KEGG T01031: 100010818

Monodelphis domestica (gray short-tailed opossum): 100010818

Entry

100010818         CDS       T01031

Symbol

UGT2A1, UGT2B17

Name

(RefSeq) UDP-glucuronosyltransferase 2A1

K00699

glucuronosyltransferase [EC:2.4.1.17]

Organism

mdo Monodelphis domestica (gray short-tailed opossum)

Pathway

mdo00040

Pentose and glucuronate interconversions

mdo00053

Ascorbate and aldarate metabolism

mdo00140

Steroid hormone biosynthesis

mdo00830

Retinol metabolism

mdo00860

Porphyrin metabolism

mdo00980

Metabolism of xenobiotics by cytochrome P450

mdo00982

Drug metabolism - cytochrome P450

mdo00983

Drug metabolism - other enzymes

mdo01100

Metabolic pathways

mdo01240

Biosynthesis of cofactors

mdo04976

Bile secretion

mdo05204

Chemical carcinogenesis - DNA adducts

mdo05207

Chemical carcinogenesis - receptor activation

Module

mdo_M00014

Glucuronate pathway (uronate pathway)

mdo_M00129

Ascorbate biosynthesis, animals, glucose-1P => ascorbate

Brite

KEGG Orthology (KO) [BR:mdo00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    100010818 (UGT2A1)
   00053 Ascorbate and aldarate metabolism
    100010818 (UGT2A1)
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100010818 (UGT2A1)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100010818 (UGT2A1)
   00860 Porphyrin metabolism
    100010818 (UGT2A1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100010818 (UGT2A1)
   00982 Drug metabolism - cytochrome P450
    100010818 (UGT2A1)
   00983 Drug metabolism - other enzymes
    100010818 (UGT2A1)
09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    100010818 (UGT2A1)
09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    100010818 (UGT2A1)
   05207 Chemical carcinogenesis - receptor activation
    100010818 (UGT2A1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:mdo01003]
    100010818 (UGT2A1)
Enzymes [BR:mdo01000]
2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     100010818 (UGT2A1)
Glycosyltransferases [BR:mdo01003]
Others
  Hydrophobic molecule
   100010818 (UGT2A1)

SSDB

Motif

Pfam:

UDPGT EryCIII-like_C Glyco_tran_28_C Pro_3_hydrox_C

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

5:154663938..154898203

AA seq 557 aa
MLPHRDADLYGKKKLFTLDSTKVSTSRSTMLGKNSLLLALQMTLLGTVFGGNVLIWPMEG
SHWLNIKIILGKLIEKHHNVTVLVASGALFISPINESSWKSEVYKVPFGKEKIEGVIRNF
VLTWLENMPSPATLWQFYSEMTKVIHEFHQVSQAMCDGVLTNLKLMEKLQKGKFDILISD
PVFPCGDLVALKLGIPFVYSLRFSPASTVEKHCGKVPYPPSYVPAVLSELTDKMSFSDRI
RNFVSYHLQDYMFNTLWSPWDSYYSKILGRPTTLCETMGKAEMWLIRTYWDFEFPRPYLP
NFEFVGGLHCKPAKPLPEEMEKFVQSSGDHGIVVFSLGSMVKNLTDEKSNVIAAALAQIP
QKVLWRYKGKKPATLGPNTKTYDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVG
VPMFADQPDNIAHMKAKGAAVEVNFNKMTTADLLNALKTVINDPSYKENAMRLSRIHHDQ
PVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVVFIVAKSC
LFCCRKFGKTGKKQKRA

NT seq 1674 nt +upstreamnt +downstreamnt
atgctgccacacagagatgctgacttatatggaaaaaaaaaactctttactttggattcc
accaaggtttccacatcaaggtccaccatgttggggaaaaacagcttgttactggctctt
cagatgacactactgggaacagtctttgggggaaatgtcctcatttggccaatggaaggt
agtcactggcttaatattaagataattttagggaaattgatagaaaaacatcacaatgtc
acagtattggttgcttctggagcactgttcatttcacctattaatgagtcctcttggaag
tctgaagtatataaagtgccctttggaaaggaaaaaatagagggtgtcatcaggaatttt
gttctcacatggctggaaaatatgccctccccagcaaccctctggcaattctactcggaa
atgaccaaagtcattcatgagttccaccaagtgagccaagcaatgtgtgatggtgtactt
accaatctgaagttaatggaaaaactacagaaaggcaaatttgatatcttgatctcagat
ccagtattcccctgtggcgacctggttgctcttaaactaggaatcccatttgtatactcc
ttgagattctctccagcctccaccgtggaaaaacattgtgggaaagttccatatcctcct
tcttatgttcctgctgtcttgtcggagctcactgacaaaatgtcttttagtgacagaata
agaaactttgtctcctaccatttacaggactacatgtttaatactctttggtcaccatgg
gactcctactatagcaaaattttgggaagaccaactacattatgtgaaaccatggggaaa
gctgaaatgtggctgattcgaacgtactgggattttgaatttcctcgtccttacttgcca
aattttgagtttgtgggaggactccactgtaaacctgccaagcctcttcctgaggaaatg
gaaaaatttgtccagagctctggggaccatggtattgtggtgttttctcttgggtcaatg
gtgaaaaacttaactgatgaaaagagtaatgtgattgctgcagctcttgcccagattcca
cagaaggttctgtggcgatacaaaggaaagaagccagccacattaggtccaaataccaaa
acctatgactggattccccagaatgatcttcttggtcaccccaaaaccaaggcttttatc
actcatggtggaaccaatggaatctacgaagctatctatcatggaattcccatggtaggc
gtacccatgtttgctgatcagcctgataacattgctcacatgaaggccaagggagcagct
gtcgaggtgaactttaataaaatgacaacagctgacctgcttaatgctttgaagacagtc
atcaatgatccttcatacaaagaaaatgctatgagattatcaagaattcatcatgaccaa
cctgtgaaacccctagatcgagctgtcttctggatcgagtttgtgatgcgtcacaaaggt
gctaagcaccttcgacctgctgcccatgacctcacctggtaccagtaccattccttggat
gtgattggcttcctacttgcctgtgtggcaactgttgtctttatagttgctaaatcctgc
ttgttttgctgccggaaatttggtaaaacaggaaagaaacaaaagagggcataa

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