcagtctgctcctatgcaggagcaggtcatagctgatggtcttaagctt
ctatccaggatttactcatgtagatctcgtggtagctcaaaagttgaggaatttagtccg
gagctgagcaaactcaggtgcaagcagttattggaaaaaatatatgagagtgatcgagag
cccttgttgcaggctgctgcttgccatgtcttgcaggctgtgttccccaaaaaagacact
tactatcaagttaaggacacgatgcggcttcttggagtggtgaaatcaacctctgtactc
tcttcaaggcttggggttggtggtactgcagggccatggataattgaagagtttacagcc
cagatgcgtgcagtatctaagattgcattgcaccgttgctcgaatctggcaactttcttg
gagatacatggttctgaagttattgatgggctttttcaagttttttggggaattttggac
ttggagcagcttgacacacaaacaatgaacaacattgttgtatcttcggtagatctgatt
tattgttatgctgaatgcctggctttacatggaaagggtacagggttacactctgttgga
cctgctgctgtattattcaaaaagcttctcttttcgtccaatgaggctgttcaaacatca
acaagcttggctatatcttcaaggttgcttcaggttccatttccaaagcaaactatgttg
gccaccgatgatgctgtagaaaatgtagtatctgcacctgtgcatgctgacacaactggt
ggaaatgcccaagtcatgattgaagaagattctatcacttcatccgttcaatactgttgt
gatggttgctccactgttcctatactcagaaggcgatggcattgtactatttgtcctgat
tttgatctttgtgaggcatgctatgaagtacaggatgcagatcgtctccctccactgcac
tccaaagatcatcctatgacagcaatacctattgaagtggaatcattaggcggagatggc
agtgagtttcacttcacaccggatgatgcaagtgattcaagcatattgccagcatctgca
gatgccaggactcagaattctgccccaacaattcatgtcctggaacccaacgagtctggg
gagttttctggttcagtgaatgactctgtttcaatttctgcttcgacacgggctttaaat
tctttacttctctctgaacttcttgaacaattaaaagggtggatgcacttgatgtcgggg
gtccgggcaatccctgttatgcagctcttctacagattatcatctgctgttggtggacct
ttcacagacacctcgaagcctgaaagcttaaatctggagaaattgattagatggtttttg
gatgagcttagtcttaaccaaccttttgttgccaaatcccgctcttcatttggggaagtt
gcaatacttgtattcatgttctttaccttaatgctacgaaactggcaccagcctggcagt
gatagttccatgccaaaacctagtgggacaacagatacacatgataaaagcatcatccag
atttcaccctccatctcagttgctgcttcatcttcttttgatgatcaaaagaaaaatgac
tttgcatcgcagctgctccaagcatgcaattctcttaggcaacagtctgttgtcagttac
ctgatggatatactgcaacagttggtgcatgtttttaagtccccttctgttaattatgaa
aacgcaggacctggttctggatgcggtgctctattaacagttcgaagggatgtagcagct
ggcaatttttctcctttcttttcagactcatatgcaaaagcccaccgtacagatatattt
gtggactaccataggttgctgttggagaataccttccggctggtatacaccttggttaga
cctgaaaagcaagacaagacggcggagaaagagaaggtttcaaagatctcctctggcaag
gatttgaagctagatggatatcaagatgttctctgcagttacattaacaatcctcacaca
actttcgtgagaagatatgcaaggaggcttttcctccatctctgtggaagcaaaactcac
tattacactgtgcgagactcctggcaattctcaagtgagatgaaaaaactttacaaacat
gtaaacaagtcgggtgggtttcaaaatcatttgtcatatgagagaagtgttaagatagtt
aagtgtctctctacaatggctgaagtagctgcagcacgacctcgtaactggcagaagtac
tgtttgaaacatacagatttcctaccattcttgattaatggagtgttctatcttgcagaa
gagtcagttattcagattttgaagctgttgaatctttccttttacacgggaaaggatgtt
ggtcatttattacagaaaactgaagctgtggattcaggtattaattcaaacaaatcaggg
acacaatctcaggatcccaaaaagaagaagaaaggtgaagaaggaacagaatctggttcg
gaaaagtcttatgtggatatggagtctctgatatatatcttcactgacaagggtggagat
gtcttgaagcaattcattgattgctttttgcttgaatggaattctaggtctgtgcgtgca
gaggccaagtgcgttctttatggtgtgtggcatcatgctaagccatcagtcaaggaaact
atggtggtgactctcttggagaaagtaaaatgtctaccaatgtatggtcaaaatattgtt
gagtatactgaacttatcacatggttgctgggtaaagttccagatgtcagctcaaagcaa
cagagcagtgagcttgtggatcgatgcttaacccctgatgtagtcaaatgcatctttgag
acacttcattcacaaaatgagcttttagctaatcatccaaattcccgcatatacaacact
ttaagtggattagtcgaatttgatgggtactatcttgagagtgagccttgtgttgcctgc
agctctccagaggtgccatacagcaggatgaagcttgaaagtctgaaatctgaaacaaag
ttcacggataatcgcatcatagtgaaatgcactgggagttacaccatccagacagtgacc
atgaatgtccatgatgcgcgaaagtctaaatcagtgaaagtcttgaacctgtattacaat
aatcgaccagtggctgacttgtcagagttgaaaaataattggtctctgtggaaacgtgcc
aagagttgccatctcactttcaatcagactgaactgaaagtggactttcccattccaata
acagcttgtaacttcatgattgagctggattccttctacgaaaatctccaggctttgtct
cttgaaccattgcaatgcccacgttgcagtcgacctgtcactgataagcatggtatttgt
agcaattgccatgagaatgcttatcagtgcaggcagtgccgcaacattaattatgaaaat
ctggattcctttctatgcaacgagtgtggctatagtaaatatggtagatttgagttcaat
ttcatggcaaagccaagttttacttttgatgacatggagaatgatgaagatatgaagaga
gggttggctgctatagaagctgaatcagaaaatgctcataggagatatcagcaacttcta
ggattcaagaagcccctgcttaagattgtgtcgagtgtcggtgagattgaaatagactca
caacagaaggattcagtgcagcaaatgatggtctccttacctgggcctgcatgcaagatt
aatcgtaaaatagctcttcttggtgtcctgtatggtgagaagtgcaaaacagcttttgat
tccgtcagcaagagtgtccagacactgcaagggttacgccgggttttgatgaattatttg
caccagaaacagtctgttaacggagtggctgcttccagatttgtggtttctaggtctcca
aataattgctatggctgtgcttctacatttgtgacgcagtgtcttgaagtcttacaggtc
ctatcaaagcatccaaactccaagagacaacttgttgcggctggcattttaacggaacta
tttgaaaataacattcatcaaggtcctaaaacagctcgtgtccaagctagggccgttctt
tgtgcattctctgagggtgatataaatgcagtgactgagttgaacagcttaattcagaaa
aaggttatgtattgccttgaacatcatcgctccatggacattgctctggccactcgtgaa
gagttgtcattgctgtcagaagtatgttctctcactgatgaattttgggaatcaagattg
cgtgttgtttttcagctgttattttcttctattaaattgggtgctaagcatcctgccatt
tctgagcatgtcattcttccttgtctgaggattatatctcaggcatgtactcctccaaaa
cctgatgtaccagataaagagcctaatacaggaaaagctactactggtttgcagagcaat
gatgaaagtaattcaaatatgtctggatctttgggtggacatggtgatggtaccaagtca
gcagaaccactagataagaactgggacgcatctcaaaagactcaggacattcaattatta
agctatgcagaatgggagaagggagcatcatatcttgattttgttagaaggcagtacaaa
gtgtcgcagtctgttaaaggtggtagccagaagactcgacctcagagacaagaattcctg
gctcttaaatatgcactcaggtggaagaggtgtactagtaagacagccaagaatgacttg
tcagcatttgagctgggggcatgggttacagaacttgctcttagtgcttgttctcaatct
ataaggtcggagatgtgcatgttgataagtctgctctgtgctcagagtgcatcaagacga
tttcggttattgaacttactagtgtccttgctaccagcaactctttctgctggtgaaagt
gctgcggaatattttgagtctctgttcaagatgatagattcagaagatgctcgcctgttt
ttgactgtgcgtggatgtcttggtacaatttgtaaactaattactcaagaagttggcaat
gttgaatctctagaaaggagcatgcgtatcgacatttctcaaggattcatacttcacaag
cttatagagctgcttggtaaatttttggaggttccgaatattcgatccagattcatgcga
gacaatttgctgtcggaagttcttgaggctcttattgttattcacggcttggtagtgcag
aagacaaagttaatcagtgattgcaatcggcttctgaaagaccttttagatagccttctg
cttgaaagcagcgaaaataaacggcagttcattagagcctgcatctgtggtttgcaaaac
cacgtggaggagagaaaaggacgaacttgtctgtttatcctggagcagctctgcaatctg
atatgcccatcaaaaccagagccagtgtatctgctggttctaaacaaggcacatacacaa
gaagagttcattaggggatctatgacgaagaatccctattctagttctgagattggtcct
ctgatgcgtgatgtcaagaacaaaatttgccatcagttggatctgctaggtcttcttgaa
gatgactatgggatggaattgctagttgctgggaacattatctctcttgatttgagcata
gctcaagtctatgagcaagtctggaagaagtcaagtcagtcttccaatgccatggccaat
acaacattgttatctcccaatgctgttccatcagctagagactctccacctatgatagtg
acctatcggcttcagggcttagatggtgaagcaactgagcctatgattaaagaattggaa
gaagatagagaggagtcacaagatccagaggttgagtttgccattgcaggtgctgttcgt
gagtatggtgggctggaaattatattgagcatgatccagcatctgcgagatgatttcaag
tccaaccaagagcagttggtagctgttctaaatctcctcatgcattgttgtaaaataaga
gagaacagacgagctttgctgaggttaggagctttaggtctactccttgaaacggcaaga
catgccttttctgttgatgccatggagccagctgaaggcatacttctcattgttgagagt
ctgactatggaagctaatgaaagtgataacattagcatcacacaaagtgctcttactgtc
actagtgaagagaccggtgaacaggccaagaaaatagtcctcatgtttctggagagatta
tctcatcctttgggccttaagaaatcaaacaaacagcagaggaacaatgagatggttgca
agaatcttgccctacttgacatatggtgaacctgctgcaatggaagtgcttatccagcac
ttcagcccacccttgcaggactggaaggaatatgatcggctgcaaagagaacatgaagat
gacccaaaagatgaaagcattgcccagcaagctgccaagcaaaggtttacgttggaaaat
tttgtaagggtatctgagtctcttaaaacaagttcctgcggagatagactgaaagacatt
attcttgagaggggcattactggcgttgcagttagacatctgagggatagtttttcagct
gcgggacaggctggctttaaatctagtgcagaatgggcaatgggcttgacactgccatct
gtcccactgatattgtctatgctgagaggcttgtcgacaggacatttggccactcaaaag
tgtattgatgagggagggattttacctttacttcatgctttggaaggggtcgcgggggaa
aacgagataggcgcgagggctgaaaacttattggacaccctttcaaataaggagggaaaa
ggagatggctttttggaggagaaggtgcggaggttgagacatgccaccagggatgaaatg
aggcgtagagctctaaggaaaagagaggaactgcttcagggtcttggaatgcgacaagag
ctagcttcagatggcggtgagcgtattgttgtttcacgaccattacttgaaggtttagaa
gacgtggaggaagaggaggatggcttagcatgcatggtttgccgagagggttacagtctg
aggcctactgacctacttggtgtttactcttatagcaagcgagtgaatttaggtgcaggg
acttctggaagtgcacgtggggagtgtgtttatacaactgttagttatttcaacattatt
catttccagtgccatcaggaagccaagagagcagacgctgctctgaaaaatccaaagaag
gagtgggaaggagctactctcagaaataatgaatctctttgcaattctttgttccctgtg
agaggtccgtctgttcctttagcgcagtatgttcgctatgttgaccagtactgggacaac
ctcaatgctcttggacgtgctgatggaagccgccttcggctgttgacttatgacattgtt
ctgatgctagctcgatttgcgaccggggcatcatttagtgcagaatgcagaggtggtgga
agggaaagcaactccagatttctacctttcatgatccaaatggcacgtcaccttctcgat
cagggaagcccatcccagcgtcatacaatggccaagtctctgacagcatatttgtcatcg
tctgcatcagattctaggacttctactcctgagaaacaaccgtctatgggatctgaagaa
actgtccagtttatgatggtgacttcacttctttcagagtctcatgaatcctggttgcaa
caccgccgtgccttcttgcagcgtggaatataccatgcctacatgcagcacactcatggt
cggtcggcaggtcgcacatcatccagttcatctcctatagtcaatatagagtctggtaat
acaagccaaagtcctagtgcagagattgggggtgccgatgagcttctgtccgttattcga
ccaatgcttgtctacactggcttgattgagcagttgcaacgtttcttcaaggtcaaaaaa
ccaccaaatgcggcaccagccccaacagaaggtacatcgagagtatctgaaggggatgac
ttggaagtttgggaggtagtgatgaaagagcggctttcgaacgtaaaggagatggtggat
ttctcgaaggaaatgctatcatggcttgacgagatgagttccgcgagcgatttgcaggag
gcatttgacataatcggtgttttagcggatgtgctgtctggtgccattaccaactgtgag
gactttgtacgtgcagcaatcgatgcggggcgaggctga

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