KEGG   Monodelphis domestica (gray short-tailed opossum): 100030463
Entry
100030463         CDS       T01031                                 
Symbol
ADCY1
Name
(RefSeq) adenylate cyclase 1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo00230  Purine metabolism
mdo01100  Metabolic pathways
mdo01522  Endocrine resistance
mdo04015  Rap1 signaling pathway
mdo04020  Calcium signaling pathway
mdo04022  cGMP-PKG signaling pathway
mdo04024  cAMP signaling pathway
mdo04062  Chemokine signaling pathway
mdo04072  Phospholipase D signaling pathway
mdo04081  Hormone signaling
mdo04082  Neuroactive ligand signaling
mdo04114  Oocyte meiosis
mdo04211  Longevity regulating pathway
mdo04213  Longevity regulating pathway - multiple species
mdo04261  Adrenergic signaling in cardiomyocytes
mdo04270  Vascular smooth muscle contraction
mdo04371  Apelin signaling pathway
mdo04540  Gap junction
mdo04611  Platelet activation
mdo04713  Circadian entrainment
mdo04714  Thermogenesis
mdo04720  Long-term potentiation
mdo04723  Retrograde endocannabinoid signaling
mdo04724  Glutamatergic synapse
mdo04725  Cholinergic synapse
mdo04727  GABAergic synapse
mdo04750  Inflammatory mediator regulation of TRP channels
mdo04911  Insulin secretion
mdo04912  GnRH signaling pathway
mdo04913  Ovarian steroidogenesis
mdo04914  Progesterone-mediated oocyte maturation
mdo04915  Estrogen signaling pathway
mdo04916  Melanogenesis
mdo04918  Thyroid hormone synthesis
mdo04921  Oxytocin signaling pathway
mdo04923  Regulation of lipolysis in adipocytes
mdo04925  Aldosterone synthesis and secretion
mdo04926  Relaxin signaling pathway
mdo04927  Cortisol synthesis and secretion
mdo04928  Parathyroid hormone synthesis, secretion and action
mdo04934  Cushing syndrome
mdo04935  Growth hormone synthesis, secretion and action
mdo04970  Salivary secretion
mdo04971  Gastric acid secretion
mdo04972  Pancreatic secretion
mdo04976  Bile secretion
mdo05032  Morphine addiction
mdo05142  Chagas disease
mdo05146  Amoebiasis
mdo05163  Human cytomegalovirus infection
mdo05166  Human T-cell leukemia virus 1 infection
mdo05200  Pathways in cancer
mdo05207  Chemical carcinogenesis - receptor activation
mdo05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100030463 (ADCY1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100030463 (ADCY1)
   04371 Apelin signaling pathway
    100030463 (ADCY1)
   04020 Calcium signaling pathway
    100030463 (ADCY1)
   04072 Phospholipase D signaling pathway
    100030463 (ADCY1)
   04024 cAMP signaling pathway
    100030463 (ADCY1)
   04022 cGMP-PKG signaling pathway
    100030463 (ADCY1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100030463 (ADCY1)
   04081 Hormone signaling
    100030463 (ADCY1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100030463 (ADCY1)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100030463 (ADCY1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100030463 (ADCY1)
   04062 Chemokine signaling pathway
    100030463 (ADCY1)
  09152 Endocrine system
   04911 Insulin secretion
    100030463 (ADCY1)
   04923 Regulation of lipolysis in adipocytes
    100030463 (ADCY1)
   04912 GnRH signaling pathway
    100030463 (ADCY1)
   04913 Ovarian steroidogenesis
    100030463 (ADCY1)
   04915 Estrogen signaling pathway
    100030463 (ADCY1)
   04914 Progesterone-mediated oocyte maturation
    100030463 (ADCY1)
   04921 Oxytocin signaling pathway
    100030463 (ADCY1)
   04926 Relaxin signaling pathway
    100030463 (ADCY1)
   04935 Growth hormone synthesis, secretion and action
    100030463 (ADCY1)
   04918 Thyroid hormone synthesis
    100030463 (ADCY1)
   04928 Parathyroid hormone synthesis, secretion and action
    100030463 (ADCY1)
   04916 Melanogenesis
    100030463 (ADCY1)
   04925 Aldosterone synthesis and secretion
    100030463 (ADCY1)
   04927 Cortisol synthesis and secretion
    100030463 (ADCY1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100030463 (ADCY1)
   04270 Vascular smooth muscle contraction
    100030463 (ADCY1)
  09154 Digestive system
   04970 Salivary secretion
    100030463 (ADCY1)
   04971 Gastric acid secretion
    100030463 (ADCY1)
   04972 Pancreatic secretion
    100030463 (ADCY1)
   04976 Bile secretion
    100030463 (ADCY1)
  09156 Nervous system
   04724 Glutamatergic synapse
    100030463 (ADCY1)
   04727 GABAergic synapse
    100030463 (ADCY1)
   04725 Cholinergic synapse
    100030463 (ADCY1)
   04720 Long-term potentiation
    100030463 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    100030463 (ADCY1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100030463 (ADCY1)
  09149 Aging
   04211 Longevity regulating pathway
    100030463 (ADCY1)
   04213 Longevity regulating pathway - multiple species
    100030463 (ADCY1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100030463 (ADCY1)
   04714 Thermogenesis
    100030463 (ADCY1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100030463 (ADCY1)
   05207 Chemical carcinogenesis - receptor activation
    100030463 (ADCY1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100030463 (ADCY1)
   05163 Human cytomegalovirus infection
    100030463 (ADCY1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100030463 (ADCY1)
   05142 Chagas disease
    100030463 (ADCY1)
  09165 Substance dependence
   05032 Morphine addiction
    100030463 (ADCY1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100030463 (ADCY1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100030463 (ADCY1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100030463 (ADCY1)
Enzymes [BR:mdo01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100030463 (ADCY1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom Peptidase_M48
Other DBs
NCBI-GeneID: 100030463
NCBI-ProteinID: XP_007500638
Ensembl: ENSMODG00000010195
LinkDB
Position
6:complement(273539904..273907321)
AA seq 1166 aa
MHGTDMEETPFRKVKTKRRKCPPCGCAPSGGSPVLLEAIACEDEFDCKELESLFRNYNLK
LEQTSTLKALAVLIVLTGTLALGELMSGPSLTISKGSHPVHCIIFLSLFIVTNVKYLQVT
QLQQIVKLILLFSFTFAFLCCPFSLGAYGIEPPTSPEEGMWQLMLVTFVSYSLLPVRSLL
AIIFGIVVSVSHLIVTATSVTAKRHRLWRTLGANALLFVSVNLYGVFVRILTERAQRKAF
LQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVS
ILFADIVGFTSLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQP
KTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDV
TLANVMETGGLPGKVHITKTTLECLNGDYEVEPGFGHERNSFLKKHNIETFFIVPSHRRK
IFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTAS
EKLRNRSSFSTNVVYTTPGTRVNRYISRLIEARQTESEMADLNFFTLQYKHKEREEKYHQ
LQDEYFTSAVVLSLVLAALFGLVYLLIIPQSIIVLVLLVFCICFLVACIMYLHVTRVQVN
VLFCHYITVPLKTEVWILFLLFLNHLNSDAFIFLVLSFLIFEIKRWNIITLQGFLFYAPF
FLFSQVGCMPWSWNTNSSSSLVIISSGGMNKTRNVLPCDTAHHAFLSCIVGTLTLAIFLR
VSSLPKMILLFLVTVLYILVLELSGYRKAVGGGAFYLRGYEPILAILLFSCALALHARQV
DLKLRLDYLWAVQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYS
QVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKEFYKDLEKIKTIGST
YMAAVGLVPTTGTKAKKSIYSHLSTLADFAIEMFNVLDEINYQSYNDFVLRVGINVGPVV
AGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTEEVHRLLKRCSYEFTCRGKVSVKG
KGEMLTYFLEGKANGSNSQTRSLNLERKMYPCGKSNIQTKLGTSCPSVSSVANFTVKAGI
GALQTAGTHTNPTLHYLPSVPAVKEA
NT seq 3501 nt   +upstreamnt  +downstreamnt
atgcatggcactgacatggaggaaacaccgtttcggaaagtcaaaacgaagaggaggaag
tgtccgccctgcggctgcgccccctcggggggctccccggtgcttctggaggccatcgcg
tgcgaggacgagttcgactgcaaggagctcgagtcccttttccggaattacaacctgaaa
ctggaacagacctccacgctcaaggcgctggctgtgctcattgtcctgacgggcaccctg
gccctgggggagctcatgtccggacccagcctgaccatctccaagggttcgcaccccgtg
cattgcatcatcttcctctccctcttcatcgttaccaatgtcaagtacttacaggtcacc
cagctccagcaaatcgtcaaactcatactgctcttcagtttcaccttcgcctttctctgc
tgccccttttcgctgggggcctacggcatcgagccccccacgtccccagaagagggaatg
tggcaactcatgctagtcaccttcgtttcctactccttgctgccagtgcggagtcttctg
gccatcatctttgggatagtggtgtccgtctcccacctcatcgtaactgccacttcagtg
actgccaagagacacagactctggaggacgcttggggcaaatgctctgctttttgtcagt
gtaaatttgtatggggtctttgtgaggattttgacagaaagggctcagaggaaggctttc
ctacaggccaggaactgcatagaggacaggctgaggctggaagatgaaaatgaaaaacag
gaacgactcctgatgagtcttttgcccagaaatgttgccatggaaatgaaggaagatttt
ctgaagccacctgagagaatttttcacaagatttacattcaaaggcatgacaatgtcagc
attttgtttgcagatattgtgggtttcactagtttggcatcccagtgcacagctcaagag
ctggtgaagcttctgaatgaactctttgggaagtttgatgaattggccacagaaaaccac
tgcagacgaattaaaatcctgggggattgctactattgtgtgtcaggactgacccaaccc
aaaaccgaccatgcccattgctgtgtcgaaatggggctggacatgattgacaccatcacg
tctgttgcagaagccactgaagttgacctgaacatgagagtgggcctgcatacaggccgt
gtcctatgtggggtgctaggacttcgaaagtggcaatatgatgtctggtcaaatgatgtg
accctagcaaatgtaatggagactggaggattacctgggaaggttcatatcacaaagacg
accttagagtgcctaaatggggactatgaggtagaaccaggttttggacatgagaggaac
agtttcttgaaaaaacacaatattgaaaccttttttattgtaccatcccatcggagaaag
atatttcctggacttattctctcagatataaagccagctaaaaggatgaagttcaaaacg
gtttgttacttgttggtccagctaatgcactgtcggaagatgtttaaagcagaaattcct
ttctccaatgtcatgacctgtgaggatgatgacaagagaagggctttaaggacagcatct
gaaaaactcaggaatcgatcctctttttctacaaacgttgtatataccactccaggaacg
cgagtaaacagatatatcagccgtttgatagaagccaggcaaacagagtctgagatggca
gatttgaatttctttaccctacagtacaaacataaagaacgggaagaaaaatatcaccag
cttcaagatgagtatttcaccagtgctgtggtcctttcactggttctagctgccttattt
ggccttgtctaccttctaataatcccacagagtatcatcgtcctggttctcctggtgttc
tgcatatgcttcctggtggcttgtattatgtatctacatgtcacacgagtacaggtcaat
gttcttttttgccactatattactgtgcctctgaagactgaggtttggattctgtttctg
ctgtttcttaaccacctgaactcggatgcctttatttttctagtccttagttttctgatc
tttgaaataaagagatggaacattattactttacaaggttttcttttctatgcccctttc
ttcctattctcccaggtgggctgcatgccttggtcatggaacactaattccagcagctcc
ttagtgatcatttcttctggaggaatgaataagacaaggaatgtgctgccctgtgacaca
gcccatcacgcattcctttcctgcattgtggggactttgactctggcaatatttctccgt
gtctcttcattgccaaaaatgatccttctctttttagttacagtcttatatatacttgtt
ttggagctcagtggatatagaaaagcagtagggggtggagccttttacctccgtggatat
gaacccatattggctattttgctgttttcctgtgcgctggcccttcatgccaggcaggtg
gacttgaagttacgtctggactacctctgggctgtgcaggcggaagaggagcgagatgac
atggagagagtgaaactagacaataaacggattctcttcaaccttttgccagcccatgtt
gcacagcactttcttatgtctaatcccaggaacatggacctttattatcagtcctattca
caagtgggtgtgatgtttgcttccatcccaaatttcaacgatttctacatcgaactggat
ggcaataacatgggagtggaatgtttgcgtctcttaaatgaaatcattgctgattttgat
gagctcatggacaaagaattttacaaggacctagaaaagatcaagacaattggaagtaca
tatatggcagcagtgggactagtgccaaccacaggaaccaaggccaagaagtcaatttat
tcacatctgagcacgctagctgattttgcaatagagatgttcaatgtccttgatgaaatc
aattatcaatcttacaacgactttgtgctccgtgttggaattaatgtaggtcctgtagtg
gcaggtgttattggtgccagaagacctcaatatgatatctggggaaatactgttaatgtt
gccagtcgaatggatagtactggagtgcagggaaaaattcaggtcacagaagaagtccac
cggttactaaagcggtgtagctatgaatttacatgtcgagggaaagtcagtgtcaaggga
aaaggtgaaatgttgacctattttctggaaggaaaagcaaatggaagtaattctcaaacc
agatccttaaacttagaacggaaaatgtatccatgtgggaaatcaaacattcagacaaaa
ctgggaaccagctgcccttctgtctcatctgtggctaactttacagtcaaagctgggatt
ggagccctgcagacagcaggcacccataccaatccaacgcttcattaccttccttctgtg
ccagctgtgaaagaagcctag

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