Myotis daubentonii (Daubenton's bat): 132220949
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Entry
132220949 CDS
T10294
Symbol
HSD11B1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1 isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
mdt Myotis daubentonii (Daubenton's bat)
Pathway
mdt00140
Steroid hormone biosynthesis
mdt00980
Metabolism of xenobiotics by cytochrome P450
mdt01100
Metabolic pathways
mdt05204
Chemical carcinogenesis - DNA adducts
Module
mdt_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
mdt00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
132220949 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
132220949 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
132220949 (HSD11B1)
Enzymes [BR:
mdt01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
132220949 (HSD11B1)
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Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
Shikimate_DH
DUF1776
Pyr_redox_2
2-Hacid_dh_C
NAD_binding_2
Pyr_redox_3
AdoHcyase_NAD
Pyr_redox
Motif
Other DBs
NCBI-GeneID:
132220949
NCBI-ProteinID:
XP_059530689
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All DBs
Position
18:13397299..13425631
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AA seq
292 aa
AA seq
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MACMKNYILPILGIFLAYYYYSADEEFKPEMLQGKKVIVTGASKGIGKEMAYHLAKMGAH
VMVTARSEEALKKIVSDCLKYGAASAHYIAGTMEDMTFAEQFIAKAGKILGGLDMLILNH
ITSATMEPFAGDIHLVRRSVEVNYISYVVMSMAALPMLKQSNGSIVVVSSMAGKMASPLV
APYSASKFALDGFFSSIRTEFSVTKVNVSITLCILGLIDTDSAMKAVSGILNTEAAPKED
CALEIIKRGALRQEEMYYGKVGWTSLLLKNPGRRILEFLSLRNYNMEKFINN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttgtatgaaaaactatatcctacccattctggggatcttcttggcctactactac
tattccgcggatgaggaattcaaaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaggggattggaaaagagatggcctatcatctggcgaagatgggagcccac
gtgatggtgacagcgaggtcagaagaagctctaaagaagatagtatccgactgcttgaag
tatggagcagcctcagcacactacattgctggcaccatggaggacatgaccttcgcagag
caatttattgccaaagctggaaagatcttgggaggactagacatgctcattctcaatcac
atcaccagcgctaccatggaaccatttgctggtgatatccacttagtgcgcagaagcgtg
gaggtcaactacatcagttatgtggtcatgagtatggctgccctacccatgctgaagcag
agcaacggaagcattgtcgttgtctcctccatggctgggaaaatggctagtccacttgtt
gctccctattctgcaagcaagtttgctctcgatgggtttttctcctccatcaggacggaa
ttttcagtgaccaaggtcaatgtgtcaatcactctctgtatcctcggcctcatagacaca
gactcagccatgaaggcagtgtctgggatactcaacaccgaggcagctccaaaggaagac
tgtgccttggagatcatcaaaaggggagctctacgccaagaggaaatgtattatggcaaa
gtaggatggaccagtctcctgctgaaaaatccagggaggaggatcctggaattcctcagc
ctacgaaattataatatggaaaaatttataaacaactag
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