Monodelphis domestica (gray short-tailed opossum): 100032356
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Entry
100032356 CDS
T01031
Symbol
ITCH
Name
(RefSeq) itchy E3 ubiquitin protein ligase
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo04120
Ubiquitin mediated proteolysis
mdo04144
Endocytosis
mdo04330
Notch signaling pathway
mdo04668
TNF signaling pathway
mdo04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100032356 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100032356 (ITCH)
04668 TNF signaling pathway
100032356 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100032356 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100032356 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mdo04131
]
100032356 (ITCH)
04121 Ubiquitin system [BR:
mdo04121
]
100032356 (ITCH)
Enzymes [BR:
mdo01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
100032356 (ITCH)
Membrane trafficking [BR:
mdo04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100032356 (ITCH)
Ubiquitin system [BR:
mdo04121
]
Ubiquitin ligases (E3)
HECT type E3
100032356 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
100032356
NCBI-ProteinID:
XP_007474281
Ensembl:
ENSMODG00000002732
UniProt:
F6Z7A1
LinkDB
All DBs
Position
1:387745189..387930272
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AA seq
901 aa
AA seq
DB search
MRGASSFHPDPVLSQILWGIPSQVHSPVGGMSGSSSRSGSVGGLTMKSQLQIIVISAKLK
ENKKNWFGPSPYVEVSVDGQSKKTEKCSNTNSPKWKQPLTVIVTPISKLNFRVWSHQTLK
SDVLLGSAALDIHETLKSNNMKLDEVIVTLHLVGDKEPTEIIGDLSVCLDGLQVDPDILT
NGYATSSEGSSQSDDSRTRNDTRSNTNGPENAEEPGCSDNRKVNGSSSPSLTNGGFKPSR
PPRPSRPPPPTPRRPASVNGSPAPSETPVSSTDSSPSTSMSVIPEGATAGTSVPTTVALT
TPPTSRQVQSVNSASQQLNTVNQGPLPPGWEQRVDQHGRVYYVDHVEKRTSWDRPEPLPP
GWERRVDNMGRVYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGN
QDLFTSSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPE
GWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVHYFRFWCQQL
AMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSH
EVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLP
FYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHELKP
NGSNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLL
CGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGF
ADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQ
E
NT seq
2706 nt
NT seq
+upstream
nt +downstream
nt
atgagaggagcaagcagtttccatcctgaccctgttctgagccagatactttggggaatt
ccctctcaggtccatagcccagttggtggcatgtctggcagtagttcacggtcagggtct
gtggggggattgaccatgaaatcacaacttcagatcattgtcatctcagcaaaacttaaa
gaaaataaaaagaactggtttgggccaagtccttatgtggaagtctcagtagatggacag
tcaaagaagacagaaaaatgcagcaataccaacagtcccaagtggaagcaacctcttact
gtaattgtcacacctatcagcaaattaaattttcgtgtatggagtcatcagacattaaaa
tccgatgttttactgggaagtgctgctctagatattcatgaaacgttaaaatcaaataat
atgaaacttgatgaagtgattgtgacattacatcttgtgggtgacaaggagccaacagaa
atcataggagacctgtcagtttgtcttgatggactacaagtagatcctgatattctaaca
aatggctatgccacatcttcagaaggtagttcacagagtgatgattccagaaccaggaat
gatacaagatcaaatacaaatggacctgaaaatgctgaggaaccaggatgcagtgataat
aggaaggtcaatggcagcagttctccatcactcacaaatggaggttttaaaccttctagg
cctccaagaccttcaaggccacctcctcctactccccgtcgaccagcatctgtcaatggt
tctcctgcaccatctgaaactcctgtatctagtacagattcatcaccttcaacaagtatg
agtgtaattcccgaaggagcaacagctggaacatcagttcctaccactgtggctttaaca
acacctccaacttctagacaagtgcagtcagtaaattctgcttctcaacaactcaataca
gttaatcaaggtcctcttccgcctggttgggaacagagagtggaccaacatggacgagtc
tactatgtagatcatgttgaaaaaagaacatcgtgggatagaccagaacctcttccacct
ggctgggaacgtcgagttgacaacatgggacgtgtttattatgttgaccactttacaaga
actacaacttggcaacggccaactttggaatcagttagaaactatgagcagtggcaacta
cagcgaagtcaactccaaggagcaatgcaacaatttaaccagagattcatttatgggaat
caagacttgtttacttcatctcagaataaagaatttgatcctcttggacctctgccacca
ggatgggaaaagagaacagatagtaatggcagagtgtatttcgtcaatcacaacacacgt
attacacagtgggaagatcctagaagtcagggccaattaaatgagaagcctttaccagaa
ggctgggaaatgagatttacagtggatgggattccatattttgtggatcacaataggaga
acaacaacatatatagatcctagaactggaaaatctgctctagacaatggaccccaaata
gcctatgttagagattttaaagcaaaggtccattatttccgtttctggtgtcagcaactg
gctatgccacagcacatcaagattacagtgacaagaaaaactttgtttgaagattccttt
cagcagataatgagtttcaatccccaggatcttcgaagacgtttgtgggtgatttttcca
ggagaagaaggtttagattatggaggtgtggcaagagaatggttctttcttttgtcacat
gaagtgctgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgcttg
cagataaatccagcttcttatattaatccagatcatctgaaatacttccgttttattggc
aggtttattgccatggcattattccatggaaaattcatagacacaggcttttctttgcca
ttctataaacgtatcttgaacaaaccagttggactcaaagacttagaatctattgatcca
gaattttacaattctctcatctgggttaaagaaaacaacattgaagaatgtggtttagag
atgtacttctcagttgataaggaaattcttggtgaaattaagagtcatgaactgaaaccc
aatggcagtaatatactagtaacagaagaaaataaagaagaatatattagaatggtagca
gaatggagattatctcgaggtgttgaagagcagacacaagctttctttgaaggcttcaat
gaaattctcccacagcagtacctgcaatactttgatgctaaagaactagaggtacttttg
tgtggaatgcaagagattgacttaaatgactggcaaagacatgccatctaccgacattat
actaggacaagcaaacaaatcatgtggttttggcagtttgtgaaagaaattgacaatgag
aagagaatgagactgttgcagtttgttacgggaacatgcagattgccagttgggggattt
gctgacctcatggggagcaatggacctcaaaagttttgcattgaaaaagttggcaaagaa
aattggttacctagaagtcacacctgttttaaccgcttggatctgccaccctacaagagc
tatgaacaactgaaggaaaaactgttatttgccattgaggaaacagaaggatttggacaa
gagtga
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